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Cardiac CTA

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https://www.readbyqxmd.com/read/28314613/improved-image-quality-with-simultaneously-reduced-radiation-exposure-knowledge-based-iterative-model-reconstruction-algorithms-for-coronary-ct-angiography-in-a-clinical-setting
#1
Florian André, Philipp Fortner, Mani Vembar, Dirk Mueller, Wolfram Stiller, Sebastian J Buss, Hans-Ulrich Kauczor, Hugo A Katus, Grigorios Korosoglou
BACKGROUND: The aim of this study was to assess the potential for radiation dose reduction using knowledge-based iterative model reconstruction (K-IMR) algorithms in combination with ultra-low dose body mass index (BMI)-adapted protocols in coronary CT angiography (coronary CTA). METHODS: Forty patients undergoing clinically indicated coronary CTA were randomly assigned to two groups with BMI-adapted (I: <25.0 kg/m(2), II: <28.0 kg/m(2), III: <30.0 kg/m(2), IV: ≥30...
February 23, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28296294/electrocardiogram-gated-coronary-ct-angiography-dose-estimates-using-impact
#2
Masanao Kobayashi, Yasuki Asada, Kosuke Matsubara, Shouichi Suzuki, Kichiro Koshida, Yuta Matsunaga, Tomonobu Haba, Ai Kawaguchi, Hiroshi Toyama, Ryoichi Kato
The primary study objective was to assess radiation doses using a modified form of the Imaging Performance Assessment of Computed Tomography (CT) scanner (ImPACT) patient dosimetry for cardiac applications on an Aquilion ONE ViSION Edition scanner, including the Ca score, target computed tomography angiography (CTA), prospective CTA, continuous CTA/cardiac function analysis (CFA), and CTA/CFA modulation. Accordingly, we clarified the CT dose index (CTDI) to determine the relationship between heart rate (HR) and X-ray exposure...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28275420/non-cardiovascular-computed-tomography-incidental-findings-in-patients-who-underwent-transaortic-valve-implantation-procedure
#3
Ahmed Fathala, Mnahi Bin Saeedan, Ali Zulfiqar, Hani Al Sergani
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a new treatment option for patients with severe aortic stenosis. Pre-TAVI procedure workup includes computed tomography angiography (CTA) of the heart and aorta from aortic annulus to the iliofemoral arteries. Frequently, there are a number of incidental non-cardiac findings (INCFs) in pre-TAVI CTA. However, the frequency and clinical significance of these INCFs are unknown. The aim of our study was to investigate the prevalence of INCFs and their clinical significance...
February 2017: Cardiology Research
https://www.readbyqxmd.com/read/28266929/fully-automatic-multi-atlas-segmentation-of-cta-for-partial-volume-correction-in-cardiac-spect-ct
#4
Qingyi Liu, Hassan Mohy-Ud-Din, Nabil Boutagy, Mingyan Jiang, Silin Ren, John Stendahl, Albert Sinusas, Chi Liu
Anatomical-based partial volume correction (PVC) has been shown to improve image quality and quantitative accuracy in cardiac SPECT/CT. However, this method requires manual segmentation of various organs from contrast-enhanced computed tomography angiography (CTA) data. In order to achieve fully automatic CTA segmentation for clinical translation, we investigated the most common multi-atlas segmentation methods. We also modified the multi-atlas segmentation method by introducing a novel label fusion algorithm for multiple organ segmentation to eliminate overlap and gap voxels...
March 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28252392/convnet-based-localization-of-anatomical-structures-in-3d-medical-images
#5
Bob de Vos, Jelmer Wolterink, Pim de Jong, Tim Leiner, Max Viergever, Ivana Isgum
Localization of anatomical structures is a prerequisite for many tasks in medical image analysis. We propose a method for automatic localization of one or more anatomical structures in 3D medical images through detection of their presence in 2D image slices using a convolutional neural network (ConvNet). A single ConvNet is trained to detect presence of the anatomical structure of interest in axial, coronal, and sagittal slices extracted from a 3D image. To allow the ConvNet to analyze slices of different sizes, spatial pyramid pooling is applied...
