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Jeffrey B Cooper, Barry S Issenberg, Michael A DeVita, Ronnie Glavin
No abstract text is available yet for this article.
October 2016: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
Tomasz M Beer, Vinay Prasad
No abstract text is available yet for this article.
September 15, 2016: JAMA Oncology
Chantal M I Beijersbergen, Urs Granacher, Martijn Gäbler, Paul DeVita, Tibor Hortobágyi
INTRODUCTION: Slow gait predicts many adverse clinical outcomes in old adults but the mechanisms of how power training can minimize the age-related loss of gait velocity is unclear. We examined the effects of 10 weeks of lower extremity power training and detraining on healthy old adults' lower extremity muscle power and gait kinematics. METHODS: As part of the Potsdam Gait Study (POGS), participants started with 10 weeks of power training followed by 10 weeks of detraining (n = 16) and participants started with a 10-week control period followed by 10 weeks of power training (n = 16)...
August 30, 2016: Medicine and Science in Sports and Exercise
Jason T Jakiela, Paul DeVita, Daniel P Beavers, Stephen P Messier
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Stephen P Messier, David F Martin, Shannon L Mihalko, Edward H Ip, Paul DeVita, D Wayne Cannon, Monica Munsey, Danielle Beringer, Santiago Saldana, Rebecca E Fellin, Joseph F Seay
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Azzour D Hazzan, Candice Halinski, Sofia Agoritsas, Steven Fishbane, Maria V DeVita
Advanced CKD is a period of CKD that differs greatly from earlier stages of CKD in terms of treatment goals. Treatment during this period presents particular challenges as further loss of kidney function heralds the need for renal replacement therapy. Successful management during this period increases the likelihood of improved transitions to ESRD. However, there are substantial barriers to optimal advanced CKD care. In this review, we will discuss advanced CKD definitions and epidemiology and outcomes.
July 2016: Advances in Chronic Kidney Disease
Maria V DeVita
No abstract text is available yet for this article.
July 2016: Advances in Chronic Kidney Disease
Tanjim Sultana, Maria V DeVita, Michael F Michelis
PURPOSE: Functional iron deficiency (FID) is a major cause of persistent anemia in dialysis patients and also contributes to a suboptimal response to erythropoietin (Epo) administration. Vitamin C acts as an enzyme cofactor and enhances mobilization of the ferrous form of iron to transferrin thus increasing its bioavailability. High-dose intravenous vitamin C has been shown to decrease the Epo requirement and improve hemoglobin levels in previous studies. This study assessed the effect of low-dose oral vitamin C on possible reduction in Epo dose requirements in stable hemodialysis patients with FID...
September 2016: International Urology and Nephrology
Michael A DeVita, Clifton W Callaway, Charissa Pacella, Maria Mori Brooks, John Lutz, Susan Stuart
BACKGROUND: In the United States, organ donation after circulatory death (DCD) determination is increasing among those who are removed from life-sustaining therapy but is rare when death is unexpected. We created a program for uncontrolled DCD (uDCD). METHODS: A comprehensive program was created to train personnel to identify and respond quickly to potential donors after unexpected death. The process termed Condition T was implemented in the emergency department (ED) of 2 academic medical centers...
March 2016: Progress in Transplantation
Dale S Hardy, Devita T Stallings, Jane T Garvin, Francine C Gachupin, Hongyan Xu, Susan B Racette
BACKGROUND: To determine the best anthropometric discriminators of type 2 diabetes (T2DM) among White and Black males and females in a large U.S. SAMPLE: HASH(0x3acc2c8) METHODS: We used Atherosclerosis Risk in Communities study baseline data (1987-1989) from 15242 participants (1827 with T2DM) aged 45-65 years. Anthropometric measures included a body shape index (ABSI), body adiposity index (BAI), body mass index (BMI), waist circumference (WC), waist to height ratio (WHtR), and waist to hip ratio (WHR)...
