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Vitreous syneresis

Manreet Alangh, Varun Chaudhary, Christopher McLaughlin, Brian Chan, Sarah J Mullen, Joshua Barbosa
OBJECTIVE: To characterize emergency department (ED) referrals in order to identify the most common pathologies, compare accuracy of diagnosis, and measure correlation of visual acuity (VA) and intraocular pressure (IOP) measurements between the ED and ophthalmology setting. DESIGN, SETTING, AND PARTICIPANTS: Retrospective chart review of consecutive patients referred for an ocular emergency after hours to a tertiary care emergency eye clinic in Hamilton, Ontario, between February 17, 2015, and May 3, 2015 (n = 288)...
June 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
M S Spitzer, K Januschowski
BACKGROUND AND PURPOSE: The vitreous body is the largest component of the eye. It is a colorless, gelatinous, highly hydrated matrix that fills the posterior segment of the eye between the lens, the ciliary body and the retina. Changes in vitreal structure that occur with aging, such as vitreous liquefaction and fiber aggregation (vitreous syneresis) are important in the pathogenesis of many vitreoretinal diseases. During senescence, the vitreous volume is reduced, the vitreous body collapses and the vitreal fibers are continuously thickened, become more tortuous and surrounded by liquefied vitreous...
July 2015: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Ferenc Kuhn, Bill Aylward
This article represents a synthesis of an extensive literature review and the authors' decades-long personal experience with both scleral buckling (SB) and vitrectomy for rhegmatogenous retinal detachment (RD). Presenting a coherent understanding of the pathophysiology and treatment of RD, the authors confirm numerous findings described in earlier publications but also challenge certain long-standing dogmas. The key argument made here is that it is extremely rare for the chain of events leading to an RD to start with a retinal pathology...
2014: Ophthalmic Research
M Golubovic
AIM: The aim of the paper was to present the efficacy and indications for application of conventional surgical treatment of retinal detachment by using external implants, that is,application of encircling band and buckle. MATERIAL AND METHOD: This study comprised patients from the University Eye Clinic in Skopje. A total of 33 patients were diagnosed and surgically treated in the period between May 2010 and August 2011. Conventional surgery was applied in smaller number of patients whose changes of the vitreous body were manifested by detachment of posterior hyaloid membrane, syneresis, with appearance of a small number of pigment cells in the vitreous body and synchysis, and the very retina was with fresh detachment without folds or epiretinal changes (that is, PVR A grade)...
2013: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
B M Stoffelns, J Vetter, A Keicher, A Mirshahi
BACKGROUND: The aim of this study was to evaluate the role of vitrectomy in patients with visually disturbing vitreous opacities. PATIENTS AND METHODS: A retrospective analysis of the patient characteristics and the outcome of all pseudophacic eyes, which consecutively received in the decade 1996 to 2005 20 G pars plana vitrectomy for visually disturbing floaters, was carried out at the Mainz University Eye Clinic. RESULTS: Forty-one eyes of 32 patients (63 % university graduates, median age: 64 years) were included in the study...
April 2011: Klinische Monatsblätter Für Augenheilkunde
Julien J Labruyère, Claudia Hartley, Katherine Rogers, Graham Wetherill, J Fraser McConnell, Ruth Dennis
Vitreous degeneration is common in dogs and may be associated with cataract formation. Vitreous degeneration may be identified using B-mode ultrasonography and appears as multiple, small, motile, point-like echoes within the vitreous cavity. In humans, vitreous degeneration has also been observed in normal aging eyes but the incidence of vitreous degeneration in dogs without cataract has not previously been documented. The purpose of this study was to describe the ultrasonographic appearance of vitreous degeneration and to investigate its incidence in a population of dogs without cataract or other apparent eye disease...
