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https://www.readbyqxmd.com/read/29767467/treatment-of-periorbital-dark-circles-comparative-study-of-carboxy-therapy-vs-chemical-peeling-vs-mesotherapy
#1
Naglaa A Ahmed, Salma S Mohammed, Mohammad I Fatani
OBJECTIVE: Evaluation and comparison of the efficacy and safety of 3 different modalities of treatment for dark circles that function via different modes of action. METHODS: In total, 45 female patients with periorbital hyperpigmentation were randomly selected to participate from those attending the outpatient dermatology clinic of Al-Zahraa University Hospital within a 6-month period. Patients were divided into 3 groups, and the groups were subjected to different types of therapy: group A, carboxy therapy; group B, chemical peel; and group C, vitamin C mesotherapy...
May 16, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29739834/the-sea-urchin-diadema-africanum-uses-low-resolution-vision-to-find-shelter-and-deter-enemies
#2
John D Kirwan, Michael J Bok, Jochen Smolka, James J Foster, José Carlos Hernández, Dan-Eric Nilsson
Many sea urchins can detect light on their body surface and some species are reported to possess image-resolving vision. Here we measure the spatial resolution of vision in the long-spined sea urchin Diadema africanum , using two different visual responses: a taxis towards dark objects and an alarm response of spine-pointing towards looming stimuli. For the taxis response we used visual stimuli, which were isoluminant to the background, to discriminate spatial vision from phototaxis. Individual animals were placed in the centre of a cylindrical arena under bright down-welling light, with stimuli of varying angular width placed on the arena wall at pseudorandom directions from the centre...
May 8, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29683695/pigeons-deploy-selective-attention-to-efficiently-learn-a-stagewise-multidimensional-visual-discrimination-task
#3
Olga V Vyazovska, Victor M Navarro, Edward A Wasserman
We trained 8 pigeons ( Columba livia ) on a stagewise go/no-go visual discrimination task of increasing complexity, to document the dynamics of selective attention. We constructed negative compound stimuli (S-s) on the basis of their overall similarity to a positive compound stimulus (S+) along 4 binary-valued dimensions: shape (circle/square), size (large/small), line orientation (horizontal/vertical), and brightness (dark/light). Starting with 1 S+ and 1 S- that differed in all 4 dimensional values, in 3 later steps, we progressively added S-s sharing 1, 2, and finally 3 dimensional values with the S+...
April 2018: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/29663676/a-single-center-pilot-study-evaluating-a-novel-trihex-peptide-and-botanical-containing-eye-treatment-compared-to-baseline
#4
Alex Reivitis, Kian Karimi, Chester Griffiths, Ashley Banayan
BACKGROUND: Topical treatments containing tripeptide and hexapeptide (TriHex technology) have been proven to contribute to youthful skin by clearing the extracellular matrix and stimulating collagen and elastin production. OBJECTIVE: Evaluate the efficacy of a novel eye treatment containing TriHex peptides and other synergistic ingredients for the daily treatment of fine lines/crow's feet around the eyes, under eye hollowing, under eye bags, and dark circles. PATIENTS/METHODS: In this study, 10 subjects (9 female and 1 male) aged 30-60 of Fitzpatrick skin type I, II, or III were selected to use an eye treatment containing TriHex peptides and active botanicals (Alastin Restorative Eye Treatment with TriHex Technology™, ALASTIN Skincare, Inc...
April 16, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29432778/-looking-at-nothing-during-sequential-sensorimotor-actions-long-term-memory-based-eye-scanning-of-remembered-target-locations
#5
Rebecca M Foerster
Before acting humans saccade to a target object to extract relevant visual information. Even when acting on remembered objects, locations previously occupied by relevant objects are fixated during imagery and memory tasks - a phenomenon called "looking-at-nothing". While looking-at-nothing was robustly found in tasks encouraging declarative memory built-up, results are mixed in the case of procedural sensorimotor tasks. Eye-guidance to manual targets in complete darkness was observed in a task practiced for days beforehand, while investigations using only a single session did not find fixations to remembered action targets...
