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https://www.readbyqxmd.com/read/27924340/exosome-like-silica-nanoparticles-a-novel-ultrasound-contrast-agent-for-stem-cell-imaging
#1
Fang Chen, Ming Ma, Junxin Wang, Fang Wang, Shi-Xiong Chern, Eric Ruike Zhao, Anamik Jhunjhunwala, Sean Darmadi, Hangrong Chen, Jesse V Jokerst
Ultrasound is critical in many areas of medicine including obstetrics, oncology, and cardiology with emerging applications in regenerative medicine. However, one critical limitation of ultrasound is the low contrast of target tissue over background. Here, we describe a novel cup-shaped silica nanoparticle that is reminiscent of exosomes and that has significant ultrasound impedance mismatch for labelling stem cells for regenerative medicine imaging. These exosome-like silica nanoparticles (ELS) were created through emulsion templating and the silica precursors bis(triethoxysilyl)ethane (BTSE) and bis(3-trimethoxysilyl-propyl)amine (TSPA)...
December 7, 2016: Nanoscale
https://www.readbyqxmd.com/read/27922526/air-pollutant-exposure-within-a-few-days-of-delivery-and-placental-abruption-in-japan
#2
Takehiro Michikawa, Seiichi Morokuma, Shin Yamazaki, Kotaro Fukushima, Kiyoko Kato, Hiroshi Nitta
BACKGROUND: Placental abruption is an emergency obstetric complication. Although the etiology of abruption is not fully understood, acute stimuli, such as ischemia and/or inflammation, are associated with rupture of the decidual artery, resulting in placental separation. Ischemia and inflammation are acute biologic effects of air pollution. Using a case-crossover design, we tested the hypothesis that a short-term increase in exposure to air pollutants is a potential trigger of placental abruption...
December 1, 2016: Epidemiology
https://www.readbyqxmd.com/read/27920246/beyond-utilization-measuring-effective-coverage-of-obstetric-care-along-the-quality-cascade
#3
Elysia Larson, Daniel Vail, Godfrey M Mbaruku, Redempta Mbatia, Margaret E Kruk
OBJECTIVE: To determine the effective coverage of obstetric care in a rural Tanzanian region and to assess differences in effective coverage by wealth. DESIGN: Cross-sectional structured interviews. SETTING: Pwani Region, Tanzania. PARTICIPANTS: The study includes 24 rural, government-managed, primary healthcare clinics and their catchment populations. From January-April 2016, we conducted a household survey of a census of women with recent deliveries, health worker knowledge surveys and facility audits...
December 4, 2016: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/27919934/development-and-validation-of-risk-prediction-model-for-venous-thromboembolism-in-postpartum-women-multinational-cohort-study
#4
Alyshah Abdul Sultan, Joe West, Matthew J Grainge, Richard D Riley, Laila J Tata, Olof Stephansson, Kate M Fleming, Catherine Nelson-Piercy, Jonas F Ludvigsson
OBJECTIVE:  To develop and validate a risk prediction model for venous thromboembolism in the first six weeks after delivery (early postpartum). DESIGN:  Cohort study. SETTING:  Records from England based Clinical Practice Research Datalink (CPRD) linked to Hospital Episode Statistics (HES) and data from Sweden based registry. PARTICIPANTS:  All pregnant women registered with CPRD-HES linked data between 1997 and 2014 and Swedish medical birth registry between 2005 and 2011 with postpartum follow-up...
December 5, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27916235/the-rohingya-people-of-myanmar-health-human-rights-and-identity
#5
REVIEW
Syed S Mahmood, Emily Wroe, Arlan Fuller, Jennifer Leaning
The Rohingya people of Myanmar (known as Burma before 1989) were stripped of citizenship in 1982, because they could not meet the requirement of proving their forefathers settled in Burma before 1823, and now account for one in seven of the global population of stateless people. Of the total 1·5 million Rohingya people living in Myanmar and across southeast Asia, only 82 000 have any legal protection obtained through UN-designated refugee status. Since 2012, more than 159 000 people, most of whom are Rohingya, have fled Myanmar in poorly constructed boats for journeys lasting several weeks to neighbouring nations, causing hundreds of deaths...
