keyword
MENU ▼
Read by QxMD icon Read
search

Imc

keyword
https://www.readbyqxmd.com/read/27856523/beyond-histological-remission-intramucosal-calprotectin-as-a-potential-predictor-of-outcomes-in-ulcerative-colitis
#1
Marianne Guirgis, Emily Wendt, Lai Mun Wang, Alissa Walsh, Daniel Burger, Robert V Bryant, Alex Kent, Rebecca Adamson, Oliver Brain, Simon P L Travis, Satish Keshav
BACKGROUND AND AIMS: Histological remission and low faecal calprotectin are positive prognostic factors in ulcerative colitis [UC]. Intramucosal calprotectin [iMC], which can be readily determined by immunohistochemistry, has not so far been evaluated as a predictor of outcome in UC. We aimed to investigate the relationship between iMC and clinical, endoscopic, and histological measures of remission in UC, and the independent prognostic value of iMC. METHODS: Ambulant patients with UC were recruited for a study comparing clinical activity indices...
November 14, 2016: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/27845697/-efficacy-and-safety-of-bilateral-rirs-for-renal-lithiasis
#2
José Luis Bauzá, Enrique Pieras, Valentí Tubau, Arnau Sabaté, Jordi Guimerá, Ana Martínez, Juan Ferrutxe, Pedro Pizá
OBJECTIVES: We present our experience in single-stage bilateral retrograde intrarenal surgery (RIRS), analyzing the stone free rate (SFR), surgical time, hospital stay, pre- and post procedure creatinine, stone composition and complications. METHODS: Between April 2012 and February 2016, 24 RIRS were carried out in 12 patients with bilateral renal stones. Patients were 9 men and 3 women with a median age of 47.5 (range:55),IMC: 23.59 (range: 12.5). RESULTS: Mean number of stones per renal unit was 2...
November 2016: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/27803680/survey-satisficing-inflates-stereotypical-responses-in-online-experiment-the-case-of-immigration-study
#3
Asako Miura, Tetsuro Kobayashi
Though survey satisficing, grudging cognitive efforts required to provide optimal answers in the survey response process, poses a serious threat to the validity of online experiments, a detailed explanation of the mechanism has yet to be established. Focusing on attitudes toward immigrants, we examined the mechanism by which survey satisficing distorts treatment effect estimates in online experiments. We hypothesized that satisficers would display more stereotypical responses than non-satisficers would when presented with stereotype-disconfirming information about an immigrant...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27797971/an-open-label-dose-escalation-phase-i-study-of-anti-tyrp1-monoclonal-antibody-imc-20d7s-for-patients-with-relapsed-or-refractory-melanoma
#4
Danny N Khalil, Michael A Postow, Nageatte Ibrahim, Dale L Ludwig, Jan Cosaert, Siva Rama Prasad Kambhampati, Shande Tang, Dmitri Grebennik, John Sae Wook Kauh, Heinz-Josef Lenz, Keith T Flaherty, F Stephen Hodi, Donald P Lawrence, Jedd D Wolchok
PURPOSE: Tyrosinase-related protein-1 (TYRP1) is a transmembrane glycoprotein that is specifically expressed in melanocytes and melanoma cells. Preclinical data suggest that mAbs targeting TYRP1 confer antimelanoma activity. IMC-20D7S is a recombinant human IgG1 mAb targeting TYRP1. Here, we report the first-in-human phase I/Ib trial of IMC-20D7S. EXPERIMENTAL DESIGN: The primary objective of this study was to establish the safety profile and the MTD of IMC-20D7S...
November 1, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/27775181/comparison-of-telomere-length-and-insulin-like-growth-factor-binding-protein-7-promoter-methylation-between-breast-cancer-tissues-and-adjacent-normal-tissues-in-turkish-women
#5
Zehra Kaya, Mustafa Akkiprik, Sevgi Karabulut, Irem Peker, Gokce Gullu Amuran, Tolga Ozmen, Bahadır M Gulluoglu, Handan Kaya, Ayse Ozer
BACKGROUND: Both insulin-like growth factor-binding protein 7 (IGFBP7) and telomere length (TL) are associated with proliferation and senescence of human breast cancer. This study assessed the clinical significance of both TL and IGFBP7 methylation status in breast cancer tissues compared with adjacent normal tissues. We also investigated whether IGFBP7 methylation status could be affecting TL. METHODS: Telomere length was measured by quantitative PCR to compare tumors with their adjacent normal tissues...
