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https://www.readbyqxmd.com/read/29325835/synthetic-mesh-vs-allograft-extensor-mechanism-reconstruction-in-total-knee-arthroplasty-a-systematic-review-of-the-literature-and-meta-analysis
#1
REVIEW
David Shau, Ryan Patton, Suhag Patel, Laura Ward, George Guild
BACKGROUND: Extensor mechanism disruption after total knee arthroplasty (TKA) is a devastating complication. Reconstruction with allograft and synthetic mesh has been described. However, these reports have typically been small case series, and controversy exists with regard to which reconstruction technique is optimal. METHODS: The authors performed a systematic review using PUBMED, MEDLINE, EMBASE, BIOSIS, Clinicaltrials.gov, and Cochrane Database of Systematic Reviews identifying 14 articles meeting inclusion criteria and producing 204 knees for comparison...
January 8, 2018: Knee
https://www.readbyqxmd.com/read/29325724/rheumatoid-arthritis-disease-modifying-agents-and-periprosthetic-joint-infection-what-does-a-joint-surgeon-need-to-know
#2
REVIEW
Mehrnoush H Yeganeh, Michael M Kheir, Alisina Shahi, Javad Parvizi
The incidence of periprosthetic joint infection (PJI) among patients with rheumatoid arthritis (RA) is 1.6× greater than in patients undergoing the same procedure for osteoarthritis. This higher risk "may" be due to the immunosuppressive therapies for RA patients including corticosteroids, such as prednisone, and disease-modifying antirheumatic drugs (DMARDs), such as methotrexate. There is a debate about the role of DMARDs in increasing the incidence of subsequent PJI. Studies show conflicting results, with some demonstrating no significant increase in the rates of PJI and some finding otherwise...
November 23, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29324934/stem-cells-therapy-the-future-in-the-management-of-systemic-sclerosis-a-case-report
#3
Jung In Song, Silvanie Volz, Maria Eirini Liodaki, Peter Mailänder, Konstantinos Kalousis
OBJECTIVE: Systemic sclerosis (SSc) is a connective tissue disorder of unknown etiology, with heterogeneous clinical manifestations and chronic and often progressive course. The diffuse cutaneous form of SSc (dcSSc) is characterized by thickening of the skin (scleroderma) and distinctive involvement of multiple internal organs. Patients with limited cutaneous SSc (lcSSc) generally have long-standing Raynaud's phenomenon before other manifestations of SSc appear. Over the last decade the Interest of adipose-derived cell therapy in regenerative medicine has increased continuously...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29316602/no-evidence-of-increased-infection-risk-with-forced-air-warming-devices-a-systematic-review
#4
Heather S Haeberle, Sergio M Navarro, Linsen T Samuel, Anton Khlopas, Assem A Sultan, Nipun Sodhi, Morad Chughtai, Michael A Mont, Prem N Ramkumar
INTRODUCTION: Forced-air warming devices have been reported to present a potential risk for surgical site infections (SSIs) and periprosthetic joint infections. Due to a lack of consensus, we reviewed the infection risk of forced-air warming devices. MATERIALS AND METHODS: A systematic literature review was performed, evaluating overall infection risk and bacterial load. A total of eight studies reporting outcomes from 1,965 subjects were included. RESULTS AND CONCLUSIONS: There is no current evidence in the orthopaedic literature that forced-air warming devices translate to increased SSIs...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29312848/season-of-the-year-influences-infection-rates-following-total-hip-arthroplasty
#5
Samuel Rosas, Alvin C Ong, Leonard T Buller, Karim G Sabeh, Tsun Yee Law, Martin W Roche, Victor H Hernandez
AIM: To research the influence of season of the year on periprosthetic joint infections. METHODS: We conducted a retrospective review of the entire Medicare files from 2005 to 2014. Seasons were classified as spring, summer, fall or winter. Regional variations were accounted for by dividing patients into four geographic regions as per the United States Census Bureau (Northeast, Midwest, West and South). Acute postoperative infection and deep periprosthetic infections within 90 d after surgery were tracked...
