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JOURNAL ARTICLE
Emilie Gregers, Peter H Frederiksen, Nanna L J Udesen, Louise Linde, Ann Banke, Amalie L Povlsen, Jeppe P Larsen, Christian Hassager, Lisette O Jensen, Jens F Lassen, Henrik Schmidt, Hanne B Ravn, Peter M H Heegaard, Jacob E Møller
BACKGROUND: In selected cases of cardiogenic shock, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is combined with trans valvular micro axial flow pumps (ECMELLA). Observational studies indicate that ECMELLA may reduce mortality but exposing the patient to two advanced mechanical support devices may affect the early inflammatory response. We aimed to explore inflammatory biomarkers in a porcine cardiogenic shock model managed with V-A ECMO or ECMELLA. METHODS: Fourteen landrace pigs had acute myocardial infarction-induced cardiogenic shock with minimal arterial pulsatility by microsphere embolization and were afterwards managed 1:1 with either V-A ECMO or ECMELLA for 4 h...
April 22, 2024: Intensive Care Medicine Experimental
#2
John C Grotberg, Mary Sullivan, Rachel K McDonald, Vladimir Despotovic, Chad A Witt, Daniel Reynolds, Janet S Lee, Kunal Kotkar, Muhammad F Masood, Bryan D Kraft, Amit Pawale
No abstract text is available yet for this article.
April 22, 2024: Artificial Organs
#3
JOURNAL ARTICLE
Violette Suc, Julie Starck, Yael Levy, Yohan Soreze, Jerome Rambaud, Pierre-Louis Léger
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) is widely used for children treated for refractory respiratory failures or refractory cardiogenic shock. Its duration depends on organ functions recovery. Weaning is decided using macro-circulatory tools, but microcirculation is not well evaluated. Sidestream dark-field video imaging is used to assess the perfusion of the sublingual microvascular vessels. The aim of this study was to assess the predictive value of microcirculatory indices in ECMO weaning...
April 22, 2024: Artificial Organs
#4
JOURNAL ARTICLE
Kazuki Nomura, Ryotaro Inoue, Takahiro Narukawa, Masahiko Murakami, Tomotake Sekoguchi, Ryosai Inoue, Koji Hirano, Yasumi Maze, Toshiya Tokui, Teruhisa Kawaguchi
A 60-year old woman, sandwiched between two boats was brought to our hospital with severe respiratory failure. She was in pre-shock and there was extensive cutaneous emphysema from the face to abdomen. She required respirator support and bilateral chest tubes for hemopneumothorax. On the patient's 3rd hospital day, she received venovenous extracorporeal membrance oxgenation( ECMO) due to sudden ventilatory failure. The bronchofiberscopy revealed complete disruption of the left main bronchus and occlusion of the right one owing to blood clot and sputum...
April 2024: Kyobu Geka. the Japanese Journal of Thoracic Surgery
#5
JOURNAL ARTICLE
Kazuhisa Tanaka, Hidemi Suzuki, Ichiro Yoshino
BACKGROUND: Tracheobronchial injuries resulting from blunt trauma are relatively rare among chest injuries. However, if these injuries are not managed properly, they can be fatal. The prognosis is intricately linked to the precise diagnosis and treatment. We herein report three cases of tracheobronchial trauma that required surgical intervention. Case 1:A 17-year-old male sustained injuries when his torso became entangled in heavy machinery. The diagnosis revealed a tear in the right main bronchus, which required transportation with left single- lung ventilation...
April 2024: Kyobu Geka. the Japanese Journal of Thoracic Surgery
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JOURNAL ARTICLE
Eman Alazmi, Zahraa Akbar, Mariam Aldarweesh, Khalid Almuzayen, Eelaf Husain, Jehad Alharmi, Fatmah Alhadhoud
OBJECTIVES: COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2 virus). This virus evolved into several variants, each with different severity. There are surges in the numbers of infected patients, commonly described as "waves". In Kuwait, three waves occurred. Our study describes and compares the clinical presentation and outcomes of critically ill pregnant patients infected with different variants. METHODS: This was a retrospective cohort study in two intensive care units (ICU) dedicated to patients with COVID-19...
April 20, 2024: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
#7
JOURNAL ARTICLE
Maria Cristina Ruffa, Giacomo Bignante, Vittorio Bocciero, Sergio Fabbri, Dario Degl'Innocenti, Valentina Cauda, Gianluca Villa
Patients in intensive care are exposed to the risk of microparticle infusion via extracorporeal lines and the resulting complications. A possible source of microparticle release could be the extracorporeal circuit used in blood purification techniques, such as continuous renal replacement therapy (CRRT). Disposable components of CRRT circuits, such as replacement bags and circuit tubing, might release microparticles such as salt crystals produced by precipitation in replacement bags and plastic microparticles produced by spallation...
