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https://www.readbyqxmd.com/read/28229126/assessing-quality-of-life-in-alzheimer-s-disease-implications-for-clinical%C3%A2-trials
#1
Kristin Kahle-Wrobleski, Wenyu Ye, David Henley, Ann Marie Hake, Eric Siemers, Yun-Fei Chen, Hong Liu-Seifert
INTRODUCTION: Characterization of the quality of life (QOL) in Alzheimer's disease (AD) scale within the context of a clinical trial may inform its applicability in future trials. METHODS: Using data from 1322 patients enrolled in two phase-III studies (EXPEDITION 1 [NCT00905372] and 2 [NCT00904683]) of intravenous solanezumab in outpatients with mild AD dementia, correlations between patient- and caregiver-assessed QOL and between QOL and clinical outcome measures were examined...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28223263/apps-for-people-with-rheumatoid-arthritis-to-monitor-their-disease-activity-a-review-of-apps-for-best-practice-and-quality
#2
Rebecca Grainger, Hermaleigh Townsley, Bonnie White, Tobias Langlotz, William J Taylor
BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory arthritis requiring long-term treatment with regular monitoring by a rheumatologist to achieve good health outcomes. Since people with RA may wish to monitor their own disease activity with a smartphone app, it is important to understand the functions and quality of apps for this purpose. OBJECTIVE: The aim of our study was to assess the features and quality of apps to assist people to monitor their RA disease activity by (1) summarizing the available apps, particularly the instruments used for measurement of RA disease activity; (2) comparing the app features with American College of Rheumatology and European League against Rheumatism (ACR and EULAR) guidelines for monitoring of RA disease activity; and (3) rating app quality with the Mobile App Rating Scale (MARS)...
February 21, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28205056/analyzing-health-related-quality-of-life-data-to-estimate-parameters-for-cost-effectiveness-models-an-example-using-longitudinal-eq-5d-data-from-the-shift-randomized-controlled-trial
#3
Alison Griffiths, Noman Paracha, Andrew Davies, Neil Branscombe, Martin R Cowie, Mark Sculpher
INTRODUCTION: The aim of this article is to discuss methods used to analyze health-related quality of life (HRQoL) data from randomized controlled trials (RCTs) for decision analytic models. The analysis presented in this paper was used to provide HRQoL data for the ivabradine health technology assessment (HTA) submission in chronic heart failure. METHODS: We have used a large, longitudinal EuroQol five-dimension questionnaire (EQ-5D) dataset from the Systolic Heart Failure Treatment with the I f Inhibitor Ivabradine Trial (SHIFT) (clinicaltrials...
February 15, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28185600/health-and-lifestyle-factors-associated-with-sexual-difficulties-in-men-results-from-a-study-of-australian-men-aged-18-to-55%C3%A2-years
#4
Marisa Schlichthorst, Lena A Sanci, Jane S Hocking
BACKGROUND: Sexual difficulties (SD) are common among men of all ages and can have considerable impact on quality of life and indications for future health. SD are associated with mental and physical wellbeing and with relationship satisfaction, yet they are rarely discussed with medical professionals who are often ill equipped to assess and manage them. This paper provides an updated overview on the status of SD in Australian men from 18 to 55 years of age and will form a baseline comparison for future analyses of SD based on Ten to Men data...
October 31, 2016: BMC Public Health
https://www.readbyqxmd.com/read/28185559/psychosocial-job-quality-mental-health-and-subjective-wellbeing-a-cross-sectional-analysis-of-the-baseline-wave-of-the-australian-longitudinal-study-on-male-health
#5
Anthony D LaMontagne, Allison Milner, Lauren Krnjacki, Marisa Schlichthorst, Anne Kavanagh, Kathryn Page, Jane Pirkis
BACKGROUND: Employment status and working conditions are strong determinants of male health, and are therefore an important focus in the Australian Longitudinal Study on Male Health (Ten to Men). In this paper, we describe key work variables included in Ten to Men, and present analyses relating psychosocial job quality to mental health and subjective wellbeing at baseline. METHODS: A national sample of males aged 10 to 55 years residing in private dwellings was drawn using a stratified multi-stage cluster random sample design...
