keyword
MENU ▼
Read by QxMD icon Read
search

skeletal muscle and exercise

keyword
https://www.readbyqxmd.com/read/28640773/salivary-mitochondrial-dna-copy-number-is-associated-with-exercise-ventilatory-efficiency
#1
Yang Chen, Helene Z Hill, Gudrun Lange, Michael J Falvo
Chen, Y, Hill, HZ, Lange, G, and Falvo, MJ. Salivary mitochondrial DNA copy number is associated with exercise ventilatory efficiency. J Strength Cond Res 31(7): 2000-2004, 2017-Mitochondrial DNA copy number (mtDNAcn) is an index of mitochondrial content and is responsive to changes in exercise training volume. Therefore, assessment of mtDNAcn may help to optimize exercise prescription and aid in athlete monitoring. Although previous work has assessed mtDNAcn derived from skeletal muscle and blood using invasive approaches, no study has examined salivary mtDNAcn and its relationship with sport performance...
July 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28631758/bioengineered-constructs-combined-with-exercise-enhance-stem-cell-mediated-treatment-of-volumetric-muscle-loss
#2
Marco Quarta, Melinda Cromie, Robert Chacon, Justin Blonigan, Victor Garcia, Igor Akimenko, Mark Hamer, Patrick Paine, Merel Stok, Joseph B Shrager, Thomas A Rando
Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current treatments show limited efficacy. Here we show that bioconstructs suffused with genetically-labelled muscle stem cells (MuSCs) and other muscle resident cells (MRCs) are effective to treat VML injuries in mice. Imaging of bioconstructs implanted in damaged muscles indicates MuSCs survival and growth, and ex vivo analyses show force restoration of treated muscles. Histological analysis highlights myofibre formation, neovascularisation, but insufficient innervation...
June 20, 2017: Nature Communications
https://www.readbyqxmd.com/read/28631582/effect-of-green-tea-extract-supplementation-on-glycogen-replenishment-in-exercised-human-skeletal-muscle
#3
Tsen-Wei Tsai, Chia-Chen Chang, Su-Fen Liao, Yi-Hung Liao, Chien-Wen Hou, Jung-Piao Tsao, I-Shiung Cheng
The purpose of this study was to investigate the effects of 8-week green tea extract (GTE) supplementation on promoting postexercise muscle glycogen resynthesis and systemic energy substrate utilisation in young college students. A total of eight healthy male participants (age: 22·0 (se 1·0) years, BMI: 24·2 (se 0·7) kg/m2, VO2max: 43·2 (se 2·4) ml/kg per min) participated in this study. GTE (500 mg/d for 8 weeks) was compared with placebo in participants in a double-blind/placebo-controlled and crossover study design with an 8-week washout period...
June 20, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28628078/nociceptor-interleukin-10-receptor-1-is-critical-for-muscle-analgesia-induced-by-repeated-bouts-of-eccentric-exercise-in-the-rat
#4
Pedro Alvarez, Oliver Bogen, Paul G Green, Jon D Levine
Delayed-onset muscle soreness is typically observed after strenuous or unaccustomed eccentric exercise. Soon after recovery, blunted muscle soreness is observed on repeated eccentric exercise, a phenomenon known as repeated bout effect (RBE). Although regular physical activity decreases muscle hyperalgesia, likely because of increased production of the anti-inflammatory cytokine interleukin-10 (IL-10) in the skeletal muscle, whether IL-10 also contributes to the antinociceptive effect of RBE is unknown. Furthermore, whether IL-10 attenuates muscle hyperalgesia by acting on muscle nociceptors remains to be established...
April 26, 2017: Pain
https://www.readbyqxmd.com/read/28625951/evaluation-of-supplementing-active-peptide-s-effect-on-recovering-skeletal-muscle-micro-injury-after-track-and-field-exercises
#5
Caifeng Li, Zongyou Yang
To explore the effect of supplementing active peptide on recovering skeletal muscle injury after track and field exercises. METHOD: choose 80 patients (contain teenagers) with skeletal muscle micro-injury after the track and field exercises from March 2015 to July 2016, divide them into two groups. Normal treatment of micro-injury of skeletal muscle is given to the control group while active peptide is supplemented to the experimental group based on normal treatment. Compare the two groups to find the differences in relevant indexes of skeletal muscle after track and field exercises...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28624852/vasoconstrictor-responsiveness-in-contracting-human-muscle-influence-of-contraction-frequency-contractile-work-and-metabolic-rate
#6
Nicholas T Kruse, William E Hughes, Kenichi Ueda, Darren P Casey
PURPOSE: The aim of this study was to examine whether independent effects exist between contractile work and metabolic demand (VO2m) on vasoconstrictor responsiveness (i.e., functional sympatholysis) under different contraction durations matched for total contractile work in exercising human skeletal muscle. METHODS: Ten young men performed rhythmic forearm contractions at 10 and 15% of maximum voluntary contraction (MVC) which consisted of muscle contractions using the same duty cycle but altering the duration of the contraction-relaxation cycles of exercise and included: 1) fast frequency contractions at 10% MVC (FFC10%) using a contraction relaxation cycle at 1:2 s; 2) slow frequency contractions at 10% MVC (SFC10%) at 2:4 s; and 3) SFC at 15% MVC (SFC15%) at 2:4 s...