March 2008: Veterinary Radiology & Ultrasound
T J Bridges, C K Patel, A R Strnad, O R Wood, E S Brewer, D B Karlin
In carbon dioxide laser surgery of the vitreous a process of vaporization has been advocated. In this report syneresis, a thermal liquefaction of gel, is shown to be over ten times more efficient on an energy basis than vaporization. Syneresis of vitreous is experimentally shown to be a first-order kinetic process with an activation energy of 41 +/- 0.5 kilocalories per mole. A theory of laser surgery in which this figure is used agrees closely with results from laser experiments on human eye-bank vitreous...
March 11, 1983: Science
Sarah P Meredith, Allan J Richards, Declan W Flanagan, John D Scott, Arabella V Poulson, Martin P Snead
AIM: To detail the clinical findings in a British family with molecularly characterised Wagner syndrome. BACKGROUND: Only in the last year has the specific genetic defect in Wagner syndrome been identified, and the background literature of the molecular genetics is outlined. Clinical and laboratory findings in a second case of Wagner syndrome are included to highlight difficulties that can be encountered when identifying pathogenic mutations for disorders arising in complex genes...
May 2007: British Journal of Ophthalmology
S Suri, R Banerjee
Dysfunction of the vitreous humor, present in the posterior cavity of the eye, leads to its detachment from the retina and vision loss. In this study, biopolymers were evaluated as in situ gels for short term vitreous substitution. Biophysical characterization revealed that the viscosity of the vitreous was >4000 cP at a shear rate of 0.15/s and it formed a gel with elastic modulus G' greater than the viscous modulus G''. Biopolymers of gellan and hyaluronic acid (8:2 w/w, 1% concentration) were low viscosity liquids at 37 degrees C and gelation was triggered both by the addition of 0...
December 1, 2006: Journal of Biomedical Materials Research. Part A
Seong Eun Kyung, Moo Hwan Chang, Jun Young Ji
Hereditary vitreoretinopathies are potentially blinding inherited disorders characterized by an abnormal-appearing vitreous gel and associated retinal changes. Four of these disorders, Stickler's syndrome, Wagner's disease, erosive vitreoretinopathy, and Goldmann-Favre syndrome, exhibit marked syneresis of the vitreous gel. Erosive vitreoretinopathy has associated retinal pigment epithelial changes, poor night vision, visual field defects, and abnormal electroretinographic findings; symptoms not found in Stickler's syndrome...
June 2002: Korean Journal of Ophthalmology: KJO
Marcin Czajka, Krystyna Pecold
The aim of using enzymes in vitreoretinal surgery is to facility PVD and create pharmacological vitrectomy. It can be achieved by liquefying the gel structure of the vitreous (synchisis) and weakening of adherence of the posterior vitreous cortex to retina (syneresis). The article reviews currently used enzymes in vitreoretinal surgery (plasmin, hyaluronidase, dispase, chondroitinase, collagenase, urokinase, TPA--tissue plasminogen activator) and presents potential profits and side-effects related to their use...
2002: Klinika Oczna
D O Skvorchenko, I P Khoroshilova-Maslova, L D Andreeva, I Kh Sharafetdinov, M I Shtil'man, I A Maklakova, D G Uzunian
The capacity of water-soluble polymers (polyethylenimine, polyvinylpyrrolidone with copolymers) to induce posterior detachment of the vitreous by its rapid condensation (vitreosynerysis) was studied in experiments on 14 rabbits. Histological studies showed that water-soluble polymers specifically react forming complexes with components of the vitreous. The vitreous shrinks under the effect of polyelectrolytes (vitreosynerysis), which leads to its posterior detachment 1.5 h after injection of the polymer into the vitreous cavity: complete detachment was attained in 2 animals and partial in 8...
May 2001: Vestnik Oftalmologii
D M Brown, A E Kimura, T A Weingeist, E M Stone
PURPOSE: Vitreoretinopathies are disorders characterized by an abnormal vitreous gel structure and associated retinal changes. The authors report a pedigree with vitreous changes characteristic of the vitreoretinopathies, but with retinal pigment epithelial changes, electroretinographic abnormalities, and a clinical course distinct from previously described entities. METHODS: Twenty-six family members were examined. Complete ophthalmologic examinations, electroretinography, and perimetry were performed on patients who were at genetic risk for the disease...
