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https://www.readbyqxmd.com/read/29146506/silicone-metacarpophalangeal-arthroplasty-for-osteoarthritis-long-term-results
#1
Nathan T Morrell, Arnold-Peter C Weiss
PURPOSE: To demonstrate that silicone metacarpophalangeal (MCP) arthroplasty provides excellent long-term outcomes with a low complication rate in osteoarthritis patients. METHODS: A consecutive cohort of 35 patients with osteoarthritis of 1 or more MCP joints undergoing anatomically neutral silicone MCP arthroplasty was followed over a 15-year period. Functional outcomes including strength and range of motion (ROM), as well as complications, were recorded. All patients were available for long-term assessment including radiographs and outcomes questionnaire...
November 14, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29145111/a-novel-protein-tyrosine-phosphatase-like-phytase-from-lactobacillus-fermentum-nkn51-cloning-characterization-and-application-in-mineral-release-for-food-technology-applications
#2
Rekha Sharma, Piyush Kumar, Vandana Kaushal, Rahul Das, Naveen Kumar Navani
A novel protein tyrosine phosphatase like phytase (PTPLP), designated as PhyLf from probiotic bacterium Lactobacillus fermentum NKN51 was identified, cloned, expressed and characterized. The recombinant PhyLf showed specific activity of 174.5 U/mg. PhyLf exhibited strict specificity towards phytate and optimum temperature at 60 °C, pH 5.0 and ionic strength of 100 mM. Km and Kcat of PhyLf for phytate were 0.773 mM and 84.31 s(-1), respectively. PhyLf exhibited high resistance against oxidative inactivation...
November 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29138805/extracellular-polysaccharides-purified-from-aureobasidium-pullulans-sm%C3%A2-2001-polycan-inhibit-dexamethasone%C3%A2-induced-muscle-atrophy-in-mice
#3
Jong-Min Lim, Young Joon Lee, Hyung-Rae Cho, Dong-Chan Park, Go-Woon Jung, Sae Kwang Ku, Jae-Suk Choi
The present study assessed the beneficial skeletal muscle‑preserving effects of extracellular polysaccharides from Aureobasidium pullulans SM‑2001 (Polycan) (EAP) on dexamethasone (DEXA)‑induced catabolic muscle atrophy in mice. To investigate whether EAP prevented catabolic DEXA‑induced muscle atrophy, and to examine its mechanisms of action, EAP (100, 200 and 400 mg/kg) was administered orally, once a day for 24 days. EAP treatment was initiated 2 weeks prior to DEXA treatment (1 mg/kg, once a day for 10 days) in mice...
November 10, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29125855/functional-classification-of-grasp-strategies-used-by-hemiplegic-patients
#4
Alicia García Álvarez, Agnès Roby-Brami, Johanna Robertson, Nicolas Roche
This study aimed to identify and qualify grasp-types used by patients with stroke and determine the clinical parameters that could explain the use of each grasp. Thirty-eight patients with chronic stroke-related hemiparesis and a range of motor and functional capacities (17 females and 21 males, aged 25-78), and 10 healthy subjects were included. Four objects were used (tissue packet, teaspoon, bottle and tennis ball). Participants were instructed to "grasp the object as if you are going to use it". Three trials were video-recorded for each object...
2017: PloS One
https://www.readbyqxmd.com/read/29125814/carpometacarpal-fracture-dislocation-of-the-fourth-and-fifth-finger-mid-term-results-of-15-patients
#5
Deniz Gülabi, Mehmet Ali Uysal, Bilgehan Çevik, Bülent Kılıç, Emre Karadeniz
OBJECTIVES: This study aims to retrospectively evaluate and compare the mid-term clinical follow-up results of patients who were treated with open or closed reduction due to carpometacarpal (CMC) fracture dislocation. PATIENTS AND METHODS: Medical charts of 15 patients (1 male, 14 females; mean age 32.5±10.5 years; range 18 to 55 years) who were operated for fourth and fifth finger CMC fracture dislocations were examined. Patients were divided into two groups according to applied treatment as closed reduction and percutaneous pinning (CRPP, n=6) and open reduction and percutaneous pinning (ORPP, n=9)...
