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https://www.readbyqxmd.com/read/28801919/familial-associations-of-female-breast-cancer-with-other-cancers
#1
Guoqiao Zheng, Hongyao Yu, Akseli Hemminki, Asta Försti, Kristina Sundquist, Kari Hemminki
Familial risks of breast cancer (BC) are well established but whether BC clusters with other, i.e. discordant, cancers is less certain but of interest for the identification of common genetic and possible environmental factors contributing to a general cancer susceptibility. We apply a novel approach to search for familial associations of BC with other (discordant) cancers based on the Swedish Family-Cancer Database. Relative risks (RRs) were calculated for BC in families with increasing numbers of patients with discordant cancer X, and conversely, familial RRs for cancer X in families with increasing numbers of BC patients...
August 12, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28801224/celiac-disease-and-increased-risk-of-pneumococcal-infection-a-systematic-review-and-meta-analysis
#2
Malorie Simons, Lori A J Scott-Sheldon, Yesenia Risech-Neyman, Steven Moss, Jonas F Ludvigsson, Peter Hr Green
BACKGROUND: Celiac disease has been associated with hyposplenism and multiple case reports link Celiac disease and pneumococcal infections; however, increased risk of pneumococcal infection in celiac disease has not been confirmed. The purpose of this study was to conduct a systematic review to determine the risk of pneumococcal infections in celiac disease. METHODS: Relevant studies were identified using electronic bibliographic searches of PubMed, OVID Medline and EMBASE (1980 to February 2017) and reviewing abstracts from major conferences in gastroenterology...
August 8, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28799214/refill-adherence-and-persistence-to-lipid-lowering-medicines-in-patients-with-type-2-diabetes-a-nation-wide-register-based-study
#3
Sofia Axia Karlsson, Christel Hero, Björn Eliasson, Stefan Franzén, Ann-Marie Svensson, Mervete Miftaraj, Soffia Gudbjörnsdottir, Katarina Eeg-Olofsson, Karolina Andersson Sundell
PURPOSE: This study aimed to describe and compare refill adherence and persistence to lipid-lowering medicines in patients with type 2 diabetes by previous cardiovascular disease (CVD). METHODS: We followed 97 595 patients (58% men; 23% with previous CVD) who were 18 years of age or older when initiating lipid-lowering medicines in 2007-2010 until first fill of multi-dose dispensed medicines, death, or 3 years. Using personal identity numbers, we linked individuals' data from the Swedish Prescribed Drug Register, the Swedish National Diabetes Register, the National Patient Register, the Cause of Death Register, and the Longitudinal Integration Database for Health Insurance and Labour Market Studies...
August 11, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28797662/amputation-rates-mortality-and-pre-operative-comorbidities-in-patients-revascularised-for-intermittent-claudication-or-critical-limb-ischaemia-a-population-based-study
#4
E Baubeta Fridh, M Andersson, M Thuresson, B Sigvant, B Kragsterman, S Johansson, P Hasvold, M Falkenberg, J Nordanstig
OBJECTIVES: The aims of this population based study were to describe mid- to long-term amputation risk, cumulative incidence of death or amputation, and differences in pre-operative comorbidities in patients revascularised for lower limb peripheral artery disease (PAD). METHODS: This was an observational cohort study. Data from the Swedish National Quality Registry for Vascular Surgery (Swedvasc) were combined with mandatory national health care registries and patient medical records...
August 7, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28782979/the-junior-temperament-and-character-inventory-jtci-psychometric-properties-of-multi-informant-ratings
#5
Karin Boson, Sven Brändström, Sören Sigvardsson
The aims of the study were (a) to establish norms for the Swedish child self-report and caregiver rating versions of the Junior and Temperament Character Inventory (JTCI) among young adolescents, (b) to investigate its psychometric properties, and (c) to investigate congruence between children's self-reports and caregivers' ratings of a child's personality. The sample was a general population of 1,046 children ages 12-14 years and 654 caregivers. The JTCI was found to be reliable on all dimensions except Persistence in the child self-report version...