June 17, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28623559/ifn-%C3%AE-induced-reactive-oxygen-species-and-mitochondrial-damage-contribute-to-muscle-impairment-and-inflammation-maintenance-in-dermatomyositis
#7
Alain Meyer, Gilles Laverny, Yves Allenbach, Elise Grelet, Vanessa Ueberschlag, Andoni Echaniz-Laguna, Béatrice Lannes, Ghada Alsaleh, Anne Laure Charles, François Singh, Joffrey Zoll, Evelyne Lonsdorfer, François Maurier, Olivier Boyer, Jacques-Eric Gottenberg, Anne Sophie Nicot, Jocelyn Laporte, Olivier Benveniste, Daniel Metzger, Jean Sibilia, Bernard Geny
Dermatomyositis (DM) is an autoimmune disease associated with enhanced type I interferon (IFN) signalling in skeletal muscle, but the mechanisms underlying muscle dysfunction and inflammation perpetuation remain unknown. Transcriptomic analysis of early untreated DM muscles revealed that the main cluster of down-regulated genes was mitochondria-related. Histochemical, electron microscopy, and in situ oxygraphy analysis showed mitochondrial abnormalities, including increased reactive oxygen species (ROS) production and decreased respiration, which was correlated with low exercise capacities and a type I IFN signature...
June 16, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28623435/the-brain-behaves-as-a-muscle
#8
Marinella Coco
It is known that lactate accumulates in the skeletal muscle during intense anaerobic exercise but is rapidly cleared from the muscles when they resume aerobic metabolism; however, at least some lactate reaches the blood stream. It has been observed that during maximal exercise, blood lactate increases with transport of the blood to the brain. This could be interpreted as a mechanism to protect against possible "central fatigue" in times of maximal activity during the course of which the lactate would preserve the functionality of the primary cortical motor and sensory areas, even at the expense of the efficiency of the other structures...
June 16, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28618190/relation-between-upper-limb-muscle-strength-with-exercise-capacity-quality-of-life-and-dyspnea-in-patients-with-severe-chronic-obstructive-pulmonary-disease
#9
Dicle Kaymaz, İpek Çaylı Candemir, Pınar Ergün, Neşe Demir, Filiz Taşdemir, Pervin Demir
OBJECTIVES: In chronic obstructive pulmonary disease (COPD), skeletal muscle weakness is characterized by reduced muscle strength, reduced muscle endurance, and the presence of muscle fatigue, especially in the lower limbs; there has been little research into upper limb skeletal muscles. In this study we aimed to investigate the relation of upper limb muscle strength with pulmonary function, exercise capacity, quality of life, and dyspnea sensation. METHODS: Eigthy-eight patients (89...
June 15, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28617704/greater-oxidative-capacity-in-primary-myotubes-from-endurance-trained-women
#10
Timothy D Heden, Terence E Ryan, Patrick J Ferrara, Robert C Hickner, Patricia M Brophy, P Darrell Neufer, Joseph M McClung, Katsuhiko Funai
PURPOSE: Exercise training promotes skeletal muscle mitochondrial biogenesis and an increase in maximal oxygen consumption. Primary myotubes retain some metabolic properties observed in vivo but it is unknown whether this includes exercise-induced mitochondrial adaptations. The goal of this study was to test if primary myotubes from exercise-trained women have higher mitochondrial content and maximal oxygen consumption compared to untrained women. METHODS: Six trained and nine untrained Caucasian women participated in this study...