February 23, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28247763/n-n-dimethyl-tertiary-amino-group-mediated-dual-pancreas-and-lung-targeting-therapy-against-acute-pancreatitis
#6
Shi Luo, Peiwen Li, Sha Li, Zhengwu Du, Xun Hu, Yao Fu, Zhirong Zhang
Acute pancreatitis (AP) is a sudden inflammation of the pancreas with high-mortality rate worldwide. As a severe complication to AP, acute lung injury has been the major cause of death among patients with AP. Poor penetration across the blood pancreas barrier (BPB), and insufficient drug accumulation at the target site often result in poor therapeutic outcome. Our previous work successfully demonstrated a dual-specific targeting strategy to pancreas and lung using a phenolic propanediamine moiety. Inspired by this, a simplified ligand structure, N, N-dimethyl tertiary amino group, was covalently conjugated to celastrol (CLT) to afford tertiary amino conjugates via either an ester (CP) or an amide linkage (CTA)...
March 1, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28229912/mid-diastolic-left-ventricular-volume-and-mass-normal-values-for-coronary-computed-tomography-angiography
#7
Daniel Juneau, Fernanda Erthal, Owen Clarkin, Atif Alzahrani, Ali Alenazy, Alomgir Hossain, Joao R Inacio, Girish Dwivedi, Alexander J Dick, Frank J Rybicki, Benjamin J W Chow
BACKGROUND: The adoption of prospectively ECG-triggered acquisition coronary computed tomography angiography (CTA) has resulted in the inability to measure left ventricle (LV) end-diastolic volume and LV ejection fraction. However other prognostic measures such as LV mass and LV mid-diastolic volume (LVMDV) can still be assessed. The objective of this study is to establish normal reference values for LVMDV and LV mass. METHODS: Left ventricular mid-diastolic volumes and LV mass were prospectively measured in 2647 consecutive 'normal' patients undergoing prospectively ECG-triggered coronary CTA...
February 10, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28210769/preprocedural-risk-assessment-prior-to-ppvi-with-cmr-and-cardiac-ct
#8
Ladonna Malone, Brian Fonseca, Thomas Fagan, Jane Gralla, Neil Wilson, Micheal DiMaria, Uyen Truong, Lorna P Browne
Percutaneous pulmonary valve intervention (PPVI) is a less invasive and less costly approach to pulmonary valve replacement compared with the surgical alternative. Potential complications of PPVI include coronary compression and pulmonary arterial injury/rupture. The purpose of this study was to characterize the morphological risk factors for PPVI complication with cardiac MRI and cardiac CTA. A retrospective review of 88 PPVI procedures was performed. 44 patients had preprocedural cardiac MRIs or CTAs available for review...
February 16, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28185172/-18-f-fdg-pet-ct-angiography-for-the-diagnosis-of-infective-endocarditis
#9
REVIEW
A Roque, M N Pizzi, H Cuéllar-Calàbria, S Aguadé-Bruix
PURPOSE OF REVIEW: This article reviews the current imaging role of (18)F-fluordeoxyglucose positron emission computed tomography ((18)F-FDG-PET/CT) combined with cardiac CT angiography (CTA) in infective endocarditis and discusses the strengths and limitations of this technique. RECENT FINDINGS: The diagnosis of infective endocarditis affecting prosthetic valves and intracardiac devices is challenging because echocardiography and, therefore, the modified Duke criteria have well-recognized limitations in this clinical scenario...
February 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28126251/difference-of-coronary-stenosis-severity-between-systolic-and-diastolic-phases-in-quantitative-ct-angiography
#10
Hui Gu, Yang Gao, Haiping Wang, Zhennan Li, Liang Xu, Bo Xu, Ximing Wang, Bin Lu
BACKGROUND: To compare the difference of coronary diameter stenosis by quantitative analysis of CT angiography (QCT) in the systolic (QCT-S) and diastolic phase (QCT-D) of the cardiac cycle, with invasive catheter angiography (QCA) as reference standard. METHODS: A total of 109 patients (57.5 ± 10.6 years, 78.9% male) with suspected coronary artery disease (CAD) who underwent both CT angiography and invasive catheter angiography were retrospectively included in this study...