August 7, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28761652/incidence-of-severe-hypoglycemia-in-children-with-type-1-diabetes-in-the-nordic-countries-in-the-period-2008-2012-association-with-hemoglobin-a-1c-and-treatment-modality
#6
N H Birkebaek, A K Drivvoll, K Aakeson, R Bjarnason, A Johansen, U Samuelsson, T Skrivarhaug, A V Thorsson, J Svensson
OBJECTIVE: Treatment of type 1 diabetes has been intensified aiming at normalizing blood glucose, which may increase the risk of severe hypoglycemia (SH). We aimed to compare the incidence of SH events in the four Nordic countries Denmark, Iceland, Norway and Sweden, and to assess the influence of hemoglobin A1c (HbA1c) and treatment modalities on the frequency of SH; particularly, to explore if a HbA1c target ≤6.7% (50 mmol/mol) is feasible. RESEARCH DESIGN AND METHODS: Data on children below 15 years with a diabetes duration more than 1 year, registered in the national childhood diabetes databases in the four Nordic countries from 2008 to 2012, were compiled...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28753671/self-reported-infections-during-international-travel-and-notifiable-infections-among-returning-international-travellers-sweden-2009-2013
#7
Viktor Dahl, Anders Wallensten
We studied food and water-borne diseases (FWDs), sexually transmitted diseases (STDs), vector-borne diseases (VBDs) and diseases vaccinated against in the Swedish childhood vaccination programme among Swedish international travellers, in order to identify countries associated with a high number of infections. We used the national database for notifiable infections to estimate the number of FWDs (campylobacteriosis, salmonellosis, giardiasis, shigellosis, EHEC, Entamoeba histolytica, yersinosis, hepatitis A, paratyphoid fever, typhoid fever, hepatitis E, listeriosis, cholera), STIs (chlamydia, gonorrhoea and acute hepatitis B), VBDs (dengue fever, malaria, West Nile fever, Japanese encephalitis and yellow fever) and diseases vaccinated against in the Swedish childhood vaccination programme (pertussis, measles, mumps, rubella, diphtheria) acquired abroad 2009-2013...
2017: PloS One
https://www.readbyqxmd.com/read/28738835/incidence-of-and-risk-factors-for-nephrolithiasis-in-patients-with-gout-and-the-general-population-a-cohort-study
#8
A J Landgren, L T H Jacobsson, U Lindström, T Z S Sandström, P Drivelegka, L Björkman, E Fjellstedt, M Dehlin
BACKGROUND: Nephrolithiasis (NL) is known to be associated with gout, although there are few comparative studies on risk and risk factors for NL in gout compared to population cohorts. In this cohort study we investigated: (1) overall incidence of NL in gout (cases) and general population controls; (2) risk and risk factors (common comorbidities and medications) for first-time NL in cases and controls separately. METHODS: Cases (n = 29,968) and age-matched and sex-matched controls (n = 138,678) were identified from the regional healthcare database in western Sweden (VEGA)...
July 24, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28736487/development-blocks-in-innovation-networks-the-swedish-manufacturing-industry-1970-2007
#9
Josef Taalbi
The notion of development blocks (Dahmén, 1950, 1991) suggests the co-evolution of technologies and industries through complementarities and the overcoming of imbalances. This study proposes and applies a methodology to analyse development blocks empirically. To assess the extent and character of innovational interdependencies between industries the study combines analysis of innovation biographies and statistical network analysis. This is made possible by using data from a newly constructed innovation output database for Sweden...
