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Maternal obesity

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https://www.readbyqxmd.com/read/29340906/an-exploratory-study-on-the-intergenerational-transmission-of-obesity-and-dieting-proneness
#1
Elizabeth A Claydon, Keith J Zullig, Christa L Lilly, Stephanie C Zerwas, Danielle M Davidov, Lesley Cottrell, Marney A White
PURPOSE: There is a paucity of research exploring individuals' memories of parental dieting behavior, engagement in "fat talk", or criticism of weight or eating behavior in childhood. This exploratory study utilized a community sample to further characterize the retrospective report of parenting dieting behavior. METHODS: A total of 507 participants (78.1% females; 20.7% males; and 1.2% transgender) were recruited to participate in an online, self-administered survey...
January 16, 2018: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29339565/a-home-visiting-parenting-program-and-child-obesity-a-randomized-trial
#2
Monica Roosa Ordway, Lois S Sadler, Margaret L Holland, Arietta Slade, Nancy Close, Linda C Mayes
BACKGROUND: Young children living in historically marginalized families are at risk for becoming adolescents with obesity and subsequently adults with increased obesity-related morbidities. These risks are particularly acute for Hispanic children. We hypothesized that the prevention-focused, socioecological approach of the "Minding the Baby" (MTB) home visiting program might decrease the rate of childhood overweight and obesity early in life. METHODS: This study is a prospective longitudinal cohort study in which we include data collected during 2 phases of the MTB randomized controlled trial...
January 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29338797/maternal-early-pregnancy-obesity-and-depressive-symptoms-during-and-after-pregnancy
#3
Satu M Kumpulainen, Polina Girchenko, Marius Lahti-Pulkkinen, Rebecca M Reynolds, Soile Tuovinen, Anu-Katriina Pesonen, Kati Heinonen, Eero Kajantie, Pia M Villa, Esa Hämäläinen, Hannele Laivuori, Katri Räikkönen
BACKGROUND: Previous studies have linked maternal obesity with depressive symptoms during and after pregnancy. It remains unknown whether obesity associates with consistently elevated depressive symptoms throughout pregnancy, predicts symptoms postpartum when accounting for antenatal symptoms, and if co-morbid hypertensive and diabetic disorders add to these associations. We addressed these questions in a sample of Finnish women whom we followed during and after pregnancy. METHODS: Early pregnancy body mass index, derived from the Finnish Medical Birth Register and hospital records in 3234 PREDO study participants, was categorized into underweight (<18...
January 17, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29337272/circulating-adipokines-and-mrna-expression-in-adipose-tissue-and-the-placenta-in-women-with-gestational-diabetes-mellitus
#4
Panayoula C Tsiotra, Panagiotis Halvatsiotis, Konstantinos Patsouras, Eirini Maratou, George Salamalekis, Sotirios A Raptis, George Dimitriadis, Eleni Boutati
Maternal adipose tissue and the placenta secrete various molecules commonly called adipokines such as chemerin, omentin-1, visfatin, adiponectin, and leptin that are important players in the pathogenesis of insulin resistance. Gestational diabetes mellitus (GDM) is defined as a state of glucose intolerance characterized by β-cell dysfunction and insulin resistance. To examine whether circulating adipokines and their mRNA expression in the adipose tissue and the placenta are altered in GDM pregnancy, we compared 15 GDM women [obese (BMI > 30) and non-obese (BMI < 30)] to 23 NGT (normal glucose tolerance) women [obese and non-obese], at the time of the Cesarean section...
January 11, 2018: Peptides
https://www.readbyqxmd.com/read/29336003/prevalence-of-pre-school-children-for-overweight-obesity-in-turkey
#5
Fatih Santas, Gulcan Santas
BACKGROUND: Most of the studies and interventions are targeted to address undernutrition, but childhood obesity has become a silent killer among children. Developing countries, including Turkey, could recognize the importance of the issue now and have begun to discuss the necessity of studies on this subject. Therefore, this study aims to examine the prevalence of obesity among pre-school children in Turkey. METHODS: The data source of this study is the Turkey Demographic and Health Survey (TDHS)-2013...
