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https://www.readbyqxmd.com/read/28327655/thin-film-metallic-glass-an-effective-diffusion-barrier-for-se-doped-agsbte2-thermoelectric-modules
#1
Chia-Chi Yu, Hsin-Jay Wu, Ping-Yuan Deng, Matthias T Agne, G Jeffrey Snyder, Jinn P Chu
The thermal stability of joints in thermoelectric (TE) modules, which are degraded during interdiffusion between the TE material and the contacting metal, needs to be addressed in order to utilize TE technology for competitive, sustainable energy applications. Herein, we deposit a 200 nm-thick Zr-based thin-film metallic glass (TFMG), which acts as an effective diffusion barrier layer with low electrical contact resistivity, on a high-zT Se-doped AgSbTe2 substrate. The reaction couples structured with TFMG/TE are annealed at 673 K for 8-360 hours and analyzed by electron microscopy...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28326102/impacted-maxillary-canine-prevalence-and-its-association-with-other-dental-anomalies-in-a-mexican-population
#2
José Rubén Herrera-Atoche, María Del Rosario Agüayo-de-Pau, Mauricio Escoffié-Ramírez, Fernando Javier Aguilar-Ayala, Bertha Arelly Carrillo-Ávila, Marina Eduviges Rejón-Peraza
Objective. We quantified the prevalence of impacted maxillary canines (IMC) and their association with other dental anomalies (DAs). Materials and Methods. A retrospective study was done with 860 patients 12 to 39 years of age. The prevalence of IMC was calculated and compared by sex. The sample was divided into a control group and an impaction group, and the prevalence was calculated in both for a series of anomalies: agenesis, supernumerary teeth, shape anomalies of the upper laterals (microdontia, peg and barrel shape, and talon cusp), fusion, gemination, other impacted teeth, transposition, and amelogenesis imperfecta...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28325526/enhanced-imc-based-pid-controller-design-for-non-minimum-phase-nmp-integrating-processes-with-time-delays
#3
K Ghousiya Begum, A Seshagiri Rao, T K Radhakrishnan
Internal model control (IMC) with optimal H2 minimization framework is proposed in this paper for design of proportional-integral-derivative (PID) controllers. The controller design is addressed for integrating and double integrating time delay processes with right half plane (RHP) zeros. Blaschke product is used to derive the optimal controller. There is a single adjustable closed loop tuning parameter for controller design. Systematic guidelines are provided for selection of this tuning parameter based on maximum sensitivity...
March 18, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28317275/synthesis-of-%C3%AE-tubulin-occurs-within-chromatoid-body-of-round-spermatids
#4
Yuki Fujii, Hideaki Fujita, Sadaki Yokota
mRNAs for proteins required in elongated spermatids are considered to be transcribed at an early stage and stored in cytoplasm, presumably in chromatoid body (CB), one type of nuage component (a unique structure that appears and disappears during spermatogenesis), because transcription of genes does not occur at late stages. In elongated spermatids, a large amount of tubulin molecules is required to form microtubules of manchette and flagellum. To investigate the possible role of CB in translation of tubulin mRNA, we performed immunofluorescence and immunoelectron microscopic localization studies of α- and β-tubulin in rat spermatogenic cells...
March 20, 2017: Cytoskeleton
https://www.readbyqxmd.com/read/28285953/predictive-value-of-different-covariates-influencing-pregnancy-rate-following-intrauterine-insemination-with-homologous-semen-a-prospective-cohort-study
#5
Annelies Thijssen, An Creemers, Wim Van der Elst, Eva Creemers, Eva Vandormael, Nathalie Dhont, Willem Ombelet
The aim was to examine the value of different covariates in the prediction of intrauterine insemination (IUI) success. Between July 2011 and September 2015, data from 1401 IUI cycles with homologous semen in 556 couples were collected prospectively, by questionnaire, in a tertiary referral infertility centre. Statistical analysis was performed using generalized estimating equations (GEEs). GEEs were used instead of an ordinary logistic regression model to take into account the correlation between observations from the same person...
