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Renal cancer, bladder cancer, urolithiasis

Diego Martin-Sanchez, Miguel Fontecha-Barriuso, Maria Dolores Sanchez-Niño, Adrian M Ramos, Ramiro Cabello, Carmen Gonzalez-Enguita, Andreas Linkermann, Ana Belén Sanz, Alberto Ortiz
Urinary tract-associated diseases comprise a complex set of disorders with a variety of etiologic agents and therapeutic approaches and a huge global burden of disease, estimated at around 1 million deaths per year. These diseases include cancer (mainly prostate, renal, and bladder), urinary tract infections, and urolithiasis. Cell death plays a key role in the pathogenesis and therapy of these conditions. During urinary tract infections, invading bacteria may either promote or prevent host cell death by interfering with cell death pathways...
January 25, 2018: Cell Death & Disease
D P Kholtobin, E V Kulchavenya
Urogenital tuberculosis does not have pathognomonic symptoms, so diagnostic errors are quite common. This systematic review of literature was conducted to identify the causes and estimate the incidence of erroneous diagnoses. We critically evaluated some articles in which the authors describe observations of urogenital tuberculosis as rare and unusual because they never encountered this disease, but in fact that were typical manifestations of genitourinary tuberculosis. The authors analyzed and illustrated the features of urinary tuberculosis in patients with pulmonary tuberculosis, differential diagnosis of urogenital tuberculosis and kidney cancer and male genitourinary organs, described errors in the diagnosis of urethral, testicular, penile, prostatic and epididymal tuberculosis...
October 2017: Urologii︠a︡
Stavros Sfoungaristos, Ioannis Mykoniatis, Evangelos Poulios, Dimitrios Paikos, Dimitrios Hatzichristou
Mainz pouch II is a reliable and viable technique of continent urinary diversion. Patients are at increased risk of long-term complications including urolithiasis of the upper urinary tract and reservoir. We report the case of a 67-year-old male with prior Mainz pouch II due to invasive bladder cancer treated for a large renal calculus. Percutaneous nephrolithotomy (PCNL) was successfully performed. Stone management in these type of patients is of increased interest due to existed "anatomical challenges" concerning the access and safety during the procedure...
2016: Prague Medical Report
Chien-Liang Lin, Wen-Tsung Huang, Wen-Chou Fan, Yin-Hsun Feng, Chia-Ho Lin, Chian-Shiung Lin, Chih-Cheng Lu, Tse-Chou Cheng, Chao-Jung Tsao, Sheng-Hsiang Lin
The aim of this study was to investigate cancer risk in patients with a history of urolithiasis and to determine whether intervention for calculi attenuated the risk of subsequent urinary tract cancer (UTC).Using data from the National Health Insurance Research Database in Taiwan, we performed a nationwide cohort study enrolling participants (n = 42,732) aged > 30 years who were diagnosed with urinary tract calculi between 2000 and 2009. Age- and gender-matched insured individuals (n = 213,660) found in the health service records over the same period were recruited as the control group...
December 2016: Medicine (Baltimore)
F P Prete, A Pezzolla, V De Leo, G Di Palma, F Prete
BACKGROUND: Inguino-scrotal herniation of the ureter is a rare and difficult situation for a surgeon, especially if only recognized during inguinal hernia repair. METHODS: An 83-year-old gentleman, with a previous history of radiation treatment for squamous anal cancer, presented with a large left inguinoscrotal hernia causing occasional pain at the base of the scrotum. Follow-up, post-radiation therapy CT scan showed a hernia sac containing the bladder and large bowel...
December 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
F Roghmann, M Gockel, J Schmidt, J Hanske, N von Landenberg, B Löppenberg, K Braun, C von Bodman, J Pastor, J Palisaar, J Noldus, M Brock
BACKGROUND: We analyzed complications associated with urinary diversion after radical cystectomy (RC) and ileal conduit (IC) for bladder cancer (BCa). PATIENTS AND METHODS: A total of 305 BCa patients after RC with IC were included in the study (June 2003-December 2010). IC complications (peristomal hernia, IC stenosis, stenosis of the ureteral anastomosis, IC bleeding, urolithiasis, urinary infections, and renal insufficiency) were identified according to the Clavien-Dindo classification (CDC)...
April 2015: Der Urologe. Ausg. A
Christian Gratzke, Alexander Bachmann, Aurelien Descazeaud, Marcus J Drake, Stephan Madersbacher, Charalampos Mamoulakis, Matthias Oelke, Kari A O Tikkinen, Stavros Gravas
CONTEXT: Lower urinary tract symptoms (LUTS) represent one of the most common clinical complaints in adult men and have multifactorial aetiology. OBJECTIVE: To develop European Association of Urology (EAU) guidelines on the assessment of men with non-neurogenic LUTS. EVIDENCE ACQUISITION: A structured literature search on the assessment of non-neurogenic male LUTS was conducted. Articles with the highest available level of evidence were selected...
June 2015: European Urology
Luca Carmignani, Giorgio Bozzini, Vincenzo Nicosia, Massimo Consentino, Stefano Picozzi, Stefano Casellato, Luca Lunelli
OBJECTIVES: Starting from the UK experience, we decided to test both the feasibility and the advantages of this diagnostic pathway now established in an Italian hospital. We analyzed the outcomes in detecting transitional cell carcinoma (TCC) of the bladder, other malignant and non-malignant conditions. MATERIALS AND METHODS: Between April and December 2010, one hundred and fifty patients presenting with hematuria were referred to the Hematuria One Stop Clinic (HOSC) at our Institution...
