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Cardiac MR

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https://www.readbyqxmd.com/read/28640443/pathophysiology-of-aortic-stenosis-and-mitral-regurgitation
#1
Gianluca L Perrucci, Marco Zanobini, Paola Gripari, Paola Songia, Bayan Alshaikh, Elena Tremoli, Paolo Poggio
The global impact of the spectrum of valve diseases is a crucial, fast-growing, and underrecognized health problem. The most prevalent valve diseases, requiring surgical intervention, are represented by calcific and degenerative processes occurring in heart valves, in particular, aortic and mitral valve. Due to the increasing elderly population, these pathologies will gain weight in the global health burden. The two most common valve diseases are aortic valve stenosis (AVS) and mitral valve regurgitation (MR)...
June 18, 2017: Comprehensive Physiology
https://www.readbyqxmd.com/read/28637706/endothelial-mineralocorticoid-receptor-contributes-to-systolic-dysfunction-induced-by-pressure-overload-without-modulating-cardiac-hypertrophy-or-inflammation
#2
Ane M Salvador, M Elizabeth Moss, Mark Aronovitz, Kathleen B Mueller, Robert M Blanton, Iris Z Jaffe, Pilar Alcaide
Heart Failure (HF) is associated with increased circulating levels of aldosterone and systemic inflammation. Mineralocorticoid receptor (MR) antagonists block aldosterone action and decrease mortality in patients with congestive HF However, the molecular mechanisms underlying the therapeutic benefits of MR antagonists remain unclear. MR is expressed in all cell types in the heart, including the endothelial cells (EC), in which aldosterone induces the expression of intercellular adhesion molecule 1 (ICAM-1)...
June 2017: Physiological Reports
https://www.readbyqxmd.com/read/28634521/a-review-of-echocardiograms-in-hypertensive-patients-greater-than-60-years-in-a-community-based-family-medicine-program
#3
Shideh Doroudi, Michael D DeLisi, Vincent A DeBari
Background: Heart disease as a result of Hypertension is known to occur. Anatomical and functional changes of the heart can easily be detected by echocardiography, which is a safe and readily available study. Objectives: The aims of this study were to evaluate the prevalence of common echocardiographic changes in chronic hypertensive patients and to compare these changes in male and female populations. Design/methods: The study was a community-based cross-sectional study, on 227 hypertensive patients, 60 years and older, seen in St...
January 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28631080/comparison-of-volumetric-and-functional-parameters-in-simultaneous-cardiac-pet-mr-feasibility-of-volumetric-assessment-with-residual-activity-from-prior-pet-ct
#4
C Lücke, B Oppolzer, P Werner, B Foldyna, P Lurz, T Jochimsen, B Brenneis, L Lehmkuhl, B Sattler, M Grothoff, H Barthel, O Sabri, M Gutberlet
OBJECTIVE: To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT. METHODS: Twenty-nine patients (23 men, age 58±17 years) underwent cardiac PET/MRI either directly after a non-cardiac PET/CT with homogenous cardiac [18F] FDG uptake (n=20) or for viability assessment (n=9)...
June 19, 2017: European Radiology
https://www.readbyqxmd.com/read/28630889/subspace-aware-recovery-of-low-rank-and-jointly-sparse-signals
#5
Sampurna Biswas, Soura Dasgupta, Raghuraman Mudumbai, Mathews Jacob
We consider the recovery of a matrix X, which is simultaneously low rank and joint sparse, from few measurements of its columns using a two-step algorithm. Each column of X is measured using a combination of two measurement matrices; one which is the same for every column, while the the second measurement matrix varies from column to column. The recovery proceeds by first estimating the row subspace vectors from the measurements corresponding to the common matrix. The estimated row subspace vectors are then used to recover X from all the measurements using a convex program of joint sparsity minimization...
