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https://www.readbyqxmd.com/read/28730864/automatic-rbg-depth-pressure-anthropometric-analysis-and-individualised-sleep-solution-prescription
#1
Jordi Esquirol Caussa, Cristina Palmero Cantariño, Vanessa Bayo Tallón, Miquel Àngel Cos Morera, Sergio Escalera Domínguez, David Sánchez, Maider Sánchez Padilla, Noelia Serrano Domínguez, Mireia Relats Vilageliu
INTRODUCTION: Sleep surfaces must adapt to individual somatotypic features to maintain a comfortable, convenient and healthy sleep, preventing diseases and injuries. Individually determining the most adequate rest surface can often be a complex and subjective question. OBJECTIVES: To design and validate an automatic multimodal somatotype determination model to automatically recommend an individually designed mattress-topper-pillow combination. METHODS: Design and validation of an automated prescription model for an individualised sleep system is performed through a single-image 2 D-3 D analysis and body pressure distribution, to objectively determine optimal individual sleep surfaces combining five different mattress densities, three different toppers and three cervical pillows...
July 21, 2017: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/28728577/integrating-data-from-randomized-controlled-trials-and-observational-studies-to-predict-the-response-to-pregabalin-in-patients-with-painful-diabetic-peripheral-neuropathy
#2
Joe Alexander, Roger A Edwards, Alberto Savoldelli, Luigi Manca, Roberto Grugni, Birol Emir, Ed Whalen, Stephen Watt, Marina Brodsky, Bruce Parsons
BACKGROUND: More patient-specific medical care is expected as more is learned about variations in patient responses to medical treatments. Analytical tools enable insights by linking treatment responses from different types of studies, such as randomized controlled trials (RCTs) and observational studies. Given the importance of evidence from both types of studies, our goal was to integrate these types of data into a single predictive platform to help predict response to pregabalin in individual patients with painful diabetic peripheral neuropathy (pDPN)...
July 20, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28717201/cognitive-brain-responses-during-circadian-wake-promotion-evidence-for-sleep-pressure-dependent-hypothalamic-activations
#3
Carolin F Reichert, Micheline Maire, Virginie Gabel, Antoine U Viola, Thomas Götz, Klaus Scheffler, Markus Klarhöfer, Christian Berthomier, Werner Strobel, Christophe Phillips, Eric Salmon, Christian Cajochen, Christina Schmidt
The two-process model of sleep-wake regulation posits that sleep-wake-dependent homeostatic processes interact with the circadian timing system to affect human behavior. The circadian timing system is fundamental to maintaining stable cognitive performance, as it counteracts growing homeostatic sleep pressure during daytime. Using magnetic resonance imaging, we explored brain responses underlying working memory performance during the time of maximal circadian wake-promotion under varying sleep pressure conditions...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28714081/combining-two-model-systems-of-psychosis-the-effects-of-schizotypy-and-sleep-deprivation-on-oculomotor-control-and-psychotomimetic-states
#4
Inga Meyhöfer, Maria Steffens, Eliana Faiola, Anna-Maria Kasparbauer, Veena Kumari, Ulrich Ettinger
Model systems of psychosis, such as schizotypy or sleep deprivation, are valuable in informing our understanding of the etiology of the disorder and aiding the development of new treatments. Schizophrenia patients, high schizotypes, and sleep-deprived subjects are known to share deficits in oculomotor biomarkers. Here, we aimed to further validate the schizotypy and sleep deprivation models and investigated, for the first time, their interactive effects on smooth pursuit eye movements (SPEM), prosaccades, antisaccades, predictive saccades, and measures of psychotomimetic states, anxiety, depression, and stress...