December 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/29125747/alchemical-free-energy-calculations-for-nucleotide-mutations-in-protein-dna-complexes
#6
Vytautas Gapsys, Bert L de Groot
Nucleotide sequence dependent interactions between proteins and DNA are responsible for a wide range of gene regulatory functions. Accurate and generalizable methods to evaluate the strength of protein-DNA binding have been long sought after. While numerous computational approaches have been developed, most of them require fitting parameters to experimental data to a certain degree, e.g. machine learning algorithms or knowledge based statistical potentials. Molecular dynamics based free energy calculations offer a robust, system independent, first principles based method to calculate free energy differences upon nucleotide mutation...
November 10, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29123629/effect-of-low-level-laser-therapy-and-strength-training-protocol-on-hand-grip-by-dynamometry
#7
Rafael Barbosa, Alexandre Marcolino, Vitor Souza, Guilherme Bertolino, Marisa Fonseca, Rinaldo Guirro
Introduction: The purpose of this study was to investigate the effect of low-level laser therapy (LLLT) - 660 nm and 904 nm - before grip strength protocol in healthy subjects. Methods: The study included 45 healthy volunteers with an average age of 22.7 (±1.4) years, subdivided into the following groups, control group: grip strength training associated with placebo LLLT; 660 nm group: LLLT (660 nm, 20 J/cm(2), power of 30 mW, and beam area of 0.06 cm(2), continuous, energy 1.2 J, and exposure time 40 seconds per point) before grip strength training and 904 nm group: LLLT (904 nm, 10 J/cm(2), peak power of 70 W and 0...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29118255/the-effect-of-stainless-steel-and-silicone-instruments-on-hand-comfort-and-strength-a-pilot-study
#8
Melanie J Hayes
Purpose: Many dental hygienists experience musculoskeletal pain during the course of their careers, often as a result of the sustained grips on instruments and repetitive movements employed during clinical practice. Current research suggests that lighter instruments with a larger diameter reduce force and load on the hand during scaling procedures; therefore, the texture and weight of silicone handles is designed to decrease the strain placed on the hand and fingers. The purpose of this research is to investigate and compare the effect of silicone instrument handles and traditional stainless steel instrument handles on hand comfort and strength...
April 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29111640/importance-of-substrate-functionality-on-the-adhesion-and-debonding-of-a-pressure-sensitive-adhesive-under-water
#9
Preetika Karnal, Paul Roberts, Stefan Gryska, Courtney King, Carlos Barrios, Joelle Frechette
We investigate the effect of an aqueous environment on the adhesion of a model acrylic pressure sensitive adhesive (PSA) composed of 2-ethylhexylacrylate-co-acrylic acid. We use probe-tack adhesion measurements accompanied by in situ imaging of the contact region during bonding and debonding. Within the probe-tack tests we use both hydrophilic (piranha and plasma treatment) and hydrophobic (C18-silanization) surface treatments to investigate the contribution of probe's surface energy on the underwater adhesion...
November 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29108826/physical-activity-and-autoimmune-diseases-get-moving-and-manage-the-disease
#10
REVIEW
Kassem Sharif, Abdulla Watad, Nicola Luigi Bragazzi, Micheal Lichtbroun, Howard Amital, Yehuda Shoenfeld
Physical activity, by definition, is any skeletal muscle body movement that results in energy expenditure. In the last few decades, a plethora of scientific evidences have accumulated and confirmed the beneficial role of physical activity as a modifiable risk factor for a wide variety of chronic diseases including cardiovascular diseases (CVDs), diabetes mellitus and cancer, among others. Autoimmune diseases are a heterogeneous group of chronic diseases, which occur secondary to loss of self-antigen tolerance...