October 31, 2016: BMC Public Health
https://www.readbyqxmd.com/read/28185268/interventions-for-raising-breast-cancer-awareness-in-women
#6
REVIEW
Máirín O'Mahony, Harry Comber, Tony Fitzgerald, Mark A Corrigan, Eileen Fitzgerald, Elizabeth A Grunfeld, Maura G Flynn, Josephine Hegarty
BACKGROUND: Breast cancer continues to be the most commonly diagnosed cancer in women globally. Early detection, diagnosis and treatment of breast cancer are key to better outcomes. Since many women will discover a breast cancer symptom themselves, it is important that they are breast cancer aware i.e. have the knowledge, skills and confidence to detect breast changes and present promptly to a healthcare professional. OBJECTIVES: To assess the effectiveness of interventions for raising breast cancer awareness in women...
February 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28185239/family-impact-of-migraine-development-of-the-impact-of-migraine-on-partners-and-adolescent-children-impac-scale
#7
Richard B Lipton, Dawn C Buse, Aubrey Manack Adams, Sepideh F Varon, Kristina M Fanning, Michael L Reed
OBJECTIVE: To describe the development of the Impact of Migraine on Partners and Adolescent Children (IMPAC) scale. BACKGROUND: Although existing data and clinical experience suggest that the impact of migraine is pervasive and extends beyond the individual with migraine, no validated tools exist for assessing the impact of migraine on the family. METHODS: The Chronic Migraine Epidemiology and Outcomes (CaMEO) Study is a longitudinal study of people with migraine in the United States...
February 10, 2017: Headache
https://www.readbyqxmd.com/read/28182449/the-family-environment-in-early-childhood-has-a-long-term-effect-on-self-esteem-a-longitudinal-study-from-birth-to-age-27-years
#8
Ulrich Orth
A better understanding is needed of the factors that shape the development of individual differences in self-esteem. Using a prospective longitudinal design, this research tested whether the family environment in early childhood predicts self-esteem in later developmental periods. Data came from a nationally representative U.S. sample of 8,711 participants, who reported on their self-esteem biannually from age 8 to 27 years. Moreover, during the participants' first 6 years of life, biannual assessments of their mothers provided information on the quality of the home environment (covering quality of parenting, cognitive stimulation, and physical home environment), quality of parental relationship, presence of father, maternal depression, and poverty status of the family...
February 9, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28177120/impact-of-periodontal-disease-on-quality-of-life-a-systematic-review
#9
REVIEW
M C Ferreira, A C Dias-Pereira, L S Branco-de-Almeida, C C Martins, S M Paiva
The diagnosis of periodontal disease is commonly based on objective evaluations of the patient's medical/dental history as well as clinical and radiographic examinations. However, periodontal disease should also be evaluated subjectively through measures that quantify its impact on oral health-related quality of life. The aim of this study was to evaluate the impact of periodontal disease on quality of life among adolescents, adults and older adults. A systematic search of the literature was performed for scientific articles published up to July 2015 using electronic databases and a manual search...
February 8, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28169577/physical-activity-and-health-related-quality-of-life-in-adults-with-type-2-diabetes-results-from-a-prospective-cohort-study
#10
Danielle M Thiel, Fatima Al Sayah, Jeff Vallance, Steven T Johnson, Jeffrey A Johnson
BACKGROUND: The objective was to investigate the longitudinal relationship between physical activity and health-related quality of life (HRQL) in adults with type 2 diabetes. METHODS: Data were from a prospective cohort of adults with type 2 diabetes. Weekly moderate-vigorous physical activity (MVPA) was reported using the Godin Leisure-Time Physical Activity Questionnaire, and HRQL was reported using the SF-12 and 5-level EQ-5D. Participants were categorized based on current weekly MVPA recommendations...
