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https://www.readbyqxmd.com/read/29454588/diagnostic-performance-of-two-corrected-transluminal-attenuation-gradient-metrics-in-coronary-ct-angiography-for-the-evaluation-of-significant-in-stent-restenosis-by-dual-source-ct-a-validation-study-with-invasive-coronary-angiography
#1
D Wen, J Li, H Zhao, J Li, M Zheng
AIM: To determine the diagnostic potential of transluminal attenuation gradients (TAG) with exclusion of stented coronary segments (TAG-ExS) and TAG-corrected contrast opacification (CCO) excluding stented coronary segments (TAG-CCO-ExS) for the assessment of in-stent restenosis (ISR). MATERIALS AND METHODS: TAG-ExS and TAG-CCO-ExS were calculated in 93 coronary arteries with 190 stents. The diagnostic performances and the incremental values of the two metrics to coronary computed tomography angiography (CCTA) were analysed and compared...
February 14, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29450719/coronary-plaque-characteristics-on-baseline-ct-predict-the-need-for-late-revascularization-in-symptomatic-patients-after-percutaneous-intervention
#2
Mengmeng Yu, Zhigang Lu, Wenbin Li, Meng Wei, Jing Yan, Jiayin Zhang
OBJECTIVES: To assess pre-procedural plaque characteristics as determined by coronary CT angiography (CCTA) and their associations with late revascularization in symptomatic post-procedural patients. METHODS: Symptomatic patients with pre-procedural CCTA were prospectively enrolled and referred for invasive coronary angiography (ICA). Plaque characterization was performed on the basis of baseline CCTA data. Multivariate logistic regression analysis with a stepwise selection method was performed to identify independent predictors of late revascularization...
February 15, 2018: European Radiology
https://www.readbyqxmd.com/read/29447342/diagnosing-coronary-artery-disease-after-a-positive-coronary-computed-tomography-angiography-the-dan-nicad-open-label-parallel-head-to-head-randomized-controlled-diagnostic-accuracy-trial-of-cardiovascular-magnetic-resonance-and-myocardial-perfusion-scintigraphy
#3
L Nissen, S Winther, J Westra, J A Ejlersen, C Isaksen, A Rossi, N R Holm, G Urbonaviciene, L C Gormsen, L H Madsen, E H Christiansen, M Maeng, L L Knudsen, L Frost, L Brix, H E Bøtker, S E Petersen, M Bøttcher
Aims: Perfusion scans after coronary computed tomography angiography (CCTA) in patients with suspected coronary artery disease (CAD) may reduce unnecessary invasive coronary angiographies (ICAs). However, the diagnostic accuracy of perfusion scans after primary CCTA is unknown. The aim of this study was to determine the diagnostic accuracy of cardiac magnetic resonance (CMR) and myocardial perfusion scintigraphy (MPS) against ICA with fractional flow reserve (FFR) in patients suspected of CAD by CCTA...
February 13, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29446681/coronary-ct-angiography-use-in-patients-with-chest-pain-presenting-to-emergency-departments
#4
David C Levin, Laurence Parker, Ethan J Halpern, Vijay M Rao
OBJECTIVE: Previously published reports have shown that coronary CT angiography (CCTA) is a more efficient method of diagnosis than myocardial perfusion imaging (MPI) and stress echocardiography for patients presenting to emergency departments (EDs) with acute chest pain. In light of this evidence, the objective of this study was to examine recent trends in the use of these techniques in EDs. MATERIALS AND METHODS: The nationwide Medicare Part B databases for 2006-2015 were the data source...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29441745/evaluation-of-atherosclerotic-plaque-in-non-invasive-coronary-imaging
#5
REVIEW
Aeshita Dwivedi, Subhi J Al'Aref, Fay Y Lin, James K Min
Coronary artery disease (CAD) is the leading cause of morbidity and mortality worldwide. Over the last decade coronary computed tomography angiography (CCTA) has gained wide acceptance as a reliable, cost-effective and non-invasive modality for diagnosis and prognostication of CAD. Use of CCTA is now expanding to characterization of plaque morphology and identification of vulnerable plaque. Additionally, CCTA is developing as a non-invasive modality to monitor plaque progression, which holds future potential in individualizing treatment...
February 2018: Korean Circulation Journal
https://www.readbyqxmd.com/read/29439144/coronary-computed-tomography-angiography-detection-of-short-and-long-term-outcomes-after-heart-valve-surgery-with-high-risk-cardiovascular-patients
#6
Zhi Zhu, Shuofeng Li
Coronary computed tomography angiography (CCTA) is a promising alternative technique to detect significant coronary artery lesions in high-risk cardiovascular patients with left ventricular dysfunction (left ventricular ejection fractions < 40%) referred for elective valve surgery, while little research about the use of CCTA to detect the outcomes of heart valve surgery was performed. Forty-six consecutive high-risk cardiovascular patients with the New York Heart Association (NYHA) classification were retrospectively studied...