January 15, 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/29334717/-the-ten-year-retrospect-of-nutrition-and-health-status-of-pregnant-women-in-china
#6
C X Dong, S A Yin
Improvement of the nutrition and health status of pregnant women should be one of the top priority strategies of improving the physical fitness of next generation and reserve of talented person for national sustainable development. This paper reviews the nutrition and health status of pregnant women in China over the recent ten years and discusses the underlying factors and changing trends. The most popular nutrition-related problem is dietary imbalance, and many micronutrient intakes are lower than the recommended dietary intakes or adequate intakes, and some of nutrient intakes are still at a very low level for a long time such as vitamin D and calcium...
January 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29329330/obesity-and-abnormal-glucose-tolerance-in-offspring-of-diabetic-mothers-a-systematic-review-and-meta-analysis
#7
Maki Kawasaki, Naoko Arata, Celine Miyazaki, Rintaro Mori, Toru Kikuchi, Yoshihiro Ogawa, Erika Ota
BACKGROUND: Rising prevalence of childhood obesity and type 2 diabetes mellitus (T2DM) is an emerging public health issue. OBJECTIVES: To investigate the association of maternal hyperglycemia exposure during pregnancy with obesity and abnormal glucose tolerance in offspring, and the age at occurrence. METHODS: We searched MEDLINE and EMBASE for observational studies on obesity and diabetes in offspring of diabetic mothers (gestational diabetes mellitus (GDM), type 1 diabetes mellitus (T1DM) and T2DM), and those on non-diabetic mothers...
2018: PloS One
https://www.readbyqxmd.com/read/29329236/gender-associated-impact-of-early-leucine-supplementation-on-adult-predisposition-to-obesity-in-rats
#8
Nora López, Juana Sánchez, Andreu Palou, Francisca Serra
Early nutrition plays an important role in development and may constitute a relevant contributor to the onset of obesity in adulthood. The aim of this study was to evaluate the long-term impact of maternal leucine (Leu) supplementation during lactation on progeny in rats. A chow diet, supplemented with 2% Leu, was supplied during lactation (21 days) and, from weaning onwards, was replaced by a standard chow diet. Then, at adulthood (6 months of age), this was replaced with hypercaloric diets (either with high-fat (HF) or high-carbohydrate (HC) content), for two months, to induce obesity...
January 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29324697/association-between-fetal-adipokines-and-child-behavioral-problems-at-preschool-age-the-hokkaido-study-on-environment-and-children-s-health
#9
Machiko Minatoya, Sachiko Itoh, Atsuko Araki, Naomi Tamura, Keiko Yamazaki, Chihiro Miyashita, Reiko Kishi
Studies have suggested associations between maternal obesity and mental health problems of their children. However, the underlying mechanism is largely unknown. A possible mechanism can be via inflammatory states and the other possible mechanism is metabolic hormone-induced programming. Cross-talk between adipokines, including inflammatory cytokines and metabolic hormones secreted from adipose tissue and the central nervous system needs to be further investigated to elucidate the mechanism. Thus, the aim of this study was to investigate the association between fetal adipokine levels and child behavioral problems at preschool age...
January 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29324453/developmental-origins-of-health-span-and-life-span-a-mini-review
#10
Joshua D Preston, Leryn J Reynolds, Kevin J Pearson
BACKGROUND: A vast body of research has demonstrated that disease susceptibility and offspring health can be influenced by perinatal factors, which include both paternal and maternal behavior and environment. Offspring disease risk has the potential to affect the health span and life span of offspring. KEY FINDINGS: Various maternal factors, such as environmental toxicant exposure, diet, stress, exercise, age at conception, and longevity have the potential to influence age-associated diseases such as cardiovascular disease, obesity, diabetes, and cancer risk in offspring...
