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https://www.readbyqxmd.com/read/28984636/coronary-artery-positive-remodeling-in-current-smokers
#1
Anas Alani, Yanting Luo, Rine Nakanishim, Suguru Matsumoto, Matthew J Budoff
BACKGROUND: This study aims to evaluate the association of the coronary artery-positive remodeling (CAPR) observed on cardiac computed tomography angiography (CCTA) with cigarette smoking. PATIENTS AND METHODS: This retrospective case-control study enrolled 178 consecutive patients with CAPR plaque (case group) and 180 consecutive patients with coronary artery plaque, but no positive remodeling (control group). CAPR was evaluated in CCTA images and defined as at least 10% larger vessel diameter at the plaque site compared with a normal reference segment...
October 3, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28981808/evaluation-of-radiation-absorbed-dose-and-image-quality-in-different-retrospective-ecg-gating-acquisition-methods-of-cardiac-ct-angiography
#2
Shojaei Barjouei Nazli, Seyed Mahmoud Reza Aghamiri, Neda Gholizadeh Sendani, Amin Shams Akhtari
Cardiac computed tomography angiography (CCTA) studies have risen concern of radiobiological effects over the patients. Therefore, estimating radiation doses absorbed during CCTA is important. In this study, we compared radiation dose and image quality by using three different retrospective electrocardiography (ECG) protocols. A total of 123 patients undergoing CCTA were divided in three different groups. We used full-dose modulation (CareDose4D) technique in group (1); fixed tube current 200 mAs for group (2); and in group (3), chest circumference was used to adapt tube current (180-200 mAs) and tube potential (100-120 kVp)...
August 22, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28980409/stress-test-to-stemi-utility-of-coronary-cta-in-the-diagnosis-and-management-of-anomalous-right-coronary-artery-from-the-left-coronary-cusp
#3
Anshuman Das, Ajay Joseph, Neeraj Jolly, Dinesh K Kalra
A 42-year-old woman presented to the emergency department with chest pain. Acute coronary syndrome was ruled out. During dobutamine stress echocardiography (DSE), she developed chest pain and inferior ST elevation. Emergent coronary angiography revealed no culprit lesions but did show an anomalous right coronary artery (RCA). Coronary CT angiography (CCTA) confirmed an anomalous RCA arising from the left coronary cusp with a slit-like ostium and interarterial course (ARCA-LCC-IA). Herein, we review the extant literature on ARCA-LCC-IA, its clinical presentation, the vital role of CTA and MRI in its diagnosis, as well as challenges and controversies surrounding management...
October 2017: Echocardiography
https://www.readbyqxmd.com/read/28977374/incremental-prognostic-value-of-coronary-computed-tomography-angiography-over-coronary-calcium-scoring-for-major-adverse-cardiac-events-in-elderly-asymptomatic-individuals
#4
Donghee Han, Bríain Ó Hartaigh, Heidi Gransar, Ji Hyun Lee, Asim Rizvi, Lohendran Baskaran, Joshua Schulman-Marcus, Allison Dunning, Stephan Achenbach, Mouaz H Al-Mallah, Daniel S Berman, Matthew J Budoff, Filippo Cademartiri, Erica Maffei, Tracy Q Callister, Kavitha Chinnaiyan, Benjamin J W Chow, Augustin DeLago, Martin Hadamitzky, Joerg Hausleiter, Philipp A Kaufmann, Gilbert Raff, Leslee J Shaw, Todd C Villines, Yong-Jin Kim, Jonathon Leipsic, Gudrun Feuchtner, Ricardo C Cury, Gianluca Pontone, Daniele Andreini, Hugo Marques, Ronen Rubinshtein, Niree Hindoyan, Erica C Jones, Millie Gomez, Fay Y Lin, Hyuk-Jae Chang, James K Min
Aims: Coronary computed tomography angiography (CCTA) and coronary artery calcium score (CACS) have prognostic value for coronary artery disease (CAD) events beyond traditional risk assessment. Age is a risk factor with very high weight and little is known regarding the incremental value of CCTA over CAC for predicting cardiac events in older adults. Methods and results: Of 27 125 individuals undergoing CCTA, a total of 3145 asymptomatic adults were identified...
July 20, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28973101/coronary-computed-tomography-angiography-vs-functional-stress-testing-for-patients-with-suspected-coronary-artery-disease-a-systematic-review-and-meta-analysis
#5
Andrew J Foy, Sanket S Dhruva, Brandon Peterson, John M Mandrola, Daniel J Morgan, Rita F Redberg
Importance: Coronary computed tomography angiography (CCTA) is a new approach for the diagnosis of anatomical coronary artery disease (CAD), but it is unclear how CCTA performs compared with the standard approach of functional stress testing. Objective: To compare the clinical effectiveness of CCTA with that of functional stress testing for patients with suspected CAD. Data Sources: A systematic literature search was conducted in PubMed and MEDLINE for English-language randomized clinical trials of CCTA published from January 1, 2000, to July 10, 2016...
