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https://www.readbyqxmd.com/read/29141263/cross-correlation-of-heart-rate-and-oxygen-saturation-in-very-low-birthweight-infants-association-with-apnea-and-adverse-events
#1
Karen D Fairchild, Douglas E Lake
No abstract text is available yet for this article.
November 15, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29136344/the-hypoxic-test-in-preterm-neonates-reinvestigated
#2
Christelle Kouakam, Erwan Stephan-Blanchard, André Léké, Guy Kongolo, Elodie Haraux, Stéphane Delanaud, Frédéric Telliez, Karen Chardon
AIM: We currently lack a suitable gold-standard method for implementation on modern equipment to assess peripheral chemoreceptor sensitivity. The aim of the present study was to develop an accurate and reproducible method for assessing peripheral chemoreceptors sensitivity in sleeping preterm neonates. METHODS: A poïkilocapnic hypoxic test was performed twice during rapid eye movement sleep (REM sleep) and non-rapid eye movement sleep (nonREM sleep). The infant breathed hypoxic gas (15% O2 ) for 60 s...
November 14, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29120450/apnea-bradycardia-and-desaturation-spells-in-premature-infants-impact-of-a-protocol-for-the-duration-of-spell-free-observation-on-interprovider-variability-and-readmission-rates
#3
P Chandrasekharan, M Rawat, A M Reynolds, K Phillips, S Lakshminrusimha
OBJECTIVE: To study the impact of implementing a protocol to standardize the duration of observation in preterm infants with apnea/bradycardia/desaturation spells before hospital discharge on length of stay (LOS) and readmission rates. STUDY DESIGN: A protocol to standardize the duration of in-hospital observation for preterm infants with apnea, bradycardia and desaturation spells who were otherwise ready for discharge was implemented in December 2013. We evaluated the impact of this protocol on the LOS and readmission rates of very low birth weight infants (VLBW)...
November 9, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29110581/outcomes-of-drug-induced-sleep-endoscopy-directed-surgery-for-pediatric-obstructive-sleep-apnea
#4
Shan He, Nithin S Peddireddy, David F Smith, Angela L Duggins, Christine Heubi, Sally R Shott, Stacey L Ishman
Objectives To determine the effectiveness of pediatric drug-induced sleep endoscopy (DISE)-directed surgery for children with infant obstructive sleep apnea (OSA) or OSA after adenotonsillectomy. Study Design Case series with chart review. Setting Tertiary care pediatric hospital. Subjects and Methods We included 56 children undergoing DISE from October 2013 to September 2015 who underwent subsequent surgery to address OSA. The primary outcome was successful response to DISE-directed surgery based on the postoperative obstructive Apnea-Hypopnea Index (oAHI)...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29099422/the-endoscopic-and-histologic-findings-of-infants-who-have-experienced-brief-resolved-unexplained-events
#5
Chaowapong Jarasvaraparn, Maria B R Gallegos, Madhuri S Mulekar, Bin Wang, David A Gremse, Karen D Crissinger
INTRODUCTION: A brief resolved unexplained event (BRUE) describes an event associated with a change in muscle tone, color, respiration, and responsiveness that is unexplained after an appropriate examination. Some infants with higher risk BRUE may undergo endoscopy as part of their evaluation. OBJECTIVE: This retrospective study aimed to identify the endoscopic findings in infants who have experienced a higher risk BRUE. We also compared the characteristics, prenatal, natal, and postnatal risk factors between 23 infants who underwent endoscopic evaluation and 23 race-matched/sex-matched/term-matched/preterm-matched infants who did not undergo endoscopic evaluation...
November 2, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29081031/drug-induced-sedation-endoscopy-in-surgically-na%C3%A3-ve-infants-and-children-with-obstructive-sleep-apnea-impact-on-treatment-decision-and-outcome
#6
A Boudewyns, V Saldien, P Van de Heyning, S Verhulst
PURPOSE: Adenotonsillectomy (AT) is the first-line treatment for obstructive sleep apnea (OSA) in children irrespective of clinical upper airway (UA) findings. We aimed to investigate whether drug-induced sedation endoscopy (DISE) changes treatment decision and outcome in otherwise healthy children and infants with OSA. METHODS: Retrospective analysis of prospectively collected data on polysomnography, DISE, and treatment in surgically naïve, otherwise healthy infants (n = 34) and children (n = 75) with OSA...