April 23, 2016: Journal of Diabetes
Angela L Rollins, Marina Kukla, Gary Morse, Louanne Davis, Michael Leiter, Maria Monroe-DeVita, Mindy E Flanagan, Alissa Russ, Sara Wasmuth, Johanne Eliacin, Linda Collins, Michelle P Salyers
OBJECTIVES: Prior research found preliminary effectiveness for Burnout Reduction: Enhanced Awareness, Tools, Handouts, and Education (BREATHE), a daylong workshop for reducing burnout among behavioral health providers. Using a longer follow-up compared with prior research, this study compared the effectiveness of BREATHE and a control condition. METHODS: Behavioral health providers (N=145) from three U.S. Department of Veterans Affairs facilities and two social service agencies were randomly assigned to BREATHE or person-centered treatment planning...
August 1, 2016: Psychiatric Services: a Journal of the American Psychiatric Association
Vincent T DeVita, George P Canellos
This article highlights the important collaboration between the U.S. NCI in Bethesda, Maryland and the Istituto Tumori in Milan, Italy that had a major impact on the development of curative regimens for breast cancer, Hodgkin's disease and diffuse large B cell lymphoma.In addition to his contribution to developing new therapies, Gianni Bonadonna played an important role in bringing highly focused, disciplined, ethical clinical trials to the European continent.
March 2016: Tumori
Vincent T DeVita
No abstract text is available yet for this article.
March 2016: Oncology (Williston Park, NY)
Paul DeVita, Patrick Rider, Tibor Hortobágyi
A consensus exists that high knee joint forces are a precursor to knee osteoarthritis and weight loss reduces these forces. Because large weight loss also leads to increased step length and walking velocity, knee contact forces may be reduced less than predicted by the magnitude of weight loss. The purpose was to determine the effects of weight loss on knee muscle and joint loads during walking in Class III obese adults. We determined through motion capture, force platform measures and biomechanical modeling the effects of weight loss produced by gastric bypass surgery over one year on knee muscle and joint loads during walking at a standard, controlled velocity and at self-selected walking velocities...
March 2016: Gait & Posture
Vincent T DeVita, Elizabeth DeVita-Raeburn, John H Moxley
No abstract text is available yet for this article.
March 15, 2016: Cancer Research
Michaele B Manigrasso, Jinhong Pan, Vivek Rai, Jinghua Zhang, Sergey Reverdatto, Nosirudeen Quadri, Robert J DeVita, Ravichandran Ramasamy, Alexander Shekhtman, Ann Marie Schmidt
The receptor for advanced glycation endproducts (RAGE) binds diverse ligands linked to chronic inflammation and disease. NMR spectroscopy and x-ray crystallization studies of the extracellular domains of RAGE indicate that RAGE ligands bind by distinct charge- and hydrophobicity-dependent mechanisms. The cytoplasmic tail (ct) of RAGE is essential for RAGE ligand-mediated signal transduction and consequent modulation of gene expression and cellular properties. RAGE signaling requires interaction of ctRAGE with the intracellular effector, mammalian diaphanous 1 or DIAPH1...
2016: Scientific Reports
Vincent DeVita, Peter Wehrwein
No abstract text is available yet for this article.
January 2016: Managed Care
Tibor Hortobágyi, Patrick Rider, Allison H Gruber, Paul DeVita
PURPOSE: Old compared with young adults walk with reduced ankle and increased hip mechanical output. We examined the idea that age, leg strength, or both are related to the age-related changes in mechanical output during gait. METHODS: Healthy young (n = 32, age 21.5 years) and old adults (n = 32, age 76.8 years) participated in biomechanical gait analyses at 1.5 m/s and were also measured for maximal leg strength. RESULTS: Analysis 1 confirmed previous data as old compared with young adults walked with 50 % more hip positive work and 18 % less ankle positive work...
April 2016: European Journal of Applied Physiology
George Canellos, Vincent DeVita
No abstract text is available yet for this article.
November 2015: Oncologist
Rebecca Krupenevich, Patrick Rider, Zachary Domire, Paul DeVita
Females in the military sustain a higher incidence of lower extremity injuries compared to males. Previous investigations of gender differences during load carriage used loads normalized to body mass; as a result of anthropometric and strength differences between genders, this may partially normalize to strength, masking gender or size differences in response to load. We compared gait kinetics and kinematics between genders based on a standardized load, instead of loads relative to body mass. 11 males and 11 females walked at 1...
September 2015: Military Medicine
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