October 24, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27773288/effect-of-ultrasonic-vibration-time-on-the-cu-sn-ag-cu-cu-joint-soldered-by-low-power-high-frequency-ultrasonic-assisted-reflow-soldering
#6
Ai Ting Tan, Ai Wen Tan, Farazila Yusof
Techniques to improve solder joint reliability have been the recent research focus in the electronic packaging industry. In this study, Cu/SAC305/Cu solder joints were fabricated using a low-power high-frequency ultrasonic-assisted reflow soldering approach where non-ultrasonic-treated samples were served as control sample. The effect of ultrasonic vibration (USV) time (within 6s) on the solder joint properties was characterized systematically. Results showed that the solder matrix microstructure was refined at 1...
January 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/27762585/seven-years-of-radionuclide-laboratory-at-imc-important-achievements
#7
M Hrubý, J Kučka, J Pánek, P Štěpánek
For many important research topics in polymer science the use of radionuclides brings significant benefits concerning nanotechnology, polymer drug delivery systems, tissue engineering etc. This contribution describes important achievements of the radionuclide laboratory at Institute of Macromolecular Chemistry of the Academy of Sciences of the Czech Republic (IMC) in the area of polymers for biomedical applications. Particular emphasis will be given to water-soluble polymer carriers of radionuclides, thermoresponsive polymer radionuclide carriers, thermoresponsive polymers for local brachytherapy, polymer scaffolds modified with (radiolabeled) peptides and polymer copper chelators for the therapy of Wilson´s disease...
October 20, 2016: Physiological Research
https://www.readbyqxmd.com/read/27759972/estado-nutricional-y-etapas-de-cambio-comportamental-frente-a-la-actividad-f%C3%A3-sica-en-ni%C3%A3-os-y-adolescentes-de-bogot%C3%A3-colombia-estudio-fuprecol
#8
Luisa Fernanda Rodríguez-Villalba, Robinson Ramírez-Vélez, Jorge Enrique Correa-Bautista
Objetivo: el propósito del estudio fue relacionar la etapa en el cambio en el comportamiento frente a la actividad física y el estado nutricional en escolares de Bogotá, Colombia, pertenecientes al estudio FUPRECOL.Método: se trata de un estudio transversal, realizado en 8.000 niños y adolescentes de entre 9 y 17 años, pertenecientes a 24 instituciones educativas. Se aplicó de manera autodiligenciada el cuestionario de cambio de comportamiento en función de la intención de realizar actividad física (CCC-FUPRECOL) y se midió el peso y la estatura para determinar el estado nutricional con el índice de masa corporal (IMC)...
September 20, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27759970/ingesta-de-energ%C3%A3-a-y-nutrientes-en-ni%C3%A3-os-de-2-4-a%C3%A3-os-que-asisten-al-programa-%C3%A2-buen-comienzo%C3%A2-medell%C3%A3-n-colombia-energy-and-nutrients-intake-in-childre
#9
Natalia Inés Ledesma Ríos, Diana María Sepúlveda Herrera, Diana Liseth Cárdenas Sánchez, Luz Mariela Manjarrés Correa
Introducción: a escala mundial y nacional se reporta una alta prevalencia de sobrepeso y obesidad en menores de 5 años. La etiología es multifactorial, pero factores ambientales como sedentarismo y el progresivo deterioro de la alimentación promueven el exceso de peso y conllevan a mayor riesgo de enfermedades crónicas no transmisibles en temprana edad.Objetivo: describir la ingesta de alimentos, energía y nutrientes en los niños de 2-4 años con obesidad y eutróficos del programa "Buen Comienzo".Método: estudio de corte con 111 niños con obesidad clasificada según IMC >3 DE, que fueron pareados por sexo, edad y tipo de atención con un niño clasificado con estado nutricional normal...
