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journal of american college of cardiology

Andrew Elagizi, Tobias S Köhler, Carl J Lavie
There is an ongoing debate in the medical community regarding the effects of testosterone on cardiovascular (CV) health. For decades, there has been conflicting evidence regarding the association of endogenous testosterone levels and CV disease (CVD) events that has resulted in much debate and confusion among health care providers and patients alike. Testosterone therapy has become increasingly widespread, and after the emergence of studies that reported increased CVD events in patients receiving testosterone therapy, the US Food and Drug Administration (FDA) released a warning statement about testosterone and its potential risk regarding CV health...
December 20, 2017: Mayo Clinic Proceedings
John Cordina, Gillian E Mead
BACKGROUND: Atrial fibrillation is the commonest cardiac dysrhythmia. It is associated with significant morbidity and mortality. There are two approaches to the management of atrial fibrillation: controlling the ventricular rate or converting to sinus rhythm in the expectation that this would abolish its adverse effects. OBJECTIVES: To assess the effects of pharmacological cardioversion of atrial fibrillation in adults on the annual risk of stroke, peripheral embolism, and mortality...
November 15, 2017: Cochrane Database of Systematic Reviews
Gillian E Mead, Andrew Elder, Andrew D Flapan, John Cordina
BACKGROUND: Atrial fibrillation increases stroke risk and adversely affects cardiovascular haemodynamics. Electrical cardioversion may, by restoring sinus rhythm, improve cardiovascular haemodynamics, reduce the risk of stroke, and obviate the need for long-term anticoagulation. OBJECTIVES: To assess the effects of electrical cardioversion of atrial fibrillation or flutter on the risk of thromboembolic events, strokes and mortality (primary outcomes), the rate of cognitive decline, quality of life, the use of anticoagulants and the risk of re-hospitalisation (secondary outcomes) in adults (>18 years)...
November 15, 2017: Cochrane Database of Systematic Reviews
Martin Mayer
AIM: A crucial element of evidence-based healthcare is the sound understanding and use of statistics. As part of instilling sound statistical knowledge and practice, it seems useful to highlight instances of unsound statistical reasoning or practice, not merely in captious or vitriolic spirit, but rather, to use such error as a springboard for edification by giving tangibility to the concepts at hand and highlighting the importance of avoiding such error. This article aims to provide an instructive overview of two key statistical concepts: effect modification and P values...
December 2017: International Journal of Evidence-based Healthcare
Muhammad Shahzeb Khan, Waqas Ullah, Irbaz Bin Riaz, Nizar Bhulani, Warren J Manning, Srini Tridandapani, Faisal Khosa
BACKGROUND: With limited health care resources, bibliometric studies can help guide researchers and research funding agencies towards areas where reallocation or increase in research activity is warranted. Bibliometric analyses have been published in many specialties and sub-specialties but our literature search did not reveal a bibliometric analysis on Cardiovascular Magnetic Resonance (CMR). The main objective of the study was to identify the trends of the top 100 cited articles on CMR research...
November 21, 2016: Journal of Cardiovascular Magnetic Resonance
Clifford J Kavinsky, Fred M Kusumoto, Anthony A Bavry, Steven R Bailey, Kenneth A Ellenbogen, Paul L Hess, Daniel L Lustgarten, Issam D Moussa, Christian Spies
No abstract text is available yet for this article.
May 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
David R Holmes, Michael J Mack
No abstract text is available yet for this article.
November 19, 2015: New England Journal of Medicine
(no author information available yet)
In the article by Smith et al, “AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2011 Update: A Guideline From the American Heart Association and American College of Cardiology Foundation,” which published online November 3, 2011, and appeared with the November 29, 2011, issue of the journal (Circulation. 2011;124:2458–2473. DOI: 10.1161/CIR.0b013e318235eb4d.), several corrections were needed. The authors regret the errors...