February 8, 2018: Bioscience Reports
https://www.readbyqxmd.com/read/29426987/coronary-ct-angiography-in-patients-with-atrial-fibrillation-standard-dose-and-low-dose-imaging-with-a-high-resolution-whole-heart-ct-scanner
#7
Anna Matveeva, Rainer R Schmitt, Karoline Edtinger, Matthias Wagner, Sebastian Kerber, Thomas Deneke, Michael Uder, Sebastian Barth
OBJECTIVE: To compare image quality, observer confidence, radiation exposure in the standard-dose (SD-CCTA) and low-dose (LD-CCTA) protocols of coronary CT angiography (CCTA) in patients with atrial fibrillation (AF). MATERIAL AND METHODS: CCTA was performed in 303 patients using a CT scanner with 16-cm coverage (111 scans during sinus rhythm (SR); 192 during AF). LD-CCTA was used in 218 patients; SD-CCTA in 85 patients suspected of having coronary artery disease (CAD)...
February 9, 2018: European Radiology
https://www.readbyqxmd.com/read/29417250/using-coronary-ct-angiography-for-guiding-invasive-coronary-angiography-potential-role-to-reduce-intraprocedural-radiation-exposure
#8
Christophe T Arendt, Patricia Tischendorf, Julian L Wichmann, Michael Messerli, Lucas Jörg, Niklas Ehl, Robin F Gohmann, Simon Wildermuth, Thomas J Vogl, Ralf W Bauer
OBJECTIVES: We investigated the potential reduction of patient exposure during invasive coronary angiography (ICA) if the procedure had only been directed to the vessel with at least one ≥ 50% stenosis as described in the CT report. METHODS: Dose reports of 61 patients referred to ICA because of at least one ≥ 50% stenosis on coronary CT angiography (CCTA) were included. Dose-area product (DAP) was documented separately for left (LCA) and right coronary arteries (RCA) by summing up the single DAP for each angiographic projection...
February 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29406941/cardiac-imaging-modalities-and-appropriate-use
#9
REVIEW
Paul Gabriel Peterson, Michael Berge, John P Lichtenberger, Maureen N Hood, Vincent B Ho
Cardiovascular imaging with calcium scoring computed tomography (CT), coronary CT angiography (CCTA), and cardiac MRI (CMR) have advanced rapidly over recent years. These imaging modalities have increased in availability, accessibility, and clinical practicality due to technological advances allowing for significant radiation dose reduction for high-quality CCTA and for rapid and reliable imaging techniques in CMR. Hardware and software developments are continually increasing efficiency and accuracy of postprocessing...
March 2018: Primary Care
https://www.readbyqxmd.com/read/29390498/assessment-of-radiation-safety-in-cardiac-ct-angiography
#10
Yuan-Hao Lee, Po-Yen Chang, Shee Yen Tay, Cheng-Yu Tsai, Po-Hsin Cheng, Wilson T Lao, Wing P Chan
This study investigates the radiation dose and image quality of patients not receiving β-blockers for cardiac CT angiography (CCTA) with or without the optimization of electrocardiographic (ECG) pulsing window. The differences in patient characteristics are also characterized.Normal-weight and obese patients (n = 154) with heart rates between 65 and 80 beats per minutes (bpm) during the prospective axial scanning were enrolled retrospectively. The ECG pulsing windows were set at 50% to 75% (Group A) or 60% to 75% (Group B) of the R-R interval for patients with heart rate variability higher than or not exceeding ±5 bpm, respectively...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29389809/diagnostic-accuracy-of-coronary-computed-tomography-before-aortic-valve-replacement-systematic-review-and-meta-analysis
#11
Kongkiat Chaikriangkrai, Hye Yeon Jhun, Ghanshyam Palamaner Subash Shantha, Aref Bin Abdulhak, Rudhir Tandon, Musab Alqasrawi, Anthony Klappa, Samir Pancholy, Abhishek Deshmukh, Jay Bhama, Gardar Sigurdsson
PURPOSE: In aortic stenosis patients referred for surgical and transcatheter aortic valve replacement (AVR), the evidence of diagnostic accuracy of coronary computed tomography angiography (CCTA) has been limited. The objective of this study was to investigate the diagnostic accuracy of CCTA for significant coronary artery disease (CAD) in patients referred for AVR using invasive coronary angiography (ICA) as the gold standard. MATERIALS AND METHODS: We searched databases for all diagnostic studies of CCTA in patients referred for AVR, which reported diagnostic testing characteristics on patient-based analysis required to pool summary sensitivity, specificity, positive-likelihood ratio, and negative-likelihood ratio...
