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Lichen ruber

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https://www.readbyqxmd.com/read/27529527/-coincidence-of-a-chronic-hepatitis-c-and-an-autoimmune-hepatitis-type-3-successful-therapy-with-the-new-direct-acting-antiviral-agents
#1
N Dikopoulos, E Zizer
Chronic hepatitis C infection may be associated with several features of autoimmunity (i. e., detection of different kinds of autoantibodies in the serum). Hepatitis C is also associated with different autoimmune diseases, such as autoimmune thyroiditis, lichen ruber planus, and membranous glomerulonephritis being the most relevant. There are very few cases of a coincidence of chronic hepatitis C with an autoimmune hepatitis, that is usually diagnosed by detection of specific autoantibodies and typical histological features...
August 2016: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/26875085/monitoring-carcinogenesis-in-a-case-of-oral-squamous-cell-carcinoma-using-a-panel-of-new-metabolic-blood-biomarkers-as-liquid-biopsies
#2
Martin Grimm, Sebastian Hoefert, Michael Krimmel, Thorsten Biegner, Oliver Feyen, Peter Teriete, Siegmar Reinert
INTRODUCTION: One of the common malignant tumors of the head and neck worldwide with generally unfavorable prognosis is squamous cell carcinoma (OSCC) of the oral cavity. Early detection of primary, secondary, or recurrent OSCC by liquid biopsy tools is much needed. CASE PRESENTATION: Twelve blood biomarkers were used for monitoring a case of OSCC suffering from precancerous oral lichen ruber planus mucosae (OLP). After curative R0 tumor resection of primary OSCC (buccal mucosa), elevated epitope detection in monocytes (EDIM)-Apo10, EDIM-transketolase-like-1 (TKTL1), squamous cell carcinoma antigen (SCC-Ag), total serum lactate dehydrogenase (LDH), and its anaerobic isoforms (LDH-4, LDH-5) decreased to normal levels...
September 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/26711698/glucocorticoid-receptors-gr%C3%AE-and-gr%C3%AE-are-expressed-in-inflammatory-dermatoses
#3
Minna E Kubin, Päivi M Hägg, Nina Kokkonen, Juha P Väyrynen, Kirsi-Maria Haapasaari, Jyri Moilanen, Matti Kallioinen, Tiina Hurskainen, Kaisa Tasanen
BACKGROUND: Glucocorticoids (GC) are the most commonly used anti-inflammatory drugs in dermatology. The actions of GCs are mediated by the glucocorticoid receptor (GR). Alternative splicing of GR mRNA gives rise to different isoforms, GRα and GRβ being the most important. GRβ antagonizes the activity of GRα and its up-regulation has been associated with glucocorticoid insensitivity in several non-cutaneous inflammatory diseases. METHODS: Using immunohistochemical stainings, we analyzed the expression of GRα and GRβ in lesional skin samples of patients with atopic dermatitis, lichen ruber planus, eczema nummulare and lichen simplex chronicus...
January 2016: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/26547800/altered-expression-of-keratin-14-in-lesional-epidermis-of-autoimmune-skin-diseases
#4
Xiaoying Wei, Katharina Fricker, Alexander H Enk, Eva N Hadaschik
BACKGROUND: Keratin 14 (K14) is an intermediate filament protein that is mainly expressed in the basal layer of healthy stratified epithelia. K14 has been identified as an autoantigen in the autoimmune-mediated skin disease of Scurfy mice and patients with the "immune dysregulation polyendocrinopathy, enteropathy, and X-linked" syndrome. OBJECTIVES: To examine whether K14 is a target protein in autoimmune skin diseases (ASD), we analyzed the expression pattern of K14 in lesional skin of patients with lichen ruber, cutaneous lupus erythematosus, dermatomyositis, graft-versus-host disease, psoriasis, and pemphigus vulgaris, and evaluated the reactivity of patient sera with recombinantly expressed and epidermis-derived K14...
June 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/26333514/among-the-s100-proteins-s100a12-is-the-most-significant-marker-for-psoriasis-disease-activity
#5
D Wilsmann-Theis, J Wagenpfeil, D Holzinger, J Roth, S Koch, S Schnautz, T Bieber, J Wenzel
BACKGROUND: Psoriasis is a chronic skin disease with deregulation of proteins in the immune system. These proteins include members of the heterogeneous S100 family, which have been discussed as potential biomarkers for disease severity. OBJECTIVE: The aim of this study was to evaluate the impact of S100A7, S100A8, S100A9 and S100A12 as possible markers for disease activity in patients with psoriasis skin disease. PATIENTS AND METHODS: S100A7, S100A8, S100A9 and S100A12 mRNA expression was determined in the skin of patients with psoriasis and controls (N = 341) by gene expression analyses...