March 2018: Vision Research
https://www.readbyqxmd.com/read/29336116/the-retina-of-the-collared-peccary-pecari-tajacu-structure-and-function
#6
Raaya Ezra-Elia, Maya Ross, Nili Avni-Magen, Asaf Berkowitz, Ron Ofri
OBJECTIVE: To study retinal morphology and function in the collared peccary, an ungulate species distantly related to the domestic pig. ANIMAL STUDIES: Twenty captive peccaries anesthetized for routine health examinations. Procedures No abnormalities were noted on a complete ophthalmic examination. Fundi were examined ophthalmoscopically and photographed. The eyes of an individual that died of unrelated, nonocular reasons were studied histologically and by immunohistochemistry...
January 16, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29135036/prospective-studies-of-the-efficacy-and-safety-of-the-picosecond-755-1-064-and-532-nm-lasers-for-the-treatment-of-infraorbital-dark-circles
#7
Monique J Vanaman Wilson, Isabela T Jones, Joanna Bolton, Lisa Larsen, Douglas C Wu, Mitchel P Goldman
BACKGROUND: Infraorbital dark circles result from a combination of factors. The fractionated picosecond 755 nm alexandrite laser and dual wavelength picosecond Nd:YAG laser have not been examined as a method of addressing infraorbital hyperpigmentation. OBJECTIVE: To determine the efficacy and safety of treatment of infraorbital dark circles using fractionated picosecond 755 nm and dual wavelength picosecond Nd:YAG laser. METHODS AND MATERIALS: These trials did not utilize a comparative design; rather, these were separate, prospective, open-label, evaluator-blinded trials utilizing two treatment regimens: (i) 19 adult subjects were treated in a single session with the dual wavelengths of 532 nm and 1,064 nm in consecutive passes using the fractionated lens; (ii) 10 adult subjects were treated using the picosecond 755 nm laser via the fractionated lens in three treatment sessions at 3 week intervals...
January 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29108546/cosmetic-concerns-among-men
#8
REVIEW
Marc Zachary Handler, David J Goldberg
Men are interested in reducing signs of aging, while maintaining a masculine appearance. A chief concern among men is maintenance of scalp hair. Men are also concerned with reducing under eye bags and dark circles. The concern of feminization is of significant importance. Neuromodulators remain the most common cosmetic procedure performed in men. Men often prefer a reduction in facial rhytids, as opposed to elimination of the lines. Softening facial lines in men is meant to maintain an appearance of wisdom, without appearing fragile...
January 2018: Dermatologic Clinics
https://www.readbyqxmd.com/read/29037661/antisense-oligonucleotide-therapy-rescues-disruptions-in-organization-of-exploratory-movements-associated-with-usher-syndrome-type-1c-in-mice
#9
Tia N Donaldson, Kelsey T Jennings, Lucia A Cherep, Adam M McNeela, Frederic F Depreux, Francine M Jodelka, Michelle L Hastings, Douglas G Wallace
Usher syndrome, Type 1C (USH1C) is an autosomal recessive inherited disorder in which a mutation in the gene encoding harmonin is associated with multi-sensory deficits (i.e., auditory, vestibular, and visual). USH1C (Usher) mice, engineered with a human USH1C mutation, exhibit these multi-sensory deficits by circling behavior and lack of response to sound. Administration of an antisense oligonucleotide (ASO) therapeutic that corrects expression of the mutated USH1C gene, has been shown to increase harmonin levels, reduce circling behavior, and improve vestibular and auditory function...
February 15, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29022956/ultrasound-evaluation-of-normal-orbital-preseptal-thickness
#10
A Shrestha, S Shrestha, P Koirala, B Pun
INTRODUCTION: Orbital preseptal thickness is an important parameter not only in diagnosis of orbital cellulitis but also in recent classification and management of dark eye circle (DEC). OBJECTIVE: The aim of this study was to evaluate normal preseptal thickness and collect baseline data in normal skin in a given population with no orbital pathology. MATERIALS & METHOD: Ultrasound was performed on 42 patients (23 females and 19 males) with clinically normal eyes and orbits for evaluation of normal orbital preseptal thickness...