December 1, 2016: Lancet
https://www.readbyqxmd.com/read/27911959/barriers-to-timely-and-safe-blood-transfusion-for-pph-patients-evidence-from-a-qualitative-study-in-dhaka-bangladesh
#6
Sadika Akhter, Iqbal Anwar, Rashida Akter, Feroza Akhter Kumkum, Monjura Khatun Nisha, Fatema Ashraf, Ferdousi Islam, Nazneen Begum, Mahbub Elahi Chowdhury, Anne Austin, Syed Shariful Islam, Aminur Rahman
BACKGROUND AND OBJECTIVES: In Bangladesh, postpartum hemorrhage (PPH) is the leading cause of maternal mortality accounting for 31% of all blood transfusions in the country. Although safe blood transfusion is one of the 8 signal functions of Comprehensive Emergency Obstetric Care (CEmOC) strategy, most of the designated public sector CEmOC facilities do not have on-site blood storage system. Emergent blood is mainly available from external blood banks. As a result, emergent patients are to rely on an unregulated network of brokers for blood which may raise question about blood safety...
2016: PloS One
https://www.readbyqxmd.com/read/27910107/gestating-times-women-s-accounts-of-the-temporalities-of-pregnancies-that-end-in-abortion-in-england
#7
Siân M Beynon-Jones
Tensions between the 'clock time' of medicine and the embodied times of its subjects are central to feminist writing concerning Western obstetric practice. In this article, I expand the focus of this literature by addressing the temporal dynamics of another site of reproductive healthcare: abortion provision. Echoing obstetric accounts of birth, time in legal, healthcare and social scientific discourse on abortion is routinely conceptualised as a finite resource contained within the pregnant/foetal body, which can be measured using clocks and calendars...
December 2, 2016: Sociology of Health & Illness
https://www.readbyqxmd.com/read/27895842/postoperative-outcome-of-caesarean-sections-and-other-major-emergency-obstetric-surgery-by-clinical-officers-and-medical-officers-in-malawi
#8
Garvey Chilopora, Caetano Pereira, Francis Kamwendo, Agnes Chimbiri, Eddie Malunga, Staffan Bergström
BACKGROUND: Clinical officers perform much of major emergency surgery in Malawi, in the absence of medical officers. The aim of this study was to validate the advantages and disadvantages of delegation of major obstetric surgery to non-doctors. METHODS: During a three month period, data from 2131 consecutive obstetric surgeries in 38 district hospitals in Malawi were collected prospectively. The interventions included caesarean sections alone and those that were combined with other interventions such as subtotal and total hysterectomy repair of uterine rupture and tubal ligation...
September 2016: Malawi Medical Journal: the Journal of Medical Association of Malawi
https://www.readbyqxmd.com/read/27886436/factors-that-hinder-or-enable-maternal-health-strategies-to-reduce-delays-in-rural-and-pastoralist-areas-in-ethiopia
#9
Ruth Jackson, Fisaha Haile Tesfay, Tesfay Gebregzabher Gebrehiwot, Hagos Godefay
OBJECTIVES: To document factors that hinder or enable strategies to reduce the first and second delays of the Three Delays in rural and pastoralist areas in Ethiopia. METHODS: A key informant study was conducted with 44 Health Extension Workers in Afar Region, Kafa Zone (Southern Nation, Nationalities and Peoples' Region), and Adwa Woreda (Tigray Region). Health Extension Workers were trained to interview women and ask for stories about their recent experiences of birth...
