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https://www.readbyqxmd.com/read/28205072/negative-predictive-value-of-stress-myocardial-perfusion-imaging-and-coronary-computed-tomography-angiography-a-meta-analysis
#1
Roberta Green, Valeria Cantoni, Mario Petretta, Wanda Acampa, Mariarosaria Panico, Pietro Buongiorno, Giorgio Punzo, Marco Salvatore, Alberto Cuocolo
BACKGROUND: Comparing the prognostic value of a negative finding by stress single-photon emission computed tomography myocardial perfusion imaging (MPI) and coronary computed tomography angiography (CCTA) may be useful to evaluate how better identify low-risk patients. We performed a meta-analysis to compare the long-term negative predictive value (NPV) of normal stress MPI and normal CCTA in subjects with suspected coronary artery disease (CAD). METHODS AND RESULTS: Studies published between January 2000 and November 2016 were identified by database search...
February 15, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28199464/identification-of-patients-with-stable-chest-pain-deriving-minimal-value-from-noninvasive-testing-the-promise-minimal-risk-tool-a-secondary-analysis-of-a-randomized-clinical-trial
#2
Christopher B Fordyce, Pamela S Douglas, Rhonda S Roberts, Udo Hoffmann, Hussein R Al-Khalidi, Manesh R Patel, Christopher B Granger, John Kostis, Daniel B Mark, Kerry L Lee, James E Udelson
Importance: Guidelines recommend noninvasive testing for patients with stable chest pain, although many subsequently have normal test results and no adverse clinical events. Objective: To describe a risk tool developed to use only pretest clinical data to identify patients with chest pain with normal coronary arteries and no clinical events during follow-up (minimal-risk cohort). Design, Setting, and Participants: This secondary analysis of a randomized, pragmatic comparative effectiveness trial (Prospective Multicenter Imaging Study for Evaluation of Chest Pain [PROMISE]) includes stable, symptomatic outpatients without known coronary artery disease referred for noninvasive testing at 193 sites in North America...
February 15, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28181032/comprehensive-evaluation-of-chemiluminescent-immunoassays-for-the-laboratory-diagnosis-of-clostridium-difficile-infection
#3
A Makristathis, I Zeller, D Mitteregger, M Kundi, A M Hirschl
For the microbiological diagnosis of a Clostridium (C.) difficile infection (CDI), a two-test algorithm consisting of a C. difficile glutamate dehydrogenase (GDH)-immunoassay followed by a toxin-immunoassay in positive cases is widely used. In this study, two chemiluminescent immunoassays (CLIAs), one for GDH and the other for the toxins A and B, have been evaluated systematically using appropriate reference methods. Three-hundred diarrhoeal stool specimens submitted for CDI diagnosis were analysed by the LIAISON CLIAs (DiaSorin)...
February 8, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28177655/iterative-image-reconstruction-improves-the-accuracy-of-automated-plaque-burden-assessment-in-coronary-ct-angiography-a-comparison-with-intravascular-ultrasound
#4
Stefan B Puchner, Maros Ferencik, Akiko Maehara, Paul Stolzmann, Shixin Ma, Synho Do, Hans-Ulrich Kauczor, Gary S Mintz, Udo Hoffmann, Christopher L Schlett
OBJECTIVE: The purpose of this study was to determine whether use of iterative image reconstruction algorithms improves the accuracy of coronary CT angiography (CCTA) compared with intravascular ultrasound (IVUS) in semiautomated plaque burden assessment. MATERIALS AND METHODS: CCTA and IVUS images of seven coronary arteries were acquired ex vivo. CT images were reconstructed with filtered back projection (FBP) and adaptive statistical (ASIR) and model-based (MBIR) iterative reconstruction algorithms...
February 8, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28177653/prognostic-value-of-stress-dynamic-myocardial-perfusion-ct-in-a-multicenter-population-with-known-or-suspected-coronary-artery-disease
#5
Felix G Meinel, Francesca Pugliese, U Joseph Schoepf, Ullrich Ebersberger, Julian L Wichmann, Gladys G Lo, Yeon Hyeon Choe, Yining Wang, Sabrina Segreto, Fabian Bamberg, Carlo N De Cecco
OBJECTIVE: The purpose of this study was to determine the prognostic value of myocardial perfusion CT for major adverse cardiac events (MACE). MATERIALS AND METHODS: Data from six centers in Asia, Europe, and North America on 144 patients with known or suspected coronary artery disease who had undergone coronary CT angiography (CCTA) and dynamic myocardial perfusion CT with a dual-source CT system were analyzed. CCTA studies were acquired at rest. Dynamic myocardial perfusion CT was performed under vasodilator stress...
