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https://www.readbyqxmd.com/read/28531917/assessing-phytotoxicity-of-trace-element-contaminated-soils-phytomanaged-with-gentle-remediation-options-at-ten-european-field-trials
#1
Celestino Quintela-Sabarís, Lilian Marchand, Petra S Kidd, Wolfgang Friesl-Hanl, Markus Puschenreiter, Jurate Kumpiene, Ingo Müller, Silke Neu, Jolien Janssen, Jaco Vangronsveld, Ioannis Dimitriou, Grzegorz Siebielec, Rafał Gałązka, Valérie Bert, Rolf Herzig, Andrew B Cundy, Nadège Oustrière, Aliaksandr Kolbas, William Galland, Michel Mench
Gentle remediation options (GRO), i.e. in situ stabilisation, (aided) phytoextraction and (aided) phytostabilisation, were implemented at ten European sites contaminated with trace elements (TE) from various anthropogenic sources: mining, atmospheric fallout, landfill leachates, wood preservatives, dredged-sediments, and dumped wastes. To assess the performance of the GRO options, topsoil was collected from each field trial, potted, and cultivated with lettuce (Lactuca sativa L.) for 48days. Shoot dry weight (DW) yield, photosynthesis efficiency and major element and TE concentrations in the soil pore water and lettuce shoots were measured...
May 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28531295/right-ventricular-vascular-coupling-in-heart-failure-with-preserved-ejection-fraction-and-pre-vs-post-capillary-pulmonary-hypertension
#2
Thomas M Gorter, Dirk J van Veldhuisen, Adriaan A Voors, Yoran M Hummel, Carolyn S P Lam, Rolf M F Berger, Joost P van Melle, Elke S Hoendermis
Aims: Many patients with heart failure with preserved ejection fraction (HFpEF) develop post-capillary pulmonary hypertension (PH) due to increased left-sided filling pressures. However, a subset of patients develops combined post- and pre-capillary PH. We studied the value of echocardiographic right-sided characterization for the discrimination between pre- vs. post-capillary PH in HFpEF, using invasive haemodynamics as gold standard. Methods and results: 102 consecutive HFpEF patients with simultaneous right heart catheterization and echocardiography were identified...
May 22, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28530292/soil-sorption-of-two-nitramines-derived-from-amine-based-co2-capture
#3
Cathrine Brecke Gundersen, Gijs D Breedveld, Lena Foseid, Rolf D Vogt
Nitramines are potentially carcinogens that form from the amines used in post-combustion CO2 capture (PCCC). The soil sorption characteristics of monoethanol (MEA)- and dimethyl (DMA)-nitramines have been assessed using a batch experimental setup, and defined indirectly by measuring loss of nitramine (LC-MS/MS) from the aqueous phase (0.01 M CaCl2 and 0.1% NaN3) after equilibrium had been established with the soil (24 h). Nitramine soil sorption was found to be strongly dependent on the content of organic matter in the soil (r(2) = 0...
May 22, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28529910/generalizable-items-of-quantitative-and-qualitative-cornerstones-for-personnel-requirement-of-physicians-in-anesthesia
#4
REVIEW
Manfred Weiss, Rolf Rossaint, Thomas Iber
Anesthesiologists perform a broad spectrum of tasks. However, in many countries, there is no legal basis for personnel staffing of physicians in anesthesia. Also, the German diagnosis related groups system for refunding does not deliver such a basis. Thus, in 2006 a new calculation base for the personnel requirement that included an Excel calculation sheet was introduced by the German Board of Anesthesiologists (BDA) and the German Society of Anesthesiology and Intensive Care Medicine (DGAI), and updated in 2009 and 2015...
May 4, 2017: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/28528549/analysis-of-the-148-gd-and-154-dy-content-in-proton-irradiated-lead-targets
#5
Zeynep Talip, Sara Pfister, Rugard Dressler, Jean-Christophe David, Alexander Voegele, Peter Vontobel, Rolf Michel, Dorothea Schumann
This work presents the determination of the (148)Gd and (154)Dy content in Pb targets, irradiated by 220 MeV-2600 MeV protons. It includes the chemical separation of lanthanides, followed by the preparation of proper samples, by molecular plating technique, for α-spectrometry measurements. The experimental cross section results were compared with theoretical predictions, calculated with the INCL++-ABLA07 code. The comparisons showed a satisfactory agreement for (148)Gd (less than within a factor two), while measured (154)Dy cross sections are higher than the theoretical values...
