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longitudinal and data and quality and assessment

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https://www.readbyqxmd.com/read/28916198/treatment-outcome-and-quality-of-life-of-1239-patients-with-advanced-non-small-cell-lung-cancer-final-results-from-the-prospective-german-tlk-cohort-study
#1
Ulla von Verschuer, Roland Schnell, Hans Werner Tessen, Jochen Eggert, Adrian Binninger, Lisa Spring, Martina Jänicke, Norbert Marschner
OBJECTIVES: Real-life data on advanced non-small cell lung cancer (NSCLC) are centrally important to complement the results from clinical trials and to improve the standard of care. We present data on the choice of systemic first- and second-line treatment, number of treatment lines, survival and longitudinal data on health-related quality of life (HRQOL) of patients treated by medical oncologists in Germany. MATERIALS AND METHODS: 1239 patients with advanced NSCLC were recruited at start of first-line therapy into the prospective German clinical cohort study TLK (Tumour Registry Lung Cancer) by 107 sites between February 2010 and December 2013 and followed-up until January 2016...
August 22, 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28915273/longitudinal-co-variations-between-inflammatory-cytokines-lung-function-and-patient-reported-outcomes-in-patients-with-asthma
#2
Karin Lodin, Mats Lekander, Jörgen Syk, Kjell Alving, Predrag Petrovic, Anna Andreasson
BACKGROUND: Asthma is a chronic inflammatory respiratory disorder associated with reduced lung function and poor quality of life. The condition is also associated with poor self-rated health, a major predictor of objective health trajectories. Of biological correlates to self-rated health, evidence suggests a role for inflammatory cytokines and related sickness behaviours. However, this is mainly based on cross-sectional data, and the relation has not been investigated in patients with chronic inflammatory conditions...
2017: PloS One
https://www.readbyqxmd.com/read/28903016/arthroscopic-meniscectomy-for-degenerative-meniscal-tears-reduces-knee-pain-but-is-not-cost-effective-in-a-routine-health-care-setting-a-multi-center-longitudinal-observational-study-using-data-from-the-osteoarthritis-initiative
#3
Jan J Rongen, Tim M Govers, Pieter Buma, Maroeska M Rovers, Gerjon Hannink
OBJECTIVES: It is disputed whether arthroscopic meniscectomy is an (cost-) effective treatment for degenerative meniscus tears in day-to-day clinical practice. The objective of this study was to assess the cost-effectiveness of arthroscopic meniscectomy in subjects with knee osteoarthritis, in routine clinical practice, while taking into account the increased risk for future knee replacement surgery. We compared cost-effectiveness of arthroscopic meniscectomy compared to no surgery. DESIGN: - We used a state transition (Markov) simulation model to evaluate the cost-effectiveness of arthroscopic meniscectomy compared to no surgery in subjects with knee osteoarthritis (age range 45- 79 years)...
September 10, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28902874/psychometric-properties-of-the-brisbane-burn-scar-impact-profile-in-adults-with-burn-scars
#4
Zephanie Tyack, Roy Kimble, Steven McPhail, Anita Plaza, Megan Simons
OBJECTIVE: The aim of the study was to determine the longitudinal validity, reproducibility, responsiveness and interpretability of the adult version of the Brisbane Burn Scar Impact Profile, a patient-report measure of health-related quality of life. METHODS: A prospective longitudinal cohort study of patients with or at risk of burn scarring was conducted at three assessment points (at baseline around the time of wound healing, one to two weeks post-baseline and 1-month post-baseline)...
2017: PloS One
https://www.readbyqxmd.com/read/28892128/nursing-home-use-across-the-spectrum-of-cognitive-decline-merging-mayo-clinic-study-of-aging-with-cms-mds-assessments
#5
Jane A Emerson, Carin Y Smith, Kirsten H Long, Jeanine E Ransom, Rosebud O Roberts, Steven L Hass, Amy M Duhig, Ronald C Petersen, Cynthia L Leibson
BACKGROUND/OBJECTIVES: Objective, complete estimates of nursing home (NH) use across the spectrum of cognitive decline are needed to help predict future care needs and inform economic models constructed to assess interventions to reduce care needs. DESIGN: Retrospective longitudinal study. SETTING: Olmsted County, MN. PARTICIPANTS: Mayo Clinic Study of Aging participants assessed as cognitively normal (CN), mild cognitive impairment (MCI), previously unrecognized dementia, or prevalent dementia (age = 70-89 years; N = 3,545)...