February 8, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28168977/diffuse-coronary-artery-disease-among-other-atherosclerotic-plaque-characteristics-by-coronary-computed-tomography-angiography-for-predicting-coronary-vessel-specific-ischemia-by-fractional-flow-reserve
#6
Asim Rizvi, Bríain Ó Hartaigh, Ibrahim Danad, Donghee Han, Ji Hyun Lee, Heidi Gransar, Jackie Szymonifka, Fay Y Lin, James K Min
BACKGROUND AND AIMS: Coronary computed tomography angiography (CCTA) permits effective identification of diffuse CAD and atherosclerotic plaque characteristics (APCs). We sought to examine the usefulness of diffuse CAD beyond luminal narrowing and APCs by CCTA to detect vessel-specific ischemia. METHODS: 407 vessels (n = 252 patients) from the DeFACTO diagnostic accuracy study were retrospectively analyzed for percent plaque diffuseness (PD). Percent plaque diffuseness (PD) was obtained on per-vessel level by summation of all contiguous lesion lengths and divided by total vessel length, and was logarithmically transformed (log percent PD)...
January 16, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28164120/coronary-computed-tomography-angiography-in-combination-with-coronary-artery-calcium-scoring-for-the-preoperative-cardiac-evaluation-of-liver-transplant-recipients
#7
REVIEW
Jae Moon Choi, Yu-Gyeong Kong, Joon-Won Kang, Young-Kug Kim
Liver transplantation is the best treatment option for early-stage hepatocellular carcinoma, liver cirrhosis, fulminant liver failure, and end-stage liver diseases. Even though advances in surgical techniques and perioperative care have improved postoperative outcomes, perioperative cardiovascular complications are a leading cause of postoperative morbidity and mortality following liver transplantation. Ischemic coronary artery disease (CAD) and cardiomyopathy are the most common cardiovascular diseases and could be negative predictors of postoperative outcomes in liver transplant recipients...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28155686/hemodynamic-analysis-of-sequential-graft-from-right-coronary-system-to-left-coronary-system
#8
Wenxin Wang, Boyan Mao, Haoran Wang, Xueying Geng, Xi Zhao, Huixia Zhang, Jinsheng Xie, Zhou Zhao, Bo Lian, Youjun Liu
BACKGROUND: Sequential and single grafting are two surgical procedures of coronary artery bypass grafting. However, it remains unclear if the sequential graft can be used between the right and left coronary artery system. The purpose of this paper is to clarify the possibility of right coronary artery system anastomosis to left coronary system. METHODS: A patient-specific 3D model was first reconstructed based on coronary computed tomography angiography (CCTA) images...
December 28, 2016: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28150280/galectin-3-is-associated-with-coronary-plaque-burden-and-obstructive-sleep-apnea-syndrome-severity
#9
Hamdi Pusuroglu, Umut Somuncu, Ismail Bolat, Ozgur Akgul, Vesile Ornek, Hayriye Ak Yıldırım, Emre Akkaya, Huseyin Karakurt, Aydın Yıldırım, Ayfer Utku Savaş
BACKGROUND: Obstructive sleep apnea syndrome (OSAS) is reported to be associated with hypertension, coronary artery disease, atrial fibrillation, and heart failure. Galectin-3 plays an important role in the regulation of inflammation, development of cardiac fibrosis and remodeling. A significant relationship between galectin-3 and the total number of coronary plaques and the macrocalcified plaque structures of patients with type 2 DM has been reported. AIM: The aim of this study was to investigate the association between galectin-3 level and coronary plaque burden as well as OSAS severity in patients with obstructive sleep apnea syndrome...
February 2, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28139136/spontaneous-coronary-artery-dissection-challenges-of-coronary-computed-tomography-angiography
#10
Mackram F Eleid, Marysia S Tweet, Phillip M Young, Eric Williamson, Sharonne N Hayes, Rajiv Gulati
BACKGROUND: There is limited understanding of the role of cardiac computed tomography angiography (CCTA) for assessment of patients with spontaneous coronary artery dissection (SCAD). METHODS: In this report we describe the diagnostic utility of CCTA in three young women presenting with signs and symptoms of myocardial ischemia who were eventually diagnosed with SCAD. RESULTS: None of the women had traditional atherosclerotic risk factors...