February 7, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28163319/diet-diversity-growth-and-adiposity-in-healthy-breastfed-infants-fed-homemade-complementary-foods
#11
E Mok, C A Vanstone, S Gallo, P Li, E Constantin, H A Weiler
BACKGROUND/OBJECTIVES: Infant complementary feeding is important for establishing food preferences. Few studies exist on the effects of infant complementary feeding choices (food preparation methods) on dietary intake, growth or adiposity. We examined whether provision of homemade complementary food is associated with the development of dietary diversity, nutrient intakes and quality of infant growth. SUBJECTS/METHODS: Secondary analysis of feeding practices from a randomized trial of vitamin D supplementation in 132 healthy breastfed 1-month old infants from Montréal, Canada...
February 6, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28156655/a-two-group-study-to-evaluate-the-impact-of-an-educational-handbook-in-the-care-of-patients-with-head-and-neck-cancer-hnc
#12
Areej El-Jawahri, Karen Quinn, Lisa Arcikowski, Gina Chan, Elene Viscosi, Carol Doherty, John Ross Clark, Jennifer S Temel, Lori J Wirth
: 228 Background: Patients undergoing chemoradiotherapy for HNC have a significant symptom burden, psychological distress, and educational needs. We evaluated the impact of an educational handbook integrated into oncology care on patient outcomes. METHODS: We conducted a two group, prospective, longitudinal study. Patients enrolled in group 1 received standard care as a control. Then, patients in group 2 received the intervention of a specialized handbook integrated into weekly visits with oncology clinicians during treatment...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156440/patient-reported-outcomes-pros-in-patients-with-human-papilloma-virus-hpv-positive-versus-negative-head-and-neck-cancer-hnc
#13
Areej El-Jawahri, Karen Quinn, Lisa Arcikowski, Gina Chan, Elene Viscosi, Carol Doherty, John Ross Clark, Lori J Wirth, Jennifer S Temel
: 87 Background: HNC caused by HPV has become an epidemic. Treatment for HNC results in a tremendous symptom burden. The impact of HPV-status on quality of life (QOL) and how this effects illness perception and mood has not been described. We sought to explore differences in PROs in patients with HPV + vs. - HNC. METHODS: This is a secondary analysis of data from a prospective, longitudinal intervention study of 60 patients with newly diagnosed HNC undergoing concurrent chemoradiation...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156436/effect-of-edmonton-symptom-assessment-scale-esas-on-symptom-data-collection-in-a-radiation-oncology-department
#14
Puja Venkat, Michael Yu
: 83 Background: ESAS has been used to examine quality of life and symptom burden of patients undergoing cancer treatment. The purpose of this study is to examine attitudes towards ESAS among patients in a Radiation Oncology clinic in conjunction with the perspective of cancer care professionals, to establish ideal implementation of this tool to improve patient care. METHODS: Routine use of ESAS in a single Radiation Oncology Department was initiated in July 2015...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28153990/race-and-sex-differences-in-post-myocardial-infarction-angina-frequency-and-risk-of-1-year-unplanned-rehospitalization
#15
Connie N Hess, Lisa A Kaltenbach, Jacob A Doll, David J Cohen, Eric D Peterson, Tracy Y Wang
BACKGROUND: Race and sex disparities in in-hospital treatment and outcomes of patients with acute myocardial infarction (MI) have been described, but little is known about race and sex differences in post-MI angina and long-term risk of unplanned rehospitalization. We examined race and sex differences in post-MI angina frequency and 1-year unplanned rehospitalization to identify factors associated with unplanned rehospitalization, testing for whether race and sex modify these relationships...