July 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/26110723/t-zellplastizit%C3%A3-t-bei-entz%C3%A3-ndlichen-hauterkrankungen-die-guten-die-schlechten-und-die-cham%C3%A3-leons
#6
Martina Gatzka, Karin Scharffetter-Kochanek
Nach dem Konzept der T-Zellplastizität können periphere T-Zellen - sobald sie sich in eine spezifische T-Zell-Untergruppe differenziert haben - in Reaktion auf neue Umweltfaktoren oder veränderte Signale den Phänotyp einer anderen Helferzell-Untergruppe in Bezug auf Zytokinproduktion und regulatorische Funktionen annehmen. Die T-Zellplastizität - besonders die Umwandlung regulatorischer T-Zellen (Tregs) zu IL-17-produzierenden Entzündungszellen - wurde in jüngster Zeit bei verschiedenen T-Zell-vermittelten entzündlichen Erkrankungen wie rheumatoider Arthritis, Multipler Sklerose, entzündlichen Darmerkrankungen und Psoriasis als wichtiger Pathomechanismus, der an der Verschlimmerung von Entzündungssymptomen und der Chronifizierung der Krankheit beteiligt ist, beschrieben...
July 2015: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/26081381/-burning-vulva-significance-of-surgery-in-inflammatory-and-precancerous-vulvar-pathologies
#7
REVIEW
Gian-Piero Ghisu, Daniel Fink
Vuval pathologies manifested by allodynia and burning sensations can be due to infection, inflammatory dermatoses or other causes. Infective as well as certain inflammatory diseases, e.g. drug eruptions, allergic eczemas, irritative dermatitis/vulvitis, Behcet's Syndrome and pemphigus/pemphigoid usually respond well to conservative treatment. The category of inflammatory diseases also contains pathologies that in certain circumstances do require a surgical intervention, e.g. Lichen ruber planus/Lichen sclerosus, Condyloma, scars, premalignant lesions (VIN, genital M...
June 17, 2015: Praxis
https://www.readbyqxmd.com/read/24098463/expression-of-human-endogenous-retrovirus-w-including-syncytin-1-in-cutaneous-t-cell-lymphoma
#8
Pilvi Maliniemi, Michelle Vincendeau, Jens Mayer, Oliver Frank, Sonja Hahtola, Leena Karenko, Emilia Carlsson, Francois Mallet, Wolfgang Seifarth, Christine Leib-Mösch, Annamari Ranki
The pathomechanism of mycosis fungoides (MF), the most common type of primary cutaneous T-cell lymphomas (CTCLs) and a malignancy of non-recirculating, skin-resident T-cells, is unknown albeit underlying viral infections have been sought for. Human endogenous retroviruses (HERVs) are ancient retroviral sequences in the human genome and their transcription is often deregulated in cancers. We explored the transcriptional activity of HERV sequences in a total of 34 samples comprising MF and psoriasis skin lesions, as well as corresponding non-malignant skin using a retrovirus-specific microarray and quantitative RT-PCR...
2013: PloS One
https://www.readbyqxmd.com/read/23948733/oral-esophageal-and-cutaneous-lichen-ruber-planus-controlled-with-alitretinoin-case-report-and-review-of-the-literature
#9
REVIEW
Antonios G A Kolios, Ewerton Marques Maggio, Christoph Gubler, Antonio Cozzio, Reinhard Dummer, Lars E French, Alexander A Navarini
BACKGROUND: Therapy-resistant lichen planus (LP) can be a challenging condition for dermatologists. There are some case reports about successful treatments with alitretinoin of cutaneous and oral, but not of esophageal LP. OBJECTIVE: We present the unique case of a patient with cutaneous, oral and esophageal LP which was refractory to classical treatment options (topical clobetasol propionate and pimecrolimus, intramuscular triamcinolone acetonide); because of systemic side effects the patient did not tolerate systemic acitretin dosed up to 25 mg daily...
2013: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/23573742/-patient-with-lichen-ruber-planus-how-should-it-be-treated
#10
H S Füessl, P Stiefelhagen
No abstract text is available yet for this article.
February 7, 2013: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/22760935/incidental-diagnosis-of-a-retroperitoneal-schwannoma-in-a-patient-with-chronic-leukemia-undergoing-prostatic-biopsy
#11
Domenico Autieri, Antonio Luigi Pastore, Luigi Silvestri, Antonino Leto, Andrea Ripoli, Giovanni Palleschi, Natale Porta, Vincenzo Petrozza, Antonio Carbone
We present a case of retroperitoneal schwannoma incidentally diagnosed in a patient undergoing surgical drainage of a pelvic abscess as a complication of a prostatic biopsy. A 50-year-old male, suffering from lymphatic leukemia, came to our observation due to lichen ruber planus and ejaculatory pain. The patient underwent a trans-perineal ultrasound-guided biopsy of the right seminal vesicle and of a hypoechoic area documented by ultrasonography. 48 hours after the procedure, the patient had developed: cold sores, shortness of breath with dyspnea, and high fever (40°C)...
