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water and electrolyte imbalance in oncology

R De las Peñas, Y Escobar, F Henao, A Blasco, C A Rodríguez
Hydroelectrolytic disorders are one of the most common metabolic complications in cancer patients. Although often metabolic alterations affecting various ions are part of the manifestations of the oncological disease, even in the form of paraneoplastic syndrome, we must not forget that very often, these disorders could be caused by various drugs, including some of the antineoplastic agents most frequently used, such as platin derivatives or some biologics. These guidelines review major management of diagnosis, evaluation and treatment of the most common alterations of sodium, calcium, magnesium and potassium in cancer patients...
December 2014: Clinical & Translational Oncology
Jackie Baker, Jaffer Ajani, Florian Scotté, Dorte Winther, Miguel Martin, Matti S Aapro, Gunter von Minckwitz
Docetaxel is an effective treatment approved in five key cancers, but its effectiveness in clinical practice can be compromised by sub-optimal side-effect management. The aim of this review was to investigate the extent of the published work on specific docetaxel-related side effects and to provide, where possible, evidence-based recommendations for their prevention and management. PubMed and the American Society of Clinical Oncology (ASCO) databases were systematically searched for articles published in English over the past 5 and 2 years, respectively, and pertaining to six side effects identified as being common to the majority of docetaxel regimens and indications of particular relevance to the oncology nurse...
July 2008: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
Ramzi Jeddi, Yosr Ben Abdennebi, Bassam Allani, Raihane Belakhal, Lamia Aissaoui, Hela Ben Abid, Zaher Belhadj Ali, Balkis Meddeb
Tumor lysis syndrome is a potentially life threatening oncologic emergency that requires immediate medical intervention. The syndrome results from the destruction (or lysis) of a large number of rapidly dividing malignant cells spontaneously or during chemotherapy. The resulting metabolic abnormalities include hyperkaliemia, hyperuricemia, and hyperphosphatemia with secondary hypocalcemia, all of which put patients at risk for renal failure and alteration in cardiac function. The tumor lysis syndrome occurs most often in patients with large tumor burdens that are very sensitive to chemotherapy and radiotherapy, such as acute or chronic leukaemias with high leukocyte counts and high-grade lymphoma...
February 2007: La Tunisie Médicale
Victor M Valdespino-Gómez, Juan Ramón López-Garza, Julio C González-Alemán, Victor E Valdespino-Castillo
The global incidence of emergencies and urgent medical?surgical conditions in cancer patients has not been well described. The aim of the study was to identify the main symptoms and diagnoses in patients seen for consultation at the Urgent Care Service in a Mexican Comprehensive Cancer Center. This was a retrospective observational study. The information was obtained from the Continuous Admission Service daily consultation records at the Oncology Hospital, National Medical Center "21st Century," Institute of Social Security, Mexico City...
September 2006: Cirugia y Cirujanos
Tatsuya Morita, Ichinosuke Hyodo, Taisuke Yoshimi, Masayuki Ikenaga, Yoichiro Tamura, Akitaka Yoshizawa, Akira Shimada, Tatsuo Akechi, Mitsunori Miyashita, Isamu Adachi et al.
To explore the association between hydration volume and laboratory findings, and between calculated fluid balance and changes in clinical signs of dehydration and fluid retention in terminally ill cancer patients, a secondary analysis of a large multicenter, prospective, observational study was performed. The study enrolled 125 abdominal cancer patients who received laboratory examinations in the last week before death. Patients were classified into two groups: the hydration group (n = 44), who received 1L or more of artificial hydration per day both 1 and 3 weeks before death, and the nonhydration group (n = 81)...
February 2006: Journal of Pain and Symptom Management
Kathleen Colson, Deborah S Doss, Regina Swift, Joseph Tariman, Teri E Thomas
Multiple myeloma (MM), a malignancy of the plasma cells, accounts for an estimated 14% of all newly diagnosed hematologic malignancies. Advances in chemotherapy and stem cell transplantation have improved survival rates, but MM remains incurable. Bortezomib (Velcade, Millennium Pharmaceuticals, Inc., Cambridge, MA), a first-in-class proteasome inhibitor, has been approved for patients with MM who have received at least two prior treatments and have demonstrated disease progression on the most recent one. During clinical trials, most side effects were manageable with standard interventions...
October 2004: Clinical Journal of Oncology Nursing
M L Brigden
Broad categories of emergency hematologic and oncologic situations are metabolic crises, compressions and obstructions, and symptomatic cytopenias. In each instance, a decision to intervene should be made on the basis of findings on diagnostic assessment in combination with prognostic information. Management should be directly proportional to the possibility for cure, significant remission, or improved quality of life. Numerous diseases, including potentially curable cancer, can be modified and patients' quality of life substantially improved with appropriate emergency intervention...
March 2001: Postgraduate Medicine
J Mayer, M Doubek, J Vorlìcek
Fungal infections are an important cause of morbidity and mortality in patients with malignancies. Therefore, the use of amphotericin B (AmB) is essential for these patients. Results from the literature to date show that renal toxicity is the most serious adverse effect of AmB. Renal impairment manifests as a decrease in glomerular filtration and damage to tubular function. Currently, there is no reliable method of preventing nephrotoxicity. We have observed that sodium supplementation alone may not prevent nephrotoxicity...
January 1999: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
A D Clark, S McKendrick, P J Tansey, I M Franklin, R Chopra
No comparative clinical information on the properties of lipid-associated amphotericin preparations is presently available. In this single-centre retrospective analysis over a 5-year period the indications, efficacy and toxicity of true liposomal amphotericin (AmBisome) were compared with a lipid complexed preparation (Abelcet). In a novel approach APACHE III scores were used in addition to neutrophil counts, disease status and additional immunosuppression to accurately assess the severity of illness in both groups and enable valid comparison...
October 1998: British Journal of Haematology
E K Dafnis, M E Laski
No abstract text is available yet for this article.
May 1993: Seminars in Nephrology
I Savatovsky, J L Champagnac, P M Roux
In the operation described the second jejunal loop is isolated through an horizontal incision linking the tips of the 12 th ribs. The ends of the loop are then anastomosed with the sub-pyelic ureters and the resulting V-shaped conduit is brought to the skin. The main complication is a salt-deficiency syndrome due to the physiology of the isolated jejunal loop. The loss of salt may be troublesome in patients with pre-existing renal insufficiency. This syndrome is corrected by oral administration of sodium chloride...
September 3, 1983: La Presse Médicale
J Griffin
No abstract text is available yet for this article.
February 1987: Seminars in Oncology Nursing
P A Akers
Nursing care often jumps from problem identification to proposed interventions, bypassing information gathering and inclusion of all pertinent clinical factors. To promote improvement in medical oncology patient outcomes, two algorithms were developed. Algorithm use does not guarantee a positive outcome, but it does ensure that a standard of care appropriate to a clinical problem will be instituted. Two algorithms for commonly encountered problems of elevated body temperature (hyperthermia) and fluid volume excess are presented...
September 1991: Oncology Nursing Forum
D C Stolinsky
Malignant neoplasms may cause life-threatening complications requiring prompt diagnosis and emergency therapy. Whether or not the underlying neoplasm is potentially curable, the physician can often provide worthwhile prolongation of life and dramatic symptomatic relief. Among the serious complications of neoplasia are superior vena cava obstruction, airway obstruction, pericardial tamponade, spinal cord compression, brain metastasis, meningeal involvement by cancer, hyperuricemia, hypercalcemia and hyperkalemia...
September 1978: Western Journal of Medicine
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