October 28, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29068938/pediatric-obstructive-sleep-apnea-consensus-controversy-and-craniofacial-considerations
#7
REVIEW
Ravi K Garg, Ahmed M Afifi, Catharine B Garland, Ruston Sanchez, Delora L Mount
Pediatric obstructive sleep apnea, characterized by partial or complete obstruction of the upper airway during sleep, is associated with multiple adverse neurodevelopmental and cardiometabolic consequences. It is common in healthy children and occurs with a higher incidence among infants and children with craniofacial anomalies. Although soft-tissue hypertrophy is the most common cause, interplay between soft tissue and bone structure in children with craniofacial differences may also contribute to upper airway obstruction...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29065963/neurodevelopmental-outcomes-at-two-years-of-age-for-premature-infants-diagnosed-with-neonatal-obstructive-sleep-apnea
#8
Sean Deering, Lin Liu, Tania Zamora, Joanne Hamilton, Carl Stepnowsky
STUDY OBJECTIVES: Neurocognitive deficits have been shown in school-aged children with sleep apnea. The effect of obstructive sleep apnea (OSA) on the neurodevelopmental outcome of preterm infants is unknown. METHODS: A retrospective chart review was performed for all preterm infants (< 37 weeks) who had neonatal polysomnography (PSG) and completed neurodevelopmental assessment with the Bayley Scales of Infant and Toddler Development, 3rd Edition, between 2006 to 2015 at Riley Hospital...
October 18, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29064170/sleep-disordered-breathing-in-bronchopulmonary-dysplasia
#9
Luis E Ortiz, Sharon A McGrath-Morrow, Laura M Sterni, Joseph M Collaco
BACKGROUND: There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the development of SDB. METHODS: This is a retrospective study of patient factors and overnight polysomnogram (PSG) data of children enrolled in our BPD registry between 2008 and 2015...
October 24, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29046872/swallow-breath-interaction-and-phase-of-respiration-with-swallow-during-non-nutritive-suck-in-infants-affected-by-neonatal-abstinence-syndrome
#10
Eric W Reynolds, Debbie Grider, Cynthia S Bell
BACKGROUND: The development of suck-swallow-breath rhythms during non-nutritive suck (NNS) may be an indicator of neurologic integrity. We have described swallow-breath (SwBr) interaction and phase of respiration (POR) with swallow during NNS in low-risk preterm (LRP) infants. NNS in infants with neonatal abstinence syndrome (NAS) has not been described with our method. METHOD: Suckle, swallow, thoracic motion, and nasal airflow were measured during NNS in 10 infants with NAS and 12 unaffected infants (control)...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29029347/childhood-health-and-educational-outcomes-associated-with-maternal-sleep-apnea-a-population-record-linkage-study
#11
Yu Sun Bin, Peter A Cistulli, Christine L Roberts, Jane B Ford
Objectives: Sleep apnea in pregnancy is known to adversely affect birth outcomes. Whether in utero exposure to maternal sleep apnea is associated with long-term childhood consequences is unclear. Methods: Population-based longitudinal study of singleton infants born during 2002 to 2012 was conducted using linked birth, hospital, death, developmental, and educational records from New South Wales, Australia. Maternal sleep apnea during pregnancy was identified from hospital records...
October 5, 2017: Sleep
https://www.readbyqxmd.com/read/29023804/apnea-induction-for-invasive-lung-function-testing-in-infant-olive-baboons-comparison-of-intravenous-propofol-versus-hyperventilation
#12
Vadim A Ivanov, Roman F Wolf, James F Papin, Michael P Anderson, Claude L Hill, Robert C Welliver
BACKGROUND: In various types of pulmonary research, pulmonary function testing (PFT) is performed to quantify the severity of lung disease. Induction of apnea and positive pressure ventilation are required for accurate PFT measurements in non-cooperative subjects. We compared two methods of apnea induction in infant olive baboons (Papio anubis). METHODS: Pulmonary function testing results were compared during apnea induced by hyperventilation (CO2 washout) vs. intravenous propofol (1 dose 10 mg/kg)...
October 12, 2017: Journal of Medical Primatology
https://www.readbyqxmd.com/read/28976322/medical-devices-for-paediatric-apnea-monitoring-and-therapy-past-and-new-trends
#13
Salvatore A Pullano, Ifana Mahbub, Maria Giovanna Bianco, Samira Shamsir, Syed K Islam, Mark S Gaylord, Vichien Lorch, Antonino S Fiorillo
Apnea in the paediatric population is associated with increased morbidity and mortality in a large number of developed as well as developing countries. It is even more prominent in preterm newborn infants and is commonly referred to as apnea of prematurity. Its current diagnosis and therapy involve the use of traditional technologies which often result in discomfort to the infants due to the use of invasive devices attached to their sensitive skin, especially in overnight clinical sleep analysis (for over 12- or 24-hour period)...
September 29, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28953055/predictors-of-persistent-infant-car-seat-challenge-failure
#14
Laura Mandell, Lawrence M Rhein, Henry A Feldman, Emily Bergling, Courtney Porter, Michele DeGrazia
BACKGROUND: Premature and other at-risk infants can experience cardiorespiratory problems when positioned in their car seats. The American Academy of Pediatrics recommends that all premature and at-risk infants undergo a period of observation in their car seat to monitor for apnea, bradycardia, and oxygen desaturation before hospital discharge. This Infant Car Seat Challenge (ICSC) is used to determine readiness for infant travel in a car seat. Infants failing the ICSC are discharged home in car beds and referred for a follow-up screen in the outpatient clinic...