November 3, 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29097982/evaluating-hand-function-in-clients-with-trigger-finger
#11
Danit Langer, Adina Maeir, Michael Michailevich, Shai Luria
Background: Trigger finger (TF) is a common hand pathology frequently encountered in hand clinics. Occupational therapists predominantly assess TF symptoms as opposed to using standardized hand functioning assessments. The purpose of this study was to assess the construct validity of dexterity and grip strength assessments for clients with TF. Method: Sixty-three participants with TF and 66 healthy controls were administered the Functional Dexterity Test (FDT), Purdue Pegboard Test (PPT), and Jamar® Hydraulic Hand Dynamometer (JD) and completed the Disabilities of Arm Shoulder and Hand questionnaire (DASH)...
2017: Occupational Therapy International
https://www.readbyqxmd.com/read/29074868/lateralized-occipito-temporal-n1-responses-to-images-of-salient-distorted-finger-postures
#12
Miguel G Espírito Santo, Hsin-Yuan Chen, Martin Schürmann
For humans as social beings, other people's hands are highly visually conspicuous. Exceptionally striking are hands in other than natural configuration which have been found to elicit distinct brain activation. Here we studied response strength and lateralization of this activation using event-related potentials (ERPs), in particular, occipito-temporal N1 responses as correlates of activation in extrastriate body area. Participants viewed computer-generated images of hands, half of them showing distorted fingers, the other half showing natural fingers...
October 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29062267/design-and-preliminary-feasibility-study-of-a-soft-robotic-glove-for-hand-function-assistance-in-stroke-survivors
#13
Hong Kai Yap, Jeong Hoon Lim, Fatima Nasrallah, Chen-Hua Yeow
Various robotic exoskeletons have been proposed for hand function assistance during activities of daily living (ADL) of stroke survivors. However, traditional exoskeletons involve the use of complex rigid systems that impede the natural movement of joints, and thus reduce the wearability and cause discomfort to the user. The objective of this paper is to design and evaluate a soft robotic glove that is able to provide hand function assistance using fabric-reinforced soft pneumatic actuators. These actuators are made of silicone rubber which has an elastic modulus similar to human tissues...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29059921/cortical-response-of-the-projected-thumb-tactile-sensation-under-tens-by-meg
#14
Y Chen, M N Li, C Y Cao, X L Zhu, X H Sui
The existence of projected finger territories (PFTs) near the stump provides an essential way to realize the tactile sensation of lost fingers by transcutaneous electrical nerve stimulation (TENS). After amputation, the somatosensory cortex corresponding to lost fingers might be invaded by other cortical areas due to cortical plasticity. However, it was seldom observed how the amputees could feel the projected or lost finger tactile sensation in the cerebral cortex under TENS. To answer this question, by using magnetoencephalography (MEG), we investigated the cortical response under TENS of the projected thumb territory and normal thumb with 2 Hz current pulses...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29056390/atypically-localized-glomus-tumor-causing-anterior-interosseous-nerve-syndrome-a-case-report
#15
Yunus Emre Akman, Merter Yalcinkaya, Yavuz Arikan, Yavuz Kabukcuoglu
This article presents a 48-year-old male patient who presented with pain in the left forearm and weakness and clumsiness in the left hand of 6 months' duration. Flexor motor strength loss of the thumb and the index finger was present and neurophysiologic tests showed findings compatible with axonal injury in the anterior interosseous nerve (AIN) innervated muscles. Magnetic resonance imaging revealed a space-occupying lesion in the proximal forearm resembling a glomus tumor. Excision of the mass and release of the AIN were performed...
