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p-Synephrine, naringin, hesperidin, resting metabolic rate, heart rate, blood pressure

Sidney J Stohs, Harry G Preuss, Samuel C Keith, Patti L Keith, Howard Miller, Gilbert R Kaats
Bitter orange (Citrus aurantium) extract is widely used in dietary supplements for weight management and sports performance. Its primary protoalkaloid is p-synephrine. Most studies involving bitter orange extract and p-synephrine have used products with multiple ingredients. The current study assessed the thermogenic effects of p-synephrine alone and in conjunction with the flavonoids naringin and hesperidin in a double-blinded, randomized, placebo-controlled protocol with 10 subjects per treatment group. Resting metabolic rates (RMR), blood pressure, heart rates and a self-reported rating scale were determined at baseline and 75 min after oral ingestion of the test products in V-8 juice...
2011: International Journal of Medical Sciences
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