February 24, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28260944/a-famciclovir-celecoxib-combination-treatment-is-safe-and-efficacious-in-the-treatment-of-fibromyalgia
#6
William L Pridgen, Carol Duffy, Judy F Gendreau, R Michael Gendreau
OBJECTIVE: Infections and other stressors have been implicated in the development of fibromyalgia. We hypothesized that these stressors could result in recurrent reactivations of latent herpes virus infections, which could lead to the development of fibromyalgia. This study evaluated a famciclovir + celecoxib drug combination (IMC-1), active against suspected herpes virus reactivation and infection, for the treatment of fibromyalgia. METHODS: A total of 143 fibromyalgia patients were enrolled at 12 sites in a 16-week, double-blinded, placebo-controlled proof-of-concept trial...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28255809/unplanned-irradiation-of-internal-mammary-lymph-nodes-in-breast-cancer
#7
Gul Kanyilmaz, Meryem Aktan, Mehmet Koc, Hikmettin Demir, Lütfi Saltuk Demir
AIMS: To evaluate the incidental dose to the internal mammary chain (IMC) in patients treated with three-dimensional conformal radiotherapy, to estimate the predictors affecting the magnitude of IMC receiving dose and to determine the predictive role of clinical parameters on survival. MATERIALS AND METHODS: Between 2009 and 2015, 348 patients undergoing RT for breast cancer were retrospectively analyzed. All patients underwent our department's routine procedure for breast cancer...
March 3, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28244796/biomarcadores-de-pron%C3%A3-stico-modificables-nutricionalmente-en-el-paciente-con-c%C3%A3-ncer-colorrectal-tras-el-diagn%C3%A3-stico-de-la-enfermedad
#8
Beatriz Escudero Paniagua, Alicia Aguilar-Martínez, Begoña Manuel Keenoy
Introducción: el cáncer colorrectal (CCR) es el segundo cáncer más frecuente en el mundo occidental, de tal manera que se diagnostican cerca de 1 millón de casos nuevos por año. La tasa de supervivencia de pacientes con CCR varía ampliamente, aun entre pacientes con el mismo tumor histológico. Esto posiblemente es debido al impacto de los factores ambientales sobre el desarrollo tumoral. Dentro de estos factores, destaca la dieta. Se conoce que la nutrición puede modificar el riesgo de padecer CCR...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28244787/impulsividad-y-conducta-alimentaria-en-varones
#9
Ignacio Jáuregui-Lobera, María José Santiago
Introducción: la impulsividad es un rasgo de personalidad relacionado con el control de la conducta y de las emociones y que se observa en diferentes alteraciones psicopatológicas, entre ellas las referidas a la conducta alimentaria. Objetivo: el objetivo del presente trabajo fue analizar la relación entre la infl uencia del modelo estético corporal, la conducta alimentaria (y riesgo de patología específi ca), el IMC y la impulsividad.Método: fueron incluidos en el estudio 178 varones con una edad media de 20,18 ± 2,48 años...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28244784/evaluaci%C3%A3-n-del-consumo-de-alimentos-de-una-poblaci%C3%A3-n-de-estudiantes-universitarios-y-su-relaci%C3%A3-n-con-el-perfil-acad%C3%A3-mico
#10
Gema Muñoz de Mier, María Del Carmen Lozano Estevan, Carlos Santiago Romero Magdalena, Javier Pérez de Diego, Pablo Veiga Herreros
Objetivo: el propósito de este estudio ha sido evaluar la calidad de la alimentación de los estudiantes de la Universidad Alfonso X El Sabio (Madrid) y establecer si tener una formación específica sobre temas de nutrición produce efectos positivos en los comportamientos alimentarios. Métodos: la muestra estuvo formada por 390 estudiantes, 72,63% de Ciencias de la Salud (CS) y 27,37% de otras carreras (No CS), con edades comprendidas entre 18 y 25 años. A través de un cuestionario se recabó información sobre frecuencia de consumo de alimentos...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28244783/diferencias-entre-la-prevalencia-de-obesidad-y-exceso-de-peso-estimadas-con-datos-declarados-o-por-medici%C3%A3-n-directa-en-adultos-de-la-comunidad-valenciana
#11
