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https://www.readbyqxmd.com/read/28300872/impacts-of-albumin-synergized-with-hydroxyethyl-starch-on-early-microvascular-albumin-leakage-after-major-abdominal-surgery-in-rabbits
#1
Weiming Li, Pengyuan Xu, Yunyun Cen, Dali Sun, Ting Yang, Qingwen Xu, Shumin Li, Yijun Li, Bo Ding
PURPOSE: To investigate the impacts of albumin synergized with hydroxyethyl starch (HES) on early microvascular albumin leakage after major abdominal surgery in rabbits. METHODS: Forty male Japanese rabbits were randomly divided into four groups: the control group, the saline group, the albumin group, and the Syn group (hydroxyethyl starch+albumin). The latter three groups were performed gastrectomy plus resection of pancreatic body and tail and splenectomy. The serum albumin concentration was detected before and 48h after surgery, and the conditions of mesenteric microvascular leakage in these 4 groups were observed under microscope 48 h after surgery to calculate the leakage rate...
February 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28297691/-intraoperative-artery-wall-stimulating-electromyography-during-microvascular-decompression-surgery-to-treat-hemifacial-spasm-a-case-report
#2
Ryotaro Yamashita, Taishi Nakamura, Ryutaro Fukuyama, Kosuke Ishikawa, Takahiro Hayashi, Ryohei Miyazaki, Makoto Ohtake, Mitsuru Sato, Kensuke Tateishi, Nobuyuki Shimizu, Jun Suenaga, Hidetoshi Murata
OBJECTIVE: Microvascular decompression(MVD)surgery has been established as a standard treatment for hemifacial spasm. However, because decompression surgery results in unfavorable outcomes in some cases, a more critical monitoring strategy is required. To improve surgical outcome for hemifacial spasms, abnormal muscle response(AMR)has been proposed as a tool for intraoperative electrophysiological monitoring during MVD surgery. Here, we report a single case of surgical MVD monitoring using artery wall stimulating electromyography(AWS-EMG)...
March 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28293502/microvascular-fragment-transplantation-improves-rat-dorsal-skin-flap-survival
#3
Randolph Stone, Christopher R Rathbone
BACKGROUND: The development of flap necrosis distally remains a concern during microsurgical flap transfers because, at least in part, of decreased perfusion. Microvascular fragments (MVFs) are microvessels isolated from adipose tissue that are capable of improving tissue perfusion in a variety of tissue defects. The aim of this study was to determine whether the transplantation of MVFs in a dorsal rat skin flap model can improve flap survival. METHODS: A 10 × 3 cm flap was raised in a cranial to caudal fashion on the dorsal side of 16 Lewis rats, with the caudal side remaining intact...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28276721/relationship-between-different-subpopulations-of-circulating-cd4-t-lymphocytes-and-microvascular-or-systemic-oxidative-stress-in-humans
#4
Carolina De Ciuceis, Claudia Agabiti-Rosei, Claudia Rossini, Paolo Airò, Mirko Scarsi, Angela Tincani, Guido Alberto Massimo Tiberio, Silvia Piantoni, Enzo Porteri, Leonardo Solaini, Sarah Duse, Francesco Semeraro, Beatrice Petroboni, Luigi Mori, Maurizio Castellano, Alice Gavazzi, Enrico Agabiti-Rosei, Damiano Rizzoni
BACKGROUND AND OBJECTIVE: Different components of the immune system, including innate and adaptive immunity (T effector lymphocytes and T regulatory lymphocytes - TREGs) may be involved in the development of hypertension, vascular injury and inflammation. However, no data are presently available in humans about possible relationships between T-lymphocyte subtypes and microvascular oxidative stress. Our objective was to investigate possible relationships between T-lymphocyte subtypes and systemic and microvascular oxidative stress in a population of normotensive subjects and hypertensive patients...
February 15, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28272727/-an-unusual-presentation-of-painful-tic-convulsive
#5
S Romano-Feinholz, M P Medina, F E Nares-Lopez, J L Soto-Hernandez, R Revuelta-Gutierrez
INTRODUCTION: The term 'painful tic convulsive' is used to describe the syndrome involving concomitant hemifacial spasm and ipsilateral trigeminal neuralgia. Vascular compression of the fifth and seventh cranial nerves is the most common cause, involving the entry and exit zone of rootlets coming from the brainstem; nevertheless, different etiologies of this syndrome has been previously reported. Treatment for this disease is based on surgical microvascular decompression of the nerve rootlets, but still a topic of debate...