January 12, 2018: Gerontology
https://www.readbyqxmd.com/read/29324300/hippocampal-insulin-resistance-links-maternal-obesity-with-impaired-neuronal-plasticity-in-adult-offspring
#11
Lisa Schmitz, Rebecca Kuglin, Inga Bae-Gartz, Ruth Janoschek, Sarah Appel, Andrea Mesaros, Igor Jakovcevski, Christina Vohlen, Marion Handwerk, Regina Ensenauer, Jörg Dötsch, Eva Hucklenbruch-Rother
OBJECTIVE: Maternal obesity and a disturbed metabolic environment during pregnancy and lactation have been shown to result in many long-term health consequences for the offspring. Among them, impairments in neurocognitive development and performance belong to the most dreaded ones. So far, very few mechanistic approaches have aimed to determine the responsible molecular events. METHODS: In a mouse model of maternal diet-induced obesity and perinatal hyperinsulinemia, we assessed adult offspring's hippocampal insulin signaling as well as concurrent effects on markers of hippocampal neurogenesis, synaptic plasticity and function using western blotting and immunohistochemistry...
December 28, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29323940/elevated-blood-pressure-in-low-income-rural-preschool-children-is-associated-with-maternal-hypertension-during-pregnancy
#12
Paige Johnson, Michele Montgomery, Patrick Ewell
Hypertension (HTN) is a significant public health problem in adults, and rates of HTN are rising in children as well. The purpose of this study was to determine blood pressure (BP) and body mass index (BMI) levels in low-income, rural preschool children and investigate the relationship between child and maternal factors that impact BP and BMI in these children. Results indicated high rates of overweight/obesity and elevated BP levels in this sample. Maternal hypertension during pregnancy also emerged as a predictor of elevated BP in their children...
January 2018: Journal of Community Health Nursing
https://www.readbyqxmd.com/read/29321608/the-effect-of-maternal-vitamin-d-deficiency-during-pregnancy-on-body-fat-and-adipogenesis-in-rat-offspring
#13
Juan Wen, Qin Hong, Xingyun Wang, Lijun Zhu, Tianqi Wu, Pengfei Xu, Ziyi Fu, Lianghui You, Xing Wang, Chenbo Ji, Xirong Guo
To evaluate the effects of maternal vitamin D deficiency on body fat and adipogenesis in offspring rats, and explore the potential mechanism, we constructed a vitamin D deficient rat model and performed metabolic activity evaluation, body fat monitoring, biochemical analysis, adipogenesis assay, methylation microarray and RNA-seq for their offspring rats. We found the weight of vitamin D deficient (VDD) offspring was gradually higher than that of control (CLT) offspring, and the difference was significant since 10 weeks old...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29320992/caesarean-delivery-related-blood-transfusion-correlates-in-a-tertiary-hospital-in-southwest-nigeria
#14
Fatimat M Akinlusi, Kabiru A Rabiu, Idayat A Durojaiye, Adeniyi A Adewunmi, Tawaqualit A Ottun, Yusuf A Oshodi
BACKGROUND: Caesarean delivery carries a risk of major intra-operative blood loss and its performance is often delayed by non-availability of blood and blood products. Unnecessary cross-matching and reservation of blood lead to apparent scarcity in centres with limited supply. This study set out to identify the risk factors for blood transfusion in women who underwent caesarean delivery at a tertiary obstetric unit with a view to ensuring efficient blood utilization. METHODS: A prospective cohort analysis of 906 women who had caesarean deliveries at the Lagos State University Teaching Hospital, Nigeria between January and December, 2011...
January 10, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29319751/effects-of-maternal-high-fat-intake-during-pregnancy-and-lactation-on-total-cholesterol-and-adipose-tissue-in-neonatal-rats
#15
M S Lima, G S Perez, G L Morais, L S Santos, G S Cordeiro, R D Couto, T C B J Deiró, C G Leandro, J M Barreto-Medeiros
AIM: Obesity during pregnancy is one of the most established risk factors for negative long-term programming. The aim of the present study was to investigate the effects of maternal consumption of a high-fat diet during pregnancy and lactation on the weight gain, visceral adipose tissue and cholesterolemia in neonatal rats. METHODS: Wistar rats were divided into two groups according to the mother's diet during pregnancy and lactation: Control group (CG, n = 12) were the offspring of rats fed a standard diet (4% lipid) and the Test group (TG, n = 12) were pups rats fed on a high fat diet (23% lipid)...
