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https://www.readbyqxmd.com/read/28888265/temporal-changes-in-myocardial-infarction-incidence-rates-are-associated-with-periods-of-perceived-psychosocial-stress-a-swedeheart-national-registry-study
#1
John Wallert, Claes Held, Guy Madison, Erik Mg Olsson
BACKGROUND: Psychosocial stress might trigger myocardial infarction (MI). Increased MI incidence coincides with recurrent time periods during the year perceived as particularly stressful in the population. METHODS: A stress-triggering hypothesis on the risk of MI onset was investigated with Swedish population data on MI hospital admission date and symptom onset date (N=156,690; 148,176) as registered from 2006 through 2013 in the national quality registry database Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART)...
September 2017: American Heart Journal
https://www.readbyqxmd.com/read/28882281/the-state-of-the-residential-fire-fatality-problem-in-sweden-epidemiology-risk-factors-and-event-typologies
#2
Anders Jonsson, Carl Bonander, Finn Nilson, Fredrik Huss
INTRODUCTION: Residential fires represent the largest category of fatal fires in Sweden. The purpose of this study was to describe the epidemiology of fatal residential fires in Sweden and to identify clusters of events. METHOD: Data was collected from a database that combines information on fatal fires with data from forensic examinations and the Swedish Cause of Death-register. Mortality rates were calculated for different strata using population statistics and rescue service turnout reports...
September 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28879052/obesity-is-a-strong-predictor-of-worse-clinical-outcomes-and-treatment-responses-in-early-rheumatoid-arthritis-results-from-the-swefot-trial
#3
Adrian Levitsky, Kerstin Brismar, Ingiäld Hafström, Karen Hambardzumyan, Cecilia Lourdudoss, Ronald F van Vollenhoven, Saedis Saevarsdottir
OBJECTIVES: The aim of this paper was to analyse the impact of obesity, in addition to known predictors, on disease outcome in early rheumatoid arthritis (RA). METHODS: Body mass index (BMI) was available in 260 patients from the Swedish pharmacotherapy trial (SWEFOT). Differences in disease activity (DAS28), functional impairment (HAQ), pain (Visual Analogue Scale, VAS-pain) and radiographic damage were evaluated over 24 months between BMI categories (obese BMI >30, n=43; overweight BMI=25-29...
2017: RMD Open
https://www.readbyqxmd.com/read/28874396/body-height-and-incident-risk-of-venous-thromboembolism-a-cosibling-design
#4
Bengt Zöller, Jianguang Ji, Jan Sundquist, Kristina Sundquist
BACKGROUND: Body height has been associated with an increased risk of venous thromboembolism (VTE), but the association can be confounded with shared familial factors (genetic/environmental). A cosibling design is useful for deeper understanding about the relationship between VTE and height. METHODS AND RESULTS: From Swedish national registry databases, we used a corelative design with full siblings alongside a general Swedish population sample. A cohort of male conscripts (n=1 610 870), born in 1951 to 1992 without previous VTE, was followed from enlistment (1969-2010) until 2012...
October 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/28873959/sudden-cardiac-death-among-the-young-in-sweden-from-2000-to-2010-an-autopsy-based-study
#5
Aase Wisten, Peter Krantz, Eva-Lena Stattin
Aims: To study the incidence and aetiology of sudden cardiac death (SCD) in 1- to 35-year-olds in Sweden from 2000 to 2010. Methods and results: We used the database of the Swedish National Board of Forensic Medicine and the Swedish Cause of Death Registry and identified SCD cases by review of forensic files and death certificates. We identified 552 individuals with SCD in 1- to 35-year-olds; 156 (28%) were women. In 393 (71%), a forensic autopsy had been performed; in 131 (24%), a clinical autopsy had been performed; in 28 (5%) with no autopsy, a cardiac disease was diagnosed before death...