April 20, 2024: Scientific Reports
#8
JOURNAL ARTICLE
ZhaoMin Huang, Jiayi Zheng, Mingyang Wang, Shaoting Zeng, Miaoting Huang, Shuyi Peng, Jiajun Li, Jiaming Ji, Quan Chen, Xin Xu, Chao Yang, GuiLin Peng, Hanyu Yang
BACKGROUND: In lung transplantation (LTx) surgery, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can provide mechanical circulatory support to patients with cardiopulmonary failure. However, the use of heparin in the administration of ECMO can increase blood loss during LTx. This study aimed to evaluate the safety of heparin-free V-A ECMO strategies. METHODS: From September 2019 to April 2022, patients who underwent lung transplantation at the First Affiliated Hospital of Guangzhou Medical University were retrospectively reviewed...
April 20, 2024: Journal of Cardiothoracic Surgery
#9
JOURNAL ARTICLE
Sasa Rajsic, Benedikt Treml, Nicole Innerhofer, Christine Eckhardt, Aleksandra Radovanovic Spurnic, Robert Breitkopf
OBJECTIVE: The mismatch between the demand for and supply of organs for transplantation is steadily growing. Various strategies have been incorporated to improve the availability of organs, including organ use from patients receiving extracorporeal membrane oxygenation (ECMO) at the time of death. However, there is no systematic evidence of the outcome of grafts from these donors. DESIGN: Systematic literature review (Scopus and PubMed, up to October 11, 2023). SETTING: All study designs...
March 20, 2024: Journal of Cardiothoracic and Vascular Anesthesia
#10
Zhenhua Du, Yu-Hua Zhang, Liang Sun
No abstract text is available yet for this article.
March 13, 2024: Archivos de Bronconeumología
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Jose Alejandro Posso-Nuñez, Astrid Carolina Álvarez-Ortega, Diego Fernando Bautista-Rincón, Carlos Alejandro García-González, Indira Fabiana Cujiño-Álvarez, Álvaro Ignacio Sánchez-Ortiz, Mauricio Velásquez-Galvis
A 47-year-old male patient was referred to a level 1 trauma center with refractory acute respiratory distress syndrome, bilateral lung contusions, and flail chest after initial management for injuries sustained 5 days prior from an 8-m fall from a tower crane. Surgical stabilization of the rib fractures was achieved under extracorporeal membrane oxygenation support, with successful decannulation 4 days after surgery. The patient was discharged after 42 days and following multidisciplinary interventions...
June 2024: Trauma Case Reports
#12
JOURNAL ARTICLE
Li-Min Zhu, Chun-Xiang Li, Xiao-Lei Gong, Zhuo-Ming Xu, Jin-Long Liu, Hai-Bo Zhang
BACKGROUND: Plastic bronchitis (PB) can occur in patients who have undergone congenital heart surgery (CHS). This study aimed to investigate the clinical features of PB in children after CHS. METHODS: We conducted a retrospective cohort study using the electronic medical record system. The study population consisted of children diagnosed with PB after bronchoscopy in the cardiac intensive care unit after CHS from May 2016 to October 2021. RESULTS: A total of 68 children after CHS were finally included in the study (32 in the airway abnormalities group and 36 in the right ventricular dysfunction group)...
April 19, 2024: Italian Journal of Pediatrics
#13
JOURNAL ARTICLE
Clare E Ferguson, Kate Hayes, Oana A Tatucu-Babet, Kate J Lambell, Eldho Paul, Carol L Hodgson, Emma J Ridley
BACKGROUND: Adverse changes in muscle health (size and quality) are common in patients receiving extracorporeal membrane oxygenation (ECMO). Nutrition delivery may attenuate such changes, yet the relationship with muscle health remains poorly understood. This study explored the association between energy and protein delivery and changes in muscle health measured using ultrasound from baseline to day 10 and 20 in patients receiving ECMO. METHODS: A secondary analysis of data from a prospective study quantifying changes in muscle health using ultrasound in adults receiving ECMO was completed...
April 17, 2024: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
#14
JOURNAL ARTICLE
W F Shang, D C Chen
Prone positioning ventilation (PPV) is considered one of the essential therapeutic approaches in the management of acute respiratory distress syndrome (ARDS). Several randomized controlled clinical trials have demonstrated the efficacy of PPV in the treatment of patients with ARDS. However, it is not clear whether PPV treatment can reduce mortality in patients with veno-venous extracorporeal membrane oxygenation (VV-ECMO)-supported ARDS and corona virus disease 2019 (COVID-19)-associated ARDS. This review aims to discuss the known and unknown aspects of the mechanism of PPV for ARDS, the clinical efficacy of PPV for ARDS, VV-ECMO-supported ARDS, and COVID-19-related ARDS...
April 16, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
#15
JOURNAL ARTICLE
María V Fraga, Holly L Hedrick, Natalie E Rintoul, Yan Wang, Devon Ash, Sabrina J Flohr, Leny Mathew, Tom Reynolds, Jenny L Engelman, Catherine M Avitabile
OBJECTIVES: To describe the scope of left ventricular (LV) dysfunction and left heart hypoplasia (LHH) in infants with congenital diaphragmatic hernia (CDH), to determine associations with CDH severity, and to evaluate the odds of extracorporeal membrane oxygenation (ECMO) and death with categories of left heart disease. STUDY DESIGN: Demographic and clinical variables were collected from a single-center, retrospective cohort of CDH patients from January 2017 through May 2022...
