Xiulin Zhang, Yang He, Xiaolu Zhang, Bo Fu, Zidai Song, Liang Wang, Rui Fu, Xuancheng Lu, Jin Xing, Jianyi Lv, Meng Guo, Xueyun Huo, Xin Liu, Jing Lu, Xiaoyan Du, Zhongming Ge, Zhenwen Chen, Changlong Li
Helicobacter pylori (H. pylori, Hp) has been designated a class I carcinogen and is closely associated with severe gastric diseases. During colonization in the gastric mucosa, H. pylori develops immune escape by inducing host immune tolerance. The gastric epithelium acts as the first line of defense against H. pylori, with Toll-like receptors (TLRs) in gastric epithelial cells being sensitive to H. pylori components and subsequently activating the innate immune system. However, the mechanism of immune tolerance induced by H...
February 4, 2024: Gastric Cancer