Raquel Jiménez-Talamantes, Jennifer Rizk Hernández, Joan Quiles Izquierdo
Introducción:la evaluación de la obesidad en las encuestas de salud contempla el estudio de las características corporales por medición o por declaración. Según el método utilizado puede producirse una estimación diferente de la frecuencia de este problema.Objetivos: medir las discrepancias en las estimaciones de prevalencia de obesidad y exceso de peso realizadas con datos declarados con respecto a los medidos en una encuesta poblacional.Métodos: estudio transversal de una muestra de 1.153 sujetos adultos donde se compararon los datos de peso y talla declarados y medidos mediante la correlación de Pearson (r)...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28244778/las-medidas-antropom%C3%A3-tricas-como-indicadores-predictivos-de-riesgo-metab%C3%A3-lico-en-una-poblaci%C3%A3-n-mexicana
#12
Teresa Domínguez-Reyes, Irma Quiroz-Vargas, Aralia Berenice Salgado-Bernabé, Lorenzo Salgado-Goytia, José Francisco Muñoz-Valle, Isela Parra-Rojas
Introducción: actualmente se considera que la acumulación de grasa corporal a nivel central se asocia con la presencia de hipertrigliceridemia, hipertensión arterial y diabetes. El índice de masa corporal (IMC) se ha utilizado para identificar la obesidad en la población general, pero no permite determinar la distribución de la grasa corporal, por lo que se pueden utilizar otras medidas antropométricas para evaluar la adiposidad y determinar su relación con la presencia de alteraciones metabólicas que presentan las personas con exceso de peso...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28244777/obesidad-y-riesgo-de-infarto-de-miocardio-en-una-muestra-de-varones-europeos-el-%C3%A3-ndice-cintura-cadera-sesga-el-riesgo-real-de-la-obesidad-abdominal
#13
Ángel Martín Castellanos, María Dolores Cabañas Armesilla, Francisco Javier Barca Durán, Pedro Martín Castellanos, José Javier Gómez Barrado
Introducción: la obesidad es un factor de riesgo asociado al infarto de miocardio aunque el índice cintura-cadera ha mostrado mayor poder predictivo.Objetivo: análisis antropométrico Receiver Operating Characteristic(ROC) en infartados para identificar la fuerza discriminatoria de mediciones, obesidad, ratios cintura-cadera, ratios cintura-talla e índice de conicidad.Métodos: estudio caso-control de infarto miocárdico en varones europeos. Ciento doce casos/112 controles de 30-74 años fueron reclutados...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28244772/asociaci%C3%A3-n-de-la-percepci%C3%A3-n-materna-del-peso-del-hijo-y-estilos-maternos-de-alimentaci%C3%A3-n-infantil
#14
Yolanda Flores-Peña, América Acuña-Blanco, Velia M Cárdenas-Villarreal, Marily D Amaro-Hinojosa, María E Pérez-Campa, Jesús R Elenes-Rodríguez
Introducción: las madres no reconocen cuando su hijo presenta sobrepeso-obesidad (SP-OB) y existe evidencia de relación entre esta percepción (PMPH) no adecuada y el estilo materno de alimentación infantil (EMAI).Objetivos: a) evaluar la confiabilidad del Cuestionario Estilos de Alimentación del Cuidador (CFSQ); b) verificar la asociación entre la PMPH y el estado nutricio del hijo; c) describir el EMAI; d) verificar diferencias entre el EMAI y el IMC del hijo; e) verificar la asociación entre la PMPH y los EMAI...
February 1, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28235596/outcomes-after-liquid-nitrogen-spray-cryotherapy-in-barrett-s-esophagus-associated-high-grade-dysplasia-and-intramucosal-adenocarcinoma-5-year-follow-up
#15
Fariha H Ramay, Qingping Cui, Bruce D Greenwald
BACKGROUND: Liquid nitrogen spray cryotherapy (LNSCT) has been shown to be a safe, well-tolerated, and effective therapy for Barrett's esophagus (BE)-associated high grade dysplasia (BE-HGD) and intramucosal adenocarcinoma (IMC). Long-term follow-up is lacking. AIMS: The authors' aim was to assess the efficacy, durability, and rate of neoplastic progression after LNSCT in BE-HGD/IMC at 3 and 5 years. METHODS: In this single-center, retrospective study drawn from a prospective database, patients with BE-HGD/IMC of any length treated with LNSCT were followed with surveillance endoscopy with biopsy for 3 to 5 years...