January 8, 2018: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/29315988/impaired-treg-and-nk-cells-profile-in-overweight-women-with-gestational-diabetes-mellitus
#16
Thalita Frutuoso Lobo, Camila de Moraes Borges, Rosiane Mattar, Caio Perez Gomes, Ana Geisa Santos de Angelo, Karen Priscilla Tezotto Pendeloski, Silvia Daher
PROBLEM: Maternal obesity is frequently associated with gestational diabetes mellitus (GDM), and immunological mechanisms seem to be involved in the physiopathology of these conditions. The aim of this study was to characterize the profile of immune cells in peripheral blood of overweight women with GDM. METHOD OF STUDY: This case-control study included 27 glucose-tolerant (controls) and 31 GDM overweight pregnant women. Flow cytometry was used to assess the number of regulatory T cells (Treg) and natural killer (NK) cells in the peripheral blood...
January 5, 2018: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29315777/parental-education-and-family-income-affect-birth-weight-early-longitudinal-growth-and-body-mass-index-development-differently
#17
Rebecka Bramsved, Susann Regber, Daniel Novak, Kirsten Mehlig, Lauren Lissner, Staffan Mårild
AIM: This study investigated the effects of two parental socioeconomic characteristics, education and income, on the growth and obesity risks of children from birth to eight years of age. METHODS: Longitudinal growth data and national register-based information on socioeconomic characteristics were available for 3,030 Swedish children. The development of body mass index (BMI) and height were compared in groups dichotomised by parental education and income. RESULTS: Low parental education was associated with a higher BMI from four years of age, independent of income, immigrant background, maternal BMI and smoking during pregnancy...
January 7, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29311684/a-severely-short-statured-girl-with-47-xx-%C3%A2-%C3%A2-14-46-xx-upd-14-mat-mosaicism
#18
Kikumi Ushijima, Syuichi Yatsuga, Takako Matsumoto, Akie Nakamura, Maki Fukami, Masayo Kagami
The predominant symptoms of trisomy 14 mosaicism are prenatal and postnatal growth failure, ear abnormalities, congenital heart disease, developmental delay, and genitourinary abnormalities. Maternal uniparental disomy of chromosome 14 (upd(14)mat) presents discernible clinical features such as prenatal and postnatal growth failure, hypotonia, precocious puberty, and obesity. Given the small number of previously reported patients with a combination of trisomy 14 mosaicism and upd(14)mat, the detailed clinical features of these patients remain to be elucidated...
January 9, 2018: Journal of Human Genetics
https://www.readbyqxmd.com/read/29310617/exercise-training-during-pregnancy-reduces-circulating-insulin-levels-in-overweight-obese-women-postpartum-secondary-analysis-of-a-randomised-controlled-trial-the-etip-trial
#19
Kirsti K Garnæs, Siv Mørkved, Kjell Å Salvesen, Øyvind Salvesen, Trine Moholdt
BACKGROUND: The primary aim was to investigate if supervised exercise training during pregnancy could reduce postpartum weight retention (PPWR) three months after delivery in overweight and obese women. We also measured circulating markers of cardiometabolic health, body composition, blood pressure, and physical activity level. METHODS: This was a secondary analysis of a randomised controlled trial in which 91 women with BMI ≥ 28 kg/m2 were allocated 1:1 to an exercise program or a control group...
January 8, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29306622/commonly-occurring-adverse-birth-outcomes-and-maternal-depression-a-longitudinal-study
#20
A M Kingsbury, M Plotnikova, J M Najman
OBJECTIVES: Little is known about whether commonly occurring adverse birth outcomes have a long-term impact on the mental health of mothers. The aim of this study was to investigate whether commonly occurring adverse birth outcomes predicted mothers' depressive-symptom trajectories over a 27-year period following the birth of a baby. STUDY DESIGN: Longitudinal study. METHODS: Participants comprised a sub-group of women from the longitudinal cohort of the Mater and University of Queensland Study of Pregnancy...
January 4, 2018: Public Health
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