January 2017: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28963735/in-vivo-evaluation-of-some-biophysical-parameters-of-the-facial-skin-of-indian-women-part-i-variability-with-age-and-geographical-locations
#11
L Colomb, F Flament, A Wagle, D Agrawal
BACKGROUND: India is a large country (a subcontinent) of about 3.3 million km2 that covers large ranges in latitude and longitude. The last Indian census counted about 1.21 billion of inhabitants of many origins, creating a vast human diversity and skin types, the variability of which having been previously established. The present study aimed at deepening this knowledge through a set of biophysical measurements to describe, along the skin ageing process, the specificities of various Indian subjects living in different geographical locations...
February 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28771832/spectracam-%C3%A2-a-new-polarized-hyperspectral-imaging-system-for-repeatable-and-reproducible-in-vivo-skin-quantification-of-melanin-total-hemoglobin-and-oxygen-saturation
#12
A Nkengne, J Robic, P Seroul, S Gueheunneux, M Jomier, K Vie
BACKGROUND: An accurate way to determine skin pigmentation is to acquire the spectral reflectance of a skin sample and to quantify chromophores by reverse calculation from physical models of light propagation. Therefore, we tested a new hyperspectral imaging device and software suite, the SpectraCam® system, and evaluated its accuracy to quantify skin chromophores. METHODS: Validation of the SpectraCam® system was performed by, firstly, comparing the known and the acquired reflectance spectra of color phantoms...
February 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/28689323/a-sensitive-colorimetric-assay-system-for-nucleic-acid-detection-based-on-isothermal-signal-amplification-technology
#13
Bo Hu, Jing Guo, Ying Xu, Hua Wei, Guojie Zhao, Yifu Guan
Rapid and accurate detection of microRNAs in biological systems is of great importance. Here, we report the development of a visual colorimetric assay which possesses the high amplification capabilities and high selectivity of the rolling circle amplification (RCA) method and the simplicity and convenience of gold nanoparticles used as a signal indicator. The designed padlock probe recognizes the target miRNA and is circularized, and then acts as the template to extend the target miRNA into a long single-stranded nucleotide chain of many tandem repeats of nucleotide sequences...
August 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28622082/comparing-the-effectiveness-of-fractional-co2-laser-and-the-combination-therapy-with-micro-needling-and-topical-10-trichloroacetic-acid-to-remove-infra-orbital-dark-circles-in-tehran-women
#14
Abbas Zamanian, Mahba Azizi, Mohamadreza Ghasemi, Elham Behrangi, Sedigheh Naeji
BACKGROUND: Infra-orbital dark circles in now identified as a cosmetic problem which should be considered in treatment issue. The present study aimed to assess and compare the clinical efficiency of the combination of micro-needling and 10% trichloroacetic acid (TCA) cream as well as carbon dioxide laser in the management of infra-orbital dark circles. METHODS: This randomized clinical trial was performed on women ranged 28 to 62 years that complained of infra-orbital dark circles...
June 16, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28501377/structural-changes-associated-with-delayed-dark-adaptation-in-age-related-macular-degeneration
#15
Inês Laíns, John B Miller, Dong H Park, Edem Tsikata, Samaneh Davoudi, Safa Rahmani, Jonathan Pierce, Rufino Silva, Teresa C Chen, Ivana K Kim, Demetrios Vavvas, Joan W Miller, Deeba Husain
PURPOSE: To examine the relationship between dark adaptation (DA) and optical coherence tomography (OCT)-based macular morphology in age-related macular degeneration (AMD). DESIGN: Prospective, cross-sectional study. PARTICIPANTS: Patients with AMD and a comparison group (>50 years) without any vitreoretinal disease. METHODS: All participants were imaged with spectral-domain OCT and color fundus photographs, and then staged for AMD (Age-related Eye Disease Study system)...