March 2017: IEEE Transactions on Computational Imaging
https://www.readbyqxmd.com/read/28626146/mitral-valve-structure-in-addition-to-myocardial-viability-determines-the-outcome-of-functional-mitral-regurgitation-after-coronary-artery-bypass-grafting
#6
Shohei Yoshida, Satsuki Fukushima, Shigeru Miyagawa, Teruya Nakamura, Yasushi Yoshikawa, Hiroki Hata, Shunsuke Saito, Daisuke Yoshioka, Keitaro Domae, Noriyuki Kashiyama, Kouji Yamamoto, Ayumi Shintani, Satoshi Nakatani, Koichi Toda, Yoshiki Sawa
BACKGROUND: Coronary artery bypass grafting (CABG) reduces functional mitral regurgitation (MR) associated with ischemic heart disease, although the predictive factors or mechanisms of reversibility of functional MR after CABG are not fully understood.We investigated whether mitral valve structure is associated with the outcome of functional MR after CABG.Methods and Results:From a consecutive series of 98 patients with mild-moderate functional MR preoperatively who underwent isolated CABG, we enrolled 66 patients who were followed up for >1 year postoperatively using echocardiography...
June 16, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28624396/hybrid-magnetic-resonance-imaging-and-positron-emission-tomography-with-fluorodeoxyglucose-to-diagnose-active-cardiac-sarcoidosis
#7
Marc R Dweck, Ronan Abgral, Maria Giovanna Trivieri, Philip M Robson, Nicolas Karakatsanis, Venkatesh Mani, Anna Palmisano, Marc A Miller, Anuradha Lala, Helena L Chang, Javier Sanz, Johanna Contreras, Jagat Narula, Valentin Fuster, Maria Padilla, Zahi A Fayad, Jason C Kovacic
OBJECTIVES: The purpose of this study was to explore the diagnostic usefulness of hybrid cardiac magnetic resonance (CMR) and positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) for active cardiac sarcoidosis. BACKGROUND: Active cardiac sarcoidosis (aCS) is underdiagnosed and has a high mortality. METHODS: Patients with clinical suspicion of aCS underwent hybrid CMR/PET with late gadolinium enhancement (LGE) and FDG to assess the pattern of injury and disease activity, respectively...
June 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28624332/comparison-of-magnetic-resonance-feature-tracking-with-cspamm-harp-for-the-assessment-of-global-and-regional-layer-specific-strain
#8
Daniel L R Kuetting, Andreas Feisst, Darius Dabir, Rami Homsi, Alois M Sprinkart, Julian Luetkens, Hans H Schild, Daniel K Thomas
PURPOSE: Layer specific strain assessment is increasingly being employed clinically. Cardiac magnetic resonance (MR) Feature Tracking (FT) is considered to be an adequate alternative for strain assessment. The aim of this study is to investigate the feasibility of FT derived layer specific strain assessment. METHODS: CSPAMM and SSFP-Cine sequences were acquired in 38 individuals (19 patients with HFpEF, 19 controls) in identical midventricular short-axis locations...
June 8, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28620752/fatty-metaplasia-quantification-and-impact-on-regional-myocardial-function-as-assessed-by-advanced-cardiac-mr-imaging
#9
Tomas Lapinskas, Bernhard Schnackenburg, Marc Kouwenhoven, Rolf Gebker, Alexander Berger, Remigijus Zaliunas, Burkert Pieske, Sebastian Kelle
OBJECTIVE: This study aimed to investigate the advantages of recently developed cardiac imaging techniques of fat-water separation and feature tracking to characterize better individuals with chronic myocardial infarction (MI). MATERIALS AND METHODS: Twenty patients who had a previous MI underwent CMR imaging. The study protocol included routine cine and late gadolinium enhancement (LGE) technique. In addition, mDixon LGE imaging was performed in every patient. Left ventricular (LV) circumferential (EccLV) and radial (ErrLV) strain were calculated using dedicated software (CMR(42), Circle, Calgary, Canada)...
