Pedro Gutiérrez-Castrellón, Anna Alejandra Ortíz-Hernández, Beatriz Llamosas-Gallardo, Mario A Acosta-Bastidas, Carlos Jiménez-Gutiérrez, Luisa Diaz-García, Anahí Anzo-Osorio, Juliana Estevez-Jiménez, Irma Jiménez-Escobar, Rosa Patricia Vidal-Vázquez
RATIONALE: Despite major advances in treatment, acute diarrhea continues to be a public health problem in children under five years. There is no systematic approach to treatment and most evidence is assembled comparing active treatment vs. placebo. OBJECTIVE: Systematic review of evidence on efficacy of adjuvants for treatment of acute diarrhea through a network meta-analysis. METHODS: A systematic search of multiple databases searching clinical trials related to the use of racecadotril, smectite, Lactobacillus GG, Lactobacillus reuteri, Saccharomyces boulardii and zinc as adjuvants in acute diarrhea was done...
2015: Gaceta Médica de México