April 1994: Ophthalmology
A Kakehashi, N Ueno, B Chakrabarti
Vitreous gel contraction and syneresis, commonly associated with age- and disease-related posterior vitreous detachment (PVD), were induced by a hematoporphyrin (HP)-photosensitized reaction. Calf vitreous gel was irradiated by white light in the presence of HP. Gel weights of the vitreous samples after 24 h of irradiation decreased by 14%, the irradiated control without HP by 8% and the control with HP stored in the dark by 8%. No significant difference in vitreous gel compressibility was found between the irradiated controls and the irradiated samples...
1994: Ophthalmic Research
L Kolozsvári
Three groups of five rabbits each received intravitreal injections of 0.2 ml silicone oil, 0.2 ml physiological saline solution and 0.7 ml air, respectively. Needling of the vitreous body was carried out in three control animals. Changes in the vitreous were monitored by echography. According to our observations the vitreous tolerates all of these substances very well. However, syneresis and sometimes vitreous detachment are likely to occur.
December 1981: Klinische Monatsblätter Für Augenheilkunde
S Hamidi-Toosi, I H Maumenee
Eighteen patients had ocular changes associated with spondyloepiphyseal dysplasia congenita, a rare cause of congenital dwarfism with normal mental development. Seven patients had nonprogressive myopia of 5.00 or more diopters. Vitreoretinal degeneration was encountered in six patients with high myopia, and vitreous syneresis was present in all patients. Corrected visual acuity was 20/50 or better in all patients. Retinal detachment was not encountered, although reports in the nonophthalmic literature claim up to 50% retinal detachment rate and poor visual prognosis in these patients...
July 1982: Archives of Ophthalmology
J H Sheets, E L Wasserman
No abstract text is available yet for this article.
October 1984: CLAO Journal: Official Publication of the Contact Lens Association of Ophthalmologists, Inc
R J Thresher, M Ehrenberg, R Machemer
We have developed a simple technique in rabbit and baboon eyes that utilizes intravitreally injected perfluoropropane gas, which expands slowly to efficiently compress and displace nearly completely the vitreous body. There is cataract formation after extended contact of the gas bubble with the lens. However, it is rapidly reversible by reducing the duration of lens contact (gas-fluid exchange) and by using young animals. No long-term alterations in intraocular pressure or retinal function were observed, as determined by electroretinography, during the 4-month test period...
1984: Graefe's Archive for Clinical and Experimental Ophthalmology
J R Wolter
The eye of a 60-year-old man with a clinically very successful lens implant became available for pathological study after a very sudden and uncomplicated death about 6 months following cataract surgery. The following changes were found: slight non-granulomatous uveitis associated with foreign-body reaction to the lens implant and its supporting iris suture, absence of the anterior vitreous face, advanced syneresis of the central vitreous, vitreous hemorrhage with diffuse layering of erythrocytes on the inner aspect of the remaining vitreous crust, vitreous traction on peripheral and central retina with tenting of foveal internal limiting membrane, and some foveal edema without cystoid changes and without foveolar detachment...
1983: Graefe's Archive for Clinical and Experimental Ophthalmology
B Miller, H Miller, S J Ryan
Perfluoropropane gas was injected into the vitreous body of a primate eye. Clinical and morphologic studies revealed that the gas bubble created a large cavity within the vitreous. The cavity that subsequently filled with viscous liquid was completely enveloped by vitreous gel, thus simulating the clinical condition known as vitreous syneresis. The shell of residual vitreous, which was much thicker inferiorly and behind the lens than superiorly, seemed to be an intact and continuous layer. In spite of the extensive syneresis, posterior vitreous detachment failed to develop...
September 1985: Archives of Ophthalmology
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