January 31, 2018: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/29387923/association-between-histological-features-of-epicardial-adipose-tissue-and-coronary-plaque-characteristics-on-computed-tomography-angiography
#12
Atsuhiro Senoo, Toshiro Kitagawa, Shinya Torimaki, Hideya Yamamoto, Kazuhiro Sentani, Shinya Takahashi, Yumiko Kubo, Wataru Yasui, Taijiro Sueda, Yasuki Kihara
The means by which epicardial adipose tissue (EAT) could influence coronary plaque progression biologically remain unclear. We investigated the association between the histological findings of EAT and coronary plaque characteristics assessed by coronary computed tomography angiography (CCTA). We enrolled 34 patients in whom one or more coronary plaques containing non-calcified components were detected on CCTA before cardiac surgery [coronary artery bypass graft (CABG) or non-CABG]. We evaluated visceral adipose tissue (VAT) area, EAT volume, and coronary plaque characteristics including minimum computed tomography density (CTD) and vascular Remodeling Index (RI)...
January 31, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29376102/quantification-of-uncertainty-in-the-assessment-of-coronary-plaque-in-ccta-through-a-dynamic-cardiac-phantom-and-3d-printed-plaque-model
#13
Taylor Richards, Gregory M Sturgeon, Juan Carlos Ramirez-Giraldo, Geoffrey D Rubin, Lynne Hurwitz Koweek, William Paul Segars, Ehsan Samei
The purpose of this study was to develop a dynamic physical cardiac phantom with a realistic coronary plaque to investigate stenosis measurement accuracy under clinically relevant heart-rates. The coronary plaque model (5 mm diameter, 50% stenosis, and 32 mm long) was designed and 3D-printed with tissue equivalent materials (calcified plaque with iodine-enhanced lumen). Realistic cardiac motion was modeled by converting computational cardiac motion vectors into compression and rotation profiles executed by a commercial base cardiac phantom...
January 2018: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29374188/impact-of-left-atrial-appendage-morphology-on-thrombus-formation-after-successful-left-atrial-appendage-occlusion-assessment-with-cardiac-computed-tomography
#14
Wulf Dieker, Michael Behnes, Christian Fastner, Benjamin Sartorius, Annika Wenke, Ishar Sing-Gill, Ibrahim El-Battrawy, Jürgen Kuschyk, Theano Papavassiliu, Ursula Hoffmann, Kambis Mashayekhi, Stefan O Schoenberg, Martin Borggrefe, Thomas Henzler, Ibrahim Akin
A standardized imaging algorithm by cardiac computed tomography angiography (cCTA) (LOVE-view) was used in 30 patients to evaluate the influence of different left atrial appendage (LAA) morphologies on development of thrombosis in the LAA 6 months after implantation of an occlusion device (Watchman or Amplatzer-Cardiac-Plug) in patients with non-valvular atrial fibrillation, CHA2DS2-VASc-Score >1 and a contraindication for oral anticoagulation. The distribution of different LAA morphologies was 40% windsock, 17% broccoli and 43% chicken wing type...
January 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29373248/measurement-of-coronary-bifurcation-angle-with-coronary-ct-angiography-a-phantom-study
#15
Sogol Givehchi, Mohammad Javad Safari, Sock Keow Tan, Mohammad Nazri Bin Md Shah, Fadhli Bin Mohamed Sani, Raja Rizal Azman, Zhonghua Sun, Chai Hong Yeong, Kwan Hoong Ng, Jeannie Hsiu Ding Wong
PURPOSE: Accurate determination of the bifurcation angle and correlation with plaque buildup may lead to the prediction of coronary artery disease (CAD). This work evaluates two techniques to measure bifurcation angles in 3D space using coronary computed tomography angiography (CCTA). MATERIALS AND METHODS: Nine phantoms were fabricated with different bifurcation angles ranging from 55.3° to 134.5°. General X-ray and CCTA were employed to acquire 2D and 3D images of the bifurcation phantoms, respectively...