October 2, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28963687/prognostic-value-of-coronary-atherosclerosis-progression-evaluated-by-coronary-ct-angiography-in-patients-with-stable-angina
#6
Hui Gu, Yang Gao, Zhihui Hou, U Joseph Schoepf, Alan N Snyder, Taylor M Duguay, Ximing Wang, Bin Lu
OBJECTIVES: To investigate the progression of coronary atherosclerosis burden by coronary CT angiography (CCTA) and to demonstrate its association with the incidence of major adverse cardiac events (MACE). METHODS: We retrospectively studied patients with stable angina who had undergone repeat CCTA due to recurrent or worsening symptoms. Lipid-rich, fibrous, calcified and total plaque burden as well as coronary diameter stenosis were quantitatively analysed. The incidence of MACE during follow-up was determined...
September 29, 2017: European Radiology
https://www.readbyqxmd.com/read/28956115/ct-myocardial-perfusion-imaging-ready-for-prime-time
#7
EDITORIAL
Richard A P Takx, Csilla Celeng, U Joseph Schoepf
The detection of functional coronary artery stenosis with coronary CT angiography (CCTA) is suboptimal. Additional CT myocardial perfusion imaging (CT-MPI) may be helpful to identify patients with myocardial ischaemia in whom coronary revascularization therapy would be beneficial. CT-MPI adds incremental diagnostic and prognostic value over obstructive disease on CCTA. It allows for the quantitation of myocardial blood flow and calculation of coronary flow reserve and shows good correlation with (15)O-H2O positron emission tomography and invasive fractional flow reserve...
September 27, 2017: European Radiology
https://www.readbyqxmd.com/read/28955501/associations-between-coronary-and-carotid-artery-atherosclerosis-in-patients-with-inflammatory-joint-diseases
#8
Mona Svanteson, Silvia Rollefstad, Nils Einar Kløw, Jonny Hisdal, Eirik Ikdahl, Anne Grete Semb, Ylva Haig
OBJECTIVE: Low association between cardiac symptoms and coronary artery disease (CAD) in patients with inflammatory joint diseases (IJD) demands for objective markers to improve cardiovascular risk stratification. Our main aim was to evaluate the prevalence and characteristics of CAD in patients with IJD with carotid artery plaques. Furthermore, we aimed to assess associations of carotid ultrasonographic findings and coronary plaques. METHODS: Eighty-six patients (61% female) with IJD (55 with rheumatoid arthritis, 21 with ankylosing spondylitis and 10 with psoriatic arthritis) and carotid artery plaque were referred to coronary CT angiography (CCTA)...
2017: RMD Open
https://www.readbyqxmd.com/read/28914973/comparison-of-mid-to-long-term-clinical-outcomes-between-anatomical-testing-and-usual-care-in-patients-with-suspected-coronary-artery-disease-a-meta-analysis-of-randomized-trials
#9
In-Chang Hwang, Sol Ji Choi, Ji Eun Choi, Eun-Bi Ko, Jae Kyung Suh, Insun Choi, Hyun-Jae Kang, Yong-Jin Kim, Joo Youn Kim
BACKGROUND: Controversies remain regarding clinical outcomes following initial strategies of coronary computed tomography angiography (CCTA) vs usual care with functional testing in patients with suspected coronary artery disease (CAD). HYPOTHESIS: CCTA as initial diagnostic strategy results in better mid- to long-term outcomes than usual care in patients with suspected CAD. METHODS: We searched PubMed, Embase, and Cochrane Library for randomized controlled trials comparing clinical outcomes during ≥6 months' follow-up between initial anatomical testing by CCTA vs usual care with functional testing in patients with suspected CAD...
September 15, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28914747/appropriate-use-criteria-for-cardiac-computed-tomography-does-computed-tomography-have-incremental-value-in-all-appropriate-use-criteria-categories
#10
Fernanda Erthal, Manuja Premaratne, Yeung Yam, Li Chen, Jasmine Lamba, Marissa Keenan, Tony Haddad, Kishu Pharasi, Saipriya Anand, Rob S Beanlands, Ian G Burwash, Girish Dwivedi, Terrence D Ruddy, Benjamin J W Chow
PURPOSE: Cardiac imaging expenditures have come under scrutiny, and a focus on appropriate use criteria (AUC) has arisen to ensure cost-effective resource utilization. Although AUC has been developed by clinical experts, it has not undergone rigorous quality assurance testing to ensure that inappropriate indications for testing yield little clinical benefit. The objective of the study was to evaluate the potential incremental prognostic value of coronary computed tomographic angiography (CCTA) in the different AUC categories...