2017: Journal of Evolutionary Economics
https://www.readbyqxmd.com/read/28705243/trends-in-treatment-with-antipsychotic-medication-in-relation-to-national-directives-in-people-with-dementia-a-review-of-the-swedish-context
#10
Staffan Karlsson, Ingalill Rahm Hallberg, Patrik Midlöv, Cecilia Fagerström
BACKGROUND: The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care in nursing homes as reported in the most recent empirical studies on the topic, and to relate these trends to directives from the national authorities. METHODS: The study included two scoping review studies based on searches of electronic databases as well as the Swedish directives in the field. RESULTS: During the past decade, directives have been developed for antipsychotic medication in Sweden...
July 14, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28701784/familial-associations-of-colorectal-cancer-with-other-cancers
#11
Hongyao Yu, Akseli Hemminki, Kristina Sundquist, Kari Hemminki
Colorectal cancer (CRC) has a strong familial component which extends to discordant cancers (ie non-CRC tumors). This is best seen in cancer syndromes such as hereditary non-polyposis colorectal cancer (HNPCC) which predisposes to several tumor types. Population-based family studies have also found discordant associations for CRC but they have included cancers which manifest in HNPCC, and there is no convincing evidence of discordant associations beyond the known syndromes. We address familial associations of non-CRC tumors with CRC using the resources of the Swedish Family-Cancer Database and applying a powerful approach of assessing familial relative risks in families of increasing numbers of patients with discordant cancers...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28697254/association-between-alendronate-use-and-hip-fracture-risk-in-older-patients-using-oral-prednisolone
#12
Kristian F Axelsson, Anna G Nilsson, Hans Wedel, Dan Lundh, Mattias Lorentzon
Importance: Oral glucocorticoid treatment increases fracture risk, and evidence is lacking regarding the efficacy of alendronate to protect against hip fracture in older patients using glucocorticoids. Objective: To investigate whether alendronate treatment in older patients using oral prednisolone is associated with decreased hip fracture risk and adverse effects. Design, Setting, and Participants: Retrospective cohort study using a national database (N = 433 195) of patients aged 65 years or older undergoing a health evaluation (baseline) at Swedish health care facilities; 1802 patients who were prescribed alendronate after at least 3 months of oral prednisolone treatment (≥5 mg/d) were identified...
July 11, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28685921/prediction-of-outcome-after-curative-surgery-for-colorectal-cancer-preoperative-haemoglobin-crp-and-albumin
#13
Monika Egenvall, Malin Mörner, Anna Martling, Ulf Gunnarsson
AIM: The aim was to evaluate a scoring system using the values of preoperative haemoglobin, C-reactive protein (CRP) and serum albumin to predict colorectal cancer recurrence and survival. METHOD: Data on all curative resections for Stages I-III colorectal cancer performed at a tertiary referral hospital 2007-2010 have been recorded ion the Swedish Colorectal Cancer Registry and were matched to the local databases for laboratory results and blood transfusion. Patients who died within 30 days or during primary hospital admission were excluded...
July 7, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28675583/experiencing-health-related-quality-of-life-in-paediatric-short-stature-a-cross-cultural-analysis-of-statements-from-patients-and-parents
#14
Rachel Sommer, Monika Bullinger, John Chaplin, Ju-Ky Do, Mick Power, Andreas Pleil, Julia Quitmann
OBJECTIVES: Direct assessment of the patient perspective is necessary to thoroughly understand patients' experiences of disease. We aimed to examine information from children with short stature on their perceived HrQoL within 5 European countries. METHODS: Patients, identified through clinical databases, were approached by their clinicians according to the inclusion criteria regarding a diagnosis of growth hormone deficiency or idiopathic short stature and age requirements...
