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Cardiac MR

Felix Kreidel, Hannes Alessandrini, Peter Wohlmuth, Michael Schmoeckel, Stephan Geidel
OBJECTIVE: To assess the results of catheter-based and surgical reintervention in primary mitral regurgitation (PMR) after failed MitraClip therapy. METHODS: We report on 21 consecutive symptomatic patients with PMR (median age 78 years) who underwent either repeat MitraClip therapy (n=7) or mitral valve surgery (n=14) after failure of the index procedure with 1-2 MitraClip implantations. At the time of reinterventions, 193 [IQR: 32 to 622] days after index procedure, patients had recurrent or persistent grade 3 MR...
March 12, 2018: Seminars in Thoracic and Cardiovascular Surgery
Dae-Hyun Kim, Deok-Soo Lee, Hyun-Wook Nah, Jae-Kwan Cha
BACKGROUND: A significant proportion of patients with mild ischemic stroke become disabled despite receiving intravenous thrombolytic therapy. The purpose of this study was to assess the clinical and radiological factors associated with unfavorable outcomes in patients with minor ischemic stroke that received intravenous recombinant tissue plasminogen activator (rt-PA) therapy. METHODS: We identified anterior circulation stroke patients with initial National Institutes of Health Stroke Scale (NIHSS) scores ≤5 who received intravenous thrombolysis within 4...
March 15, 2018: BMC Neurology
Robin Bülow, Till Ittermann, Marcus Dörr, Axel Poesch, Sönke Langner, Henry Völzke, Norbert Hosten, Marc Dewey, Robin Bülow
OBJECTIVES: Reference ranges of left ventricular (LV) parameters from cardiac magnetic resonance (CMR) were established to investigate the impact of ageing and hypertension as important determinants of cardiac structure and function. METHODS: One thousand five hundred twenty-five contrast-enhanced CMRs were conducted in the Study of Health in Pomerania. LV end-diastolic volume (LVEDV), end-systolic volume (LVESV), stroke volume (LVSV), ejection fraction (LVEF), and myocardial mass (LVMM) were determined using long- and short-axis steady-state free-precession sequences...
March 14, 2018: European Radiology
Jochen von Spiczak, Mareike Gastl, Ioannis Kapos, Hatem Alkadhi, Robert Manka
No abstract text is available yet for this article.
March 15, 2018: International Journal of Cardiovascular Imaging
Hidenori Takeshima, Kanako Saitoh, Shuhei Nitta, Taichiro Shiodera, Tomoyuki Takeguchi, Shuhei Bannae, Shigehide Kuhara
PURPOSE: Dynamic MR techniques, such as cardiac cine imaging, benefit from shorter acquisition times. The goal of the present study was to develop a method that achieves short acquisition times, while maintaining a cost-effective reconstruction, for dynamic MRI. k - t sensitivity encoding (SENSE) was identified as the base method to be enhanced meeting these two requirements. METHODS: The proposed method achieves a reduction in acquisition time by estimating the spatiotemporal (x - f) sensitivity without requiring the acquisition of the alias-free signals, typical of the k - t SENSE technique...
March 13, 2018: Magnetic Resonance in Medical Sciences: MRMS
Philipp E Bartko, Noemi Pavo, Ana Pérez-Serradilla, Henrike Arfsten, Stephanie Neuhold, Raphael Wurm, Irene M Lang, Guido Strunk, Jacob P Dal-Bianco, Robert A Levine, Martin Hülsmann, Georg Goliasch
Aims: Secondary mitral regurgitation (MR) drives adverse remodelling towards late heart failure stages. Little is known about the evolution of MR under guideline-directed therapy (GDT) and its relation to cardiac remodelling and outcome. We therefore aimed to assess incidence, impact, and predictors of progressive secondary MR in patients under GDT. Methods and results: We prospectively enrolled 249 patients with chronic heart failure and reduced ejection fraction receiving GDT in this long-term observational study...
March 9, 2018: European Heart Journal Cardiovascular Imaging
Roxanne Labranche, Guillaume Gilbert, Milena Cerny, Kim-Nhien Vu, Denis Soulières, Damien Olivié, Jean-Sébastien Billiard, Takeshi Yokoo, An Tang
Iron overload is a systemic disorder and is either primary (genetic) or secondary (exogenous iron administration). Primary iron overload is most commonly associated with hereditary hemochromatosis and secondary iron overload with ineffective erythropoiesis (predominantly caused by β-thalassemia major and sickle cell disease) that requires long-term transfusion therapy, leading to transfusional hemosiderosis. Iron overload may lead to liver cirrhosis and hepatocellular carcinoma, in addition to cardiac and endocrine complications...