October 2011: Urologia
El-Sayed Ashraf Khalil
PURPOSE: To study the long term complications of ileal conduit urinary diversion in 36 patients with invasive urinary bladder cancer who lived more than 5 years after surgery. PATIENTS AND METHODS: A retrospective study included 36 long term survivors (survival 5 years or greater) with invasive bladder cancer who did radical cystectomy or anterior pelvic excentration with ileal conduit urinary diversion at the National Cancer Institute, Cairo University before January 2004...
March 2010: Journal of the Egyptian National Cancer Institute
M Brod'ák, M Romzová, J Kosina
INTRODUCTION: The diabetes mellitus is risk factor for urologic surgery. The best prevention of complications is excellent compensation of diabetes, appropriated management of anesthesia and good post surgery care. The diabetes is etiologic risk factor many urologic diseases including malignant. UROLOGIC SURGERY: The diabetes is intensively evaluated in uro-oncology and it seems that renal cell carcinoma and bladder cancer incidence is higher in diabetic patients. The link between prostate cancer and diabetes is not clear, yet...
May 2008: Vnitr̆ní Lékar̆ství
H Kanayama, M Takahashi, M Nishitani, S Kagawa
PURPOSE: In order to define the clinical significance of serum soluble Interferon alpha/beta receptor (sIFN alpha/beta R) levels, we determined sIFN alpha/beta R concentrations in serum of patients with urological benign and malignant diseases. MATERIALS AND METHODS: Serum sIFN alpha/beta R levels were measured in normal control (n = 22), patients with benign diseases (n = 50) included urolithiasis (n = 16), prostatic hypertrophy (n = 13), and malignant diseases included bladder cancer (n = 49), renal cell carcinoma (n = 30) and prostate cancer (n = 36) by the enzyme linked immunosolbent assay (ELISA) using monoclonal and polyclonal antibodies...
September 2000: Nihon Hinyōkika Gakkai Zasshi. the Japanese Journal of Urology
S Mourah, O Cussenot, V Vimont, F Desgrandchamps, P Teillac, B Cochant-Priollet, A Le Duc, J Fiet, H Soliman
Loss of heterozygosity (LOH) and alterations in microsatellite DNA markers have been reported in bladder-cancer tumors. We have studied, in a blinded fashion, using PCR-based microsatellite analysis, genetic alterations of cells exfoliated in urine of 59 Caucasian patients and control patients; 31 with initially confirmed bladder transitional-cell carcinoma (TCC), 17 with signs and symptoms suggestive of bladder cancer, 6 control patients who underwent renal transplantation, and 5 control patients with urolithiasis...
December 18, 1998: International Journal of Cancer. Journal International du Cancer
K Noto, M Fujime, H Isobe, Y Wakumato, Y Kawachi
BACKGROUND: Although Carbohydrate antigen19-9 (CA19-9) is known to be high of its positive rate in blood in pancreatic cancer, etc., recently there have been scattered of cases of urothelial carcinoma in which elevated CA19-9 levels have been detected in both serum and urine. In this study we determined both urine and serum levels of CA19-9 in order to evaluate their diagnostic role of urinary CA19-9. MATERIALS: A total 82 patients, i.e., 32 with bladder cancer, 4 with renal pelvic/ureteral cancer, 5 with renal cancer, 13 with prostatic cancer, 5 with other malignancies, 10 with prostatic hyperplasia, 6 with urolithiasis, 7 with other benign diseases, served as the subjects of this study...
March 1997: Nihon Hinyōkika Gakkai Zasshi. the Japanese Journal of Urology
Y Senga, G Kimura, T Hattori, K Yoshida
OBJECTIVES: CYFRA 21-1 is a new tumor marker that measures cytokeratin 19 (CK-19) fragments by a sandwich enzyme-linked immunosorbent assay (ELISA). In this study, we evaluated the usefulness of serum and urine CYFRA 21-1 as a tumor marker for bladder cancers. METHODS: We measured serum and urine CYFRA 21-1 levels in a group of patients with bladder cancer (n = 58) and a group without bladder cancer (n = 220). The latter group was divided into five subgroups of patients (those with cystitis, benign prostatic hyperplasia (BPH), urolithiasis, or renal dysfunction, and a group of healthy, controls)...
November 1996: Urology
Y Mizutani, Y Okada, T Terachi, Y Kakehi, O Yoshida
OBJECTIVES: To measure the serum levels of granulocyte colony-stimulating factor (G-CSF) in patients with urinary bladder tumour (UBT) or various urological malignant tumours, and to assess G-CSF production by tumour cells. PATIENTS AND METHODS: Peripheral blood was obtained, before operation or anti-cancer therapy, from 141 patients with UBT, 37 patients with other urological malignant tumours (21 with renal cell carcinoma, nine with renal pelvic or ureteric tumours, five with prostatic cancer, and two with testicular cancer), 38 patients with benign urological diseases (21 with benign prostatic hypertrophy, 11 with urolithiasis and six with a varicocele), and from 15 healthy donors...
November 1995: British Journal of Urology
A N Shpigel'
The author characterizes in detail 4340 patients with diffuse renal lesions (chronic glomerulonephritis, renal amyloidosis, lupoid nephritis, diabetic glomerulosclerosis and nephrosclerosis) coupled with different diseases of the urinary organs including urolithiasis, cancerous and tuberculous processes, purulent diseases of the kidneys and prostatic lesions. Stage III chronic renal failure (CRF) was revealed in 2073 (57.1%) out of the 4340 patients. All of them died because of uremia. The mean lifespan of the patients was 1...
1990: Terapevticheskiĭ Arkhiv
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