September 2017: Ophthalmology
https://www.readbyqxmd.com/read/28385012/eosinophilic-encephalomyelitis-in-horses-caused-by-protostrongylid-parasites
#16
Eun-Jung Bak, Young-Hwa Jean, Gye-Hyeong Woo
Four thoroughbred horses showing lameness, ataxia, circling, depression, recumbency, and seizures, were examined. The horses had gross, pale- to dark-red manifestations and foci in the central nervous system (CNS). Multifocal to coalescing eosinophilic necrotizing encephalomyelitis was observed histologically in the CNS along with intact or degenerated nematodes. Nematodes had polymyarian-coelomyarian musculature, a smooth thin cuticle, and intestines lined by multinucleated cells with microvilli. These traits suggested the nematodes belonged to the family Protostrongylidae, which includes Parelaphostrongylus tenuis ...
December 31, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28095138/leber-congenital-amaurosis-from-darkness-to-light-an-ode-to-irene-maumenee
#17
REVIEW
Razek Georges Coussa, Irma Lopez Solache, Robert K Koenekoop
This article is dedicated to Irene Hussels Maumenee, Professor of Human Genetics and Ophthalmology, Johns Hopkins' Wilmer Eye Institute, Ocular Genetics Fellowship director in 1994-1995. Leber congenital amaurosis (LCA) has almost come full circle, from a profound and molecularly uncharacterized form of congenital retinal blindness to one in which a large number of causative genes and disease pathways are known, and the world's first human retinal disease to be treated by gene therapy. Dr. Maumenee's insights, efforts, and leadership have contributed significantly to this remarkable scientific journey...
January 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28047321/tu-ab-bra-04-an-investigation-of-metal-artifact-effects-in-multi-modalities-development-of-mri-ct-heterogeneous-head-and-neck-phantom-for-mri-ct-registration
#18
M Lee, K Song, B Choe, T Suh
PURPOSE: The purpose of this investigation was to develop an CT-MR head and neck phantom which can investigate dose calculation differences between density-assigned MRI and CT, and to compare non-implant inserted registered MR-CT registered image with artifact reduced image of MR-CT registered image. It is to identify potential limitations related to dental implants of MR image and CT image and maximize the advantages to find interactive method to use registered image. METHODS: The phantom comprises half-circled shape which shaped to simulated the anatomical structures of a human head and neck...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27799805/clinical-effects-of-an-oral-supplement-rich-in-antioxidants-on-skin-radiance-in-women
#19
Marion Dumoulin, David Gaudout, Benoit Lemaire
BACKGROUND: Environmental factors impact the skin aging resulting in decrease of skin radiance. Nutrition and particularly antioxidants could help to fight against skin degradation. OBJECTIVE: The aim of this study was to evaluate the effects of an oral supplement rich in specific antioxidants, SkinAx 2TM , on the improvement of the skin radiance in women. METHODS: The open-label clinical study enrolled 35 women, aged 40-70, with facial dull complexion...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27721911/periorbital-hyperpigmentation-in-patients-with-xanthelasma-palpebrarum-an-interesting-observation
#20
Eftychia Platsidaki, Anargyros Kouris, Efthymia Agiasofitou, Christina Antoniou, Georgios Kontochristopoulos
Background: Xanthelasma palpebrarum refers to xanthomas that occur more often near the inner canthus of the eyelid. Periorbital hyperpigmentation presents as a dark area surrounding the eyelids. Objective: In the present study, the authors examined the prevalence and the associated factors of periorbital hyperpigmentation among patients with xanthelasma. Methods: One hundred and fourteen patients with xanthelasma palpebrarum were examined for the presence of dark circles. Detailed questionnaires regarding the history of diabetes, hypothyroidism, smoking status, and weight were completed by all patients...
April 2016: Journal of Clinical and Aesthetic Dermatology
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