June 15, 2017: Magma
https://www.readbyqxmd.com/read/28614263/misdiagnosed-anomalous-left-coronary-artery-from-the-pulmonary-artery-as-endocardial-fibroelastosis-in-infancy-a-case-series
#10
Fan Ma, Kaiyu Zhou, Xiaoqing Shi, Xiaoqing Wang, Yi Zhang, Yifei Li, Yimin Hua, Chuan Wang
INTRODUCTION: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare but severe congenital cardiac malformation. The prognosis mainly depends on the early and accurate diagnosis and treatment. However, without a typical and specific clinical manifestation in early stage, ALCAPA has a higher rate of false initial diagnosis. DIAGNOSTIC AND THERAPEUTIC PROCEDURE: Three infants with impaired left ventricle (LV) function, LV enlargement, mitral valve regurgitation (MR), and LV endocardium thickness were initially diagnosed as endocardial fibroelastosis (EFE)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28613164/model-based-generation-of-large-databases-of-cardiac-images-synthesis-of-pathological-cine-mr-sequences-from-real-healthy-cases
#11
Nicolas Duchateau, Maxime Sermesant, Herve Delingette, Nicholas Ayache
Collecting large databases of annotated medical images is crucial for the validation and testing of feature extraction, statistical analysis and machine learning algorithms. Recent advances in cardiac electromechanical modeling and image synthesis provided a framework to generate synthetic images based on realistic mesh simulations. Nonetheless, their potential to augment an existing database with large amounts of synthetic cases requires further investigation. We build upon these works and propose a revised scheme for synthesizing pathological cardiac sequences from real healthy sequences...
June 9, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28612206/temperature-corrected-postmortem-3-t-mr-quantification-of-histopathological-early-acute-and-chronic-myocardial-infarction-a-feasibility-study
#12
Anders Persson, John Baeckmann, Johan Berge, Christian Jackowski, Marcel Warntjes, Wolf-Dieter Zech
The goal of the present study was to evaluate if quantitative postmortem cardiac 3-T magnetic resonance (QPMCMR) T1 and T2 relaxation times and proton density values of histopathological early acute and chronic myocardial infarction differ to the quantitative values of non-pathologic myocardium and other histopathological age stages of myocardial infarction with regard to varying corpse temperatures. In 60 forensic corpses (25 female, 35 male), a cardiac 3-T MR quantification sequence was performed prior to autopsy and cardiac dissection...
June 13, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28611666/mineralocorticoid-receptor-signaling-as-a-therapeutic-target-for-renal-and-cardiac-fibrosis
#13
REVIEW
Greg H Tesch, Morag J Young
Activation of the mineralocorticoid receptor (MR) plays important roles in both physiological and pathological events. Blockade of MR signaling with MR antagonists (MRAs) has been used clinically to treat kidney and cardiac disease associated with hypertension and other chronic diseases, resulting in suppression of fibrosis in these organs. However, the current use of steroidal MRAs has been limited by off target effects on other hormone receptors or adverse effects on kidney tubular function. In this review, we summarize recent insights into the profibrotic roles of MR signaling in kidney and cardiovascular disease...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28604833/chest-mri-under-pulsatile-flow-ventilation-a-new-promising-technique
#14
Catherine Beigelman-Aubry, Nicolas Peguret, Matthias Stuber, Jean Delacoste, Bastien Belmondo, Alban Lovis, Julien Simons, Olivier Long, Kathleen Grant, Gregoire Berchier, Chantal Rohner, Gabriele Bonanno, Simone Coppo, Juerg Schwitter, Mahmut Ozsahin, Salah Qanadli, Reto Meuli, Jean Bourhis
OBJECTIVES: Magnetic resonance imaging (MRI) of the chest has long suffered from its sensitivity to respiratory and cardiac motion with an intrinsically low signal to noise ratio and a limited spatial resolution. The purpose of this study was to perform chest MRI under an adapted non invasive pulsatile flow ventilation system (high frequency percussive ventilation, HFPV®) allowing breath hold durations 10 to 15 times longer than other existing systems. METHODS: One volunteer and one patient known for a thymic lesion underwent a chest MRI under ventilation percussion technique (VP-MR)...