May 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28527546/-keeping-them-warm-a-randomized-controlled-trial-of-two-passive-perioperative-warming-methods
#6
Michael Koenen, Megan Passey, Margaret Rolfe
PURPOSE: Inadvertent perioperative hypothermia is a common problem for patients undergoing surgery. Heat redistribution from the body's core to the periphery after induction of anesthesia is the major contributor. DESIGN: A prospective randomized controlled trial was conducted to determine if reflective blankets are more effective than cotton blankets in reducing the core-peripheral temperature gradient and increasing peripheral compartment heat content during the preoperative phase among adult patients undergoing elective surgery of less than 1 hour...
June 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28525538/chimeraviz-a-tool-for-visualizing-chimeric-rna
#7
Stian Lågstad, Sen Zhao, Andreas M Hoff, Bjarne Johannessen, Ole Christian Lingjærde, Rolf I Skotheim
Summary: Advances in high-throughput RNA sequencing have enabled more efficient detection of fusion transcripts, but the technology and associated software used for fusion detection from sequencing data often yield a high false discovery rate. Good prioritization of the results is important, and this can be helped by a visualization framework that automatically integrates RNA data with known genomic features. Here we present chimeraviz , a Bioconductor package that automates the creation of chimeric RNA visualizations...
May 19, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28523698/survey-among-critical-care-nurses-and-physicians-about-delirium-management
#8
Peter Nydahl, Michael Dewes, Rolf Dubb, Carsten Hermes, Arnold Kaltwasser, Susanne Krotsetis, Rebecca von Haken
BACKGROUND: Delirium is a serious complication in patients in intensive care units. Previous surveys on delirium management in daily practice showed low adherence to published guidelines. AIM: To evaluate delirium management in nurses and physicians working in intensive care units in German-speaking countries and to identify related differences between nurses and physicians. DESIGN: The study used an open online survey with multiple-choice responses...
May 18, 2017: Nursing in Critical Care
https://www.readbyqxmd.com/read/28523471/quantification-of-left-atrial-volume-and-phasic-function-using-cardiovascular-magnetic-resonance-imaging-comparison-of-biplane-area-length-method-and-simpson-s-method
#9
Laura Kristin Wandelt, Johannes Tammo Kowallick, Andreas Schuster, Rolf Wachter, Thomas Stümpfig, Christina Unterberg-Buchwald, Michael Steinmetz, Christian Oliver Ritter, Joachim Lotz, Wieland Staab
Left atrial (LA) enlargement and dysfunction are markers of chronic diastolic dysfunction and an important predictor of adverse cardiovascular and cerebrovascular outcomes. Accordingly, accurate quantification of left atrial volume (LAV) and function is needed. In routine clinical cardiovascular magnetic resonance (CMR) imaging the biplane area-length method (Bi-ALM) is frequently applied due to time-saving image acquisition and analysis. However, given the varying anatomy of the LA we hypothesized that the diagnostic accuracy of the Bi-ALM is not sufficient and that results would be different from a precise volumetric assessment of transversal multi-slice cine images using Simpson's method...
May 18, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28522721/first-insights-into-the-genome-sequence-of-the-alkaliphilic-thermotolerant-bacterium-clostridium-thermoalcaliphilum-jw-yl23-2-t
#10
Anja Poehlein, Alexandra Berg, Gina Welsing, Rolf Daniel
Clostridium thermoalcaliphilum is an obligate anaerobic and rod-shaped bacterium isolated from sewage sludge. It is an alkaliphilic thermotolerant organism and utilizes sucrose, glucose, fructose, maltose, cellobiose, amino acids, and Casamino Acids as substrates. The draft genome comprises 2.031 Mbp and 2,027 predicted protein-coding genes.