August 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28857352/hip-fracture-risk-and-safety-with-alendronate-treatment-in-the-oldest-old
#6
K F Axelsson, M Wallander, H Johansson, D Lundh, M Lorentzon
BACKGROUND: There is high evidence for secondary prevention of fractures, including hip fracture, with alendronate treatment, but alendronate's efficacy to prevent hip fractures in the oldest-old (≥80 years old), the population with the highest fracture risk, has not been studied. OBJECTIVE: To investigate if alendronate treatment among the oldest old with prior fracture was related to decreased hip fracture rate and sustained safety. METHODS: Using a national database of men and women undergoing a fall risk assessment at a Swedish healthcare facility, we identified 90 795 patients who were 80 years or older and had a prior fracture...
August 30, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28845900/trends-in-hip-replacements-between-1999-and-2012-in-sweden
#7
Peter Cnudde, Szilard Nemes, Erik Bülow, John Timperley, H Malchau, Johan Kärrholm, Göran Garellick, Ola Rolfson
National Registers document changes in the circumstance, practice and outcome of surgery with the passage of time. In the context of total hip replacement (THR), registers can help elucidate the relevant factors that affect the clinical outcome. We evaluated the evolution of factors related to patient, surgical procedure, socio-economy and various outcome parameters after merging databases of the Swedish Hip Arthroplasty Register, Statistics Sweden and the National Board of Health and Welfare. Data on 193,253 THRs (164,113 patients) operated between 1999 and 2012 were merged...
August 28, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28836973/comparison-and-analysis-of-reoperations-in-two-different-treatment-protocols-for-trochanteric-hip-fractures-postoperative-technical-complications-with-dynamic-hip-screw-intramedullary-nail-and-medoff-sliding-plate
#8
Johnny Paulsson, Josefine Corin Stig, Ola Olsson
BACKGROUND: In treatment of unstable trochanteric fractures dynamic hip screw and Medoff sliding plate devices are designed to allow secondary fracture impaction, whereas intramedullary nails aim to maintain fracture alignment. Different treatment protocols are used by two similar Swedish regional emergency care hospitals. Dynamic hip screw is used for fractures considered as stable within the respective treatment protocol, whereas one treatment protocol (Medoff sliding plate/dynamic hip screw) uses biaxial Medoff sliding plate for unstable pertrochanteric fractures and uniaxial Medoff sliding plate for subtrochanteric fractures, the second (intramedullary nail/dynamic hip screw) uses intramedullary nail for subtrochanteric fractures and for pertrochanteric fractures with intertrochanteric comminution or subtrochanteric extension...
August 24, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28836035/familial-associations-of-male-breast-cancer-with-other-cancers
#9
Guoqiao Zheng, Hongyao Yu, Akseli Hemminki, Asta Försti, Kristina Sundquist, Kari Hemminki
PURPOSE: Male breast cancer is associated with female breast cancer in families but whether male breast cancer clusters with other discordant cancers has not been studied. As concordant male breast cancers are utterly rare, discordant associations of male breast cancer with other cancers may reveal genetic and possible environmental risk factors contributing to male breast cancer susceptibility. METHODS: We calculated relative risks (RRs) for male breast cancer in families with discordant cancers, and conversely, for discordant cancers in families of male breast cancer patients, based on 15...
August 23, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28832569/swegen-a-whole-genome-data-resource-of-genetic-variability-in-a-cross-section-of-the-swedish-population
#10
Adam Ameur, Johan Dahlberg, Pall Olason, Francesco Vezzi, Robert Karlsson, Marcel Martin, Johan Viklund, Andreas Kusalananda Kähäri, Pär Lundin, Huiwen Che, Jessada Thutkawkorapin, Jesper Eisfeldt, Samuel Lampa, Mats Dahlberg, Jonas Hagberg, Niclas Jareborg, Ulrika Liljedahl, Inger Jonasson, Åsa Johansson, Lars Feuk, Joakim Lundeberg, Ann-Christine Syvänen, Sverker Lundin, Daniel Nilsson, Björn Nystedt, Patrik Ke Magnusson, Ulf Gyllensten
Here we describe the SweGen data set, a comprehensive map of genetic variation in the Swedish population. These data represent a basic resource for clinical genetics laboratories as well as for sequencing-based association studies by providing information on genetic variant frequencies in a cohort that is well matched to national patient cohorts. To select samples for this study, we first examined the genetic structure of the Swedish population using high-density SNP-array data from a nation-wide cohort of over 10 000 Swedish-born individuals included in the Swedish Twin Registry...