December 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/29311234/mycoplasma-bovis-induced-inhibition-of-bovine-pbmc-proliferation-is-ameliorated-after-blocking-the-immune-inhibitory-programmed-death-1-pd-1-receptor
#6
Muhammad Suleman, Farhan S Cyprian, Steve Jimbo, Teresia Maina, Tracy Prysliak, Claire Windeyer, Jose Perez-Casal
Mycoplasma bovis (M. bovis) induced-immune suppression is a major obstacle faced by the host for controlling infections. M. bovis impairment of antigen-specific T-cells responses is achieved through inhibiting the proliferation of peripheral-blood mononuclear cells (PBMC). This impairment may contribute to the persistence of M. bovis infection in various sites including lungs and its systemic spread to various organs like joints, with the underlying mechanisms remaining elusive. Here, we elucidated the role of the immune-inhibitory receptor programmed death-1 (PD-1) and its ligand (PD-L1) in M...
January 8, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29310922/are-all-periprosthetic-joint-infections-the-same-evaluating-major-vs-minor-criteria
#7
Mitchell R Klement, Ahmed Siddiqi, Justin M Rock, Thorsten M Seyler, Javad Parvizi, Antonia F Chen
BACKGROUND: The diagnosis of periprosthetic joint infection (PJI) can be made when 1 major criterion or 3 of 5 minor criteria are present. However, the outcomes of patients with a major vs minor criteria for diagnosis have not been studied. The objective of this study was to evaluate if a difference in outcome of surgical intervention existed between patients with PJI who were diagnosed with a major criterion or a combination of minor criteria. METHODS: A retrospective chart review identified 277 primary total hip or knee arthroplasty patients who had developed PJI based on the International Consensus Meeting definition...
December 14, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29310919/increased-complications-for-schizophrenia-and-bipolar-disorder-patients-undergoing-total-joint-arthroplasty
#8
Michael M Kheir, You Na P Kheir, Timothy L Tan, Colin T Ackerman, Alexander J Rondon, Antonia F Chen
BACKGROUND: Although it has been shown that anxiety and depression are associated with increased complications after total joint arthroplasty (TJA), the outcomes of TJA in patients with a history of psychosis are unknown. This study evaluated the influence of bipolar and schizophrenic disorders on complications after TJA, particularly aseptic and septic revisions. METHODS: A retrospective review of 156 TJAs (125 primaries and 31 revisions) was performed at a single institution from 2000 to 2015...
December 14, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29305460/delays-in-the-diagnosis-and-treatment-of-bone-and-joint-tuberculosis-in-the-united-kingdom
#9
C Broderick, S Hopkins, D J F Mack, W Aston, R Pollock, J A Skinner, S Warren
AIMS: Tuberculosis (TB) infection of bones and joints accounts for 6.7% of TB cases in England, and is associated with significant morbidity and disability. Public Health England reports that patients with TB experience delays in diagnosis and treatment. Our aims were to determine the demographics, presentation and investigation of patients with a TB infection of bones and joints, to help doctors assessing potential cases and to identify avoidable delays. PATIENTS AND METHODS: This was a retrospective observational study of all adults with positive TB cultures on specimens taken at a tertiary orthopaedic centre between June 2012 and May 2014...
January 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29305426/rapid-detection-of-periprosthetic-joint-infection-using-a-combination-of-16s-rdna-polymerase-chain-reaction-and-lateral-flow-immunoassay-a-pilot-study
#10
V Janz, J Schoon, C Morgenstern, B Preininger, S Reinke, G Duda, A Breitbach, C F Perka, S Geissler
OBJECTIVES: The objective of this study was to develop a test for the rapid (within 25 minutes) intraoperative detection of bacteria from synovial fluid to diagnose periprosthetic joint infection (PJI). METHODS: The 16s rDNA test combines a polymerase chain reaction (PCR) for amplification of 16s rDNA with a lateral flow immunoassay in one fully automated system. The synovial fluid of 77 patients undergoing joint aspiration or primary or revision total hip or knee surgery was prospectively collected...