May 18, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28522720/first-insight-into-the-genome-sequence-of-clostridium-thermobutyricum-dsm-4928-a-butyrate-producing-moderate-thermophile
#11
Anja Poehlein, Abirami Anbalagan, Alexandra Nagel, Rolf Daniel
The moderately thermophilic and Gram-positive bacterium Clostridium thermobutyricum is strictly anaerobic and forms subterminally located endospores. It was isolated from horse manure compost. C. thermobutyricum produces butyrate as the main fermentation product. The draft genome consists of one circular chromosome (3.425 Mb) and contains 3,201 predicted protein-coding genes.
May 18, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28522716/first-insights-into-the-genome-sequence-of-the-cellulolytic-bacterium-clostridium-hungatei-dsm-14427
#12
Anja Poehlein, Katrina Funkner, Miriam A Schüler, Rolf Daniel
Clostridium hungatei is an obligate anaerobic and spore-forming bacterium, which was isolated from soil. It ferments carbohydrates, such as cellulose or d-glucose. C. hungatei is able to fix nitrogen. The draft genome consists of 1 chromosome (4.902 Mb) with 4,246 predicted protein-coding genes.
May 18, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28516519/exercise-training-in-diastolic-heart-failure-ex-dhf-rationale-and-design-of-a-multicentre-prospective-randomized-controlled-parallel-group-trial
#13
Frank Edelmann, Anna Bobenko, Götz Gelbrich, Gerd Hasenfuss, Christoph Herrmann-Lingen, André Duvinage, Silja Schwarz, Meinhard Mende, Christiane Prettin, Tobias Trippel, Ruhdja Lindhorst, Daniel Morris, Elisabeth Pieske-Kraigher, Kathleen Nolte, Hans-Dirk Düngen, Rolf Wachter, Martin Halle, Burkert Pieske
Heart failure with preserved ejection fraction (HFpEF) is a common disease with high incidence and increasing prevalence. Patients suffer from functional limitation, poor health-related quality of life, and reduced prognosis. A pilot study in a smaller group of HFpEF patients showed that structured, supervised exercise training (ET) improves maximal exercise capacity, diastolic function, and physical quality of life. However, the long-term effects of ET on patient-related outcomes remain unclear in HFpEF. The primary objective of the Exercise training in Diastolic Heart Failure (Ex-DHF) trial is to investigate whether a 12 month supervised ET can improve a clinically meaningful composite outcome score in HFpEF patients...
May 17, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28514816/-novel-thixotropic-silicone-oils-the-ketchup-bottle-approach-for-silicone-oil-endotamponades
#14
Christian Klameth, Berenike Kunzmann, Maximilian Schultheiß, Rolf Daniels, Nelli Klameth, Martin Spitzer
Silicone oil endotamponades need to be injected and removed in a reasonable time and under moderate pressure conditions. However, due to ever-decreasing sizes of incisions and trocars, injection and removal of highly viscous silicone oils is very time-consuming. To address resulting problems like longer treatment times or hypotony, thixotropic silicone oils were developed. These oils are characterized by a diminished viscosity under constant mechanical stress; whilst there is pressure or vacuum acting on it, the oils will become more fluid and, therefore, much easier to be applied...
May 17, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28513746/structure-functionality-relationship-and-pharmacological-profiles-of-pseudomonas-aeruginosa-alkylquinolone-quorum-sensing-modulators
#15
Ahmed A M Kamal, Lucia Petrera, Jens Eberhard, Rolf W Hartmann
An important paradigm in anti-infective research is the antivirulence concept. Pathoblockers are compounds which disarm bacteria of their arsenal of virulence factors. PqsR is a transcriptional regulator controlling the production of such factors in Pseudomonas aeruginosa, most prominently pyocyanin. In this work, a series of tool compounds based on the structure of the natural ligand 2-heptyl-4-quinolone (HHQ) were used for probing the structure-functionality relationship. Four different profiles are identified namely agonists, antagonists, inverse agonists and biphasic modulators...
