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Meniere disease

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https://www.readbyqxmd.com/read/29764776/vestibulo-cochlear-function-after-cochlear-implantation-in-patients-with-meniere-s-disease
#1
Raquel Manrique-Huarte, Diego Calavia, Laura Alvarez-Gomez, Alicia Huarte, Nicolás Perez-Fernández, Manuel Manrique
OBJECTIVES: To measure the auditory (pure tone audiometry and word recognition scores) and vestibular (video head impulse test and vestibular myogenic potentials) outcomes in patients diagnosed with Meniere's disease (MD) who underwent cochlear implantation. MATERIAL AND METHODS: This prospective study included 23 cochlear implant users with MD and 29 patients diagnosed with far-advanced otosclerosis (the control group). RESULTS: The preoperative mean pure tone average thresholds were 99 and 122...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29762197/high-frequency-horizontal-semicircular-canal-function-in-certain-meni%C3%A3-re-s-disease
#2
Claudia Jerin, Rebecca Maxwell, Robert Gürkov
OBJECTIVES: To characterize video head impulse testing (vHIT) in definitive Menière's disease and to investigate the relationship between vHIT results and other audiovestibular function tests. DESIGN: Fifty-four patients with certain Menière's disease, that is, patients with clinically definite Menière's disease and endolymphatic hydrops visualized by locally enhanced inner ear MR imaging, were recruited for this study. All patients underwent vHIT. The vestibular-ocular reflex gain at 60 ms and refixation saccades were the outcome parameters measured...
May 14, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29762076/the-degeneration-of-the-vestibular-efferent-neurons-after-intratympanic-gentamicin-administration
#3
Qianru Wu, Yibo Zhang, Chunfu Dai, Yu Kong, Lijun Pan
Intratympanic gentamicin (ITG) has been used to treat refractory Ménière's disease. Disequilibrium after ITG was still a challenge for some patients, and the underlying mechanism is poorly understood. Our previous study demonstrated that gentamicin distributed in the bilateral vestibular efferent neurons (VEN) after ITG; however, does it lead to VEN damage and cause further disequilibrium in patients following ITG? In this study, we observed severe damaged gentamicin-positive neurons of VEN and severe fractured myelin layer plates around neural fibers when viewed under transmission electron microscopy at day 3 after ITG...
May 1, 2018: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
https://www.readbyqxmd.com/read/29757563/-long-term-results-of-endolymphatic-sac-mastoid-drainage-for-m%C3%A3-ni%C3%A3-re-disease
#4
Biao Chen, Ying Shi, Yue Gong, Jing Yuan Chen, Dan Mo Cui, Ting Liu, Jie Wang, Xin Ping Hao, Yong Xin Li
Objective: To investigate the long-term efficacy of endolymphatic sac mastoid drainage for Ménière disease. Method: Data from 26 patients diagnosed with MD strictly meeting the criteria issued by " Guideline of diagnosis and treatment of Meniere disease(2017)" from 2006 to 2015 were analyzed in this study.Endolymphatic sac mastoid shunt surgery was performed for each patient.The therapeutic effect was evaluated against the " Guideline of diagnosis and treatment of Meniere disease(2017)"...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29751260/forkhead-box-c1-gene-variant-causing-glaucoma-and-small-vessel-angiopathy-can-mimic-multiple-sclerosis
#5
Jagannadha R Avasarala, Julie R Jones, Curtis R Rogers
A 34-year old Caucasian female was initially diagnosed with multiple small-vessel strokes at age 20 years which were etiologically classified as secondary to anti-phospholipid antibody syndrome (APS) although she had no history or laboratory data to suggest APS. Based on her MRI of brain findings, one of her neurologists was concerned she could have multiple sclerosis (MS) and hence the patient was referred to our clinic for further evaluation. The patient's MRI of brain showed confluent lesions in the periventricular and juxta-cortical lesions that fulfil 2017 McDonald criteria for dissemination in space...
April 21, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29747962/comparison-of-vemps-vhit-and-caloric-test-outcomes-after-vestibular-neurectomy-in-meni%C3%A3-re-s-disease
#6
Andrea Canale, Federico Caranzano, Michele Lanotte, Alessandro Ducati, Francesco Calamo, Andrea Albera, Michelangelo Lacilla, Marco Boldreghini, Sergio Lucisano, Roberto Albera
OBJECTIVE: Selective unilateral vestibular neurectomy (VN) is considered a reliable surgical treatment in case of recurrent vertigo in Menière's disease (MD) because of hearing preservation and a minimally invasive posterior fossa retrosigmoid approach. The present study aimed to assess the quality of life and the long-term vestibular function in patients submitted to yearly follow-up after VN because of intractable MD. METHODS: Retrospective series of 15 MD patients undergoing retrosigmoid VN for recurrent vertigo...