March 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28267121/current-techniques-for-postoperative-monitoring-of-microvascular-free-flaps
#6
Nasir Khatri, Shuhao Zhang, Santosh S Kale
Free tissue transfer (FTT) is used in patients with complicated reconstructive needs; it can provide stable wound coverage, improved aesthetic appearance, and restore functional deficits. Despite the high success rates of free flaps, vascular occlusion is a significant risk leading to flap failure. Many studies have demonstrated that the salvage rate for flaps is inversely related to the time between onset of a vascular problem and its surgical correction. As a result, ongoing postoperative monitoring of free flaps for adequate perfusion is imperative to allow timely and accurate diagnosis of vascular compromise...
March 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28260292/-anatomy-and-management-of-superior-petrosal-vein-in-microvascular-decompression-for-trigeminal-neuralgia
#7
Y M Yang, Z W Wang, Z Cui, H Z Jiang, C Sha, Q G Yuan, H W Xie, D M Wang
Objective: To investigate the characteristics of superior petrosal vein (SPV) and its influence on the surgical field in microvascular decompression (MVD) for trigeminal neuralgia (TN), and to analyze the effect of the surgical treatment of SPV on the surgical approach, indication and prognosis. Methods: The clinical data of 280 patients with trigeminal neuralgia between Jan. 2013 and Jun. 2016 were collected, including the trunks and the branches of SPV, intraoperative electrocoagulation status, the surgery outcome and complications...
February 21, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28254601/electromyographically-guided-nerve-combing-makes-microvascular-decompression-more-successful-in-hemifacial-spasm-with-persistent-abnormal-muscle-response
#8
Xin Zhang, Jin Zhu, Yin-Da Tang, Hua Zhao, Ting-Ting Ying, Yan Yuan, Shi-Ting Li
BACKGROUND: Microvascular decompression (MVD) of the facial nerve monitored intra-operatively by abnormal muscle response (AMR) activity is a common treatment for hemifacial spasm. However, AMR frequently persists after MVD, for which electromyographically (EMG)-guided nerve combing is sometimes recommended. Because no research regarding the success of EMG-guided nerve combing has been published, we compared the effectiveness of nerve combing after MVD with simple MVD in cases including persistent AMR...
February 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28237791/long-term-incidence-of-microvascular-disease-after-bariatric-surgery-or-usual-care-in-patients-with-obesity-stratified-by-baseline-glycaemic-status-a-post-hoc-analysis-of-participants-from-the-swedish-obese-subjects-study
#9
Lena M S Carlsson, Kajsa Sjöholm, Cecilia Karlsson, Peter Jacobson, Johanna C Andersson-Assarsson, Per-Arne Svensson, Ingrid Larsson, Stephan Hjorth, Martin Neovius, Magdalena Taube, Björn Carlsson, Markku Peltonen
BACKGROUND: Bariatric surgery is associated with remission of diabetes and prevention of diabetic complications in patients with obesity and type 2 diabetes. Long-term effects of bariatric surgery on microvascular complications in patients with prediabetes are unknown. The aim of this study was to examine the effects of bariatric surgery on incidence of microvascular complications in patients with obesity stratified by baseline glycaemic status. METHODS: Patients were recruited to the Swedish Obese Subjects (SOS) study between Sept 1, 1987, and Jan 31, 2001...
February 22, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28237789/microvascular-complications-after-metabolic-surgery
#10
George K Dimitriadis, Harpal S Randeva, Alexander D Miras
No abstract text is available yet for this article.
