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https://www.readbyqxmd.com/read/28648124/knowledge-based-iterative-model-reconstruction-in-coronary-computed-tomography-angiography-comparison-with-hybrid-iterative-reconstruction-and-filtered-back-projection
#1
Min Jae Cha, Jae Seung Seo, Dong Soo Yoo, Semin Chong
Background Knowledge-based iterative model reconstruction (IMR) is known to allow radiation dose reduction while preserving image quality. Purpose To investigate the effect of IMR on coronary computed tomography angiography (CCTA) by comparing it with filtered back projection (FBP) and hybrid iterative reconstruction (HIR). Material and Methods Forty-five patients (group A) who underwent CCTA with prospective electrocardiogram (ECG) triggering at 80 kVp were included. All images were reconstructed using three algorithms: FBP, HIR, and IMR...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28647774/automatic-identification-of-coronary-tree-anatomy-in-coronary-computed-tomography-angiography
#2
Qing Cao, Alexander Broersen, Michiel A de Graaf, Pieter H Kitslaar, Guanyu Yang, Arthur J Scholte, Boudewijn P F Lelieveldt, Johan H C Reiber, Jouke Dijkstra
An automatic coronary artery tree labeling algorithm is described to identify the anatomical segments of the extracted centerlines from coronary computed tomography angiography (CCTA) images. This method will facilitate the automatic lesion reporting and risk stratification of cardiovascular disease. Three-dimensional (3D) models for both right dominant (RD) and left dominant (LD) coronary circulations were built. All labels in the model were matched with their possible candidates in the extracted tree to find the optimal labeling result...
June 24, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28637960/pacemaker-induced-metallic-artifacts-in-coronary-computed-tomography-angiography-clinical-feasibility-of-single-energy-metal-artifact-reduction-technique
#3
Tomoya Takayanagi, Takehiro Arai, Makoto Amanuma, Tomonari Sano, Masato Ichiba, Kazumasa Ishizaka, Takako Sekine, Hideyuki Matsutani, Hitomi Morita, Shinichi Takase
BACKGROUND: Coronary computed tomography angiography (CCTA) in patients with pacemaker suffers from metallic lead-induced artifacts, which often interfere with accurate assessment of coronary luminal stenosis. The purpose of this study was to assess a frequency of the lead-induced artifacts and artifact-suppression effect by the single energy metal artifact reduction (SEMAR) technique. METHODS: Forty-one patients with a dual-chamber pacemaker were evaluated using a 320 multi-detector row CT (MDCT)...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28636511/feasibility-of-low-dose-coronary-computed-tomographic-angiography-used-in-atrial-fibrillation-patients
#4
Chenglin Zhao, Mengxi Jiang, Jianxin Liu, Li Gao, Xiaoying Wang
OBJECTIVE: The diagnosis of coronary artery disease (CAD) in atrial fibrillation (AF) patients using coronary computed tomography angiography (CCTA) requires a large exposure dosage or repeated examinations. This study evaluates the feasibility of using low-dose CCTA in the double prospectively ECG-triggered high-pitch spiral acquisition mode (Double Flash Spiral mode). METHODS: Twenty-eight AF patients with suspected CAD were recruited. Double Flash Spiral mode (tube voltage 100 kVp) and iterative reconstruction was used for CCTA examination...
March 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28620616/the-impact-of-combining-a-low-tube-voltage-acquisition-with-iterative-reconstruction-on-total-iodine-dose-in-coronary-ct-angiography
#5
Toon Van Cauteren, Gert Van Gompel, Kaoru Tanaka, Douwe E Verdries, Dries Belsack, Koenraad H Nieboer, Inneke Willekens, Paul Evans, Sven Macholl, Guy Verfaillie, Steven Droogmans, Johan de Mey, Nico Buls
OBJECTIVES: To assess the impact of combining low-tube voltage acquisition with iterative reconstruction (IR) techniques on the iodine dose in coronary CTA. METHODS: Three minipigs underwent CCTA to compare a standard of care protocol with two alternative study protocols combining low-tube voltage and low iodine dose with IR. Image quality was evaluated objectively by the CT value, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) in the main coronary arteries and aorta and subjectively by expert reading...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28616535/effect-of-intravenous-infusion-of-iodinated-contrast-media-on-the-coronary-blood-flow-in-dogs
#6
Thura T Abd, Asim I Shafique, Hayder S Yasir, Jung-Hee Seo, Richard T George, Rajat Mittal, Albert C Lardo
BACKGROUND: Coronary computed tomography angiography (CCTA) is obtained using peripheral intravenous iodinated contrast agents (ICA) injection. There is continuing attempts to derive coronary physiological information like coronary blood flow (CBF) and/or fractional flow reserve from CCTA images. However, no data is available regarding the effect of peripheral intravenous injection of ICA on CBF. METHODS: A series of 4 experiments was performed using healthy mongrel dogs...