September 11, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28888358/prediction-of-self-stigma-in-early-psychosis-3-year-follow-up-of-the-randomized-controlled-trial-on-extended-early-intervention
#6
Ryan Wui Hang Ho, Wing Chung Chang, Vivian Wing Yan Kwong, Emily Sin Kei Lau, Gloria Hoi Kei Chan, Olivia Tsz Ting Jim, Christy Lai Ming Hui, Sherry Kit Wa Chan, Edwin Ho Ming Lee, Eric Yu Hai Chen
BACKGROUND: Self-stigma represents a major barrier to recovery in people with psychotic disorders but is understudied in early illness stage. Longitudinal investigation of prediction for self-stigma is scarce and none is conducted in early psychosis. We aimed to prospectively examine baseline predictors of self-stigma in early psychosis patients in the context of a 3-year follow-up of a randomized-controlled trial (RCT) comparing 1-year extension of early intervention (EI) with step-down psychiatric care for first-episode psychosis (FEP)...
September 6, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28886146/association-between-health-literacy-and-patient-experience-of-primary-care-attributes-a-cross-sectional-study-in-japan
#7
Takuya Aoki, Machiko Inoue
Primary care is regarded as a setting that potentially mitigate patient health literacy (HL) related inequalities. However, there is a lack of evidence about influence of patient HL on the patients' perception of quality of primary care. We aimed to examine the association between HL and patient experience of primary care attributes. We conducted a cross-sectional survey, and sent questionnaires to adult residents who were randomly selected from a basic resident register in Yugawara Town, Kanagawa, Japan. We assessed HL using a 14-item Health Literacy Scale (HLS-14) and patient experience of primary care attributes using a Japanese version of Primary Care Assessment Tool (JPCAT), which comprises six domains: first contact, longitudinality, coordination, comprehensiveness (services available), comprehensiveness (services provided), and community orientation...
2017: PloS One
https://www.readbyqxmd.com/read/28886018/minimal-important-change-and-other-measurement-properties-of-the-oxford-elbow-score-and-the-quick-disabilities-of-the-arm-shoulder-and-hand-in-patients-with-a-simple-elbow-dislocation-validation-study-alongside-the-multicenter-funcsie-trial
#8
Gijs I T Iordens, Dennis Den Hartog, Wim E Tuinebreijer, Denise Eygendaal, Niels W L Schep, Michael H J Verhofstad, Esther M M Van Lieshout
STUDY DESIGN: Validation study using data from a multicenter, randomized, clinical trial (RCT). OBJECTIVES: To evaluate the reliability, validity, responsiveness, and minimal important change (MIC) of the Dutch version of the Oxford Elbow Score (OES) and the Quick Disabilities of the Arm, Shoulder, and Hand (Quick-DASH) in patients with a simple elbow dislocation. BACKGROUND: Patient-reported outcome measures are increasingly important for assessing outcome following elbow injuries, both in daily practice and in clinical research...
2017: PloS One
https://www.readbyqxmd.com/read/28882810/study-of-methods-for-assessing-research-topic-elicitation-and-prioritization-smarter-study-protocol-to-compare-qualitative-research-methods-and-advance-patient-engagement-in-research
#9
Danielle C Lavallee, Bryan Comstock, Mary R Scott, Andrew L Avins, David R Nerenz, Todd C Edwards, Donald L Patrick, Sarah O Lawrence, Zoya Bauer, Anjali R Truitt, Jeffrey G Jarvik
BACKGROUND: Involving patients as partners in research is a defining characteristic of patient-centered outcomes research (PCOR). While patients' experiential knowledge of a health condition or treatment may yield research priorities not reflected by researchers and policy makers, the methods for identifying and effectively collaborating with patients are still evolving. Patient registries and crowdsourcing may offer ease of access and convenience to both researchers and patients. Surveys and focus groups, including online modalities, have been described for prioritizing research topics...
