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https://www.readbyqxmd.com/read/28631955/cerebrospinal-fluid-neurofilament-light-concentration-in-motor-neuron-disease-and-frontotemporal-dementia-predicts-survival
#1
Tobias Skillbäck, Niklas Mattsson, Kaj Blennow, Henrik Zetterberg
OBJECTIVE: To aid diagnostics, patient stratification and studies seeking to find treatments for the related diseases motor neuron disease (MND) and frontotemporal dementia (FTD), there is a need to establish a way to assess disease severity and the amount of ongoing neurodegeneration. Previous studies have suggested that cerebrospinal fluid (CSF) neurofilament light (NFL) may serve this purpose. METHODS: We cross-referenced the Swedish mortality registry with the laboratory database at Sahlgrenska University Hospital to produce a dataset of CSF NFL concentrations and mortality information for 715 MND patients, 87 FTD patients, and 107 healthy controls...
February 6, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28628548/clinical-outcome-measures-for-lateropulsion-poststroke-an-updated-systematic-review
#2
Ryan Koter, Sara Regan, Caitlin Clark, Vicki Huang, Melissa Mosley, Erin Wyant, Chad Cook, Jeffrey Hoder
BACKGROUND AND PURPOSE: Contraversive Lateropulsion, also referred to as contraversive pushing, pusher behavior, and pusher syndrome, can be associated with increased hospital length of stay, increased health care costs, and delayed outcomes in persons with stroke. The purpose of this updated systematic review was to identify scales used to classify contraversive lateropulsion, investigate literature that addresses their clinimetric properties, and create a resource for clinicians recommending use in clinical practice...
July 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28628524/experiences-of-non-specialist-nurses-caring-for-patients-and-their-significant-others-undergoing-transitions-during-palliative-end-of-life-cancer-care-a-systematic-review
#3
Hrønn Thorn, Lisbeth Uhrenfeldt
BACKGROUND: Non-specialist nurses, who are providing palliative end-of-life cancer care to patients and significant others undergoing psychosocial and existential transitions, may experience dissatisfaction, frustration and sorrow. On the other hand, they may also experience happiness, increased knowledge and personal growth. OBJECTIVE/QUESTION: What are non-specialist nurses' experiences when providing palliative end-of-life cancer care that involves the psychosocial and existential transitions of their patients and significant others? INCLUSION CRITERIA TYPES OF PARTICIPANTS: The current review considered studies that included a description of the experiences of non-specialist trained registered nurses (RNs) working in non-specialist wards...
June 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28627923/examination-of-the-triarchic-assessment-procedure-for-inconsistent-responding-in-six-non-english-language-samples
#4
Shannon E Kelley, Josanne D M van Dongen, M Brent Donnellan, John F Edens, Hedwig Eisenbarth, Andrea Fossati, Katarina Howner, Antonella Somma, Karolina Sörman
The Triarchic Assessment Procedure for Inconsistent Responding (TAPIR; Mowle et al., 2016) was recently developed to identify inattentiveness or comprehension difficulties that may compromise the validity of responses on the Triarchic Psychopathy Measure (TriPM; Patrick, 2010). The TAPIR initially was constructed and cross-validated using exclusively English-speaking participants from the United States; however, research using the TriPM has been increasingly conducted internationally, with numerous foreign language translations of the measure emerging...
June 19, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28617565/psychotropic-medications-in-swedish-homicide-victims-and-offenders-a-forensic-toxicological-case-control-study-of-adherence-and-recreational-use
#5
Jonatan Hedlund, Jonas Forsman, Joakim Sturup, Thomas Masterman
OBJECTIVE: We aimed to assess the extent to which adherence to, and recreational use of, psychotropic medications influence the risk of homicide offending and victimization. METHODS: We conducted a population-based case-control study by way of linking a nationwide registry of dispensed prescriptions with a forensic-toxicological database. Homicide victims (n = 200) and offenders (n = 105) were identified for the years 2007-2009 and vehicle-accident controls (n = 1,643) for the years 2006-2013...
June 6, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28614430/effects-of-the-application-of-therapeutic-massage-in-children-with-cancer-a-systematic-review
#6
Juan Rodríguez-Mansilla, Blanca González-Sánchez, Silvia Torres-Piles, Jorge Guerrero Martín, María Jiménez-Palomares, Macarena Núñez Bellino
Objective: to learn about the effects of the use of therapeutic massage in children with cancer. Method: systematic review of controlled clinical trials The search was conducted in November 2014 in the following databases: Pubmed, CSIC, Dialnet, Scopus, Cochrane and PEDro. Inclusion criteria were: clinical trials, published in English or Spanish, analyzing the effects of massage on the different stages and types of childhood cancer (between 1 and 18 years old). Results: of 1007 articles found, 7 met the inclusion criteria...