January 16, 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29365193/prognostic-value-of-coronary-computed-tomographic-angiography-findings-in-asymptomatic-individuals-a-6-year-follow-up-from-the-prospective-multicentre-international-confirm-study
#16
Iksung Cho, Subhi J Al'Aref, Adam Berger, Bríain Ó Hartaigh, Heidi Gransar, Valentina Valenti, Fay Y Lin, Stephan Achenbach, Daniel S Berman, Matthew J Budoff, Tracy Q Callister, Mouaz H Al-Mallah, Filippo Cademartiri, Kavitha Chinnaiyan, Benjamin J W Chow, Augustin DeLago, Todd C Villines, Martin Hadamitzky, Joerg Hausleiter, Jonathon Leipsic, Leslee J Shaw, Philipp A Kaufmann, Gudrun Feuchtner, Yong-Jin Kim, Erica Maffei, Gilbert Raff, Gianluca Pontone, Daniele Andreini, Hugo Marques, Ronen Rubinshtein, Hyuk-Jae Chang, James K Min
Aim: The long-term prognostic benefit of coronary computed tomographic angiography (CCTA) findings of coronary artery disease (CAD) in asymptomatic populations is unknown. Methods and results: From the prospective multicentre international CONFIRM long-term study, we evaluated asymptomatic subjects without known CAD who underwent both coronary artery calcium scoring (CACS) and CCTA (n = 1226). Coronary computed tomographic angiography findings included the severity of coronary artery stenosis, plaque composition, and coronary segment location...
January 20, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29359950/image-quality-in-coronary-computed-tomography-angiography-influence-of-adaptive-statistical-iterative-reconstruction-at-various-radiation-dose-levels
#17
Helle Precht, Oke Gerke, Jesper Thygesen, Kenneth Egstrup, Søren Auscher, Dag Waaler, Jess Lambrechtsen
Background Computed tomography (CT) technology is rapidly evolving and software solution developed to optimize image quality and/or lower radiation dose. Purpose To investigate the influence of adaptive statistical iterative reconstruction (ASIR) at different radiation doses in coronary CT angiography (CCTA) in detailed image quality. Material and Methods A total of 160 CCTA were reconstructed as follows: 55 scans with filtered back projection (FBP) (650 mA), 51 scans (455 mA) with 30% ASIR (ASIR30), and 54 scans (295 mA) with 60% ASIR (ASIR60)...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29355991/a-functionally-personalized-boundary-condition-model-to-improve-estimates-of-fractional-flow-reserve-with-ct-ct-ffr
#18
Moti Freiman, Hannes Nickisch, Holger Schmitt, Pál Maurovich-Horvat, Patrick M Donnelly, Mani Vembar, Liran Goshen
PURPOSE: The purpose of this study is to develop and evaluate a functionally personalized boundary condition (BC) model for estimating the fractional flow reserve (FFR) from coronary computed tomography angiography (CCTA) using flow simulation (CT-FFR). MATERIALS AND METHODS: CCTA data of 90 subjects with subsequent invasive FFR in 123 lesions within 21 days (range: 0-83) were retrospectively collected. We developed a functionally-personalized BC model accounting specifically for the coronary micro-vascular resistance dependency on the coronary outlets pressure suggested by several physiological studies...
January 22, 2018: Medical Physics
https://www.readbyqxmd.com/read/29351655/establishing-diagnostic-reference-levels-for-cardiac-computed-tomography-angiography-in-saudi-arabia
#19
Ali B Alhailiy, Peter L Kench, Mark F McEntee, Patrick C Brennan, Elaine A Ryan
Cardiac computed tomography angiography (CCTA) is a commonly used diagnostic imaging tool for cardiovascular disease. Despite constant improvements to imaging technologies, the radiation dose to patients remains a concern when using this procedure. Diagnostic reference levels (DRLs) are used as a trigger to identify and alert individual facilities that are using high doses during CT. This study aims to assess patient radiation dose and establish new national DRLs (NDRL) associated with CCTA in Saudi clinical practices...
January 17, 2018: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29349698/third-generation-dual-source-ct-enables-accurate-diagnosis-of-coronary-restenosis-in-all-size-stents-with-low-radiation-dose-and-preserved-image-quality
#20
Yuehua Li, Mengmeng Yu, Wenbin Li, Zhigang Lu, Meng Wei, Jiayin Zhang
OBJECTIVES: To investigate the diagnostic performance of low dose stent imaging in patients with large (≥ 3 mm) and small (< 3 mm) calibre stents by third-generation dual-source CT. METHODS: Symptomatic patients suspected of having in-stent restenosis (ISR) were prospectively enrolled. Coronary computed tomography angiography (CCTA) and invasive coronary angiography (ICA) were performed within 1 month for correlation. Binary ISR was defined as an in-stent neointimal proliferation with diameter stenosis ≥ 50%...
January 18, 2018: European Radiology
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