June 14, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28614843/elementary-school-teachers-vocal-dose-muscle-bioenergetics-and-training-implications
#11
Audrey G Smith, Mary J Sandage, David D Pascoe, Laura W Plexico, Italo R Lima, Guanqun Cao
Purpose: Translating exercise-science methodology for determination of muscle bioenergetics, we hypothesized that the temporal voice-use patterns for classroom and music teachers would indicate a reliance on the immediate energy system for laryngeal skeletal-muscle metabolism. It was hypothesized that the music-teacher group would produce longer voiced segments than the classroom teachers. Method: Using a between- and within-group multivariate analysis-of-variance design (5 classroom teachers; 7 music teachers), we analyzed fundamental-frequency data-collected via an ambulatory phonation monitor-for length (seconds) of voiced and nonvoiced intervals...
June 15, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28608457/potential-therapeutic-interventions-for-chronic-kidney-disease-associated-sarcopenia-via-indoxyl-sulfate-induced-mitochondrial-dysfunction
#12
Yuki Enoki, Hiroshi Watanabe, Riho Arake, Rui Fujimura, Kana Ishiodori, Tadashi Imafuku, Kento Nishida, Ryusei Sugimoto, Saori Nagao, Shigeyuki Miyamura, Yu Ishima, Motoko Tanaka, Kazutaka Matsushita, Hirotaka Komaba, Masafumi Fukagawa, Masaki Otagiri, Toru Maruyama
BACKGROUND: Chronic kidney disease (CKD) patients experience skeletal muscle wasting and decreased exercise endurance. Our previous study demonstrated that indoxyl sulfate (IS), a uremic toxin, accelerates skeletal muscle atrophy. The purpose of this study was to examine the issue of whether IS causes mitochondria dysfunction and IS-targeted intervention using AST-120, which inhibits IS accumulation, or mitochondria-targeted intervention using L-carnitine or teneligliptin, a dipeptidyl peptidase-4 inhibitor which retains mitochondria function and alleviates skeletal muscle atrophy and muscle endurance in chronic kidney disease mice...
June 12, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28608438/a-randomized-clinical-trial-investigating-the-efficacy-of-targeted-nutrition-as-adjunct-to-exercise-training-in-copd
#13
Coby van de Bool, Erica P A Rutten, Ardy van Helvoort, Frits M E Franssen, Emiel F M Wouters, Annemie M W J Schols
BACKGROUND: Evidence regarding the efficacy of nutritional supplementation to enhance exercise training responses in COPD patients with low muscle mass is limited. The objective was to study if nutritional supplementation targeting muscle derangements enhances outcome of exercise training in COPD patients with low muscle mass. METHODS: Eighty-one COPD patients with low muscle mass, admitted to out-patient pulmonary rehabilitation, randomly received oral nutritional supplementation, enriched with leucine, vitamin D, and omega-3 fatty acids (NUTRITION) or PLACEBO as adjunct to 4 months supervised high intensity exercise training...
June 12, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28607132/impaired-muscle-oxygenation-and-elevated-exercise-blood-pressure-in-hypertensive-patients-links-with-vascular-stiffness
#14
Konstantina Dipla, Areti Triantafyllou, Nikolaos Koletsos, Stavros Papadopoulos, Vasileios Sachpekidis, Ioannis S Vrabas, Eugenia Gkaliagkousi, Andreas Zafeiridis, Stella Douma
This study examined in vivo (1) skeletal muscle oxygenation and microvascular function, at rest and during handgrip exercise, and (2) their association with macrovascular function and exercise blood pressure (BP), in newly diagnosed, never-treated patients with hypertension and normotensive individuals. Ninety-one individuals (51 hypertensives and 40 normotensives) underwent office and 24-hour ambulatory BP, arterial stiffness, and central aortic BP assessment, followed by a 5-minute arterial occlusion and a 3-minute submaximal handgrip exercise...
June 12, 2017: Hypertension
https://www.readbyqxmd.com/read/28605657/muscle-as-a-paracrine-and-endocrine-organ
#15
REVIEW
Jimena Giudice, Joan M Taylor
Skeletal muscle cells are highly abundant and metabolically active and are known to 'communicate' their energy demands to other organs through active secretion. Muscle-derived secretory proteins include a variety of cytokines and peptides collectively referred to as 'myokines' that exert autocrine, paracrine or endocrine effects. Analyses of the skeletal muscle secretome revealed that numerous myokines are secreted in response to contraction or strength training, and that these factors not only regulate energy demand but also contribute to the broad beneficial effects of exercise on cardiovascular, metabolic, and mental health...