June 8, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28582282/improved-treatment-and-control-of-hypertension-in-swedish-primary-care-results-from-the-swedish-primary-care-cardiovascular-database
#7
Charlotte Holmquist, Jan Hasselström, Kristina Bengtsson Boström, Karin Manhem, Björn Wettermark, Per Hjerpe, Thomas Kahan
OBJECTIVE: To study temporal trends in hypertension treatment and control in Swedish primary care, in relation to clinical characteristics, comorbidity, and drug treatment. MATERIALS AND METHODS: Repeated cross-sectional analysis of 43 239 hypertensive patients attending primary care in 2001-2002 and of 62 407 patients in 2007-2008. RESULTS: Mean blood pressure (BP) 2007-2008 was 143/79 mmHg in women and 142/81 mmHg in men. Cardiovascular comorbidity and diabetes were present in 13 and 15% of women, and in 18 and 20% of men...
June 2, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28569436/sociodemographic-physical-mental-and-social-factors-in-the-cessation-of-breastfeeding-before-6-months-a-systematic-review
#8
REVIEW
Elisabeth Mangrio, Karin Persson, Ann-Cathrine Bramhagen
BACKGROUND: The World Health Organization recommends exclusive breastfeeding as the main source of nutrition for infants during their first 6 months of life. However, despite this well-known recommendation, not all mothers breastfeed, whether partly or fully, during this time. OBJECTIVE: The aim of this systematic literature review was to compile evidence regarding sociodemographic, physical, mental and social factors that influence breastfeeding mothers to stop breastfeeding before the infant reaches 6 months...
June 1, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28543706/using-a-spontaneous-profile-rather-than-stimulation-test-makes-the-kigs-idiopathic-growth-hormone-deficiency-model-more-accessible-for-clinicians
#9
Karel Duchén, Anders Lindberg, Kaire Kiplok, Berit Kriström
AIM: Children treated with a growth hormone (GH) for idiopathic growth hormone deficiency (IGHD) may be monitored with the first-year prediction model from the Pfizer International Growth Database (KIGS) using auxology, age, GH dose and the maximum GH concentration from a stimulation test (GHmax stim). We tested the hypothesis that using a 12-hour spontaneous profile (GHmax 12h) would be as accurate. METHODS: We studied 98 prepubertal Swedish children (78 boys) aged 2-12 years enrolled in KIGS...
May 22, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28510633/obesity-and-diabetes-as-risk-factors-for-severe-plasmodium-falciparum-malaria-results-from-a-swedish-nationwide-study
#10
Katja Wyss, Andreas Wångdahl, Maria Vesterlund, Ulf Hammar, Saduddin Dashti, Pontus Naucler, Anna Färnert
Background: Noncommunicable diseases and obesity are increasing in prevalence globally, also in populations at risk of malaria. We sought to investigate if comorbidity, in terms of chronic diseases and obesity, is associated with severe Plasmodium falciparum malaria. Methods: We performed a retrospective observational study in adults (≥18 years) diagnosed with malaria in Sweden between January 1995 and May 2015. We identified cases through the surveillance database at the Public Health Agency of Sweden and reviewed clinical data from 18 hospitals...
May 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28509335/dignity-conserving-care-actions-in-palliative-care-an-integrative-review-of-swedish-research
#11
REVIEW
Carina Werkander Harstäde, Karin Blomberg, Eva Benzein, Ulrika Östlund
BACKGROUND: Previous research has proposed that persons in need of palliative care often have a loss of functions and roles that affects social and existential self-image. Moreover, these individuals also commonly suffer from complex multisymptoms. This, together with the situation of facing an impending death, can lead to a loss of dignity. Therefore, supporting these persons' dignity is a crucial challenge for professional nurses. The 'Dignity Care Intervention' addresses the multidimensionality of dignity by identifying patients' dignity-related concerns and suggests care actions to address them...
May 16, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/28485763/dynamiken-i-f%C3%A3-rskrivningen-av-opioider-i-sverige-2000%C3%A2-2015-markanta-omf%C3%A3-rdelningar-inom-opioidgruppen-men-ingen-%C3%A2-epidemi%C3%A2
#12
Emmanuel Bäckryd, Markus Heilig, Mikael Hoffmann
Opioid prescription changes in Sweden 2000-2015 In contrast to the well-established »opioid epidemic« in the US, very little is known about how the prescription of opioids in Sweden has developed during the last decade. Aggregated data from the open Statistical database of the Swedish Board of Health and Welfare were analyzed descriptively. The yearly prevalence of opioid prescription did not change 2006-2015, but there were dramatic shifts in the choice of opioids. During this period, dextropropoxyphene was pulled off the market...
May 2, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28470087/antihypertensive-control-and-new-onset-atrial-fibrillation-results-from-the-swedish-primary-care-cardiovascular-database-spccd
#13
Georgios Mourtzinis, Linus Schiöler, Thomas Kahan, Kristina Bengtsson Boström, Per Hjerpe, Jan Hasselström, Karin Manhem
Background Atrial fibrillation is associated with increased cardiovascular morbidity and mortality. Hypertension is an important risk factor for the development of atrial fibrillation. Aim This study assessed the relationship between blood pressure control and new-onset atrial fibrillation in hypertensive patients. Methods and results We followed 45,530 hypertensive patients with no previously documented atrial fibrillation, attending primary healthcare in Sweden during 2001-2008. After a mean follow-up of 3...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28447839/the-whorfian-time-warp-representing-duration-through-the-language-hourglass
#14
Emanuel Bylund, Panos Athanasopoulos
How do humans construct their mental representations of the passage of time? The universalist account claims that abstract concepts like time are universal across humans. In contrast, the linguistic relativity hypothesis holds that speakers of different languages represent duration differently. The precise impact of language on duration representation is, however, unknown. Here, we show that language can have a powerful role in transforming humans' psychophysical experience of time. Contrary to the universalist account, we found language-specific interference in a duration reproduction task, where stimulus duration conflicted with its physical growth...