January 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28130645/subclinical-atherosclerosis-detected-by-coronary-computed-tomographic-angiography-in-qatar-a-comparison-between-qataris-and-south-asian-migrants
#11
Joshua Schulman-Marcus, Ran Heo, Heidi Gransar, Jassim Al Suwaidi, Maryam Alkuwari, Kimberly Elmore, Mille J Gomez, Amin Jayyousi, Mahmoud Zirie, James K Min, Jessica M Peña
PURPOSE: There are limited data regarding subclinical atherosclerosis in Middle Eastern countries. We aimed to describe and compare coronary computed tomographic angiography (CCTA) findings in Qatari native and South Asian migrants at increased risk of coronary artery disease (CAD). METHODS: We performed CCTA in 251 consecutive volunteers (126 South Asian, 125 Qatari, mean age 50.0 ± 7.3 years, 27.1% female) at increased risk of cardiovascular disease. Given differences in baseline risk factors, we employed propensity score matching to create a cohort of 162 subjects for comparative analyses...
January 27, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28130049/automated-and-manual-measurements-of-the-aortic-annulus-with-ecg-gated-cardiac-ct-angiography-prior-to-transcatheter-aortic-valve-replacement-comparison-with-3d-transesophageal-echocardiography
#12
David Guez, Gilda Boroumand, Nicholas J Ruggiero, Praveen Mehrotra, Ethan Joseph Halpern
RATIONALE AND OBJECTIVES: Multimodality evaluation of the aortic annulus is generally advocated to plan for transcatheter aortic valve replacement (TAVR). We compared aortic annular measurements by cardiac computed tomography angiography (cCTA) to three-dimensional transesophageal echocardiography (3D-TEE), and also evaluated the use of semi-automated software for cCTA annular measurements. MATERIALS AND METHODS: A retrospective cohort of 74 patients underwent 3D-TEE and electrocardiogram-gated cCTA of the heart within 30 days for TAVR planning...
January 24, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28122619/obesity-metabolic-syndrome-and-cardiovascular-prognosis-from-the-partners-coronary-computed-tomography-angiography-registry
#13
Edward A Hulten, Marcio Sommer Bittencourt, Ryan Preston, Avinainder Singh, Carla Romagnolli, Brian Ghoshhajra, Ravi Shah, Siddique Abbasi, Suhny Abbara, Khurram Nasir, Michael Blaha, Udo Hoffmann, Marcelo F Di Carli, Ron Blankstein
OBJECTIVE: To investigate the relationship among body mass index (BMI), cardiometabolic risk and coronary artery disease (CAD) among patients undergoing coronary computed tomography angiography (CTA). METHODS: Retrospective cohort study of 1118 patients, who underwent coronary CTA at two centers from September 2004 to October 2011. Coronary CTA were categorized as normal, nonobstructive CAD (<50%), or obstructive CAD (≥50%) in addition to segment involvement (SIS) and stenosis scores...
January 25, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28112409/improving-ccta-based-lesions-hemodynamic-significance-assessment-by-accounting-for-partial-volume-modeling-in-automatic-coronary-lumen-segmentation
#14
Moti Freiman, Hannes Nickisch, Sven Prevrhal, Holger Schmitt, Mani Vembar, Pál Maurovich-Horvat, Patrick Donnelly, Liran Goshen
PURPOSE: The goal of this study was to assess the potential added benefit of accounting for partial volume effects (PVE) in an automatic coronary lumen segmentation algorithm that is used to determine the hemodynamic significance of a coronary artery stenosis from coronary computed tomography angiography (CCTA). MATERIALS AND METHODS: Two sets of data were used in our work: (1) multi-vendor CCTA datasets of 18 subjects from the MICCAI 2012 challenge with automatically generated centerlines and 3 reference segmentations of 78 coronary segments and (2) additional CCTA datasets of 97 subjects with132 coronary lesions, that had invasive reference standard FFR measurements...
January 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28070743/cardiac-ct-angiography-ccta-predicts-left-atrial-appendage-occluder-device-size-and-procedure-outcome
#15
Orly Goitein, Noam Fink, Ilan Hay, Elio Di Segni, Victor Guetta, David Goitein, Yafim Brodov, Eli Konen, Michael Glikson
AIM: To investigate the role of cardiac CT angiography (CCTA) in predicting optimal left atrial appendage (LAA) occluder size and procedure outcome. METHODS AND RESULTS: Thirty-six patients underwent pre-procedural CCTA. CCTA and TEE LAA orifice diameters and perimeters were compared with the implanted device size. CCTA 3D configuration was correlated with procedure outcome. Watchman™ device (N = 18): diameters were 21 ± 4, 26 ± 5 and 25 ± 3 mm for TEE, CCTA and inserted device, respectively...