July 4, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28674694/visualization-of-global-disease-burden-for-the-optimization-of-patient-management-and-treatment
#15
Winfried Schlee, Deborah A Hall, Niklas K Edvall, Berthold Langguth, Barbara Canlon, Christopher R Cederroth
BACKGROUND: The assessment and treatment of complex disorders is challenged by the multiple domains and instruments used to evaluate clinical outcome. With the large number of assessment tools typically used in complex disorders comes the challenge of obtaining an integrative view of disease status to further evaluate treatment outcome both at the individual level and at the group level. Radar plots appear as an attractive visual tool to display multivariate data on a two-dimensional graphical illustration...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28670582/other-cancers-in-lung-cancer-families-are-overwhelmingly-smoking-related-cancers
#16
Hongyao Yu, Christoph Frank, Akseli Hemminki, Kristina Sundquist, Kari Hemminki
Familial risks of lung cancer are well-established, but whether lung cancer clusters with other discordant cancers is less certain, particularly beyond smoking-related sites, which may provide evidence on genetic contributions to lung cancer aetiology. We used a novel approach to search for familial associations in the Swedish Family-Cancer Database. This involved assessment of familial relative risk for cancer X in families with increasing numbers of lung cancer patients and, conversely, relative risks for lung cancer in families with increasing numbers of patients with cancers X...
April 2017: ERJ Open Research
https://www.readbyqxmd.com/read/28664570/swedish-population-based-study-of-pupils-showed-that-foster-children-faced-increased-risks-for-ill-health-negative-lifestyles-and-school-failure
#17
Lisbet Engh, Staffan Janson, Birgitta Svensson, Carl-Gustaf Bornehag, Ulla-Britt Eriksson
AIM: This population-based study explored if foster children faced a higher risk of health problems than children of the same age who were not in foster care. METHODS: Data for 13,739 pupils aged 10, 13 and 16 years were obtained from the Pupil Health Database in the county of Värmland, Sweden, for the school years 2012/2013 and 2013/2014. These included data on school performance, health, lifestyle and social relationships, based on children's interviews with school nurses...
June 30, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28660652/change-in-use-of-sleep-medications-after-gastric-bypass-surgery-or-intensive-lifestyle-treatment-in-adults-with-obesity
#18
Winda L Ng, Anna Peeters, Ingmar Näslund, Johan Ottosson, Kari Johansson, Claude Marcus, Jonathan E Shaw, Gustaf Bruze, Johan Sundström, Martin Neovius
OBJECTIVE: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity. METHODS: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were identified through the Scandinavian Obesity Surgery Registry and a Swedish commercial weight loss database. The two cohorts were matched on BMI, age, sex, education, history of hypnotics and/or sedatives use, and treatment year (surgery n = 20,626; lifestyle n = 11,973; 77% women, mean age 41 years, mean BMI 41 kg/m(2) )...
August 2017: Obesity
https://www.readbyqxmd.com/read/28659510/swedish-massage-a-systematic-review-of-its-physical-and-psychological-benefits
#19
Débora M Barreto, Marcus V A Batista
Context • Swedish massage is the systematic application of manual pressure and the movement of soft tissue, with rhythmical pressure and stroking to obtain or maintain health. Studies have revealed its many benefits. Objective • The aim of the current study was to determine the results of past studies that evaluated the benefits of Swedish massage for various populations and to highlight its relevance as an alternative medical practice in health promotion and disease prevention. Methods • The research team performed a review of the literature using the key terms massage, relaxation, and benefits of massage...
April 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/28657970/trends-in-otitis-media-incidence-after-conjugate-pneumococcal-vaccination-a-national-observational-study
#20
Marie Gisselsson-Solen
BACKGROUND: Pneumococcal conjugate vaccine (PCV) was introduced in 2000. The first 7-valent vaccine was followed by a 13-valent vaccine (PCV13) with the same conjugate, and a 10-valent vaccine (PCV10), conjugated to protein D from H. influenzae. The vaccines offer some protection against pneumococcal acute otitis media (AOM), and, with PCV10, possibly also some protection against H. influenzae AOM. PCV7 was introduced in Sweden in 2009, but from 2010, Swedish counties were free to use either PCV13 or PCV10...
June 27, 2017: Pediatric Infectious Disease Journal
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