May 17, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28512434/evaluation-of-a-rapid-anisotropic-model-for-ecg-simulation
#16
Simone Pezzuto, Peter Kal'avský, Mark Potse, Frits W Prinzen, Angelo Auricchio, Rolf Krause
State-of-the-art cardiac electrophysiology models that are able to deliver physiologically motivated activation maps and electrocardiograms (ECGs) can only be solved on high-performance computing architectures. This makes it nearly impossible to adopt such models in clinical practice. ECG imaging tools typically rely on simplified models, but these neglect the anisotropic electric conductivity of the tissue in the forward problem. Moreover, their results are often confined to the heart-torso interface. We propose a forward model that fully accounts for the anisotropic tissue conductivity and produces the standard 12-lead ECG in a few seconds...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28511231/-epididymitis-in-children-fact-or-fiction
#17
Rolf Beetz, Maximilian Stehr
Epididymitis is one of the most frequent causes of acute scrotum during childhood. Unlike in adults, ascending bacterial infections are rarely the underlying cause of the condition in children. Antibacterial treatment in accordance with a prior antibiogram is possible in the presence of leukocyturia and significant bacteriuria. For the remaining cases, there are no definite criteria allowing for a decision on acute antibacterial treatment. The fact that antibacterial treatment is still initiated in cases of epididymitis in the clinical routine setting is based on the assumption of a possible infection rather than being based on facts...
May 16, 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28511011/iron-hydroperoxide-intermediate-in-superoxide-reductase-protonation-or-dissociation-first-mm-dynamics-and-qm-mm-metadynamics-study
#18
Rolf David, Helene Jamet, Vincent Niviere, Yohann Moreau, Anne Milet
Superoxide reductase is a mononuclear iron enzyme involved in superoxide radical detoxification in some bacteria. Its catalytic mechanism is associated with the remarkable formation of a ferric hydroperoxide Fe3+-OOH intermediate, which is specifically protonated on its proximal oxygen to generate the reaction product H2O2. Here we present a computational study of the protonation mechanism of the Fe3+ OOH intermediate, at different level of theory. This was performed on the whole system (solvated protein) using well-tempered metadynamics at the QM/MM (B3LYP/AmberFF99SB) level...
May 16, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28508504/aiba-aibb-induces-an-intramolecular-decarboxylation-in-isovalerate-biosynthesis-by-myxococcus-xanthus
#19
Tobias Bock, Eva Luxenburger, Judith Hoffmann, Vlad Schütza, Christian Feiler, Rolf Müller, Wulf Blankenfeldt
Isovaleryl coenzyme A (IV-CoA) is an important precursor for iso-fatty acids and lipids. It acts in the development of myxobacteria, which can produce this compound from acetyl-CoA through alternative IV-CoA biosynthesis (aib). A central reaction of aib is catalyzed by AibA/AibB, which acts as a cofactor-free decarboxylase despite belonging to the family of CoA-transferases. We developed an efficient expression system for AibA/AibB that allowed the determination of high-resolution crystal structures in complex with different ligands...
May 16, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28507745/performance-measures-for-lower-gastrointestinal-endoscopy-a-european-society-of-gastrointestinal-endoscopy-esge-quality-improvement-initiative
#20
REVIEW
Michal F Kaminski, Siwan Thomas-Gibson, Marek Bugajski, Michael Bretthauer, Colin J Rees, Evelien Dekker, Geir Hoff, Rodrigo Jover, Stepan Suchanek, Monika Ferlitsch, John Anderson, Thomas Roesch, Rolf Hultcranz, Istvan Racz, Ernst J Kuipers, Kjetil Garborg, James E East, Maciej Rupinski, Birgitte Seip, Cathy Bennett, Carlo Senore, Silvia Minozzi, Raf Bisschops, Dirk Domagk, Roland Valori, Cristiano Spada, Cesare Hassan, Mario Dinis-Ribeiro, Matthew D Rutter
The European Society of Gastrointestinal Endoscopy and United European Gastroenterology present a short list of key performance measures for lower gastrointestinal endoscopy. We recommend that endoscopy services across Europe adopt the following seven key performance measures for lower gastrointestinal endoscopy for measurement and evaluation in daily practice at a center and endoscopist level: 1 rate of adequate bowel preparation (minimum standard 90%); 2 cecal intubation rate (minimum standard 90%); 3 adenoma detection rate (minimum standard 25%); 4 appropriate polypectomy technique (minimum standard 80%); 5 complication rate (minimum standard not set); 6 patient experience (minimum standard not set); 7 appropriate post-polypectomy surveillance recommendations (minimum standard not set)...
April 2017: United European Gastroenterology Journal
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