July 17, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28713328/recovery-from-unrecognized-sleep-loss-accumulated-in-daily-life-improved-mood-regulation-via-prefrontal-suppression-of-amygdala-activity
#5
Yuki Motomura, Shingo Kitamura, Kyoko Nakazaki, Kentaro Oba, Ruri Katsunuma, Yuri Terasawa, Akiko Hida, Yoshiya Moriguchi, Kazuo Mishima
Many modern people suffer from sleep debt that has accumulated in everyday life but is not subjectively noticed [potential sleep debt (PSD)]. Our hypothesis for this study was that resolution of PSD through sleep extension optimizes mood regulation by altering the functional connectivity between the amygdala and prefrontal cortex. Fifteen healthy male participants underwent an experiment consisting of a baseline (BL) evaluation followed by two successive interventions, namely, a 9-day sleep extension followed by one night of total sleep deprivation (TSD)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28711192/predictors-of-anxiety-in-early-stage-parkinson-s-disease-results-from-the-first-two-years-of-a-prospective-cohort-study
#6
Sonja Rutten, Peter M van der Ven, Daniel Weintraub, Gregory M Pontone, Albert F G Leentjens, Henk W Berendse, Ysbrand D van der Werf, Odile A van den Heuvel
AIM: Anxiety has a negative impact on daily functioning and quality of life in patients with Parkinson's disease (PD). This study aims at assessing which sociodemographic and clinical characteristics predict the course of anxiety in early PD. METHODS: The participants of this two-year prospective cohort study were recently diagnosed PD patients not receiving psychiatric medications or dopamine replacement therapy at baseline. Assessments were performed annually after baseline...
July 5, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28701628/study-of-chronic-pain-and-its-associated-risk-factors-among-japanese-industry-workers-the-quality-of-working-life-influenced-by-chronic-pain-qwlic-study
#7
Keiko Yamada, Kenta Wakaizumi, Kyosuke Fukai, Hiroyasu Iso, Tomotaka Sobue, Masahiko Shibata, Ko Matsudaira
OBJECTIVES: This study was performed to identify the prevalence, influence, and risk factors associated with chronic pain among Japanese industry workers. METHODS: We investigated 2,544 participants working at a manufacturing company A, a manufacturing company B, and 16 branch shops of a retail chain company C. The participants responded to self-administered questionnaires related to pain. Furthermore, data obtained from the lifestyle interview sheet of an annual health screening examination and those obtained from the questionnaires were merged...
July 13, 2017: Sangyō Eiseigaku Zasshi, Journal of Occupational Health
https://www.readbyqxmd.com/read/28700701/development-and-validation-of-the-maugeri-sleep-quality-and-distress-inventory-masqudi-17
#8
Elisa Morrone, Cinzia Sguazzin, Giorgio Bertolotti, Andrea Giordano, Alberto Braghiroli, Gian Luigi Balestroni, Raffaele Manni, Luigi Ferini Strambi, Vincenza Castronovo, Marco Zucconi, Fabrizio De Carli, Eleonora Pinna, Marcella Ottonello, Ines Giorgi, Michele Terzaghi, Sara Marelli, Francesco Fanfulla
OBJECTIVES: The aim of this study was to develop and validate a questionnaire designed to measure the impact of sleep impairment on emotional distress in patients with various sleep disorders. METHODS: Five experts created an item data-bank pertaining to sleep-related psychological symptoms and somatic perceptions. Fifty patients in two focus groups examined each item for: a) word clarity (indicating any ambiguity of interpretation) and b) appropriateness for the target population...
2017: PloS One
https://www.readbyqxmd.com/read/28676955/a-novel-approach-for-acoustic-estimation-of-neck-fluid-volume-between-men-and-women
#9
Mehrnaz Shokrollahi, Frank Rudzicz, Daniel Vena, T Douglas Bradley, Azadeh Yadollahi
Obstructive Sleep apnea can be caused by fluid shift from the legs to the neck that narrows the upper airway (UA) and contributes to changes in tracheal sound. Tracheal sound is generated from the turbulent airflow in the pharynx and respiratory airways and it has recently been used to estimate increases in neck fluid volume (NFV). However, tracheal sound is also highly variable among people, especially across the sexes. In this paper, a novel method is proposed to select tracheal sound features towards estimating NFV in men and women separately...