March 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Rasmus Stilling Tougaard, Esben Søvsø Szocska Hansen, Christoffer Laustsen, Jakob Lindhardt, Marie Schroeder, Hans Erik Bøtker, Won Yong Kim, Henrik Wiggers, Hans Stødkilde-Jørgensen
PURPOSE: Deranged metabolism is now recognized as a key causal factor in a variety of heart diseases, and is being studied extensively. However, invasive methods may alter metabolism, and conventional imaging techniques measure tracer uptake but not downstream metabolism. These challenges may be overcome by hyperpolarized MR, a noninvasive technique currently crossing the threshold into human trials. The aim of this study was to image metabolic changes in the heart in response to endogastric glucose bolus and to acute hypertension...
March 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Patrick Krumm, Stefanie Mangold, Sergios Gatidis, Konstantin Nikolaou, Felix Nensa, Fabian Bamberg, Christian la Fougère
Combined PET/MRI is a novel imaging method integrating the advances of functional and morphological MR imaging with PET applications that include assessment of myocardial viability, perfusion, metabolism of inflammatory tissue and tumors, as well as amyloid deposition imaging. As such, PET/MRI is a promising tool to detect and characterize ischemic and non-ischemic cardiomyopathies. To date, the greatest benefit may be expected for diagnostic evaluation of systemic diseases and cardiac masses that remain unclear in cardiac MRI, as well as for clinical and scientific studies in the setting of ischemic cardiomyopathies...
March 10, 2018: Japanese Journal of Radiology
Pinar Yilmaz, Karel Wallecan, Wisnumurti Kristanto, Jean-Paul Aben, Adriaan Moelker
The purpose of this study was to evaluate a semi-automatic right ventricle segmentation method on short-axis cardiac cine MR images which segment all right ventricle contours in a cardiac phase using one seed contour. Twenty-eight consecutive short-axis, four-chamber, and tricuspid valve view cardiac cine MRI examinations of healthy volunteers were used. Two independent observers performed the manual and automatic segmentations of the right ventricles. Analyses were based on the ventricular volume and ejection fraction of the right heart chamber...
March 9, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Vincenzo Positano, Antonella Meloni, Francesca Macaione, Maria Filomena Santarelli, Laura Pistoia, Andrea Barison, Salvatore Novo, Alessia Pepe
To compare image analysis methods for the assessment of left ventricle non-compaction from cardiac magnetic resonance (CMR) imaging. CMR images were analyzed in 20 patients and 10 normal subjects. A reference model of the MR signal was introduced and validated based on image data. Non-compact (NC) myocardium size and distribution were assessed by tracing a single, continuous contour delimiting trabeculated region (Jacquier) or by one-by-one selection of trabeculae (Grothoff). The global non-compact/compact (NC/C) ratio, the NC mass, and the segmental NC/C ratio were assessed...
March 9, 2018: International Journal of Cardiovascular Imaging
John Whitaker, Cory M Tschabrunn, Jihye Jang, Eran Leshem, Mark O'Neill, Warren J Manning, Elad Anter, Reza Nezafat
BACKGROUND: Myocardial infarction (MI) survivors are at risk of complications including heart failure and malignant arrhythmias. PURPOSE: We undertook serial imaging of swine following MI with the aim of characterizing the longitudinal left ventricular (LV) remodeling in a translational model of ischemia-reperfusion-mediated MI. ANIMAL MODEL: Eight Yorkshire swine underwent mid left anterior descending coronary artery balloon occlusion to create an ischemia-reperfusion experimental model of MI...
March 9, 2018: Journal of Magnetic Resonance Imaging: JMRI
Mladjan Golubovic, Radmilo Jankovic, Dusan Sokolovic, Vladan Cosic, Vesna Maravic, Tomislav Kostic, Zoran Perisic, Nebojsa Ladjevic
OBJECTIVE: We evaluated the utility of preoperative mid-regional pro-adrenomedulin (MR-proADM) and cardiac troponin T (TnT) for improved detection of patients at high risk for perioperative cardiac events and mortality after major non-cardiac surgery. SUBJECTS AND METHODS: This prospective, single-center, observational study enrolled 79 patients undergoing major non-cardiac surgery. After initial clinical assessment (clinical history, physical examination, echocardiogram, blood tests, and chest X-ray), mid-regional pro-adrenomedulin and high sensitivity troponin T (hsTnT) were measured within 48 hours prior to surgery by immunoluminometric and electrochemiluminescence-immuno assay...