August 23, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28816174/-adverse-drug-reaction-reports-in-iceland-from-2013-to-2016-a-comparison-with-other-nordic-countries
#11
Sara Skulina Jonsdottir, Sigridur Maria Olafsdottir, Hrefna Gudmundsdottir
INTRODUCTION: Information regarding adverse drug reactions (ADRs) of new medications is based on clinical studies of selected populations. The reporting of ADRs from real-life use following the marketing of new active substances is instrumental for the continuous evaluation of their benefit-risk balance. The aim of this study was to determine the number and nature of ADR reports in Iceland and compare with other Nordic countries. MATERIALS AND METHODS: Reports of ADRs from 2013 to 2016 were examined using the Icelandic Medicines Agency´s database...
July 2017: Læknablađiđ
https://www.readbyqxmd.com/read/28801919/familial-associations-of-female-breast-cancer-with-other-cancers
#12
Guoqiao Zheng, Hongyao Yu, Akseli Hemminki, Asta Försti, Kristina Sundquist, Kari Hemminki
Familial risks of breast cancer (BC) are well established but whether BC clusters with other, i.e. discordant, cancers is less certain but of interest for the identification of common genetic and possible environmental factors contributing to a general cancer susceptibility. We apply a novel approach to search for familial associations of BC with other (discordant) cancers based on the Swedish Family-Cancer Database. Relative risks (RRs) were calculated for BC in families with increasing numbers of patients with discordant cancer X, and conversely, familial RRs for cancer X in families with increasing numbers of BC patients...
August 12, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28801224/celiac-disease-and-increased-risk-of-pneumococcal-infection-a-systematic-review-and-meta-analysis
#13
Malorie Simons, Lori A J Scott-Sheldon, Yesenia Risech-Neyman, Steven Moss, Jonas F Ludvigsson, Peter Hr Green
BACKGROUND: Celiac disease has been associated with hyposplenism and multiple case reports link Celiac disease and pneumococcal infections; however, increased risk of pneumococcal infection in celiac disease has not been confirmed. The purpose of this study was to conduct a systematic review to determine the risk of pneumococcal infections in celiac disease. METHODS: Relevant studies were identified using electronic bibliographic searches of PubMed, OVID Medline and EMBASE (1980 to February 2017) and reviewing abstracts from major conferences in gastroenterology...
August 8, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28799214/refill-adherence-and-persistence-to-lipid-lowering-medicines-in-patients-with-type-2-diabetes-a-nation-wide-register-based-study
#14
Sofia Axia Karlsson, Christel Hero, Björn Eliasson, Stefan Franzén, Ann-Marie Svensson, Mervete Miftaraj, Soffia Gudbjörnsdottir, Katarina Eeg-Olofsson, Karolina Andersson Sundell
PURPOSE: This study aimed to describe and compare refill adherence and persistence to lipid-lowering medicines in patients with type 2 diabetes by previous cardiovascular disease (CVD). METHODS: We followed 97 595 patients (58% men; 23% with previous CVD) who were 18 years of age or older when initiating lipid-lowering medicines in 2007-2010 until first fill of multi-dose dispensed medicines, death, or 3 years. Using personal identity numbers, we linked individuals' data from the Swedish Prescribed Drug Register, the Swedish National Diabetes Register, the National Patient Register, the Cause of Death Register, and the Longitudinal Integration Database for Health Insurance and Labour Market Studies...
August 11, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28797662/amputation-rates-mortality-and-pre-operative-comorbidities-in-patients-revascularised-for-intermittent-claudication-or-critical-limb-ischaemia-a-population-based-study
#15
E Baubeta Fridh, M Andersson, M Thuresson, B Sigvant, B Kragsterman, S Johansson, P Hasvold, M Falkenberg, J Nordanstig
OBJECTIVES: The aims of this population based study were to describe mid- to long-term amputation risk, cumulative incidence of death or amputation, and differences in pre-operative comorbidities in patients revascularised for lower limb peripheral artery disease (PAD). METHODS: This was an observational cohort study. Data from the Swedish National Quality Registry for Vascular Surgery (Swedvasc) were combined with mandatory national health care registries and patient medical records...