February 22, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28216817/turned-in-fasciocutaneous-island-flap-from-face-and-neck-based-on-subdermal-microcirculation-for-reconstruction-of-the-oral-cavity-following-cancer-surgery
#11
Kalpesh Jayantkumar Gajiwala
BACKGROUND: The skin and soft tissues of the face and neck have a rich plexus of dermal-subdermal vessels, which creates the possibility of raising a fasciocutaneous flap based on this vascular supply. A turned in fasciocutaneous island flap (TIFCIF) from an adjacent area of the defect can provide a simple substitute to many complex reconstructive procedures. MATERIALS AND METHODS: Fifteen patients underwent wide excision for oral cancer and upper neck dissection, maintaining bone framework, between August 2010 and June 2014...
September 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28205070/clinicopathological-significance-of-ganglioside-dsgb5-expression-in-renal-cell-carcinoma
#12
Jun Itoh, Akihiro Ito, Shuichi Shimada, Yoshihide Kawasaki, Narihiko Kakoi, Hideo Saito, Koji Mitsuzuka, Mika Watanabe, Makoto Satoh, Seiichi Saito, Yoichi Arai
Disialosyl globopentaosylceramide (DSGb5) is a ganglioside originally isolated from tissue extracts of renal cell carcinoma (RCC) with metastasis. Previous in vitro experiments have suggested that DSGb5 promotes metastasis by enhancing the migration of RCC cells and downregulating NK cell cytotoxicity against RCC cells. In this study, we investigated the clinicopathological significance of DSGb5 expression in RCC and outcomes of RCC patients. A total of 156 RCC patients who underwent surgical treatments at our hospital from January 2007 through December 2012 were analyzed in this study...
February 15, 2017: Glycoconjugate Journal
https://www.readbyqxmd.com/read/28199000/overexpression-of-pregnane-x-and-glucocorticoid-receptors-and-the-regulation-of-cytochrome-p450-in-human-epileptic-brain-endothelial-cells
#13
Chaitali Ghosh, Mohammed Hossain, Jesal Solanki, Imad M Najm, Nicola Marchi, Damir Janigro
OBJECTIVE: Recent evidence suggests a metabolic contribution of cytochrome P450 enzymes (CYPs) to the drug-resistant phenotype in human epilepsy. However, the upstream molecular regulators of CYP in the epileptic brain remain understudied. We therefore investigated the expression and function of pregnane xenobiotic (PXR) and glucocorticoid (GR) nuclear receptors in endothelial cells established from post-epilepsy surgery brain samples. METHODS: PXR/GR localization was evaluated by immunohistochemistry in specimens from subjects who underwent temporal lobe resections to relieve drug-resistant seizures...
February 15, 2017: Epilepsia
https://www.readbyqxmd.com/read/28198595/free-microvascular-rotationplasty-with-nerve-repair-for-rhabdomyosarcoma-in-a-18-month-old-patient
#14
Alberto Pérez-García, Marta Salom, María Eloísa Villaverde-Doménech, Francisco Baixauli, Eduardo Simón-Sanz
Rotationplasty is a limb-sparing surgical option in lower limb malignancies. Sciatic or tibial nerve encasement has been considered an absolute contraindication to this procedure. We report a case of an 18-month-old girl with a rhabdomyosarcoma that affected the leg and popliteal fossa, with neurovascular involvement. Knee and proximal leg intercalary resection was performed followed by reconstruction with free microvascular rotationplasty and neurorraphy from tibial division of sciatic nerve to sural and tibial nerves, and from saphenous nerve to superficial peroneal nerve...
February 15, 2017: Microsurgery
https://www.readbyqxmd.com/read/28177337/free-flap-loss-caused-by-heparin-induced-thrombocytopenia-and-thrombosis-hitt-a-case-report-and-literature-review
#15
E Segna, A R Bolzoni, C Baserga, A Baj
Heparin-induced thrombocytopenia and thrombosis (HITT) represents a dramatic condition that is difficult to diagnose because of nuanced clinical presentation. Therefore, in every case of microvascular thrombosis during heparin-therapy prompt suspicion about HITT is necessary to avoid flap necrosis. We present a case of HITT which, as the 8 other articles reviewed, clearly shows that HITT is difficult to diagnose and complex to manage. Microvascular reconstruction is the first choice in head and neck reconstruction; unfortunately, dramatic outcomes in free flap surgery due to unpredictable thrombotic events are still reported in the English literature...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28154776/portal-vein-tumor-thrombus-is-a-bottleneck-in-the-treatment-of-hepatocellular-carcinoma
#16
Ju-Xian Sun, Jie Shi, Nan Li, Wei-Xing Guo, Meng-Chao Wu, Wan-Yee Lau, Shu-Qun Cheng
The effect of portal vein tumor thrombus (PVTT) on the prognosis of patients with hepatocellular carcinoma has become clear over the past several decades. However, identifying the mechanisms and performing the diagnosis and treatment of PVTT remain challenging. Therefore, this study aimed to summarize the progress in these areas. A computerized literature search in Medline and EMBASE was performed with the following combinations of search terms: "hepatocellular carcinoma" AND "portal vein tumor thrombus." Although several signal transduction or molecular pathways related to PVTT have been identified, the exact mechanisms of PVTT are still largely unknown...