January 9, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28060223/coronary-plaque-progression-and-regression-in-asymptomatic-african-american-chronic-cocaine-users-with-obstructive-coronary-stenoses-a-preliminary-study
#16
Veit Sandfort, David A Bluemke, Jose Vargas, Jeffrey A Brinker, Gary Gerstenblith, Thomas Kickler, Gang Zheng, Ji Li, Shaoguang Chen, Hong Lai, Elliot K Fishman, Shenghan Lai
OBJECTIVE: Although rapid progression of coronary atherosclerosis was observed in chronic cocaine users, it is unknown whether reduced cocaine use retards the progression of atherosclerosis. We investigated whether reduced cocaine use over a 12-month period was associated with coronary plaque regression in cocaine users. METHODS: Fifteen African American chronic cocaine users with previously coronary computed tomography angiography (CCTA)-confirmed >50% coronary stenosis in Baltimore, Maryland, were enrolled in a study to investigate whether reduced cocaine use is associated with changes in coronary plaque burden over a 12-month period of cash-based incentive intervention, which was implemented to systematically reinforce cocaine abstinence...
January 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28057367/increased-pre-procedural-urinary-microalbumin-is-associated-with-a-risk-for-renal-functional-deterioration-after-coronary-computed-tomography-angiography
#17
Satoshi Isobe, Miyuki Yuba, Hiroaki Mori, Susumu Suzuki, Kimihide Sato, Hideki Ishii, Toyoaki Murohara
BACKGROUND: Urinary microalbumin is a marker for preclinical nephropathy. A percentage change in cystatin C (%CyC) of ≥10% for 24h after tests with contrast media is reportedly an independent predictor for developing contrast-induced nephropathy. We investigated the relationship between the presence of urinary microalbumin and changes in CyC after coronary computed tomography angiography (CCTA). METHODS: Three hundred and thirty-three patients with known or suspected coronary artery disease who scheduled for CCTA using a 70mL of Iopamidol were enrolled...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28053308/evaluation-of-left-pulmonary-artery-sling-associated-cardiovascular-anomalies-and-surgical-outcomes-using-cardiovascular-computed-tomography-angiography
#18
Jiajun Xie, Yu-Hsiang Juan, Qiushi Wang, Jimei Chen, Jian Zhuang, Zhaofeng Xie, Changhong Liang, Yulei Zhu, Zhuliang Yu, Jinglei Li, Sachin S Saboo, Hui Liu
We evaluated the prevalence, image appearance, associated cardiovascular anomalies, and surgical outcomes of left pulmonary artery sling (LPAS) using cardiovascular computed tomography angiography (CCTA). A retrospective search of patients from our database between October 2007 and December 2014 identified 52,200 patients with congenital heart diseases (CHD) referred for CCTA, echocardiography, or magnetic resonance imaging. Clinical information, CCTA findings, associated cardiovascular anomalies, and surgical outcomes were analyzed...
January 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28052860/increased-prevalence-of-coronary-plaque-in-patients-with-psoriatic-arthritis-without-prior-diagnosis-of-coronary-artery-disease
#19
Jiayun Shen, Ka-Tak Wong, Isaac T Cheng, Qing Shang, Edmund K Li, Priscilla Wong, Emily W Kun, Mei Yan Law, Ronald Yip, Isaac Yim, Shirley Ying, Martin Li, Tena K Li, Chun-Kwok Wong, Tracy Y Zhu, Jack Jock-Wai Lee, Mimi Chang, Alex Pui-Wai Lee, Lai-Shan Tam
OBJECTIVES: To evaluate coronary atherosclerosis in patients with psoriatic arthritis (PsA) and control subjects using coronary CT angiography (CCTA). METHODS: Ninety consecutive patients with PsA (male: 56(62.2%); 50.3±11.1 years) were recruited. 240 controls (male: 137(57.1%); 49.6±10.7 years) without known cardiovascular (CV) diseases who underwent CCTA due to chest pain and/or multiple CV risk factors were recruited for comparison. RESULTS: Patients with PsA and controls were matched in age, gender and traditional CV risk factors (all p>0...
January 4, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28047000/th-cd-206-12-image-based-motion-estimation-for-plaque-visualization-in-coronary-computed-tomography-angiography
#20
X Zhang, A Sisniega, W Zbijewski, F Contijoch, E McVeigh, J Stayman
PURPOSE: Visualization and quantification of coronary artery calcification and atherosclerotic plaque benefits from coronary artery motion (CAM) artifact elimination. This work applies a rigid linear motion model to a Volume of Interest (VoI) for estimating motion estimation and compensation of image degradation in Coronary Computed Tomography Angiography (CCTA). METHODS: In both simulation and testbench experiments, translational CAM was generated by displacement of the imaging object (i...
June 2016: Medical Physics
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