July 5, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28676839/mechanisms-underlying-improvement-in-obstructive-sleep-apnea-syndrome-by-uvulopalatopharyngoplasty
#10
Takahisa Yamamoto, Naoko Fujii, Yoichi Nishimura, Noboru Iwata, Seiichi Nakata
In a previous case report, we determined for the first time that uvulopalatopharyngoplasty (UPPP) does not change the volume of the upper airway but causes morphological changes in the entire upper airway. The objective of this study is to elucidate the mechanisms underlying the improvement in obstructive sleep apnea syndrome (OSAS) by UPPP. We present an additional case involving a patient with OSAS treated using UPPP. Morphological and numerical parameter changes after surgery were compared with the corresponding preoperative values...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28675633/increased-urine-production-due-to-leg-fluid-displacement-reduces-hours-of-undisturbed-sleep
#11
Keisuke Kiba, Akihide Hirayama, Motokiyo Yoshikawa, Yutaka Yamamoto, Kazumasa Torimoto, Nobutaka Shimizu, Nobumichi Tanaka, Kiyohide Fujimoto, Hirotsugu Uemura
OBJECTIVE: To investigate whether or not the leg fluid displacement observed when moving from the standing to recumbent position at bedtime reduces the hours of undisturbed sleep (HUS). METHODS: Men aged 50 years or older who were hospitalized for urological diseases were investigated. Body water evaluation was performed three times with a bioelectric impedance method: (i) 17:00, (ii) 30 min after (short-term), and (iii) waking up (long-term). A frequency volume chart was used to evaluate the status of nocturnal urine production, and the factors affecting HUS were investigated...
July 3, 2017: Lower Urinary Tract Symptoms
https://www.readbyqxmd.com/read/28675095/development-and-pilot-testing-of-an-objective-structured-clinical-examination-for-obstructive-sleep-apnea
#12
Nasir I Bhatti, Muhammad Abbas Abid, C Matthew Stewart, Carol Fleishman, Niall Jefferson, Stacey L Ishman
Objective Our aim was (1) to develop an objective structured clinical examination (OSCE) for obstructive sleep apnea (OSA) and (2) to test the reliability and evaluate the feasibility of this OSCE while assessing residents' clinical skills in multiple core competencies via the standardized patient methodology. Study Design Development of assessment tool. Setting Johns Hopkins Medicine Simulation Center. Subjects and Methods Residents of the Department of Otolaryngology-Head and Neck Surgery at The Johns Hopkins University School of Medicine were invited to participate...
June 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28674128/predictors-for-future-activity-limitation-in-women-with-chronic-low-back-pain-consulting-primary-care-a-2-year-prospective-longitudinal-cohort-study
#13
Lena Nordeman, Lena Thorselius, Ronny Gunnarsson, Kaisa Mannerkorpi
OBJECTIVES: To assess if body function, activity, participation, health-related quality of life and lifestyle behavioural factors can predict activity limitation in women with chronic low back pain (CLBP) in primary healthcare (PHC) 2 years later. DESIGN: A 2-year prospective longitudinal cohort study within PHC. SETTINGS: PHC in southwestern Sweden. PARTICIPANTS: The cohort comprised 130 women with CLBP attending PHC at baseline 2004-2005 and were reassessed after 2 years...
July 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28668621/circadian-disruption-affects-initial-learning-but-not-cognitive-flexibility-in-an-automated-set-shifting-task-in-adult-long-evans-rats
#14
Audrey L Robertson, Rekha C Balachandran, Megan M Mahoney, Paul A Eubig
A sizeable percent of adults are subject to circadian disturbances such as shift work, which involves misalignment of time of light exposure, activity periods, sleep, and eating. Chronic adherence to disruptive circadian schedules can negatively impact cognitive functioning. Developing preclinical models of circadian disruption allow investigation of the relationship and underlying mechanisms between circadian disruption and cognitive functioning. We placed adult Long-Evans rats of both sexes on a 12:12h light:dark schedule in which rats performed an automated operant-behavior task for 3months, with daily testing occurring either 4h after lights-on or lights-off...
June 29, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28667510/a-randomized-controlled-trial-of-ganaxolone-in-posttraumatic-stress-disorder
#15
Ann M Rasmusson, Christine E Marx, Sonia Jain, Gail M Farfel, Julia Tsai, Xiaoying Sun, Thomas D Geracioti, Mark B Hamner, James Lohr, Richard Rosse, Lanier Summerall, Jennifer C Naylor, Cristine Cusin, Ariel J Lang, Rema Raman, Murray B Stein
Preclinical and clinical research supports a role for neuroactive steroids in the pathophysiology of posttraumatic stress disorder (PTSD). We investigated ganaxolone (a synthetic 3β-methylated derivative of allopregnanolone, a GABAergic neuroactive steroid) for treatment of PTSD in a proof-of-concept, multisite, double-blind, placebo-controlled trial. Veteran and non-veteran participants (n = 112) were randomized to ganaxolone or placebo at biweekly escalating doses of 200, 400, and 600 mg twice daily for 6 weeks...