September 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28880843/a-novel-dual-gating-approach-using-joint-inertial-sensors-implications-for-cardiac-pet-imaging
#10
Mojtaba Jafari Tadi, Jarmo Teuho, Eero Lennart Lehtonen, Antti Saraste, Mikko Pänkäälä, Tero Koivisto, Mika Teras
Positron emission tomography (PET) is a non-invasive imaging technique which may be considered as the state of art for the examination of cardiac inflammation due to atherosclerosis. A fundamental limitation of PET is that cardiac and respiratory motions reduce the quality of the achieved images. Current approaches for motion compensation involve gating the PET data based on the timing of quiescent periods of cardiac and respiratory cycles. In this study, we present a novel gating method called microelectromechanical (MEMS) dual gating which relies on joint non-electrical sensors, i...
September 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28869435/in-vivo-effects-of-limb-movement-on-nerve-stretch-strain-and-tension-a-systematic-review
#11
Tibor Szikszay, Toby Hall, Harry von Piekartz
BACKROUND: The mechanical behavior of the peripheral nervous system under elongation and tension has not been adequately established in vivo. OBJECTIVE: The purpose of this review is to investigate the mechanical behavior of the peripheral nervous system in vivo. METHODS: In vivo studies which evaluated the effects of limb movement and neurodynamic tests on peripheral nerve biomechanics were systematically searched in PubMed (Medline), the Cochrane Database, CINAHL, PEDro, Embase and Web of Science...
August 25, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28865473/development-and-preliminary-validation-of-a-post-fistula-repair-reintegration-instrument-among-ugandan-women
#12
Alison El Ayadi, Hadija Nalubwama, Justus Barageine, Torsten B Neilands, Susan Obore, Josaphat Byamugisha, Othman Kakaire, Haruna Mwanje, Abner Korn, Felicia Lester, Suellen Miller
BACKGROUND: Obstetric fistula is a debilitating and traumatic birth injury affecting 2-3 million women globally, mostly in sub-Saharan Africa and Asia. Affected women suffer physically, psychologically and socioeconomically. International efforts have increased access to surgical treatment, yet attention to a holistic outcome of post-surgical rehabilitation is nascent. We sought to develop and pilot test a measurement instrument to assess post-surgical family and community reintegration...
September 2, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28864128/residential-green-space-quantity-and-quality-and-child-well-being-a-longitudinal-study
#13
Xiaoqi Feng, Thomas Astell-Burt
INTRODUCTION: There are few studies on the potential benefits of green space quantity and quality for child well-being. The authors hypothesized that more and better quality residential green space would be favorable for well-being and that these associations could be subject to effect modification across childhood. METHOD: Multilevel linear regression adjusted for demographic and socioeconomic confounders was used to track change in well-being (Strengths and Difficulties Questionnaire Total Difficulties Score and "internalizing" and "externalizing" subscales) across five separate occasions among a cohort of 4,968 Australian children aged 4-5 years beginning in 2004...
August 28, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28859696/a-systematic-review-of-evidence-for-fitness-to-drive-among-people-with-the-mental-health-conditions-of-schizophrenia-stress-anxiety-disorder-depression-personality-disorder-and-obsessive-compulsive-disorder
#14
Carolyn A Unsworth, Anne M Baker, Man H So, Priscilla Harries, Desmond O'Neill
BACKGROUND: Limited evidence exists regarding fitness-to-drive for people with the mental health conditions of schizophrenia, stress/anxiety disorder, depression, personality disorder and obsessive compulsive disorder (herein simply referred to as 'mental health conditions'). The aim of this paper was to systematically search and classify all published studies regarding driving for this population, and then critically appraise papers addressing assessment of fitness-to-drive where the focus was not on the impact of medication on driving...
August 31, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28857972/are-you-making-an-impact-evaluating-the-population-health-impact-of-community-benefit-programs
#15
Catherine M Rains, Greta Todd, Nicole Kozma, Melody S Goodman
CONTEXT: The Patient Protection and Affordable Care Act includes a change to the IRS 990 Schedule H, requiring nonprofit hospitals to submit a community health needs assessment every 3 years. Such health care entities are challenged to evaluate the effectiveness of community benefit programs addressing the health needs identified. OBJECTIVE: In an effort to determine the population health impact of community benefit programs in 1 hospital outreach department, researchers and staff conducted an impact evaluation to develop priority areas and overarching goals along with program- and department-level objectives...