January 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29298259/the-accuracy-of-the-alpha-defensin-lateral-flow-device-for-diagnosis-of-periprosthetic-joint-infection-comparison-with-a-gold-standard
#11
Thorsten Gehrke, Christian Lausmann, Mustafa Citak, Tommaso Bonanzinga, Lars Frommelt, Akos Zahar
BACKGROUND: Alpha defensin is a new biomarker that has been shown to have a very high accuracy to rule out periprosthetic joint infection. Recently, a new rapid lateral flow version of the alpha defensin test was developed and introduced to detect high levels of alpha defensin in synovial fluid quickly and with ease. We conducted a single-center prospective clinical study to compare the results of the Synovasure Alpha Defensin Test with those of the Musculoskeletal Infection Society (MSIS) criteria, which are considered to be the gold standard for diagnosing periprosthetic joint infection...
January 3, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29291158/antibiotic-prophylaxis-and-dair-treatment-in-primary-total-hip-and-knee-arthroplasty-a-national-survey-in-the-netherlands
#12
Ewout S Veltman, Dirk Jan F Moojen, Rob Ghh Nelissen, Rudolf W Poolman
BACKGROUND: To prevent postoperative infection the use of systemic antibiotic prophylaxis is common ground. Type of antibiotic used and duration of prophylaxis are subject to debate. In case of suspected early periprosthetic infection a debridement, antibiotics and implant retention (DAIR) procedure is treatment of first choice. This study evaluated the antibiotic prophylaxis and DAIR treatment protocols nationwide as well as reporting of these DAIR procedures to the national joint registry...
2018: Journal of Bone and Joint Infection
https://www.readbyqxmd.com/read/29290233/antibiotic-therapy-of-bone-and-joint-infections-in-children-proposals-of-the-french-pediatric-infectious-disease-group
#13
M Lorrot, Y Gillet, C Gras Le Guen, E Launay, R Cohen, E Grimprel
Acute hematogenous bone and joint infections (osteomyelitis, septic arthritis, osteoarthritis, and spondylodiscitis) affect more frequently children younger than 5 years of age. Early diagnosis and prompt treatment are needed to limit the risk of complications. Children with suspected bone and joint infections (BJI) should be hospitalized at the beginning of treatment. Surgical drainage is indicated in patients with septic arthritis and in those with periosteal abscess. Staphylococcus aureus is involved in BJIs in children at all ages; Kingella kingae is a very common causative pathogen in children under 4 years of age...
December 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29288184/leak-study-design-of-a-nationwide-randomised-controlled-trial-to-find-the-best-way-to-treat-wound-leakage-after-primary-hip-and-knee-arthroplasty
#14
Claudia A M Löwik, Frank-Christiaan Wagenaar, Walter van der Weegen, Rudolf W Poolman, Rob G H H Nelissen, Sjoerd K Bulstra, Yvette Pronk, Karin M Vermeulen, Marjan Wouthuyzen-Bakker, Inge van den Akker-Scheek, Martin Stevens, Paul C Jutte
INTRODUCTION: Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are highly successful treatment modalities for advanced osteoarthritis. However, prolonged wound leakage after arthroplasty is linked to prosthetic joint infection (PJI), which is a potentially devastating complication. On the one hand, wound leakage is reported as a risk factor for PJI with a leaking wound acting as a porte d'entrée for micro-organisms. On the other hand, prolonged wound leakage can be a symptom of PJI...