2017: PloS One
https://www.readbyqxmd.com/read/28593398/localization-of-angiosarcoma-by-peri-operative-transesophageal-echocardiography
#15
Yi-Chun Chen
Transthoracic echocardiography (TTE), computed tomography (CT) and magnetic resonance (MR) cannot always clearly identify angiosarcoma. A 22 year old woman presented with dyspnea. Preoperative TTE showed no tumor, and CT and MR both gave the impression that an extra-cardiac, mediastinal tumor was present. Transesophageal echocardiography (TEE), performed during surgery showed an intra-cardiac tumor, which was a well-delineated mass at the intra-ventricular groove of the right heart and surrounding the superior vena cava...
June 7, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28587541/evaluation-of-left-ventricular-strain-in-patients-with-dilated-cardiomyopathy
#16
Yaohan Yu, Sisi Yu, Xuepei Tang, Haibo Ren, Shuhao Li, Qian Zou, Fakui Xiong, Tian Zheng, Lianggeng Gong
Objective Dilated cardiomyopathy (DCM) can cause structural and functional changes in the left ventricle (LV). In this study, we evaluated whether cardiac magnetic resonance tissue-tracking (MR-TT) can be applied to the detection of LV abnormalities in patients with DCM. Methods We used MR-TT to analyze the global peak radial strain (GPRS), global peak circumferential strain (GPCS), and global peak longitudinal strain (GPLS) in every segment of the LV in 23 patients with DCM and 25 controls. The LV ejection fraction was also measured as a function indicator...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28582370/isolated-neurofibroma-of-the-orbit-case-report-and-literature-review
#17
Puneet S Braich, Jared C Donaldson, Gurtej S Bajaj, William H Bearden
PURPOSE: To summarize the clinical, radiographic, and intraoperative characteristics of isolated neurofibromas of the orbit (INFO) in the literature and report a case of INFO. METHODS: Case report and a systematic review of the literature. RESULTS: A total of 45 patients were identified from 18 previous studies. There was no sex predilection and mean ages were between 32.3 and 40.0 years with a standard deviation of 9.8 to 19.5 years, median age was 32 to 38 years with a range of 1...
June 2, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28580809/cardiovascular-imaging-environment-will-the-future-be-cloud-based
#18
Nadine Kawel-Boehm, David A Bluemke
In cardiovascular CT and MR imaging large datasets have to be stored, post-processed, analyzed and distributed. Beside basic assessment of volume and function in cardiac magnetic resonance imaging e.g., more sophisticated quantitative analysis is requested requiring specific software. Several institutions cannot afford various types of software and provide expertise to perform sophisticated analysis. Areas covered: Various cloud services exist related to data storage and analysis specifically for cardiovascular CT and MR imaging...
June 13, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28580695/non-contrast-enhanced-peripheral-mr-angiography-using-velocity-selective-excitation
#19
Dongchan Kim, Hyunseok Seo, Jaejin Cho, Kinam Kwon, Yeji Han, HyunWook Park
PURPOSE: To develop a new non-contrast-enhanced peripheral MR angiography that provides a high contrast angiogram without using electrocardiography triggering and saturation radiofrequency pulses. METHODS: A velocity-selective excitation technique is used in conjunction with the golden-angle radial sampling scheme. The signal amplitude varies according to the velocity of the flow by the velocity-selective excitation technique. Because the arterial blood velocity varies depending on the cardiac phase, the acquired data can be classified into systolic and diastolic phase based on the signal amplitude of the artery...
June 5, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28574808/fetal-cardiac-us-techniques-and-normal-anatomy-correlated-with-adult-ct-and-mr-imaging
#20
Neel Patel, Evan Narasimhan, Anne Kennedy
Congenital heart disease (CHD) is an important cause of childhood mortality. Despite the widespread use of ultrasonography (US) as a screening tool, the prenatal detection rate is suboptimal. Improvement of the initial screening examination, which is performed in low-risk populations and often interpreted by community radiologists, targets a point in the screening process that is likely to have the largest population effect. If the goal of community-based screenings is to detect cases that may be abnormal and refer those to specialized centers for complete assessment, it is logical to use a checklist to confirm normal anatomy...
June 2, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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