September 13, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28914744/cardiac-computed-tomography-before-and-after-cardiac-surgery
#11
Fernanda Erthal, Joao R Inacio, Samir Hazra, Vincent Chan, Benjamin J W Chow
Cardiac computed tomography angiography (CCTA) is a noninvasive imaging technique that has been rapidly adopted into clinical practice. Over the past decade, technological advances have improved CCTA accuracy, and there is an increasing amount of data supporting its prognostic value in the assessment of coronary artery disease. Recently, "appropriate use criteria" has been used as a tool to minimize inappropriate testing and reduce patient exposure to unnecessary risk and inconclusive studies. This review will summarize the appropriate uses of CCTA in patients before and after cardiac surgery...
September 13, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28910264/estimation-and-comparison-of-the-radiation-effective-dose-during-coronary-computed-tomography-angiography-examinations-on-single-source-64-mdct-and-dual-source-128-mdct
#12
Daryoush Khoramian, Soroush Sistani
GOAL: To estimate and compare the radiation dose associated with coronary computed tomography angiography (CCTA) examinations on two multi-detector CT scanners (MDCT), 64-MDCT and 128-MDCT, in daily practice. METHODS: Scan parameters of 90 patients undergoing retrospective electrocardiographic gating spiral CCTA exam were recorded during a period on a single-source 64-MDCT and a dual-source 128-MDCT, and average scan parameters were derived that were used for dosimetry...
September 14, 2017: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/28906380/syntax-score-based-on-coronary-computed-tomography-angiography-may-have-a-prognostic-value-in-patients-with-complex-coronary-artery-disease-an-observational-study-from-a-retrospective-cohort
#13
Young Joo Suh, Kyunghwa Han, Suyon Chang, Jin Young Kim, Dong Jin Im, Yoo Jin Hong, Hye-Jeong Lee, Jin Hur, Young Jin Kim, Byoung Wook Choi
The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) score is an invasive coronary angiography (ICA)-based score for quantifying the complexity of coronary artery disease (CAD). Although the SYNTAX score was originally developed based on ICA, recent publications have reported that coronary computed tomography angiography (CCTA) is a feasible modality for the estimation of the SYNTAX score.The aim of our study was to investigate the prognostic value of the SYNTAX score, based on CCTA for the prediction of major adverse cardiac and cerebrovascular events (MACCEs) in patients with complex CAD...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28900781/submillisievert-imaging-protocol-using-full-reconstruction-and-advanced-patient-motion-correction-in-320-row-area-detector-coronary-ct-angiography
#14
Yuko Kawaguchi, Shinichiro Fujimoto, Kazuhisa Takamura, Etsuro Kato, Shoko Suda, Rie Matsumori, Makoto Hiki, Kanako K Kumamaru, Hiroyuki Daida
Radiation exposure remains a concern in the use of coronary CT angiography (CCTA). Full reconstruction (Full) and reconstruction using advanced patient motion correction (APMC) could obtain a lower radiation dose using low tube current scanning in a 320-row Area Detector CT (320-ADCT). The radiation dose for an imaging protocol using Full and APMC in daily practice was estimated. A total of 209 patients who underwent CCTA in 1 rotation scanning with 100 kv and adaptive iterative dose reduction 3D in 320-ADCT were enrolled...
September 12, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28886899/frailty-and-subclinical-coronary-atherosclerosis-the-multicenter-aids-cohort-study-macs
#15
Sai Krishna C Korada, Di Zhao, Martin Tibuakuu, Todd T Brown, Lisa P Jacobson, Eliseo Guallar, Robert K Bolan, Frank J Palella, Joseph B Margolick, Jeremy J Martinson, Matthew J Budoff, Wendy S Post, Erin D Michos
BACKGROUND AND AIMS: Frailty and cardiovascular disease share many risk factors. We evaluated whether frailty is independently associated with subclinical coronary atherosclerosis and whether any relationships differ by HIV-serostatus. METHODS: We studied 976 [62% HIV-infected] male participants of the Multicenter AIDS Cohort Study who underwent assessment of frailty and non-contrast cardiac CT scanning; of these, 747 men also underwent coronary CT angiography (CCTA)...