November 25, 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27884665/airway-management-for-cesarean-delivery-performed-under-general-anesthesia
#10
S Rajagopalan, M Suresh, S L Clark, B Serratos, S Chandrasekhar
BACKGROUND: With the increasing popularity of neuraxial anesthesia, there has been a decline in the use of general anesthesia for cesarean delivery. We sought to examine the incidence, outcome and characteristics associated with a failed airway in patients undergoing cesarean delivery under general anesthesia. METHODS: A retrospective review of airway management in women undergoing cesarean delivery under general anesthesia over an eight-year period from 2006-2013 at an academic medical center was conducted...
October 27, 2016: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/27884029/-preclinical-birth-of-an-extremely-premature-infant-a-case-report
#11
Tobias Pöhlmann, Armin Schmidt, Wolfgang Pohl
Obstetrical emergencies requiring emergency medical service are very rare. An extremely premature birth in a preclinical setting is certainly exceptional. In the following case report, the emergency medical team was unexpectedly faced with the home birth of a fetus at the 23(rd) week of gestation. Prematurity at the edge of viability poses a challenge to first care, equipment, infrastructure, expertise and clinical ethics. To the authors' knowledge, there is no comparable case report published so far.
November 2016: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/27880069/role-of-first-trimester-hba1c-as-a-predictor-of-adverse-obstetric-outcomes-in-a-multi-ethnic-cohort
#12
Laura Mañé, Juana Antonia Flores-Le Roux, David Benaiges, Marta Rodríguez, Irene Marcelo, Juan José Chillarón, Juan Pedro-Botet, Gemma Llauradó, Lucía Gortazar, Ramón Carreras, Antonio Payà
CONTEXT: Risk of obstetric complications increases linearly with rising maternal glycaemia. Testing HbA1c is an effective option to detect hyperglycemia but its association with adverse pregnancy outcomes remains unclear. Emerging data sustains that an early HbA1c≥5.9% could act as a pregnancy risk marker. OBJECTIVE: To determine, in a multi-ethnic cohort, whether an early ≥5.9% HbA1c could be useful to identify women without diabetes mellitus at increased pregnancy risk...
November 23, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27871594/obstetric-team-simulation-program-challenges
#13
A S Bullough, S Wagner, T Boland, T P Waters, K Kim, W Adams
OBJECTIVE: To describe the challenges associated with the development and assessment of an obstetric emergency team simulation program. DESIGN: The goal was to develop a hybrid, in-situ and high fidelity obstetric emergency team simulation program that incorporated weekly simulation sessions on the labor and delivery unit, and quarterly, education protected sessions in the simulation center. All simulation sessions were video-recorded and reviewed. SETTING: Labor and delivery unit and simulation center...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27868456/emergency-peripartum-hysterectomy-single-center-ten-year-experience
#14
Hüseyin Çağlayan Özcan, Mete Gurol Uğur, Özcan Balat, Neslihan Bayramoğlu Tepe, Seyhun Sucu
PURPOSE: The purpose of our study is to determine the incidence, risk factors, indications, outcomes, and complications of emergency peripartum hysterectomy (EPH) performed in a university hospital. METHODS: This retrospective study includes 54 cases of EPH performed at the department of obstetrics and gynecology of Gaziantep University Hospital between the years 2005-2015. We included all hysterectomy cases during the first 24 h after delivery beyond 20 weeks of gestation...
December 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27865818/maternity-high-dependency-care-and-the-australian-midwife-a-review-of-the-literature
#15
Emma L Kingwell, Janice Butt, Gavin Leslie
BACKGROUND: Maternity high-dependency care has emerged throughout the 21st century in Australian maternity hospitals as a distinct sub-speciality of maternity care. However, what the care involves, how and why it should be provided, and the role of midwives in the provision of such care remains highly variable. INTRODUCTION: Rising levels of maternal morbidity from non-obstetric causes have led midwives to work with women who require highly complex care, beyond the standard customary midwifery role...