October 19, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29051115/an-herbal-formula-consisting-of-schisandra-chinensis-turcz-baill-lycium-chinense-mill-and-eucommia-ulmoides-oliv-alleviates-disuse-muscle-atrophy-in-rats
#16
Seongguk Cho, Riwon Hong, Poorm Yim, Mijung Yeom, Bombi Lee, Woong Mo Yang, Jongki Hong, Hyang Sook Lee, Dae-Hyun Hahm
ETHNOPHARMACOLOGICAL RELEVANCE: Schisandra chinensis (Turcz.) Baill (SC), Lycium chinense Mill (LC) and Eucommia ulmoides Oliv (EU) are representative tonic herbal medicines that help to strengthen body muscles and bones making them stronger according to the Donguibogam, a tradition medical book of the Joseon Dynasty in Korea. AIM OF STUDY: To evaluate effects of an herbal formula consisting of SC, LC and EU on muscle atrophy in C2C12 myotubes and in a rat model of immobilization-induced muscle atrophy...
October 16, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29042331/the-first-experience-of-triple-nerve-transfer-in-proximal-radial-nerve-palsy
#17
Mohammadreza Emamhadi, Sasan Andalib
BACKGROUND: Injury to distal of posterior cord of brachial plexus leads to palsy of the radial and axillary nerves. The symptoms are usually motor deficits of the deltoid muscle, triceps brachii muscle, and the extensor muscles of the wrist, thumb and fingers. Tendon transfers, nerve grafts, and nerve transfers are options of surgical treatment of proximal radial nerve palsy to restore some motor functions. Tendon transfer is painful, requires a long immobilization, and decreases donor muscle strength; nevertheless, nerve transfer produces promising outcome...
October 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29037114/home-based-hand-rehabilitation-with-a-robotic-glove-in-hemiplegic-patients-after-stroke-a-pilot-feasibility-study
#18
Palmira Bernocchi, Chiara Mulè, Fabio Vanoglio, Giovanni Taveggia, Alberto Luisa, Simonetta Scalvini
OBJECTIVE: To evaluate the feasibility and safety of home rehabilitation of the hand using a robotic glove, and, in addition, its effectiveness, in hemiplegic patients after stroke. METHODS: In this non-randomized pilot study, 21 hemiplegic stroke patients (Ashworth spasticity index ≤ 3) were prescribed, after in-hospital rehabilitation, a 2-month home-program of intensive hand training using the Gloreha Lite glove that provides computer-controlled passive mobilization of the fingers...
October 16, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29018976/capillary-loss-on-nailfold-capillary-microscopy-is-associated-with-mortality-in-systemic-sclerosis
#19
Thais Rohde Pavan, Markus Bredemeier, Vanessa Hax, Karina Gatz Capobianco, Rafael da Silva Mendonça Chakr, Ricardo Machado Xavier
The objective of this study is to test the association of the severity of nailfold capillaroscopy (NFC) abnormalities with mortality in systemic sclerosis (SSc). One hundred and seventy SSc patients underwent an extensive evaluation (including high-resolution computed tomography, pulmonary function tests, and Doppler echocardiography) at baseline following a standard protocol. Capillary loss on NFC was evaluated using the avascular score (AS, ranging from 0 to 3), and the mean number of ectasias, megacapillaries, and hemorrhages per finger was also recorded...
October 10, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28993165/motor-sparing-continuous-median-nerve-block-for-hand-surgery-a%C3%A2-pediatric-case
#20
Takeshi Murouchi
Here is described a successful perioperative pain control with continuous median nerve block after flexor tendon repair surgery on 2nd finger of a child. A 9-year-old patient was admitted for reconstruction surgery. The combination of median nerve block and lateral/medial antecubital cutaneous nerve blocks were performed before the surgery to cover all the surgical incision including the 2nd finger, palm, the graft site proximal to the wrist, and Kleinert traction at the nail bed. At the end of the surgery, the infusion catheter was inserted at the distal one-third to spare the muscle strength of flexor digitorum muscles...
September 22, 2017: Asian J Anesthesiol
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