September 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28613933/quantification-of-radiation-dose-reduction-by-reducing-z-axis-coverage-in-320-detector-coronary-ct-angiography
#7
D J Murphy, A Keraliya, N Himes, A Aghayev, R Blankstein, M L Steigner
OBJECTIVES: To quantify the radiation dose reduction achievable by minimizing z-axis coverage in 320-detector coronary computed tomography angiography (CCTA). METHODS: We retrospectively reviewed 130 CCTAs performed on 320-detector CT that offers up to 16cm z-axis coverage (adjustable in 2cm increments), allowing complete coverage of the heart in a single gantry rotation. For each CT we obtained the radiation dose (CTDIvol and DLP), measured the z-axis field of view and measured the craniocaudal cardiac size (distance from the left main coronary artery to the cardiac apex)...
June 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28613405/an-association-between-volumes-of-the-cardiac-chambers-and-troponin-levels-in-individuals-submitted-to-cardiac-coronary-computed-tomography
#8
Zach Rozenbaum, Yaron Arbel, Yoav Granot, Dotan Cohen, Haim Shmilovich, Tomer Ziv-Baran, Ehud Chorin, Ofer Havakuk, Merav Cohen, Shlomo Berliner, Yan Topilsky, Galit Aviram
BACKGROUND: Previous echocardiographic studies have revealed an association between enlarged cardiac chamber volumes and elevated troponin concentrations. An automatic 4-chamber volumetric analysis tool was adopted to investigate this association in patients who underwent cardiac-gated computed tomography angiography (CCTA). HYPOTHESIS: We hypothesized that troponin concentration within the normal range correlates with cardiac chambers' volumes. METHODS: Serum troponin was obtained from 157 ambulatory patients before undergoing CCTA for nonacute coronary artery evaluation...
June 14, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28600860/estimating-the-accuracy-of-a-reduced-order-model-for-the-calculation-of-fractional-flow-reserve-ffr
#9
Etienne Boileau, Sanjay Pant, Carl Roobottom, Igor Sazonov, Jingjing Deng, Xianghua Xie, Perumal Nithiarasu
Image-based non-invasive fractional flow reserve (FFR) is an emergent approach to determine the functional relevance of coronary stenoses. The present work aimed to determine the feasibility of using a method based on coronary computed tomography angiography (CCTA) and reduced-order models (0D-1D) for the evaluation of coronary stenoses. The reduced-order methodology (cFFRro ) was kept as simple as possible and did not include pressure drop or stenosis models. The geometry definition was incorporated into the physical model used to solve coronary flow and pressure...
June 9, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28600674/-value-of-cardiac-ct-in-the-diagnostic-work-up-of-coronary-artery-disease-update-2017
#10
M Meyer, T Henzler
The quantification of coronary calcifications using noncontrast-enhanced computed tomography (CT) as well as coronary CT angiography (cCTA) have rapidly evolved in the recent years. Nowadays, both techniques are increasingly clinically accepted regarding risk stratification and accurate exclusion of significant coronary artery disease (CAD). The higher acceptance of cCTA is mainly based on the higher robustness, lower radiation exposure through continuous technical innovations as well as by the growing scientific evidence...