August 29, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28851330/childhood-obesity-and-adult-cardiovascular-disease-risk-factors-a-systematic-review-with-meta-analysis
#16
Amna Umer, George A Kelley, Lesley E Cottrell, Peter Giacobbi, Kim E Innes, Christa L Lilly
BACKGROUND: Overweight and obesity is a major public health concern that includes associations with the development of cardiovascular disease (CVD) risk factors during childhood and adolescence as well as premature mortality in adults. Despite the high prevalence of childhood and adolescent obesity as well as adult CVD, individual studies as well as previous systematic reviews examining the relationship between childhood obesity and adult CVD have yielded conflicting results. The purpose of this study was to use the aggregate data meta-analytic approach to address this gap...
August 29, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28846050/a-hierarchical-rater-model-for-longitudinal-data
#17
Jodi M Casabianca, Brian W Junker, Ricardo Nieto, Mark A Bond
Research studies in psychology and education often seek to detect changes or growth in an outcome over a duration of time. This research provides a solution to those interested in estimating latent traits from psychological measures that rely on human raters. Rater effects potentially degrade the quality of scores in constructed response and performance assessments. We develop an extension of the hierarchical rater model (HRM), which yields estimates of latent traits that have been corrected for individual rater bias and variability, for ratings that come from longitudinal designs...
August 28, 2017: Multivariate Behavioral Research
https://www.readbyqxmd.com/read/28845694/self-regulation-of-weight-after-sleeve-gastrectomy
#18
Teresa Madeira, Isabel do Carmo, Henrique Bicha Castelo, Osvaldo Santos
Bariatric surgery is recognized as the most effective method for achieving relevant weight loss in subjects with severe obesity. However, there is insufficient knowledge about weight self-regulation and quality of motivation in these patients. The main goal of this study was to characterize the association between the percentage of excess weight loss (%EWL) and the motivation to manage weight, at least 1 year after sleeve gastrectomy (SG). This is an observational longitudinal retrospective study. All patients corresponding to predefined inclusion criteria who underwent SG from January 2008 to July 2010 at a main general hospital were invited...
August 1, 2017: Behavior Modification
https://www.readbyqxmd.com/read/28845345/the-deployment-life-study-longitudinal-analysis-of-military-families-across-the-deployment-cycle
#19
Sarah O Meadows, Terri Tanielian, Benjamin Karney, Terry Schell, Beth Ann Griffin, Lisa H Jaycox, Esther M Friedman, Thomas E Trail, Robin Beckman, Rajeev Ramchand, Natalie Hengstebeck, Wendy M Troxel, Lynsay Ayer, Christine Anne Vaughan
In 2009, RAND launched the Deployment Life Study, a longitudinal study of military families across a deployment cycle in order to assess family readiness. Family readiness refers to the state of being prepared to effectively navigate the challenges of daily living experienced in the unique context of military service. The study surveyed families at frequent intervals throughout a complete deployment cycle---before a service member deploys (sometimes months before), during the actual deployment, and after the service member returns (possibly a year or more after she or he redeployed)...
January 2017: Rand Health Quarterly
https://www.readbyqxmd.com/read/28838900/a-patient-cohort-on-long-term-sequelae-of-sepsis-survivors-study-protocol-of-the-mid-german-sepsis-cohort
#20
André Scherag, Christiane S Hartog, Carolin Fleischmann, Dominique Ouart, Franziska Hoffmann, Christian König, Miriam Kesselmeier, Sandra Fiedler, Monique Philipp, Anke Braune, Cornelia Eichhorn, Christin Gampe, Heike Romeike, Konrad Reinhart
INTRODUCTION: An increasing number of patients survive sepsis; however, we lack valid data on the long-term impact on morbidity from prospective observational studies. Therefore, we designed an observational cohort to quantify mid-term and long-term functional disabilities after intensive care unit (ICU)-treated sepsis. Ultimately, findings for the Mid-German Sepsis Cohort (MSC) will serve as basis for the implementation of follow-up structures for patients with sepsis and help to increase quality of care for sepsis survivors...
August 23, 2017: BMJ Open
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