January 17, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28111212/global-quantification-of-left-ventricular-myocardial-perfusion-at-dynamic-ct-imaging-prognostic-value
#11
Felix G Meinel, Julian L Wichmann, U Joseph Schoepf, Francesca Pugliese, Ullrich Ebersberger, Gladys G Lo, Yeon Hyeon Choe, Yining Wang, Christian Tesche, Sabrina Segreto, Wolfgang G Kunz, Kolja M Thierfelder, Fabian Bamberg, Carlo N De Cecco
BACKGROUND: There is no published data on the prognostic value of global myocardial perfusion values at stress dynamic CT myocardial perfusion imaging (CTMPI). METHODS: Data of 144 patients from 6 centers who had undergone coronary CT angiography (coronary CTA) and CTMPI were assessed. Coronary CTA studies were acquired at rest; CTMPI was performed under vasodilator stress. Coronary CTA data were evaluated for coronary artery stenosis (≥50% luminal narrowing) on a per-vessel basis...
January 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28100426/ferumoxytol-mra-for-transcatheter-aortic-valve-replacement-planning-with-renal-insufficiency
#12
Kimberly Kallianos, Travis S Henry, Yerem Yeghiazarians, Jeffrey Zimmet, Kendrick A Shunk, Elaine E Tseng, Vaikom Mahadevan, Michael D Hope
BACKGROUND: Computed tomography angiography (CTA) is the test of choice for pre-procedure imaging of transcatheter aortic valve replacement (TAVR) candidates. The iodinated contrast required, however, increases the risk of renal dysfunction in patients with pre-existing renal failure. Ferumoxytol is a magnetic resonance imaging (MRI) contrast agent that can be used with renal failure. Its long vascular resonance time allows gated MRA sequences that approach CTA in image quality. We present respiratory and cardiac gated MRA enabled by ferumoxytol that can be post-processed in an analogous fashion to CTA...
March 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28057636/ct-angiography-of-the-head-in-extracorporeal-membrane-oxygenation
#13
J Acharya, A G Rajamohan, M R Skalski, M Law, W Gibbs
Extracorporeal membrane oxygenation is an artificial cardiopulmonary bypass technique used to support patients with severe pulmonary failure or both pulmonary and cardiac failure. The hemodynamic changes produced by extracorporeal membrane oxygenation affect the appearance of CTA of the head images, often confounding interpretation if the correct history and understanding of extracorporeal membrane oxygenation are not known. This technical report describes the principles of extracorporeal membrane oxygenation, techniques to optimize intracranial CTA imaging, and pitfalls...
January 5, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28048867/mo-ab-bra-10-super-high-temporal-resolution-cardiac-ct-imaging-using-smart-recon
#14
Y Li, X Cao, Z Xing, X Sun, J Hsieh, G Chen
PURPOSE: Coronary CT angiography is a challenging task currently limited by the achievable temporal resolution of modern MDCT scanners. In this work, a highly innovative method has been developed and validated to improve temporal resolution of the MDCT by a factor of four with the newly developed SMART-RECON method to enable high quality coronary CTA exams. The primary purpose of this paper is to investigate the relationships between: (1) SMART-RECON and the motion pattern; (2) SMART-RECON and the average speed of moving vessels; (3) SMART-RECON and the position and direction of moving vessels...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047154/su-f-t-405-development-of-a-rapid-cardiac-contouring-tool-using-landmark-driven-modeling
#15
C Pelletier, E Mosher, C Lee, C Lee, J Jung
PURPOSE: This study aims to develop a tool to rapidly delineate cardiac substructures for use in dosimetry for large-scale clinical trial or epidemiological investigations. The goal is to produce a system that can semi-automatically delineate nine cardiac structures to a reasonable accuracy within a couple of minutes. METHODS: The cardiac contouring tool employs a Most Similar Atlas method, where a selection criterion is used to pre-select the most similar model to the patient from a library of pre-defined atlases...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28027760/ct-angiography-for-planning-transcatheter-aortic-valve-replacement-using-automated-tube-voltage-selection-image-quality-and-radiation-exposure
#16