February 21, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28220862/induction-of-hair-follicle-dermal-papilla-cell-properties-in-human-induced-pluripotent-stem-cell-derived-multipotent-lngfr-thy-1-mesenchymal-cells
#16
Ophelia Veraitch, Yo Mabuchi, Yumi Matsuzaki, Takashi Sasaki, Hironobu Okuno, Aki Tsukashima, Masayuki Amagai, Hideyuki Okano, Manabu Ohyama
The dermal papilla (DP) is a specialised mesenchymal component of the hair follicle (HF) that plays key roles in HF morphogenesis and regeneration. Current technical difficulties in preparing trichogenic human DP cells could be overcome by the use of highly proliferative and plastic human induced pluripotent stem cells (hiPSCs). In this study, hiPSCs were differentiated into induced mesenchymal cells (iMCs) with a bone marrow stromal cell phenotype. A highly proliferative and plastic LNGFR(+)THY-1(+) subset of iMCs was subsequently programmed using retinoic acid and DP cell activating culture medium to acquire DP properties...
February 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28220071/efficient-computation-of-functional-brain-networks-toward-real-time-functional-connectivity
#17
Juan García-Prieto, Ricardo Bajo, Ernesto Pereda
Functional Connectivity has demonstrated to be a key concept for unraveling how the brain balances functional segregation and integration properties while processing information. This work presents a set of open-source tools that significantly increase computational efficiency of some well-known connectivity indices and Graph-Theory measures. PLV, PLI, ImC, and wPLI as Phase Synchronization measures, Mutual Information as an information theory based measure, and Generalized Synchronization indices are computed much more efficiently than prior open-source available implementations...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/28200030/a-phase-ii-study-of-a-human-anti-pdgfr%C3%AE-monoclonal-antibody-olaratumab-imc-3g3-in-previously-treated-patients-with-unresectable-and-or-metastatic-gastrointestinal-stromal-tumors
#18
A J Wagner, H Kindler, H Gelderblom, P Schöffski, S Bauer, P Hohenberger, H-G Kopp, J A Lopez-Martin, M Peeters, P Reichardt, A Qin, J Nippgen, R L Ilaria, P Rutkowski
No abstract text is available yet for this article.
February 14, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28161886/phase-1-study-of-narnatumab-an-anti-ron-receptor-monoclonal-antibody-in-patients-with-advanced-solid-tumors
#19
Patricia M LoRusso, Mrinal Gounder, Shadia I Jalal, Valérie André, Siva Rama Prasad Kambhampati, Nick Loizos, Jennifer Hall, Timothy R Holzer, Aejaz Nasir, Jan Cosaert, John Kauh, E Gabriela Chiorean
Purpose Macrophage-stimulating 1-receptor (RON) is expressed on macrophages, epithelial cells, and a variety of tumors. Narnatumab (IMC-RON8; LY3012219) is a neutralizing monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP). This study assessed safety, maximum tolerated dose (MTD), pharmacokinetics, pharmacodynamics, and efficacy of narnatumab in patients with advanced solid tumors. Methods Narnatumab was administered intravenously weekly at 5, 10, 15, or 20 mg/kg or every 2 weeks at 15, 20, 30, or 40 mg/kg in 4-week cycles...
February 4, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/28160444/imaging-mass-cytometry
#20
EDITORIAL
Qing Chang, Olga I Ornatsky, Iram Siddiqui, Alexander Loboda, Vladimir I Baranov, David W Hedley
Imaging Mass Cytometry (IMC) is an expansion of mass cytometry, but rather than analyzing single cells in suspension, it uses laser ablation to generate plumes of particles that are carried to the mass cytometer by a stream of inert gas. Images reconstructed from tissue sections scanned by IMC have a resolution comparable to light microscopy, with the high content of mass cytometry enabled through the use of isotopically labeled probes and ICP-MS detection. Importantly, IMC can be performed on paraffin-embedded tissue sections, so can be applied to the retrospective analysis of patient cohorts whose outcome is known, and eventually to personalized medicine...
February 2017: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
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