September 25, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28947027/skeletal-dysplasia-respiratory-management-during-infancy
#15
REVIEW
Deepthi Alapati, Thomas H Shaffer
BACKGROUND: Skeletal dysplasia encompasses a variety of developmental disorders of the bone and cartilage that manifest as disproportionate shortening of limbs and trunk in the neonate. Many types of skeletal dysplasia are complicated by respiratory failure at or soon after birth and require intensive care and prolonged hospitalization. Respiratory complications in these infants are complex and are characterized by airway anomalies, restrictive lung disease due to a narrow and abnormally compliant chest wall, pulmonary hypoplasia, and central apnea...
October 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28931047/association-between-perinatal-hypoxic-ischemia-and-periventricular-leukomalacia-in-preterm-infants-a-systematic-review-and-meta-analysis
#16
REVIEW
Jichong Huang, Li Zhang, Bingyao Kang, Tingting Zhu, Yafei Li, Fengyan Zhao, Yi Qu, Dezhi Mu
BACKGROUND: Although investigators have implicated hypoxic-ischemia (HI) as a potential cause of periventricular leukomalacia (PVL), the role of clinical risk factors or markers for HI in the development of PVL remains controversial. The aim of this study was to identify perinatal HI-related factors associated with PVL. METHOD: The PubMed, EMBASE, and Cochrane Library databases were searched. The last search was performed on January 2017. Summary effect estimates (pooled odds ratios [ORs]) were calculated for each risk factor using fixed or random effects models with tests for heterogeneity and publication bias...
2017: PloS One
https://www.readbyqxmd.com/read/28891821/heart-rate-variability-as-a-feeding-intervention-outcome-measure-in-the-preterm-infant
#17
Britt F Pados, Suzanne M Thoyre, George J Knafl, William Brant Nix
BACKGROUND: Feeding interventions for preterm infants aim to reduce the physiologic stress of feeding to promote growth. Heart rate variability (HRV) is a potential noninvasive measure of physiologic stress that may be useful for evaluating efficacy of feeding interventions. PURPOSE: To evaluate whether HRV is a sensitive measure of physiologic stress compared with standard physiologic outcomes in the context of a feeding intervention study. METHODS: This was a secondary analysis of a within-subjects, cross-over design study comparing usual care feeding with a gentle, coregulated (CoReg) feeding approach in 14 infants born less than 35 weeks' postmenstrual age...
October 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28889765/effect-of-caffeine-on-superior-mesenteric-artery-blood-flow-velocities-in-preterm-neonates
#18
Mohamed A Abdel Wahed, Hanan M Issa, Soha M Khafagy, Shaimaa M Abdel Raouf
OBJECTIVE: To investigate the effect of caffeine infusion on superior mesenteric artery (SMA) blood flow velocities (BFV) in preterm infants. METHODS: Prospective observational study on 38 preterm neonates 28-33(+6) weeks gestation, who developed apnea on their first day of life, and caffeine citrate infusion was initiated at a loading dose of 20 mg/kg, followed by a maintenance dose of 5-10 mg/kg/day. Duplex ultrasound measurements of SMA BFV were recorded: peak systolic velocity (PSV), end diastolic velocity (EDV) and resistive index (RI), at 15 min before, 1-, 2- and 6-h after caffeine loading dose, and 2 h after two maintenance doses...
September 22, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28885813/asleep-at-the-wheel-obstructive-sleep-apnea
#19
Richard J Fantus
Left untreated, OSA can lead to hypertension, stroke, congestive heart failure, and atrial fibrillation and s associated with type 2 diabetes and depression.... OSA strikes people of any age, including infants, and is most commonly seen in overweight or obese men older than 40 years of age.
June 2017: Bulletin of the American College of Surgeons
https://www.readbyqxmd.com/read/28875061/impact-of-caffeine-boluses-and-caffeine-discontinuation-on-apnea-and-hypoxemia-in-preterm-infants
#20
Christa R Tabacaru, Suk Young Jang, Manisha Patel, Faranek Davalian, Santina Zanelli, Karen D Fairchild
Background: Apnea of prematurity often occurs during and following caffeine therapy. We hypothesized that number of apnea events would be impacted by adjustments in caffeine therapy. Materials and Methods: An automated algorithm was used in all infants ≤32 weeks gestation admitted to a level IV Neonatal Intensive Care Unit from 2009 to 2014 to analyze chest impedance, electrocardiogram, and oxygen saturation data around the time of serum caffeine levels, caffeine boluses while on maintenance therapy, and caffeine discontinuation...
September 1, 2017: Journal of Caffeine Research
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