May 7, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29747309/-etiological-analysis-on-patients-with-vertigo-or-dizziness
#7
H Xue, Y Chong, Z D Jiang, Z L Liu, L Ding, S L Yang, L Wang, W P Xiang
Objective: To explore the spectrum of causes for patients with vertigo or dizziness in the Department of Neurology, and provide a reference for diagnosis and treatment of patients with vertigo or dizziness. Methods: Clinical data of patients in the Department of Neurology, Baotou Central Hospital between January 2016 and September 2017 was retrospectively analyzed. The target group under study was diagnosed based on the uniform diagnostic criteria. Results: A total of 9 200 patients with a chief complaint of vertigo or dizziness were included...
April 24, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29747307/-clinical-features-and-imaging-characteristics-of-meniere-s-disease-verified-by-intravenous-gadolinium-contrast-enhanced-magnetic-resonance-imaging
#8
S M Shi, W F Sun, W Q Wang
Objective: To analyze the clinical features and imaging characteristics of Meniere's disease (MD)verified by intravenous gadolinium contrast-enhanced magnetic resonance imaging(MRI). Methods: A total of 174 patients with Meniere's disease were involved in this study between March 2016 and October 2017. All of them underwent 3D-fluid attenuated inversion recovery (FLAIR) MRI and presented endolymphatic hydrops and clinical characteristics of suspected Meniere's disease. The clinical characteristics, the grades of endolymphatic hydrops (EH) using Nakashima grading standard were analyzed, and the correlation between grade and clinical features was evaluated...
April 24, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29738389/endolymphatic-sac-decompression-with-intra-sac-dexamethasone-injection-in-meni%C3%A3-re-s-disease
#9
Dennis I Bojrab, Michael J LaRouere, Dennis I Bojrab, Seilesh C Babu, Eric W Sargent, Eleanor Y Chan, Robert S Hong
OBJECTIVE: Endolymphatic sac decompression surgery (ELSD) may be used to treat patients who have Menière's 's disease refractory to medical therapy. In this study, we investigated whether or not the injection of steroid into the endolymphatic sac at the time of ELSD provides additional benefit to patient outcomes. STUDY DESIGN: Randomized prospective single-blinded placebo-controlled study. SETTING: Tertiary center. PATIENTS: Patients with Menière's disease with poorly controlled vertigo despite medical therapy and serviceable hearing that were offered ELSD...
June 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29737749/-recurrent-low-frequency-sensorineural-deafness
#10
REVIEW
Ying Lin, Jin Ling Wang, Fei Sun, Jin Jin Shen, Zhao Xia Wang, Jian Hua Qiu, Ding Jun Zha
Low frequency sensorineural deafness is a common subtype of idiopathic sudden deafness. Certain patients suffered recurrent attacks without vertigo, much alike Meniere's disease. Few of them developed into definite Meniere's disease during long-term follow-up in many clinical studies. Although the pathophysiology of recurrent low frequency deafness is yet unknown, the desease is considered associated with early state of endolymphatic hydrops or migraine. Otologists shall be aware of its clinical course and careful explanation is necessary at time of initial informed consent...
March 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29733259/alcohol-consumption-in-meni%C3%A3-re-s-disease-patients
#11
Inés Sánchez-Sellero, Elena San-Román-Rodríguez, Sofía Santos-Pérez, Marcos Rossi-Izquierdo, Andrés Soto-Varela
OBJECTIVES: Dietary changes are useful in the management of Menière's disease; regarding alcohol, many clinicians recommend to avoid or reduce its consumption. However, there are no researches aimed to evaluate whether habitual alcohol consumption is more prevalent and/or more intense in patients with Menière's disease. METHODS: Cross-sectional, observational, case-control study, including three groups: patients with Menière's disease, patients with vertigo of other origins, and control subjects...
May 7, 2018: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29698363/relationship-between-audio-vestibular-functional-tests-and-inner-ear-mri-in-meniere-s-disease
#12
Raphaële Quatre, Arnaud Attyé, Alexandre Karkas, Agnès Job, Georges Dumas, Sébastien Schmerber
OBJECTIVES: Meniere's disease is an inner ear disorder generally attributed to an endolymphatic hydrops. Different electrophysiological tests and imaging techniques have been developed to improve endolymphatic hydrops diagnosis. The goal of our study was to compare the sensitivity and the specificity of delayed inner ear magnetic resonance imaging (MRI) after intravenous injection of gadolinium with extratympanic clicks electrocochleography (EcochG), phase shift of distortion product otoacoustic emissions (shift-DPOAEs), and cervical vestibular-evoked myogenic potentials (cVEMP) for the diagnosis of Meniere's disease...