June 9, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28597738/improved-diagnostic-accuracy-when-combining-computed-tomography-angiography-and-corrected-coronary-opacification-in-patients-with-coronary-stents
#11
Taylor F Dowsley, Leonid Chepelev, Brian McArdle, Mohammed Alam, Girish Dwivedi, Benjamin J W Chow
Background The accuracy of coronary computed tomography angiography (CCTA) is sub-optimal in patients with coronary stents. Methods that can increase its diagnostic accuracy are desirable. Objective A proof-of-concept study was undertaken to determine if corrected coronary opacification (CCO) differences can improve the accuracy of CCTA in stented coronary arteries. Methods PCI patients who underwent both CCTA and invasive coronary angiography (ICA) within 3 months were analyzed. Coronary luminal attenuation values (normalized to the aorta) were measured proximally and distally to coronary stents...
February 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28595860/diagnostic-performance-of-a-novel-method-for-fractional-flow-reserve-computed-from-noninvasive-computed-tomography-angiography-novel-flow-study
#12
Ju-Hyun Chung, Kyung Eun Lee, Chang-Wook Nam, Joon-Hyung Doh, Hyung Il Kim, Soon-Sung Kwon, Eun Bo Shim, Eun-Seok Shin
Coronary computed tomography angiography (CCTA)-derived fractional flow reserve from computed tomography (CT-FFR) may provide better diagnostic performance over CCTA alone, but the complexity of its method limits the use in clinical environment. The aim of the present study is to validate a newly developed vessel-length based computational fluid dynamics scheme for the computation of FFR based on CCTA data, compare them with invasively measured FFR, and evaluate its diagnostic performance with that of CCTA...
May 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28592383/long-term-outcome-prediction-by-functional-parameters-derived-from-coronary-computed-tomography-angiography
#13
Dominik C Benz, Fran Mikulicic, Christoph Gräni, Dominic Moret, Mathias Possner, Olivier F Clerc, Annina A Studer Bruengger, Oliver Gaemperli, Ronny R Buechel, Aju P Pazhenkottil, Philipp A Kaufmann
BACKGROUND: Estimation of hemodynamic relevance of a coronary stenosis from coronary computed angiography (CCTA) has raised substantial interest. Recently, the corrected coronary opacification (CCO) decrease and the transluminal attenuation gradient (TAG) have been suggested as faster alternatives to the FFRCT. The aim of the study was to evaluate whether the diagnostic accuracy of CCO decrease and TAG translates into an added prognostic value in patients evaluated for coronary artery disease (CAD)...
May 24, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28591861/diagnostic-reference-levels-in-cardiac-computed-tomography-angiography-a-systematic-review
#14
Ali B Alhailiy, Patrick C Brennan, Mark F McEntee, Peter L Kench, Elaine A Ryan
Cardiac computed tomography angiography (CCTA) is a commonly used diagnostic tool for cardiovascular disease. Despite constant improvements to imaging technologies, the radiation dose to patients from CCTA remains a concern when using this procedure. There remains a need for optimisation of CCTA procedures and accurate dose monitoring to reduce the potential risk of cancer. Establishing diagnostic reference levels (DRLs) allows for the assessment of radiation dose variations, enabling strategies aimed at standardising doses across radiological centres...
June 7, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28584585/an-audit-on-the-appropriateness-of-coronary-computed-tomography-angiography-referrals-in-a-tertiary-cardiac-center
#15
Ahmed Ali Alderazi, Mary Lynch
BACKGROUND: In response to growing concerns regarding the overuse of coronary computed tomography angiography (CCTA) in the clinical setting, multiple societies, including the American College of Cardiology Foundation, have jointly published revised criteria regarding the appropriate use of this imaging modality. However, previous research indicates significant discrepancies in the rate of adherence to these guidelines. AIM: To assess the appropriateness of CCTA referrals in a tertiary cardiac center in Bahrain...