2012: Urologia
https://www.readbyqxmd.com/read/21834467/-variations-of-hbd-2-and-tlr-2-gene-expression-in-patients-presenting-with-lichen-ruber-planus-under-effect-of-ultraviolet-irradiation
#12
A A Shakhnovich, L S Kruglova
The combination of narrow-band range UV-A (311 nm) and middle/broad-band UV-B (320-400 nm) irradiation was shown to significantly reduce manifestations of objective and subjective symptoms in the patients presenting with lichen ruber planus. Moreover, it promoted elimination ofdisbalance between characteristics of congenital immunity and normalization of HBD-2 and TLR-2 gene expression.
May 2011: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/21309502/a-case-of-lichen-ruber-planus-in-a-patient-with-familial-multiple-sclerosis
#13
J Sepić, S Ristić, O Perković, V Brinar, J Lipozencić, M Crnić-Martinović, N Starcević Cizmarević, D Janko Labinac, M Kapović, B Peterlin
Multiple sclerosis and lichen ruber planus are clinically and histologically distinct complex disorders of putative autoimmune aetiology that are fairly commonly observed in isolation but rarely found in combination. Only two previous reports have described lichen skin disorders in association with multiple sclerosis. The present report describes the case of a 51-year-old Caucasian woman exhibiting both familial multiple sclerosis and lichen ruber planus. This combination may have occurred by chance or it might imply that these disorders share common mechanisms in their pathogenesis...
September 2010: Journal of International Medical Research
https://www.readbyqxmd.com/read/21107806/-the-female-external-genitalia-pathologic-findings-and-first-steps-in-treatment
#14
C Goldnau, A Köninger, R Kimmig
Symptoms of diseases of the female external genitalia are often expressed in pruritus and burning pain. To accomplish a targeted differential diagnosis an exact knowledge of anatomy is essential. An accurate anamnesis, a detailed inspection, and conducting a biopsy or microbiological smear lead to the correct diagnosis. Lichen sclerosus et atrophicus is the most common non-neoplastic disease of the vulva. This should be distinguished from amongst others lichen ruber planus, psoriasis, contact dermatitis of the vulva, or infectious diseases like condylomata acuminata, herpes genitalis, or mycosis...
December 2010: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/21026331/exanthema-resembling-lichen-ruber-during-treatment-with-neosalvarsan
#15
B SYLVEST
No abstract text is available yet for this article.
January 1946: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/21000212/lichen-ruber-moniliformis-kaposi
#16
F PINKUS
No abstract text is available yet for this article.
October 1946: Archives of Dermatology and Syphilology
https://www.readbyqxmd.com/read/20917027/lichen-ruber-moniliformis-morbus-moniliformis-lichenoides-myx%C3%A5-dema-moniliforme
#17
P B Mumford, H W Barber
No abstract text is available yet for this article.
April 1943: Proceedings of the Royal Society of Medicine
https://www.readbyqxmd.com/read/20767182/a-rare-form-of-lichen-ruber-planus
#18
C H Cattle
No abstract text is available yet for this article.
June 13, 1914: British Medical Journal (1857-1980)
https://www.readbyqxmd.com/read/20746189/clinical-lecture-on-lichen-ruber-of-hebra
#19
T Fox
No abstract text is available yet for this article.
April 15, 1871: British Medical Journal (1857-1980)
https://www.readbyqxmd.com/read/20671948/possible-implication-of-local-immune-response-in-darier-s-disease-an-immunohistochemical-characterization-of-lesional-inflammatory-infiltrate
#20
Clelia Miracco, Francesco Pietronudo, Vasileios Mourmouras, Michele Pellegrino, Monica Onorati, Maria Grazia Mastrogiulio, Luca Cantarini, Pietro Luzi
Cell-mediated immunity is considered to be normal in Darier's Disease (DD), an inherited skin disorder complicated by skin infections. To date, there are no investigations on the local inflammatory infiltrate in DD skin lesions. In this immunohistochemical study we characterized and quantified it, making comparisons with two other inflammatory skin disorders, that is, pemphigus vulgaris (PV) and lichen ruber planus (LRP), and with the normal skin (NSk). We found a significant (P < .05) decrease of CD1a+ Langerhans cells (LCs) in DD, compared to PV, LRP, and NSk, and of CD123+ plasmacytoid dendritic cells (pDCs), compared to PV and LRP...
2010: Mediators of Inflammation
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