April 27, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28425579/myringoplasty-outcomes-from-the-swedish-national-quality-registry
#15
Malin Berglund, Rut Florentzson, Mattias Fransson, Malou Hultcrantz, Per O Eriksson, Erling Englund, Eva Westman
OBJECTIVES/HYPOTHESIS: Data from patients registered for myringoplasty during 2002 to 2012 in the Swedish National Quality Registry for Myringoplasty. STUDY DESIGN: Both conventional myringoplasty and fat-graft techniques were used aimed at healing the tympanic membrane in noninfected ears. METHODS: Analysis was performed on data in a national database collected from 32 ear, nose, and throat clinics. Surgical procedures and outcomes, and patient satisfaction from a questionnaire were studied...
April 20, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28398288/spatiotemporal-historical-datasets-at-micro-level-for-geocoded-individuals-in-five-swedish-parishes-1813-1914
#16
Finn Hedefalk, Patrick Svensson, Lars Harrie
This paper presents datasets that enable historical longitudinal studies of micro-level geographic factors in a rural setting. These types of datasets are new, as historical demography studies have generally failed to properly include the micro-level geographic factors. Our datasets describe the geography over five Swedish rural parishes, and by linking them to a longitudinal demographic database, we obtain a geocoded population (at the property unit level) for this area for the period 1813-1914. The population is a subset of the Scanian Economic Demographic Database (SEDD)...
April 11, 2017: Scientific Data
https://www.readbyqxmd.com/read/28393354/discrepancy-in-prevalence-of-huntington-s-disease-in-two-swedish-regions
#17
A-K Roos, L Wiklund, K Laurell
BACKGROUND: Huntington's disease (HD) is a neurodegenerative disease with an autosomal dominant pattern of inheritance. The prevalence varies between different geographical regions with an estimated average in Europe of about 6/100 000. Parts of northern Sweden are known to have an accumulation of HD, but no prevalence studies have been undertaken for 50 years. OBJECT: The aim of this study was to estimate the prevalence of HD in the two different Swedish counties of Jämtland and Uppsala and compare them with the reported prevalence in Europe...
April 9, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28384078/risk-of-second-cancer-in-hodgkin-lymphoma-survivors-and-influence-of-family-history
#18
Amit Sud, Hauke Thomsen, Kristina Sundquist, Richard S Houlston, Kari Hemminki
Purpose Although advances in Hodgkin lymphoma (HL) treatment have led to improved disease-free survival, this has been accompanied by an increased risk of second cancers. We sought to quantify the second cancer risks and to investigate the impact of family history. Patients and Methods Using the Swedish Family-Cancer Project Database, we identified 9,522 individuals with primary HL diagnosed between 1965 and 2012. We calculated standardized incidence ratios and cumulative incidence of second cancer in HL survivors and compared the standardized incidence ratios of lung, breast, colorectal, and all second cancers in HL survivors with and without a site-specific family history of cancer...
May 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28374973/cancer-risk-in-patients-with-hepatitis-c-virus-infection-a%C3%A2-population-based-study-in-sweden
#19
Xiangdong Liu, Yanqing Chen, Youxin Wang, Xiaohua Dong, Junming Wang, Jianhua Tang, Kristina Sundquist, Jan Sundquist, Jianguang Ji
Increased risks of certain cancers have been observed in patients with hepatitis C virus (HCV) infection. However, data on other cancer sites/types are lacking. We analyzed systematically the risk of developing 35 common cancers in patients with HCV infection using a nationwide Swedish database. Patients with HCV infection were identified from the Swedish Hospital Inpatient and Outpatient Register and Primary Health Care Database, and followed until the diagnosis of cancer. Standardized incidence ratios (SIRs) were calculated for subsequent 35 common cancer sites/types between 1990 and 2010 in patients with HCV infection in Sweden...
April 4, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28371022/sociodemographic-factors-are-associated-with-utilisation-of-statins-after-ischaemic-stroke-tia
#20
Lukas Geary, Jonas Aronius, Björn Wettermark, Jan Hasselström, Bengt Sjöborg, Mia von Euler
OBJECTIVES: To analyse if there are sociodemographic differences in the utilisation of statins 9-12 months after ischaemic stroke or transitory ischaemic attack. METHODS: Anonymised linkage of registry data on all patients >18 years discharged from the hospitals in Stockholm, Sweden 2006-2010 with diagnosis of ischaemic stroke (ICD-10: I63.0-9) or TIA (ICD-10: G45.9) was performed. Data on hospitalisations and diagnoses were collected from the Stockholm County Council administrative databases on healthcare consumption...
March 2017: International Journal of Clinical Practice
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