January 2017: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/28583653/prospectively-ecg-triggered-high-pitch-coronary-ct-angiography-at-70-kvp-with-30ml-contrast-agent-an-intraindividual-comparison-with-sequential-scanning-at-120-kvp-with-60ml-contrast-agent
#16
Wei Wang, Yan E Zhao, Li Qi, Xie Li, Chang Sheng Zhou, Long Jiang Zhang, Guang Ming Lu
PURPOSE: To investigate image quality, radiation dose, and diagnostic efficiency of prospectively ECG-triggered high-pitch coronary CT angiography (CCTA) at 70 kVp with 30mL contrast agent intra-individually compared with routine CCTA protocol. MATERIALS AND METHODS: One hundred and thirty eight patients with suspected coronary artery disease, body mass index (BMI)≤25kg/m(2) and heart rate (HR)≤70 beats per minute (bpm) underwent prospectively ECG-triggered high-pitch CCTA at 70 kVp and 30mL contrast agent (protocol A) and prospectively ECG-triggered sequential scanning at 120 kVp and 60mL contrast medium (protocol B)...
May 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28571561/high-sensitivity-troponin-i-and-t-reflect-the-presence-of-obstructive-and-multi-vessel-coronary-artery-disease-being-assessed-by-coronary-computed-tomography-angiography
#17
Nadine Reckord, Michèle Natale, Agnibh Mukherji, Jonas Rusnak, Uzair Ansari, Thomas Henzler, Ursula Hoffmann, Martin Borggrefe, Kambis Mashayekhi, Thomas Bertsch, Ibrahim Akin
BACKGROUND: This study evaluates the association between high sensitivity troponin I (hsTnI) and T (hsTnT) in patients with suspected coronary artery disease (CAD) undergoing coronary computed tomography angiography (CCTA). METHODS: Patients undergoing CCTA during routine clinical care were prospectively enrolled. CCTA was indicated by a low to intermediate pre-test probability for CAD during routine clinical care. Within 24 hours before or after CCTA, blood samples were taken to measure cardiac biomarkers hsTnI, hsTnT and NT-proNBP...
May 31, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28567092/additive-role-of-coronary-magnetic-resonance-angiography-for-the-evaluation-of-coronary-artery-disease
#18
Min Jeong Kim, Yeonyee E Yoon, Jin Joo Park, Yeo Koon Kim, Eun Ju Chun, Sang Il Choi, Goo-Young Cho
Coronary magnetic resonance angiography (CMRA) allows a noninvasive assessment of the coronary anatomy without exposing the patients to radiation. It is also superior to coronary computed tomography angiography (CCTA) for the evaluation of luminal narrowing in heavily calcified coronary segments. We report a case with triple-vessel disease, but it could not be accurately assessed by CCTA because of calcification and lack of a significant perfusion defect or myocardial scarring on cardiac magnetic resonance imaging (MRI)...
May 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/28550587/epicardial-adipose-tissue-is-associated-with-high-risk-plaque-feature-progression-in-non-culprit-lesions
#19
Yahang Tan, Jia Zhou, Ying Zhou, Xiaobo Yang, Jing Wang, Yundai Chen
Several studies have suggested a link between epicardial adipose tissue (EAT) volume and high-risk plaques (HRPs); however, little is known about the association between EAT volume and HRP progression in non-culprit lesions (NCLs). Therefore, we evaluated whether EAT can independently predict HRP characteristic progression in NCLs by coronary computed tomography angiography (CCTA). In this single-centre trial, we analysed 131 consecutive patients (median age 61 years, male 72.52%) undergoing CCTA with percutaneous coronary intervention (PCI) for culprit lesions...
May 26, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28549614/validation-and-comparison-of-four-models-to-calculate-pretest-probability-of-obstructive-coronary-artery-disease-in-a-chinese-population-a-coronary-computed-tomographic-angiography-study
#20
Jia Zhou, Yujie Liu, Lingyu Huang, Yahang Tan, Xingchen Li, Hong Zhang, Yanhe Ma, Ying Zhang
OBJECTIVE: We sought to compare the performance of the updated Diamond-Forrester method (UDFM), Duke clinical score (DCS), Genders clinical model (GCM) and Genders extended model (GEM) in a Chinese population referred to coronary computed tomography angiography (coronary CTA). BACKGROUND: The reliability of existing models to calculate the pretest proability (PTP) of obstructive coronary artery disease (CAD) have not been fully investigated, especially in a Chinese population...
July 2017: Journal of Cardiovascular Computed Tomography
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