September 20, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27759969/bajos-niveles-de-rendimiento-f%C3%A3-sico-vo2-max-y-elevada-prevalencia-de-obesidad-en-escolares-de-9-a-14-a%C3%A3-os-de-edad
#10
Felipe Caamaño Navarrete, Pedro Delgado Floody, Daniel Jerez Mayorga, Aldo Osorio Poblete
Introducción: bajos niveles de actividad física, moderada y vigorosa, son un factor de riesgo conductual importante en la obesidad en niños.Objetivo: el objetivo del estudio fue determinar el estado nutricional y la condición física de escolares, comparando los resultados obtenidos por género, obesidad y rendimiento físico.Material y métodos:578 escolares: 308 hombres de 11,22 ± 1,93 años y 270 mujeres de 10,93 ± 1,92 años participaron en la investigación. Fueron evaluados: índice de masa corporal (IMC), porcentaje de masa grasa (%MG), contorno de cintura (CC), razón cintura-estatura (RCE) y rendimiento físico según los test del Estudio Nacional de Educación Física de la Agencia de Calidad de la Educación de Chile...
September 20, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27759773/prognostic-factors-and-survival-analysis-in-esophageal-carcinoma
#11
Francisco Tustumi, Cintia Mayumi Sakurai Kimura, Flavio Roberto Takeda, Rodrigo Hideki Uema, Rubens Antônio Aissar Salum, Ulysses Ribeiro-Junior, Ivan Cecconello
Background: Despite recent advances in diagnosis and treatment, esophageal cancer still has high mortality. Prognostic factors associated with patient and with disease itself are multiple and poorly explored. Aim: Assess prognostic variables in esophageal cancer patients. Methods: Retrospective review of all patients with esophageal cancer in an oncology referral center. They were divided according to histological diagnosis (444 squamous cell carcinoma patients and 105 adenocarcinoma), and their demographic, pathological and clinical characteristics were analyzed and compared to clinical stage and overall survival...
July 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27737391/development-of-height-and-body-mass-index-after-pediatric-kidney-transplantation-experience-of-the-nephrology-pediatric-service-at-hcfmrp-usp-2005-2014
#12
Elaine Hillesheim, Valéria Laguna Salomão Ambrósio, Inalda Facincani
Introduction: Chronic kidney disease in children often determines poor nutritional status. Although renal transplantation (RTx) resolves endocrine and metabolic disorders, growth continues to be suboptimal and excessive weight gain may result in obesity. Objectives: Evaluating the development of height and body mass index in renal transplanted children and adolescents and identifying associated factors with final nutritional status. Methods: We reviewed the medical records of 17 patients with regular follow-ups up to 24 months after RTx...
July 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/27737377/stages-of-change-of-behavior-in-women-on-a-multi-professional-program-for-treatment-of-obesity
#13
Cheila Aparecida Bevilaqua, Sandra Marisa Pelloso, Sonia Silva Marcon
Objective: to ascertain the effectiveness of an intervention program in relation to anthropometric measurements and stage of readiness for behavioral change in women with excess weight. Methods: the intervention group (IG) was made up of 13 women, and the control group (CG), by 20. The intervention lasted 16 weeks, and included the practice of guided physical activity three times a week, and health education once a week. The application of the questionnaire on stage of readiness for behavioral change, and the anthropometric evaluations, were undertaken at two points - before and after the period of intervention...
October 10, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27728798/senescence-and-cancer-in-the-name-of-immunosuppression
#14
Susana Llanos, Manuel Serrano
Senescent cells and cancer cells recruit immunosuppressive myeloid cells. In this issue of Cancer Cell, Eggert et al. report that senescent cells recruit immature myeloid cells (iMCs) through the secretion of the CCL2 cytokine and that these iMCs have pro- or anti-tumorigenic activities, depending on the cellular context.
October 10, 2016: Cancer Cell
https://www.readbyqxmd.com/read/27696623/novel-insights-into-the-composition-and-function-of-the-toxoplasma-imc-sutures
#15
Allan L Chen, Andy S Moon, Hannah N Bell, Amy S Huang, Ajay A Vashisht, Justin Y Toh, Andrew H Lin, Santhosh M Nadipuram, Elliot W Kim, Charles P Choi, James A Wohlschlegel, Peter J Bradley
The Toxoplasma inner membrane complex (IMC) is a specialized organelle underlying the parasite's plasma membrane that consists of flattened rectangular membrane sacs that are sutured together and positioned atop a supportive cytoskeleton. We have previously identified a novel class of proteins localizing to the transverse and longitudinal sutures of the IMC, which we named ISCs. Here we have used proximity-dependent biotin identification (BioID) at the sutures to better define the composition of this IMC subcompartment...