August 7, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28782979/the-junior-temperament-and-character-inventory-jtci-psychometric-properties-of-multi-informant-ratings
#16
Karin Boson, Sven Brändström, Sören Sigvardsson
The aims of the study were (a) to establish norms for the Swedish child self-report and caregiver rating versions of the Junior and Temperament Character Inventory (JTCI) among young adolescents, (b) to investigate its psychometric properties, and (c) to investigate congruence between children's self-reports and caregivers' ratings of a child's personality. The sample was a general population of 1,046 children ages 12-14 years and 654 caregivers. The JTCI was found to be reliable on all dimensions except Persistence in the child self-report version...
August 7, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28761652/incidence-of-severe-hypoglycemia-in-children-with-type-1-diabetes-in-the-nordic-countries-in-the-period-2008-2012-association-with-hemoglobin-a-1c-and-treatment-modality
#17
N H Birkebaek, A K Drivvoll, K Aakeson, R Bjarnason, A Johansen, U Samuelsson, T Skrivarhaug, A V Thorsson, J Svensson
OBJECTIVE: Treatment of type 1 diabetes has been intensified aiming at normalizing blood glucose, which may increase the risk of severe hypoglycemia (SH). We aimed to compare the incidence of SH events in the four Nordic countries Denmark, Iceland, Norway and Sweden, and to assess the influence of hemoglobin A1c (HbA1c) and treatment modalities on the frequency of SH; particularly, to explore if a HbA1c target ≤6.7% (50 mmol/mol) is feasible. RESEARCH DESIGN AND METHODS: Data on children below 15 years with a diabetes duration more than 1 year, registered in the national childhood diabetes databases in the four Nordic countries from 2008 to 2012, were compiled...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28753671/self-reported-infections-during-international-travel-and-notifiable-infections-among-returning-international-travellers-sweden-2009-2013
#18
Viktor Dahl, Anders Wallensten
We studied food and water-borne diseases (FWDs), sexually transmitted diseases (STDs), vector-borne diseases (VBDs) and diseases vaccinated against in the Swedish childhood vaccination programme among Swedish international travellers, in order to identify countries associated with a high number of infections. We used the national database for notifiable infections to estimate the number of FWDs (campylobacteriosis, salmonellosis, giardiasis, shigellosis, EHEC, Entamoeba histolytica, yersinosis, hepatitis A, paratyphoid fever, typhoid fever, hepatitis E, listeriosis, cholera), STIs (chlamydia, gonorrhoea and acute hepatitis B), VBDs (dengue fever, malaria, West Nile fever, Japanese encephalitis and yellow fever) and diseases vaccinated against in the Swedish childhood vaccination programme (pertussis, measles, mumps, rubella, diphtheria) acquired abroad 2009-2013...
2017: PloS One
https://www.readbyqxmd.com/read/28738835/incidence-of-and-risk-factors-for-nephrolithiasis-in-patients-with-gout-and-the-general-population-a-cohort-study
#19
A J Landgren, L T H Jacobsson, U Lindström, T Z S Sandström, P Drivelegka, L Björkman, E Fjellstedt, M Dehlin
BACKGROUND: Nephrolithiasis (NL) is known to be associated with gout, although there are few comparative studies on risk and risk factors for NL in gout compared to population cohorts. In this cohort study we investigated: (1) overall incidence of NL in gout (cases) and general population controls; (2) risk and risk factors (common comorbidities and medications) for first-time NL in cases and controls separately. METHODS: Cases (n = 29,968) and age-matched and sex-matched controls (n = 138,678) were identified from the regional healthcare database in western Sweden (VEGA)...
July 24, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28736487/development-blocks-in-innovation-networks-the-swedish-manufacturing-industry-1970-2007
#20
Josef Taalbi
The notion of development blocks (Dahmén, 1950, 1991) suggests the co-evolution of technologies and industries through complementarities and the overcoming of imbalances. This study proposes and applies a methodology to analyse development blocks empirically. To assess the extent and character of innovational interdependencies between industries the study combines analysis of innovation biographies and statistical network analysis. This is made possible by using data from a newly constructed innovation output database for Sweden...
2017: Journal of Evolutionary Economics
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