August 26, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28875364/age-and-sex-based-resource-utilisation-and-costs-in-patients-with-acute-chest-pain-undergoing-cardiac-ct-angiography-pooled-evidence-from-romicat-ii-and-acrin-pa-trials
#16
Fabian Bamberg, Thomas Mayrhofer, Maros Ferencik, Daniel O Bittner, Travis R Hallett, Sumbal Janjua, Christopher L Schlett, John T Nagurney, James E Udelson, Quynh A Truong, Pamela K Woodard, Judd E Hollander, Harold Litt, Udo Hoffmann
OBJECTIVES: To determine resource utilisation according to age and gender-specific subgroups in two large randomized diagnostic trials. METHODS: We pooled patient-specific data from ACRIN-PA 4005 and ROMICAT II that enrolled subjects with acute chest pain at 14 US sites. Subjects were randomized between a standard work-up and a pathway utilizing cardiac computed tomography angiography (CCTA) and followed for the occurrence of acute coronary syndrome (ACS) and resource utilisation during index hospitalisation and 1-month follow-up...
September 5, 2017: European Radiology
https://www.readbyqxmd.com/read/28860894/high-pitch-coronary-ct-angiography-at-70-kvp-adopting-a-protocol-of-low-injection-speed-and-low-volume-of-contrast-medium
#17
Ruiqi Feng, Jiajie Tong, Xiaofei Liu, Yu Zhao, Liang Zhang
OBJECTIVE: To evaluate the feasibility and image quality (IQ) of prospectively high-pitch coronary CT angiography (CCTA) with low contrast medium injection rate at 70 kVp. MATERIALS AND METHODS: One hundred and four patients with suspected coronary artery disease (body mass index < 26 kg/m(2), sinus rhythm and heart rate < 70 beats/min) were prospectively enrolled and randomly divided into two groups. In group A and group B, 28 mL and 40 mL of 370 mgI/mL iodinated contrast media was administrated at a flow rate of 3...
September 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28860893/calcification-remodeling-index-characterized-by-cardiac-ct-as-a-novel-parameter-to-predict-the-use-of-rotational-atherectomy-for-coronary-intervention-of-lesions-with-moderate-to-severe-calcification
#18
Mengmeng Yu, Yuehua Li, Wenbin Li, Zhigang Lu, Meng Wei, Jiayin Zhang
OBJECTIVE: To assess the feasibility of calcification characterization by coronary computed tomography angiography (CCTA) to predict the use of rotational atherectomy (RA) for coronary intervention of lesions with moderate to severe calcification. MATERIALS AND METHODS: Patients with calcified lesions treated by percutaneous coronary intervention (PCI) who underwent both CCTA and invasive coronary angiography were retrospectively included in this study. Calcification remodeling index was calculated as the ratio of the smallest vessel cross-sectional area of the lesion to the proximal reference luminal area...
September 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28855273/acute-chest-pain-evaluation-using-coronary-computed-tomography-angiography-compared-with-standard-of-care-a-meta-analysis-of-randomised-clinical-trials
#19
Carlos A Gongora, Chirag Bavishi, Seth Uretsky, Edgar Argulian
OBJECTIVE: Coronary CT angiography (CCTA) has certain advantages compared with stress testing including greater accuracy in identifying obstructive coronary disease. The aim of the study was to perform a systematical review and meta-analysis comparing CCTA with other standard-of-care (SOC) approaches in evaluation of patients with acute chest pain. METHODS: Electronic databases were systematically searched to identify randomised clinical trials of patients with acute chest pain comparing CCTA with SOC approaches...
August 30, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28844517/coronary-computed-tomographic-angiography-derived-fractional-flow-reserve-based-on-machine-learning-for-risk-stratification-of-non-culprit-coronary-narrowings-in-patients-with-acute-coronary-syndrome
#20
Taylor M Duguay, Christian Tesche, Rozemarijn Vliegenthart, Carlo N De Cecco, Han Lin, Moritz H Albrecht, Akos Varga-Szemes, Domenico De Santis, Ullrich Ebersberger, Richard R Bayer, Sheldon E Litwin, Ellen Hoffmann, Daniel H Steinberg, U Joseph Schoepf
This study investigated the prognostic value of coronary computed tomography angiography (cCTA)-derived fractional flow reserve (CT-FFR) in patients with acute coronary syndrome (ACS) and multivessel disease to gauge significance and guide management of non-culprit lesions. We retrospectively analyzed data of 48 patients (56 ± 10 years, 60% men) who were admitted for symptoms suggestive of ACS and underwent dual-source cCTA followed by invasive coronary angiography with culprit lesion intervention. Culprit lesions were retrospectively identified on cCTA using images obtained during invasive coronary angiography...
October 15, 2017: American Journal of Cardiology
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