April 14, 2015: Circulation
Jörg Neuzner
In 2005, Bob Hauser published a paper in the Journal of the American College of Cardiology entitled "The growing mismatch between patient longevity and the service life of Implantable Cardioverter-Defibrillators". Now, nearly a decade later, I would like to perform a second look on the problem of a mismatching between ICD device service life and the survival of ICD recipients. Since 2005, the demographics of the ICD population has changed significantly. Primary prevention has become the dominant indication in defibrillator therapy and device implantation is indicated more and more in earlier stages of cardiac diseases...
June 2015: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
Scott M Grundy
Recent guidelines for cholesterol management proposed by the American College of Cardiology (ACC) and American Heart Association (AHA) recommended statin therapy for most men in their 60s and most women in their 70s. If these guidelines are followed in the United States, most adults will eventually take statins. A companion article in this journal goes a step further by proposing statin initiation for mostly everyone about 10 years earlier. Treatment in ACC/AHA guidelines does not depend on cholesterol levels, for either statin initiation or treatment goals...
November 1, 2014: American Journal of Cardiology
Jacques Blacher, Hélène Lelong, Sandrine Kretz, Alexandra Yannoutsos, Takeshi Kondo, Michel Safar
During year 2013, several recommendations for the management of hypertension were published: recommendations of the French and European Societies of Hypertension and two recommendations from the USA, those from the ACC/AHA/CDC groups and those from the JNC 8. The recommendations of the JNC 8 are not, strictly speaking, the recommendations of JNC 8, since they are neither endorsed by their sponsor: the National Heart, Lung and Blood Institute (NHLBI), nor by any other supervisor. They only commit their authors...
October 2014: La Presse Médicale
Dong Zhao, Benqing Zhang
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether valve replacement was associated with higher morbidity and mortality rates than valve repair in patients with native active valve endocarditis. Altogether 662 papers were found using the reported search, of which 7 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated...
December 2014: Interactive Cardiovascular and Thoracic Surgery
Michael J Pencina, Ann Marie Navar-Boggan, Ralph B D'Agostino, Ken Williams, Benjamin Neely, Allan D Sniderman, Eric D Peterson
BACKGROUND: The 2013 guidelines of the American College of Cardiology and the American Heart Association (ACC-AHA) for the treatment of cholesterol expand the indications for statin therapy for the prevention of cardiovascular disease. METHODS: Using data from the National Health and Nutrition Examination Surveys of 2005 to 2010, we estimated the number, and summarized the risk-factor profile, of persons for whom statin therapy would be recommended (i.e., eligible persons) under the new ACC-AHA guidelines, as compared with the guidelines of the Third Adult Treatment Panel (ATP III) of the National Cholesterol Education Program, and extrapolated the results to a population of 115...
April 10, 2014: New England Journal of Medicine
Stephan Willems, Boris A Hoffmann, Benjamin Schaeffer, Arian Sultan, Doreen Schreiber, Jakob Lüker, Daniel Steven
The involvement of the Purkinje system in a subset of patients with idiopathic ventricular fibrillation or polymorphic VT/VF related to structural heart disease was first demonstrated in the pioneering work of Michel Haissaguerre and co-workers (Circulation 106:962-967, 2002 and Lancet 359:677-678, 2002). It is very important to identify these patients with recurrent episodes of ventricular fibrillation and/or ICD shocks with regard to the presence of triggering premature ventricular contractions (PVC), which may be amenable to mapping and catheter ablation by screening Holter and ICD recordings...
September 2014: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Keith A A Fox, Caroline Telfer
Professor Keith AA Fox speaks to Caroline Telfer, Commissioning Editor. Professor Keith AA Fox is the British Heart Foundation and the Duke of Edinburgh Professor of Cardiology at the University of Edinburgh (UK). He is a founding fellow of the European Society of Cardiology and is currently Chair of the Programme of the European Society of Cardiology. In addition, he was President of the British Cardiovascular Society from 2009 to 2012. Professor Fox gave the State-of-the-Art lecture on acute coronary syndromes at the American Heart Association, as well as the 2009 Plenary lecture at the European Society of Cardiology-American College of Cardiology Symposium, the Lord Rayner lecture of the Royal College of Physicians (London, UK) and the Sir Stanley Davidson Lecture of the Royal College (Edinburgh, UK)...