August 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28661071/scheduled-meal-accelerates-entrainment-to-a-6-hours-phase-advance-by-shifting-central-and-peripheral-oscillations-in-rats
#16
L M Ubaldo-Reyes, R M Buijs, C Escobar, M Ángeles-Castellanos
Traveling across several time zones requires a fast adjustment of the circadian system and the differential adjustment speeds of organs and systems results in what is commonly referred as jet lag. During this transitory state of circadian disruption, individuals feel discomfort, appetite loss, fatigue, disturbed sleep and deficient performance of multiple tasks. We have demonstrated that after a 6-h phase advance of the light-dark cycle (LD) scheduled food in phase with the new night onset can speed up re-entrainment...
June 29, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28658883/artificial-neural-network-ann-model-to-predict-depression-among-geriatric-population-at-a-slum-in-kolkata-india
#17
Arkaprabha Sau, Ishita Bhakta
INTRODUCTION: Depression is one of the most important causes of mortality and morbidity among the geriatric population. Although, the aging brain is more vulnerable to depression, it cannot be considered as physiological and an inevitable part of ageing. Various sociodemographic and morbidity factors are responsible for the depression among them. Using Artificial Neural Network (ANN) model depression can be predicted from various sociodemographic variables and co morbid conditions even at community level by the grass root level health care workers...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28658343/overweight-in-youth-and-sleep-quality-is-there-a-link
#18
Susana Rebelo Pacheco, Ana Margalha Miranda, Raquel Coelho, Ana Cristina Monteiro, Graciete Bragança, Helena Cristina Loureiro
Objective: Overweight seems to be related to a higher prevalence of sleep disturbances. Decreased sleep duration and altered sleep quality are risk factors for obesity. Our aim was to compare the sleep pattern of overweight children with that of a matched control group and assess the relationship between sleep quality and obesity. Materials and methods: Retrospective cohort study comparing 41 overweight children with a normal-weight control group, both submitted to polysomnography...
June 26, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28656362/limited-capacity-of-working-memory-in-unihemispheric-random-walks-implies-conceivable-slow-dispersal
#19
Kun Wei, Suchuan Zhong
Phenomenologically inspired by dolphins' unihemispheric sleep, we introduce a minimal model for random walks with physiological memory. The physiological memory consists of long-term memory which includes unconscious implicit memory and conscious explicit memory, and working memory which serves as a multi-component system for integrating, manipulating and managing short-term storage. The model assumes that the sleeping state allows retrievals of episodic objects merely from the episodic buffer where these memory objects are invoked corresponding to the ambient objects and are thus object-oriented, together with intermittent but increasing use of implicit memory in which decisions are unconsciously picked up from historical time series...
June 27, 2017: Biological Cybernetics
https://www.readbyqxmd.com/read/28652746/association-between-serotonin-transporter-polymorphisms-5-httlpr-and-the-madrs-dysphoria-retardation-and-vegetative-subscale-scores-in-the-treatment-of-depression
#20
Hitoshi Takahashi, Hisashi Higuchi, Kazuhiro Sato, Mitsuhiro Kamata, Keizo Yoshida, Katsuji Nishimura
OBJECTIVE: We investigated the association between serotonin- or 5-hydroxytryptamine (5-HT)-related gene polymorphisms and response to antidepressant treatment in a specific symptom cluster of major depression by using the three-factor model of the Montgomery-Åsberg Depression Rating Scale (MADRS), ie, dysphoria (items of sadness, pessimistic thoughts, and suicidal thoughts), retardation (items of lassitude, inability to feel, apparent sadness, and concentration difficulties), and vegetative symptoms (items of reduced sleep, reduced appetite, and inner tension)...
2017: Neuropsychiatric Disease and Treatment
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