keyword
MENU ▼
Read by QxMD icon Read
search

biologic, rheumatoid, gout, sle

keyword
https://www.readbyqxmd.com/read/25381481/new-treatments-for-inflammatory-rheumatic-disease
#1
REVIEW
Carlo Selmi, Elena Generali, Marco Massarotti, Gerolamo Bianchi, Carlo A Sciré
As our understanding of the pathogenesis of autoimmune diseases is growing, new therapies are being developed to target disease-specific pathways. Since the introduction of etanercept in 1998, several biotechnological agents have been developed, most of them indicated in the treatment of rheumatoid arthritis, but also psoriatic arthritis. Most currently available molecules target TNF-alfa with different strategies (i.e., etanercept, infliximab, adalimumab, golimumab, and certolizumab pegol), IL-6 (tocilizumab), CTLA-4 (abatacept), and B cells (rituximab, belimumab) as they are key mediators in the cascade of inflammation...
December 2014: Immunologic Research
https://www.readbyqxmd.com/read/24589726/fibromyalgia-in-patients-with-other-rheumatic-diseases-prevalence-and-relationship-with-disease-activity
#2
Sema Haliloglu, Ayse Carlioglu, Derya Akdeniz, Yasar Karaaslan, Ali Kosar
Fibromyalgia (FM) is a syndrome characterized by chronic widespread pain and the presence of specific tender points. The prevalence of FM has been estimated at 2-7 % of the general global population. The presence of FM in several rheumatic diseases with a structural pathology has been reported as 11-30 %. The objectives of this study were to determine the prevalence of FM and to evaluate the possible relationship between FM existence and disease activity among rheumatic diseases. The study group included 835 patients--197 rheumatoid arthritis (RA), 67 systemic lupus erythematosus (SLE), 119 ankylosing spondylitis (AS), 238 osteoarthritis (OA), 14 familial Mediterranean fever (FMF), 53 Behçet's disease (BD), 71 gout, 25 Sjögren's syndrome (SS), 20 vasculitis, 29 polymyalgia rheumatica (PMR), and two polymyositis (PM)--with or without FM...
September 2014: Rheumatology International
https://www.readbyqxmd.com/read/24326035/proceedings-of-the-5th-annual-perspectives-in-rheumatic-diseases
#3
Daniel E Furst, Brian Mandell, Leonard H Calabrese, Jennifer C Cather, Daniel J Clauw, Atul Deodhar, Joel M Kremer, E Michael Lewiecki, Maureen McMahon, Christopher T Ritchlin
OBJECTIVES: Update on rheumatic diseases and their intersection with dermatology. RESULTS: This continuing medical education conference included more than 25 presentations and interactive sessions from leading experts in managing rheumatic diseases, comorbid conditions and related dermatologic diseases. Multiple areas were discussed, including: treating newly diagnosed rheumatoid arthritis; comparing Biologics in rheumatoid arthritis; examining changed approaches to treating SLE, psoriasis, psoriatic arthritis, ankylosing spondylitis, gout and vasculitis...
December 2013: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/23996840/doppler-us-in-rheumatic-diseases-with-special-emphasis-on-rheumatoid-arthritis-and-spondyloarthritis
#4
REVIEW
Hüseyin Toprak, Erkan Kılıç, Aslı Serter, Ercan Kocakoç, Salih Özgöçmen
Developments in digital ultrasonography (US) technology and the use of high-frequency broadband transducers have increased the quality of US imaging, particularly of superficial tissues. Thus, US, particularly color US or power Doppler US, in which high-resolution transducers are used, has become an important imaging modality in the assessment of rheumatic diseases. Furthermore, therapeutic interventions and biopsies can be performed under US guidance during the assessment of lesions. In this era of effective treatments, such as biologics, improvements in synovial inflammation in rheumatoid arthritis as well as changes in enthesitis in spondyloarthropathies, including ankylosing spondylitis and psoriatic arthritis, can be monitored effectively using gray-scale and/or power Doppler US...
January 2014: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/19481238/nerve-growth-factor-in-rheumatic-diseases
#5
REVIEW
Matthias F Seidel, Marjeta Herguijuela, Randolf Forkert, Uwe Otten
OBJECTIVES: The nervous system modulates the immune response in many autoimmune syndromes by neurogenic inflammation. One of the pivotal mediators is nerve growth factor (NGF), which is known for its effects on neuronal survival and growth. There is considerable evidence that NGF acts as an important mediator of many immune responses. This article reviews the role of NGF in rheumatic diseases and strategies for potential therapeutic interventions. METHODS: We conducted a database search using Medline and Medpilot...
October 2010: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/17396109/primer-establishing-a-clinical-trial-unit-regulations-and-infrastructure
#6
REVIEW
Roy Fleischmann
The performance of clinical trials can be very rewarding for the practicing or academic clinical rheumatologist. There are at least 50 new compounds - small molecules and biologics - in development for rheumatic diseases such as rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus, ankylosing spondylitis, psoriatic arthritis, scleroderma, gout and fibromyalgia. Clinical trials are important to try to determine the appropriate use of these compounds, as well as to answer questions about their safety...
April 2007: Nature Clinical Practice. Rheumatology
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"