February 7, 2017: Circulation
https://www.readbyqxmd.com/read/28152947/measuring-value-in-bundled-payments-for-head-and-neck-cancer
#16
Tracy E Spinks, Alexis B Guzman, Randal S Weber, Ehab Y Hanna, Amy Clark Hessel, Beth Michelle Beadle, Kate A Hutcheson, James Incalcaterra, Nancy M Wood, Delrose Jones, Thomas W Feeley
: 11 Background: Value, defined as outcomes relative to costs, cannot be improved without rigorous long-term measurement. To assess value within a bundled payment pilot for head and neck cancer, we aim to generate timely, patient-centered outcomes and robust, near-real time financial tracking (Porter and Teisberg, Redefining health care. Creating value-based competition on results; Harvard Business School Press, 2006). METHODS: Clinical and quality experts created an outcome measure set for head and neck cancer, using a three-tiered outcomes hierarchy from Michael Porter of Harvard Business School as a framework...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152712/application-of-a-standard-practice-based-system-to-measure-and-compare-quality-of-cancer-survivorship-care
#17
Katherine Ramsey Gilmore, Patricia Chapman, Paula A Lewis-Patterson, Maria Alma Rodriguez
: 239 Background: Despite the growing committment to improve survivorship care, measuring its quality remains difficult. In 2006, the American Society of Clinical Oncologists (ASCO) launched a practice-based system known as the Quality Oncology Practice Initiative (QOPI) to measure the quality of cancer care. Here, we demonstrate the use of QOPI procedures to compare compliance with survivorship care plans (SCPs) across different disease-specific clinics. METHODS: Measures based on survivorship clinical practice guidelines were abstracted from SCPs issued to survivors scheduled for appointments in site-specific clinics...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152169/albuminuria-in-association-with-cognitive-function-and-dementia-a-systematic-review-and-meta-analysis
#18
Marios K Georgakis, Nikolaos G Dimitriou, Maria A Karalexi, Constantinos Mihas, Efthimia G Nasothimiou, Dimitrios Tousoulis, Georgios Tsivgoulis, Eleni Th Petridou
OBJECTIVES: Cerebral microvascular disease is considered to contribute to cognitive dysfunction. We opted to explore whether albuminuria, a marker of systemic microangiopathy, is associated with cognitive impairment, dementia, and cognitive function. DESIGN: Systematic review; independent reviewers screened 2359 articles, derived through the search strategy, for identification of observational studies quantifying an association of albuminuria with the outcomes of interest, abstracted data on study characteristics and results and evaluated studies on quality using the Newcastle-Ottawa scale...
February 2, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28152108/breast-cancer-survivors-recollection-of-their-quality-of-life-identifying-determinants-of-recall-bias-in-a-longitudinal-population-based-trial
#19
Patricia Lindberg, Petra Netter, Michael Koller, Brunhilde Steinger, Monika Klinkhammer-Schalke
BACKGROUND: The recollections of survivors of breast cancer are an important source of information about the disease for their family, friends, and newly diagnosed patients. So far, little is known about these memories. This study investigated how accurately survivors of breast cancer remember their past quality of life (QoL) during the disease and if this memory is modified by women`s present QoL and negative affect. MATERIAL AND METHODS: The longitudinal population-based study included 133 survivors of breast cancer (response rate 80%)...
2017: PloS One
https://www.readbyqxmd.com/read/28151986/longitudinal-changes-in-health-related-quality-of-life-in-children-with-migrant-backgrounds
#20
Ester Villalonga-Olives, Ichiro Kawachi, Josue Almansa, Nicole von Steinbüchel
BACKGROUND: Little is known about longitudinal changes in the Health Related Quality of Life (HRQoL) among children with migrant backgrounds. METHODS: The sample comprised 350 children with predominantly migrant backgrounds enrolled in 7 kindergartens in Frankfurt and Darmstadt, Germany. At baseline, the participants' mean age was 4.4 years (SD 0.9). Data collection started in May 2009. Two waves of data were collected one year apart (94% response rate). HRQoL was evaluated with the Kiddy-KINDL...
2017: PloS One
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