November 16, 2016: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/27863981/physician-s-perceived-roles-as-well-as-barriers-toward-caring-for-women-sex-assault-survivors
#16
Priyanka Amin, Raquel Buranosky, Judy C Chang
BACKGROUND: Sexual assault (SA) affects about 40% of women in the United States and has many mental and physical health sequelae. Physicians often do not address SA with patients, although SA survivors describe a desire to talk to physicians to obtain additional help. Little information exists on how providers perceive their roles regarding caring for women SA survivors and what barriers they face in providing this care. METHODS: We performed a qualitative study using semistructured one-on-one interviews with 16 faculty physicians from five specialties: obstetrics and gynecology (n = 4), internal medicine (n = 4), family medicine (n = 1), emergency medicine (n = 3), and psychiatry (n = 4)...
November 15, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/27863876/scoping-review-the-use-of-early-warning-systems-for-the-identification-of-in-hospital-patients-at-risk-of-deterioration
#17
REVIEW
Marie Danielle Le Lagadec, Trudy Dwyer
INTRODUCTION: Early warning systems (EWS) were developed as a means of alerting medical staff to patient clinical decline. Since 85% of severe adverse events are preceded by abnormal physiological signs, the patient bed-side vital signs observation chart has emerged as an EWS tool to help staff identify and quantify deteriorating patients. There are three broad categories of patient observation chart EWS: single or multiple parameter systems; aggregated weighted scoring systems; or combinations of single or multiple parameter and aggregated weighted scoring systems...
November 15, 2016: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/27856295/street-smarts-and-a-scalpel-emotional-intelligence-in-surgical-education
#18
Mary Kate Erdman, Alisha Bonaroti, Gina Provenzano, Rachel Appelbaum, Marybeth Browne
OBJECTIVE: To evaluate trends of emotional intelligence (EI) in surgical education and to compare the incorporation of EI in surgical education to other fields of graduate medical education. DESIGN: A MEDLINE search was performed for publications containing both "surgery" and "emotional intelligence" with at least one term present in the title. Articles were included if the authors deemed EI in surgical education to be a significant focus. A separate series of MEDLINE searches were performed with the phrase "emotional intelligence" in any field and either "surg*," "internal medicine," "pediatric," "neurology," "obstetric," "gynecology," "OBGYN," "emergency," or "psychiat*" in the title...
November 14, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27854496/parent-and-clinician-perspectives-on-sustained-behavior-change-after-a-prenatal-obesity-program-a-qualitative-study
#19
Emily F Gregory, Matthew A Goldshore, Nakiya N Showell, Marquita C Genies, Mariel E Harding, Janice L Henderson
BACKGROUND: Infants of obese women are at a high risk for development of obesity. Prenatal interventions targeting gestational weight gain among obese women have not demonstrated consistent benefits for infant growth trajectories. METHODS: To better understand why such programs may not influence infant growth, qualitative semi-structured interviews were conducted with 19 mothers who participated in a prenatal nutrition intervention for women with BMI 30 kg/m(2) or greater, and with 19 clinicians (13 pediatric, 6 obstetrical)...
November 17, 2016: Childhood Obesity
https://www.readbyqxmd.com/read/27853321/contextual-factors-influencing-the-implementation-of-the-obstetrics-hemorrhage-initiative-in-florida
#20
C A Vamos, E L Thompson, A Cantor, L Detman, E Bronson, A Phelps, J M Louis, A R Gregg, J S Curran, W Sappenfield
OBJECTIVE: The purpose of this study was to explore the multilevel contextual factors that influenced the implementation of the Obstetric Hemorrhage Initiative (OHI) among hospitals in Florida. STUDY DESIGN: A qualitative evaluation was conducted via in-depth interviews with multidisciplinary hospital staff (n=50) across 12 hospitals. Interviews were guided by the Consolidated Framework for Implementation Research and analyzed in Atlas.ti using rigorous qualitative analysis procedures...
November 17, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
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