October 1, 2016: Cellular Microbiology
https://www.readbyqxmd.com/read/27695325/surface-biofunctionalized-cds-and-zns-quantum-dot-nanoconjugates-for-nanomedicine-and-oncology-to-be-or-not-to-be-nanotoxic
#16
Alexandra Ap Mansur, Herman S Mansur, Sandhra M de Carvalho, Zélia Ip Lobato, Maria Imc Guedes, Maria F Leite
Herein, for the first time, we demonstrated that novel biofunctionalized semiconductor nanomaterials made of Cd-containing fluorescent quantum dot nanoconjugates with the surface capped by an aminopolysaccharide are not biologically safe for clinical applications. Conversely, the ZnS-based nanoconjugates proved to be noncytotoxic, considering all the parameters investigated. The results of in vitro cytotoxicity were remarkably dependent on the chemical composition of quantum dot (CdS or ZnS), the nature of the cell (human cancerous and embryonic types), and the concentration and time period of exposure to these nanomaterials, caused by the effects of Cd(2+) on the complex nanotoxicity pathways involved in cellular uptake...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27692620/solubility-advantage-and-disadvantage-of-pharmaceutical-amorphous-solid-dispersions
#17
Siyuan Huang, Chen Mao, Robert O Williams, Chia-Yi Yang
The solubility of a drug is ultimately governed by its chemical potential as it is present in the undissolved solute. For a pharmaceutical amorphous solid dispersion (ASD), its solubility depends on the state and composition of the undissolved solute when the ASD is equilibrated with water. Concerning the undissolved solute phase that can contain up to 3 components (drug, polymer, and water), we developed a complete thermodynamic model to calculate the chemical potential of a drug in the multicomponent, amorphous system...
September 28, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27688716/successful-implementation-of-a-multicountry-clinical-surveillance-and-data-collection-system-for-ebola-virus-disease-in-west-africa-findings-and-lessons-learned
#18
Reshma Roshania, Michaela Mallow, Nelson Dunbar, David Mansary, Pranav Shetty, Taralyn Lyon, Kacey Pham, Matthew Abad, Erin Shedd, Anh-Minh A Tran, Sarah Cundy, Adam C Levine
BACKGROUND: The 2014 outbreak of Ebola virus disease (EVD) in West Africa was the largest ever recorded. Starting in September 2014, International Medical Corps (IMC) managed 5 Ebola treatment units (ETUs) in Liberia and Sierra Leone, which cumulatively cared for about 2,500 patients. We conducted a retrospective cohort study of patient data collected at the 5 ETUs over 1 year of operations. METHODS: To collect clinical and epidemiological data from the patient care areas, each chart was either manually copied across the fence between the high-risk zone and low-risk zone, imaged across the fence, or imaged in the high-risk zone...
September 28, 2016: Global Health, Science and Practice
https://www.readbyqxmd.com/read/27683788/the-role-of-metabolic-surgery-for-patients-with-obesity-grade-i-and-type-2-diabetes-not-controlled-clinically
#19
Josemberg Campos, Almino Ramos, Thomaz Szego, Bruno Zilberstein, Heládio Feitosa, Ricardo Cohen
Introduction: Even considering the advance of the medical treatment in the last 20 years with new and more effective drugs, the outcomes are still disappointing as the control of obesity and type 2 Diabetes Mellitus (T2DM) with a large number of patients under the medical treatment still not reaching the desired outcomes. Objective: To present a Metabolic Risk Score to better guide the surgical indication for T2DM patients with body mass index (BMI) where surgery for obesity is still controversial...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27683786/endoscopic-sleeve-gastroplasty-minimally-invasive-therapy-for-primary-obesity-treatment
#20
Manoel Dos Passos Galvão-Neto, Eduardo Grecco, Thiago Ferreira de Souza, Luiz Gustavo de Quadros, Lyz Bezerra Silva, Josemberg Marins Campos
Background: Less invasive and complex procedures have been developed to treat obesity. The successful use of Endoscopic Sleeve Gastroplasty using OverStitch(r) (Apollo Endosurgery, Austin, Texas, USA) has been reported in the literature. Aim: Present technical details of the procedure and its surgical/ endoscopic preliminary outcome. Method: The device was used to perform plications along the greater curvature of the stomach, creating a tubulization similar to a sleeve gastrectomy...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
keyword
keyword
74056
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"