June 9, 2017: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/28602674/serum-metabolomic-response-to-exercise-training-in-spontaneously-hypertensive-rats
#16
Xiangyang Liu, Yanjun Wang, Rui Gao, Ying Xing, Xiaomiao Li, Zhengjun Wang
Chronic aerobic exercise training exhibits blood pressure protective effects, but the mechanism in metabolic level remains largely unclear. This study aims to investigate the effect of exercise training from serum metabolic profiles on the development of hypertension in spontaneously hypertensive rats (SHRs). Exercise training was performed, and the serum metabolites were measured by integrating gas chromatography-mass spectrometer and correlation-based network analysis. After a period of 6 weeks of chronic aerobic exercise training, systolic blood pressure was significant lower in the exercise training group (SHR + EX) rats than the control group (SHR)...
May 20, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28601950/increase-in-carbon-dioxide-accelerates-the-performance-of-endurance-exercise-in-rats
#17
Takeshi Ueha, Keisuke Oe, Masahiko Miwa, Takumi Hasegawa, Akihiro Koh, Hanako Nishimoto, Sang Yang Lee, Takahiro Niikura, Masahiro Kurosaka, Ryosuke Kuroda, Yoshitada Sakai
Endurance exercise generates CO2 via aerobic metabolism; however, its role remains unclear. Exogenous CO2 by transcutaneous delivery promotes muscle fibre-type switching to increase endurance power in skeletal muscles. Here we determined the performance of rats running in activity wheels with/without transcutaneous CO2 exposure to clarify its effect on endurance exercise and recovery from muscle fatigue. Rats were randomised to control, training and CO2 groups. Endurance exercise included activity-wheel running with/without transcutaneous CO2 delivery...
June 10, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/28601553/skeletal-muscle-water-t2-as-a-biomarker-of-disease-status-and-exercise-effects-in-patients-with-duchenne-muscular-dystrophy
#18
Ami Mankodi, Noura Azzabou, Thomas Bulea, Harmen Reyngoudt, Hirity Shimellis, Yupeng Ren, Eunhee Kim, Kenneth H Fischbeck, Pierre G Carlier
The purpose of this study was to examine exercise effects on muscle water T2 in patients with Duchenne muscular dystrophy (DMD). In 12 DMD subjects and 19 controls, lower leg muscle fat (%) was measured by Dixon and muscle water T2 and R2 (1/T2) by the tri-exponential model. Muscle water R2 was measured again at 3 hours after an ankle dorsiflexion exercise. The muscle fat fraction was higher in DMD participants than in controls (p < .001) except in the tibialis posterior muscle. Muscle water T2 was measured independent of the degree of fatty degeneration in DMD muscle...
April 28, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28597407/resistance-wheel-exercise-from-mid-life-has-minimal-effect-on-sciatic-nerves-from-old-mice-in-which-sarcopenia-was-prevented
#19
Vidya S Krishnan, Zoe White, Jessica R Terrill, Stuart I Hodgetts, Melinda Fitzgerald, Tea Shavlakadze, Alan R Harvey, Miranda D Grounds
The ability of resistance exercise, initiated from mid-life, to prevent age-related changes in old sciatic nerves, was investigated in male and female C57BL/6J mice. Aging is associated with cellular changes in old sciatic nerves and also loss of skeletal muscle mass and function (sarcopenia). Mature adult mice aged 15 months (M) were subjected to increasing voluntary resistance wheel exercise (RWE) over a period of 8 M until 23 M of age. This prevented sarcopenia in the old 23 M aged male and female mice...
June 8, 2017: Biogerontology
https://www.readbyqxmd.com/read/28596299/postexercise-essential-amino-acid-supplementation-amplifies-skeletal-muscle-satellite-cell-proliferation-in-older-men-24%C3%A2-hours-postexercise
#20
Paul T Reidy, Christopher S Fry, Jared M Dickinson, Micah J Drummond, Blake B Rasmussen
Aged skeletal muscle has an attenuated and delayed ability to proliferate satellite cells in response to resistance exercise. The mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway is a focal point for cell growth, however, the effect of postexercise mTORC1 activation on human skeletal muscle satellite cell (SC) proliferation is unknown. To test the proliferative capacity of skeletal muscle SC in aging muscle to a potent mTORC1 activator (i.e., EAA; essential amino acids) we recruited older (~72y) men to conduct leg resistance exercise (8setsx10reps) without (-EAA; n = 8) and with (+EAA: n = 11) ingestion of 10 g of EAA 1 h postexercise...
June 2017: Physiological Reports
keyword
keyword
73920
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"