December 2016: Cancer Biology & Medicine
https://www.readbyqxmd.com/read/28153619/the-effects-of-dual-abnormal-muscle-response-monitoring-on-microvascular-decompression-in-patients-with-hemifacial-spasm
#17
Xin Zhang, Hua Zhao, Ting-Ting Ying, Yin-Da Tang, Jin Zhu, Shi-Ting Li
BACKGROUND: Microvascular decompression (MVD) is the most useful treatment for hemifacial spasm (HFS). During MVD surgery, traditional abnormal muscle response (tAMR) is widely used to monitor success in decompressing the facial nerve. Dual AMR (dAMR) is a new monitoring method used during MVD for HFS. We compared the sensitivities and reliabilities of tAMR and dAMR. METHODS: We performed a retrospective study of 1,301 cases of HFS treated using MVD between January 2014 and March 2016...
January 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28151027/end-to-end-versus-end-to-side-anastomoses-in-free-flap-reconstruction-single-centre-experiences
#18
Paul I Heidekrueger, Milomir Ninkovic, Albrecht Heine-Geldern, Frank Herter, P Niclas Broer
BACKGROUND: The choice of microsurgical anastomotic technique, end-to-end (ETE) or end-to-side (ETS), is a relevant point in free tissue transfer. The decision-making process of choosing ETE or ETS technique depends on several clinical and perioperative factors. This study evaluates the outcomes of microvascular procedures in a large single centre patient series, focusing on ETE vs ETS arterial anastomoses. MATERIALS AND METHODS: Between January 2009 and June 2015, 838 patients underwent free flap surgery for reconstruction after trauma, infection, or malignancies...
February 2, 2017: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/28144579/microvascular-response-to-transfusion-in-elective-spine-surgery
#19
J Matthias Walz, Ottokar Stundner, Federico P Girardi, Bruce A Barton, Aimee R Koll-Desrosiers, Stephen O Heard, Stavros G Memtsoudis
AIM: To investigate the microvascular (skeletal muscle tissue oxygenation; SmO2) response to transfusion in patients undergoing elective complex spine surgery. METHODS: After IRB approval and written informed consent, 20 patients aged 18 to 85 years of age undergoing > 3 level anterior and posterior spine fusion surgery were enrolled in the study. Patients were followed throughout the operative procedure, and for 12 h postoperatively. In addition to standard American Society of Anesthesiologists monitors, invasive measurements including central venous pressure, continual analysis of stroke volume (SV), cardiac output (CO), cardiac index (CI), and stroke volume variability (SVV) was performed...
January 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28121209/combined-treatment-with-intravitreal-bevacizumab-and-laser-photocoagulation-for-exudative-maculopathy-in-facioscapulohumeral-muscular-dystrophy
#20
Rita Matos, João Beato, Marta Silva, Sérgio Silva, Elisete Brandão, Fernando Falcão-Reis, Susana Penas
PURPOSE: To report a rare case of exudative maculopathy in a patient with facioscapulohumeral muscular dystrophy (FSHD), and its management. METHODS: Observational case report. RESULTS: A 62-year-old man with genetically confirmed FSHD was referred to our department complaining of decreased visual acuity in his left eye. At presentation, right eye examination was unremarkable and best-corrected visual acuity (BCVA) was 20/20. Left eye BCVA was 20/100 and it presented a dense cataract with the evidence of macular lipid exudation...
January 25, 2017: Ophthalmic Genetics
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