April 16, 2024: Journal of Pediatrics
#16
JOURNAL ARTICLE
Carlotta Cacciatore, Mathilde Baudet, Estelle Jean, Simona Presente, Marylou Para, Romain Sonneville, Dimitri Arangalage, Nassim Ait Abdallah, Flore Sicre de Fontbrune, Pedro Henrique Prata, Benjamin Crichi, Baptiste Hervier, Nathalie Parquet, Gilles Soulat, Elie Mousseaux, Richard K Burt, Dominique Farge
Systemic sclerosis (SSc) is a rare autoimmune disease (AD), characterised by early diffuse vasculopathy, activation of the immune response and progressive skin and internal organ fibrosis. In severe progressive diffuse SSc (dSSc), autologous hematopoietic stem cell transplantation (aHSCT) improves survival, despite its own risk of complications and transplant related mortality (TRM). We present herein the case of a dSSc patient undergoing aHSCT with low dose cyclophosphamide conditioning and sudden acute myopericarditis and cardiogenic shock, four weeks after a second mRNA SARS-CoV-2 vaccine (Pfizer) injection...
April 9, 2024: Current Research in Translational Medicine
#17
JOURNAL ARTICLE
Laura D Zambrano, Margaret M Newhams, Regina M Simeone, Amanda B Payne, Michael Wu, Amber O Orzel-Lockwood, Natasha B Halasa, Jemima M Calixte, Pia S Pannaraj, Kanokporn Mongkolrattanothai, Julie A Boom, Leila C Sahni, Satoshi Kamidani, Kathleen Chiotos, Melissa A Cameron, Aline B Maddux, Katherine Irby, Jennifer E Schuster, Elizabeth H Mack, Austin Biggs, Bria M Coates, Kelly N Michelson, Katherine E Bline, Ryan A Nofziger, Hillary Crandall, Charlotte V Hobbs, Shira J Gertz, Sabrina M Heidemann, Tamara T Bradford, Tracie C Walker, Stephanie P Schwartz, Mary Allen Staat, Samina S Bhumbra, Janet R Hume, Michele Kong, Melissa S Stockwell, Thomas J Connors, Melissa L Cullimore, Heidi R Flori, Emily R Levy, Natalie Z Cvijanovich, Matt S Zinter, Mia Maamari, Cindy Bowens, Danielle M Zerr, Judith A Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph
Pediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#18
JOURNAL ARTICLE
Dariusz Zieliński, Szymon Darocha, Arkadiusz Pietrasik, Michał Machowski, Krzysztof Wróbel, Marcin Kurzyna, Piotr Pruszczyk, Adam Torbicki, Andrzej Biederman
BACKGROUND: This study aimed to assess the prevalence of chronic thromboembolic lesions in the pulmonary arteries among patients undergoing pulmonary embolectomy for acute pulmonary embolism and their impact on treatment outcomes. METHODS: We conducted a retrospective, single-center analysis of consecutive patients undergoing emergency pulmonary embolectomy for acute pulmonary embolism between 2013 and August 2021. According to European Society of Cardiology guidelines, the diagnosis was based on clinical presentation, imaging studies and laboratory tests...
April 18, 2024: Journal of Cardiovascular Surgery
#19
JOURNAL ARTICLE
Jeffrey Balian, Saad Mallick, Nguyen Le, Giselle Porter, Amulya Vadlakonda, Konmal Ali, Elsa Kronen, Peyman Benharash
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) has emerged as a life-sustaining measure for individuals with end-stage cardiopulmonary derangements. An estimated one-third of patients must be transferred to a specialized center to receive this intervention. Therefore, the present study sought to characterize the impact of interhospital transfer (IHT) status on outcomes following ECMO. METHODS: The 2016-2020 National Inpatient Sample was queried to identify all adult (≥18 years) hospitalizations for ECMO...
April 18, 2024: American Surgeon
#20
JOURNAL ARTICLE
Bhoumesh Patel, Ahmed S Said, Angelo Justus, Darryl Abrams, Tái Pham, Marta Velia Antonini, Elizabeth Moore, Kiran Shekar, Bishoy Zakhary
BACKGROUND: The use of extracorporeal membrane oxygenation (ECMO) has grown rapidly over the past decades because of evolving indications, advances in circuit technology, and encouraging results from modern trials. Because ECMO is a complex and highly invasive therapy that requires a multidisciplinary team, optimal education, training, and credentialing remain a challenge. OBJECTIVE: The primary objectives of this study were to investigate the prevalence and application of ECMO education and ECMO practitioner credentialing at ECMO centers globally...
March 2024: ATS scholar
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