December 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/29286958/chronic-nocardia-cyriacigeorgica-periprosthetic-knee-infection-successfully-treated-with-a-two-stage-revision-a-case-report
#15
Michael M Hadeed, J Ryan MacDonell, Ian J Dempsey, Christopher C Moore, James A Browne
CASE: We report the successful treatment of a Nocardia cyriacigeorgica periprosthetic joint infection (PJI) that occurred at the site of a total knee arthroplasty. To our knowledge, this organism has not previously been reported in the literature as a cause of PJI. Given the need for a prolonged duration of treatment for this organism (a minimum of 6 to 12 months), modifications to the standard 2-stage revision were made in consultation with infectious-disease specialists. CONCLUSION: PJI is a devastating complication that leads to substantial patient morbidity and utilization of health-care resources...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29286032/-bidirectional-knotless-barbed-sutures-during-primary-total-knee-arthroplasty-effective-solution-or-new-problem
#16
D V Chugaev, N N Kornilov, S A Lasunskii
THE HYPOTHESIS OF THE STUDY: The use of bidirectional knotless barbed sutures for closure of capsule and subcutaneous fat tissue in primary total knee arthroplasty (TKA) is safe and time-saving. MATERIAL AND METHODS: 302 patients with end-stage osteoarthritis scheduled for primary non-complex TKA were randomly divided into two prospective groups: in group I (N=102) the capsule of the knee joint and subcutaneous fat tissues were closed by continuous braided suture while in group II (N=200) by bidirectional knotless barbed sutures...
2017: Khirurgiia
https://www.readbyqxmd.com/read/29281992/rapidly-growing-mycobacterial-infection-a-recognized-cause-of-early-onset-prosthetic-joint-infection
#17
Anupop Jitmuang, Varah Yuenyongviwat, Keerati Charoencholvanich, Methee Chayakulkeeree
BACKGROUND: Prosthetic joint infection (PJI) is a major complication of total hip and total knee arthroplasty (THA, TKA). Although mycobacteria are rarely the causative pathogens, it is important to recognize and treat them differently from non-mycobacterial infections. This study aimed to compare the clinical characteristics, associated factors and long-term outcomes of mycobacterial and non-mycobacterial PJI. METHODS: We conducted a retrospective case-control study of patients aged ≥18 years who were diagnosed with PJI of the hip or knee at Siriraj Hospital from January 2000 to December 2012...
December 28, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29277515/complications-with-cement-spacers-in-2-stage-treatment-of-periprosthetic-joint-infection-on-total-hip-replacement
#18
R Erivan, T Lecointe, G Villatte, A Mulliez, S Descamps, S Boisgard
INTRODUCTION: The aim of the present study was to assess our management of infected total hip replacement in indications for 2-stage surgical treatment according to current guidelines when a cement spacer has been used. The study hypothesis was that the complications rate related to cement spacers is low. MATERIAL AND METHOD: A single-center retrospective study included 26 patients receiving a spacer between the two stages of total hip replacement, over a 5 year period...
December 22, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29275901/complications-of-semiconstrained-distal-radioulnar-joint-arthroplasty
#19
Kate D Bellevue, Mary K Thayer, Michael Pouliot, Jerry I Huang, Douglas P Hanel
PURPOSE: The Aptis total distal radioulnar joint (DRUJ) prosthesis is a semiconstrained implant designed for treatment of DRUJ arthritis and instability. The purpose of this study was to analyze short-term complications of this device. METHODS: We performed a retrospective chart review of patients undergoing semiconstrained DRUJ arthroplasty from 2007 to 2015 at a single institution. Records were analyzed for complications and the need for subsequent surgical procedures...
December 22, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29275600/-effect-of-intermittent-negative-pressure-on-matrix-metalloproteinase-9-and-transforming-growth-factor-%C3%AE-of-tendon-bone-interface-and-joint-fluid-after-reconstruction-of-anterior-cruciate-ligament-in-rabbits
#20
Z M Sun, X H Dong, Z J Sun, Y H Chang, X Y Wu, Z Yi, M Ling
Objective: To study the effect of intermittent negative pressure on matrix metalloproteinase 9 (MMP)-9 and transforming growth factor β of tendon-bone interface and joint fluid after reconstruction of anterior cruciate ligament in rabbits. Methods: A total of twenty-four New Zealand white rabbits were randomly selected hind leg of negative group, contralateral hind leg as control.Reconstruction of the anterior cruciate ligament was done by autogenous semitendinosus of rabbit.Joint of the negative pressure side placed drainage tube connecting the micro-negative pressure aspirator, and maintained an intermittent, low-intensity negative pressure...
December 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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