January 2014: Future Cardiology
Mark R Thomas, Robert F Storey
The discovery of the antiplatelet effect of low-dose aspirin led to the hugely successful strategy of dual antiplatelet therapy in patients with acute coronary syndromes (ACS). Increasing the dose of aspirin beyond 75-100 mg has never been shown to offer additional efficacy in ACS patients but could possibly increase the risk of bleeding. In the Platelet Inhibition and Patients Outcome (PLATO) study, higher doses of aspirin appeared to neutralise the additional benefit of the potent P2Y12 inhibitor ticagrelor compared to clopidogrel (Circulation 124: 544-554, 2011)...
February 2014: Journal of Cardiovascular Translational Research
Sobia Mujtaba, Jessica M Peña, Mohan Pamerla, Cynthia C Taub
The last twenty years have seen an explosive growth in cardiovascular disease research. The purpose of our study was to evaluate the characteristics of published research in the field of non-invasive cardiovascular imaging research from 1991-2011. Our aims were to determine: (1) the origin of the studies (international or from the U.S.) (2) differences in funding sources for U.S. publications and (3) if there has been an evolving trend pertaining to the mode of imaging. We evaluated characteristics of original research articles from Circulation, Circulation cardiovascular imaging, Journal of the American College of Cardiology (JACC), Journal of the American College of Cardiology cardiovascular imaging, Journal of the American Medical Association and the New England Journal of Medicine for the years 1991-91, 2001-02 and 2010-11...
2013: American Journal of Cardiovascular Disease
Stéphanie Perrier, Michel Kindo, Sébastien Gerelli, Jean-Philippe Mazzucotelli
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was as follows: is coronary artery bypass graft (CABG) surgery superior to percutaneous coronary intervention (PCI) in terms of in-hospital mortality and morbidity and long-term outcomes in patients with acute myocardial infarction (MI)? A total of 104 papers were returned using the selected search. Of these, six represented the best evidence to answer the clinical question. The selection criteria were comparative studies with only PCI and CABG groups in patients with acute MI...
December 2013: Interactive Cardiovascular and Thoracic Surgery
Tuan V Mai, Donna L Agan, Paul Clopton, Glenn Collins, Anthony N DeMaria
OBJECTIVES: The aim of this study was to determine the extent, type (e.g., staff, equipment), and sources of funding for published cardiovascular research. BACKGROUND: Important cardiovascular research is often performed without direct financial support. The degree to which medical research is conducted on an unfunded basis remains uncertain. METHODS: We sent an electronic survey (Survey Monkey) to 938 corresponding authors who published papers in the Journal of the American College of Cardiology from 2007 through 2009...
January 22, 2013: Journal of the American College of Cardiology
Emil L Fosbøl, Philip L Fosbøl, Robert A Harrington, Zubin J Eapen, Eric D Peterson
BACKGROUND: The transition of scientific knowledge from discovery into practice is less than ideal. A key step in this translation occurs when presentations from major meetings are published in peer-reviewed literature, yet the completeness and speed of this process are not known. We performed a systematic and automated evaluation of rates, timing, and correlates of publication from scientific abstracts presented at 3 major cardiovascular conferences. METHODS AND RESULTS: Using an automated computer algorithm, we searched the ISI Web of Science to identify peer-reviewed publications of abstracts presented at the American Heart Association (AHA), American College of Cardiology (ACC), and European Society of Cardiology (ESC) scientific sessions from 2006 to 2008...
December 11, 2012: Circulation
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