April 25, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29692756/hierarchical-cluster-analysis-of-semicircular-canal-and-otolith-deficits-in-bilateral-vestibulopathy
#13
Alexander A Tarnutzer, Christopher J Bockisch, Elena Buffone, Konrad P Weber
Background: Gait imbalance and oscillopsia are frequent complaints of bilateral vestibular loss (BLV). Video-head-impulse testing (vHIT) of all six semicircular canals (SCCs) has demonstrated varying involvement of the different canals. Sparing of anterior-canal function has been linked to aminoglycoside-related vestibulopathy and Menière's disease. We hypothesized that utricular and saccular impairment [assessed by vestibular-evoked myogenic potentials (VEMPs)] may be disease-specific also, possibly facilitating the differential diagnosis...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29688822/clinical-subtyping-of-m%C3%A3-ni%C3%A3-re-s-disease
#14
John S Phillips, Louisa Murdin, Peter Rea, Liam Sutton
Fundamentally, Ménière's disease is a constellation of symptoms and, as such, may represent the final common pathway for a number of disease processes, as opposed to being the consequence of a single isolated pathology. Within this type of consideration, much can be learned regarding the etiology, presentation, prognosis, and treatment of these individual conditions by applying subtyping techniques currently employed to better understand similar disease processes that are encountered in other allied fields of medicine...
April 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29663119/multicenter-data-banking-in-management-of-dizzy-patients-first-results-from-the-dizzynet-registry-project
#15
Eva Grill, Gülden Akdal, Sandra Becker-Bense, Steffen Hübinger, Doreen Huppert, Erna Kentala, Ralf Strobl, Andreas Zwergal, Nese Celebisoy
PURPOSE: Comprehensive phenotypical data across countries is needed to understand the determinants, prognosis and consequences of vestibular disease. The registry is a data repository for the members of the European DizzyNet. We report results from a pilot study using data from Turkey and Germany. METHODS: The pilot study included a convenience sample of patients aged 18 or above referred to Ege University Medical School Hospital, Dokuz Eylül University Hospital, Izmir, Turkey, and the German Center for German Center for Vertigo and Balance Disorders, University on Munich, Germany, with symptoms of vertigo or dizziness...
April 16, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29649052/recurrence-in-benign-paroxysmal-positional-vertigo-a-large-single-institution-study
#16
Alexander L Luryi, Juliana Lawrence, Dennis I Bojrab, Michael LaRouere, Seilesh Babu, John Zappia, Eric W Sargent, Eleanor Chan, Ilka Naumann, Robert S Hong, Christopher A Schutt
OBJECTIVE: To report rates of recurrence in benign paroxysmal positional vertigo (BPPV) and associated patient and disease factors. STUDY DESIGN: Retrospective chart review. SETTING: Single high-volume otology practice. PATIENTS: Patients diagnosed with BPPV from 2007 to 2016 with documented resolution of symptoms. INTERVENTION: Diagnostic and particle repositioning maneuvers for BPPV. MAIN OUTCOME MEASURES: BPPV recurrence, time to recurrence, and ear(s) affected at recurrence...
April 11, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29624570/are-diuretics-effective-for-m%C3%A3-ni%C3%A3-re-s-disease
#17
Andrés Rosenbaum, Matías Winter
INTRODUCTION: Ménière`s disease is an inner ear disorder characterized by episodes of spontaneous vertigo, fluctuating hearing loss and tinnitus. Diuretics have been widely used for the treatment of attacks, but there is controversy about their effectiveness. METHODS: To answer this question we used Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others...
March 28, 2018: Medwave
https://www.readbyqxmd.com/read/29619111/intratympanic-gentamicin-for-intractable-m%C3%A3-ni%C3%A3-re-s-disease-a-review-and-analysis-of-audiovestibular-impact
#18
Sertaç Yetişer
Introduction  Intratympanic gentamicin regulates the symptoms in most patients with incapacitating Ménière's disease. The treatment protocols have changed over the years from medical labyrinthectomy to preservation of vestibular function. Objectives  This study aims to review the audiovestibular response related to the effect of the drug in controlling vertigo. Data Synthesis  Articles were identified by means of a search in the PubMed database using the key words Meniere and intratympanic or transtympanic gentamicin ...
April 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29582143/genetic-contribution-to-vestibular-diseases
#19
REVIEW
Alvaro Gallego-Martinez, Juan Manuel Espinosa-Sanchez, Jose Antonio Lopez-Escamez
Growing evidence supports the contribution of allelic variation to vestibular disorders. Heritability attributed to rare allelic variants is found in familial vestibular syndromes such as enlarged vestibular aqueduct syndrome or familial Meniere disease. However, the involvement of common allelic variants as key regulators of physiological processes in common and rare vestibular diseases is starting to be deciphered, including motion sickness or sporadic Meniere disease. The genetic contribution to most of the vestibular disorders is still largely unknown...
March 26, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29577849/facial-nerve-stimulation-after-cochlear-implantation-our-experience-in-448-adult-patients
#20
Joana Sanches Pires, Ana Sofia Melo, Ricardo Caiado, Jorge Humberto Martins, João Elói Moura, Luís Filipe Silva
Facial nerve stimulation (FNS) after cochlear implant activation is a well-known side effect, with an incidence rate raging between 1% and 14.9%. Some causes of deafness have been associated with a higher incidence of this entity, however, there is still no consensus regarding its pathophysiological mechanisms. Although FNS can be solved with changes in speech processor programming, in some cases this can lead to a decrease in performance. The aim of this work was to review the epidemiologic, clinical aspects, and performance results in a group of FNS after cochlear implantation...
March 25, 2018: Cochlear Implants International
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