Stefanie Mangold, Carlo N De Cecco, U Joseph Schoepf, Taylor S Kuhlman, Akos Varga-Szemes, Damiano Caruso, Taylor M Duguay, Christian Tesche, Thomas J Vogl, Konstantin Nikolaou, Daniel H Steinberg, Julian L Wichmann
PURPOSE: To assess image quality and accuracy of CT angiography (CTA) for transcatheter aortic valve replacement (TAVR) planning performed with 3rd generation dual-source CT (DSCT). MATERIAL AND METHODS: We evaluated 125 patients who underwent TAVR-planning CTA on 3rd generation DSCT. A two-part protocol was performed including retrospectively ECG-gated coronary CTA (CCTA) and prospectively ECG-triggered aortoiliac CTA using 60mL of contrast medium. Automated tube voltage selection and advanced iterative reconstruction were applied...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28027746/image-quality-of-ct-angiography-using-model-based-iterative-reconstruction-in-infants-with-congenital-heart-disease-comparison-with-filtered-back-projection-and-hybrid-iterative-reconstruction
#17
COMPARATIVE STUDY
Qianjun Jia, Jian Zhuang, Jun Jiang, Jiahua Li, Meiping Huang, Changhong Liang
PURPOSE: To compare the image quality, rate of coronary artery visualization and diagnostic accuracy of 256-slice multi-detector computed tomography angiography (CTA) with prospective electrocardiographic (ECG) triggering at a tube voltage of 80kVp between 3 reconstruction algorithms (filtered back projection (FBP), hybrid iterative reconstruction (iDose(4)) and iterative model reconstruction (IMR)) in infants with congenital heart disease (CHD). METHODS: Fifty-one infants with CHD who underwent cardiac CTA in our institution between December 2014 and March 2015 were included...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28010914/reconstructions-using-rif-in-motion-mapping-technique-have-substantially-less-arrhythmogenic-artifacts-in-dual-source-coronary-cta
#18
Sebastian Daniel Reinartz, Markus Winkler, Sascha B Diefenbach, Thomas Allmendinger, Tobias Penzkofer, Christiane K Kuhl, Andreas H Mahnken
RATIONALE AND OBJECTIVES: Particularly for patients with heart arrhythmias, conventional BestSystole (BS) and BestDiastole (BD) reconstruction techniques in computed tomography (CT) frequently show artifacts that hinder the readability of the coronary tree. To address this problem, this paper presents an alternative reconstruction method that combines the technique "reconstructions with identical filling" (RIF) with motion mapping: This new technique is called "RIF in motion mapping" (RIMM)...
December 20, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27979575/the-right-atrium-and-tricuspid-annulus-are-cardinal-structures-in-tricuspid-regurgitation-with-or-without-pulmonary-hypertension
#19
Naohiko Nemoto, Jonathan G Schwartz, John R Lesser, Wesley D Pedersen, Paul Sorajja, Ross Garberich, Erin M Spinner, Robert S Schwartz
BACKGROUND: Right heart structural abnormalities occur in both tricuspid regurgitation (TR) and pulmonary hypertension (PH). They may occur independently or together, but their joint effects on cardiac structure are incompletely described. This study examined the interactions of TR severity and PH on right heart structural changes. METHODS: The study evaluated 455 patients undergoing both echocardiography and CT angiography (CTA). Cases were divided into 3 groups by TR severity: trace (n=217), mild (n=174), and significant (moderate or severe, n=64)...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27958693/ct-myocardial-perfusion-state-of-the-science
#20
Damiano Caruso, Domenico DE Santis, U Joseph Schoepf, Marta Zerunian, Marwen Eid, Akos Varga-Szemes, Christian Tesche, Taylor M Duguay, Andrea Laghi, Carlo N DE Cecco
Non-invasive cardiac imaging has rapidly evolved during the last decade due to advancements in CT technologies. Coronary CT angiography (CCTA) has been shown to reliably assess the coronary anatomy and has established itself as the non-invasive imaging technique with the highest sensitivity and specificity in the evaluation of patients with suspected coronary artery disease (CAD). However, this technique has previously been limited to a pure anatomical assessment. CT myocardial perfusion imaging (CT-MPI) is an increasingly rediscovered CT technique able to provide functional assessment of the myocardium and, when combined with CTA, allows for a comprehensive assessment of the coronary arteries, all done within a single modality...
December 13, 2016: Minerva Cardioangiologica
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