March 7, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
Wui K Chong, Virginie Papadopoulou, Paul A Dayton
Microbubble ultrasound contrast agents (UCAs) were recently approved by the Food and Drug administration for non-cardiac imaging. The physical principles of UCAs, methods of administration, dosage, adverse effects, and imaging techniques both current and future are described. UCAs consist of microbubbles in suspension which strongly interact with the ultrasound beam and are readily detectable by ultrasound imaging systems. They are confined to the blood pool when administered intravenously, unlike iodinated and gadolinium contrast agents...
March 5, 2018: Abdominal Radiology
Gabriela Spilberg, Jan-Erik Scholtz, Udo Hoffman, David A Rosman, James Brink, Joshua A Hirsch, Brian B Ghoshhajra
No abstract text is available yet for this article.
February 28, 2018: Journal of the American College of Radiology: JACR
Shana R Watson, James D Dormer, Baowei Fei
There has been an increasing interest in studying cardiac fibers in order to improve the current knowledge regarding the mechanical and physiological properties of the heart during heart failure (HF), particularly early HF. Having a thorough understanding of the changes in cardiac fiber orientation may provide new insight into the mechanisms behind the progression of left ventricular (LV) remodeling and HF. We conducted a systematic review on various technologies for imaging cardiac fibers and its link to HF...
March 2, 2018: Heart Failure Reviews
Alexander Liu, Rohan S Wijesurendra, Joanna M Liu, Andreas Greiser, Michael Jerosch-Herold, John C Forfar, Keith M Channon, Stefan K Piechnik, Stefan Neubauer, Rajesh K Kharbanda, Vanessa M Ferreira
BACKGROUND: Novel cardiac magnetic resonance (CMR) stress T1 mapping can detect ischemia and myocardial blood volume changes without contrast agents and may be a more comprehensive ischemia biomarker than myocardial blood flow. OBJECTIVES: This study describes the performance of the first prospective validation of stress T1 mapping against invasive coronary measurements for detecting obstructive epicardial coronary artery disease (CAD), defined by fractional flow reserve (FFR <0...
March 6, 2018: Journal of the American College of Cardiology
Semi Ozturk, Ahmet Seyfeddin Gurbuz, Suleyman Cagan Efe, Raim Iliaz, Mutse Banzragch, Kadir Demir
Background Neurologic and liver involvement in Wilson's disease (WD) is well-documented, however, few reports demonstrated cardiac involvement. Tpe and Tpe/QT are new measures of ventricular repolarization which were recently suggested as predictor of arrythmogenesis. We aimed to evaluate ventricular depolarization and repolarization parameters including QT, QTc, Tpe intervals, Tpe/QT, Tpe/QTc ratios, and QT dispersion (QTd) in patients with WD. Materials and methods Thirty-five patients with WD and 30 healthy controls were included in the study...
March 1, 2018: Acta Clinica Belgica
Ibolya Csecs, Csilla Czimbalmos, Ferenc Imre Suhai, Róbert Mikle, Arash Mirzahosseini, Zsófia Dohy, Andrea Szűcs, Anna Réka Kiss, Tamás Simor, Attila Tóth, Béla Merkely, Hajnalka Vágó
While cardiac magnetic resonance (CMR) is the reference method to evaluate left and right ventricular functions, volumes and masses, there is no widely accepted method for the quantitative analysis of trabeculae and papillary muscles (TPM). The aim of this study was to investigate the effect of TPM quantification on left and right ventricular CMR values in a normal cohort and to investigate interobserver variability of threshold-based (TB) analysis by three independent observers with variant experience in CMR...
February 28, 2018: International Journal of Cardiovascular Imaging
Jennifer S McDonald, Robert J McDonald, Jacob B Ekins, Antony S Tin, Sylvain Costes, Tamara M Hudson, Dana J Schroeder, Kevin Kallmes, Scott H Kaufmann, Philip M Young, Aiming Lu, Ramanathan Kadirvel, David F Kallmes
[This corrects the article DOI: 10.1371/journal.pone.0190890.].
2018: PloS One
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