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Cardiac CTA

Yoriaki Matsumoto, Takanori Masuda, Yukari Yamashita, Takayuki Oku, Hirofumi Uyama, Tomoyasu Sato, Naoyuki Imada
PURPOSE: The purpose of this study was to investigate the association of vessel visibility and radiation dose using contrast-to-noise ratio (CNR) method with low tube voltage in coronary computed tomography angiography (c-CTA). METHODS: We performed electrocardiogram-gated scan of 2.0-mm diameter simulated vessel in the center of the cardiac phantom by the use of a 64-detector CT scanner. Reference CNR was calculated from the target coronary CT number (CTnumberA; 350 Hounsfield units [HU]), epicardial fat CT number (CTnumberB; -100 HU), and target epicardial fat standard deviation (SD) number (SDB; 25 HU) at the 120 kV...
2016: Nihon Hoshasen Gijutsu Gakkai Zasshi
J Tobias Kühl, Thomas S Kristensen, Anna F Thomsen, Louise Hindsø, Kristoffer L Hansen, Olav W Nielsen, Henning Kelbæk, Klaus F Kofoed
BACKGROUND: Signs of pulmonary congestion obtained from cardiac computed tomography angiographic (coronary CTA) images have not previously been related to clinical congestion or outcome and the clinical value is, therefore, unknown. Our objective was to test the hypothesis that signs of pulmonary congestion predict clinical heart failure and adverse outcome in patients with myocardial infarction. METHODS: Coronary CTA was performed before invasive treatment in 400 prospectively included patients with non ST segment elevation myocardial infarction in an observational study...
September 15, 2016: Journal of Cardiovascular Computed Tomography
Huanhuan Wang, Yin Zhang, Yanbo Xie, Hongyue Wang, Jinqing Yuan
INTRODUCTION: Coronary artery aneurysm (CAA) is defined as coronary dilatation which exceeds the diameter of the normal adjacent artery segments or the diameter of the patient's largest coronary artery by 1.5 times. The incidence of giant CAA is difficult to be determined, since only few reports have been described in the literature. METHODS AND RESULTS: A 65-year-old man was referred to our hospital because of a "mass" in the right heart detected on echocardiography at a regular medical health examination, while he experienced no any symptoms...
September 2016: Medicine (Baltimore)
Aimee E Moores, Michael S Cahill, Todd C Villines
Aortic mycotic aneurysms are a rare but life-threatening potential complication of infective endocarditis. Rapid deterioration of the vascular wall in highly focal areas makes these pseudoaneurysms particularly prone to rupture, resulting in uncontrolled aortic hemorrhage. While computed tomography angiography (CTA) is the imaging modality of choice for the evaluation of mycotic aneurysms, it is not routinely performed in patients with known or suspected infective endocarditis (IE). However, current valvular heart disease guidelines support the use of cardiac CTA in cases of IE and suspected perivalvular extension when there is inadequate or ambiguous visualization on echocardiography...
2016: Case Reports in Medicine
María N Pizzi, Albert Roque, Hug Cuéllar-Calabria, Nuria Fernández-Hidalgo, Ignacio Ferreira-González, María T González-Alujas, Alberto Igual-Barceló, David Garcia-Dorado, Benito Almirante, Joan Castell-Conesa, Manuel Escobar Amores, Pilar Tornos, Santiago Aguadé-Bruix
No abstract text is available yet for this article.
October 2016: JACC. Cardiovascular Imaging
Se Hun Kang, Gyung-Min Park, Seung-Whan Lee, Sung-Cheol Yun, Young-Hak Kim, Young-Rak Cho, Hyun Woo Park, Jon Suh, Dong Hyun Yang, Joon-Won Kang, Tae-Hwan Lim, Chang Hee Jung, Eun Hee Koh, Woo Je Lee, Min-Seon Kim, Ki-Up Lee, Joong-Yeol Park
OBJECTIVES: This study sought to evaluate the long-term prognostic value of coronary computed tomography angiography (CTA) in asymptomatic patients with type 2 diabetes mellitus. BACKGROUND: There are limited data on the long-term prognostic impact of coronary CTA in asymptomatic patients with type 2 diabetes mellitus. METHODS: This study analyzed clinical outcomes of 591 consecutive asymptomatic patients with type 2 diabetes mellitus who underwent coronary CTA (mean age 62...
September 9, 2016: JACC. Cardiovascular Imaging
Cas Teunissen, Jesse Habets, Birgitta K Velthuis, Maarten J Cramer, Peter Loh
Prior to atrial fibrillation (AF) ablation, computed tomography angiography (CTA) is increasingly used for left atrial appendage (LAA) thrombus detection. LAA filling defects on CTA may represent thrombus or incomplete contrast mixing with blood. A pre-bolus of contrast material with delay before the CTA contrast bolus can help distinguish between thrombus and incomplete contrast mixing. We present results from a double-contrast, single-phase CTA protocol used in our daily clinical practice. In patients who underwent AF ablation between 2011 and 2015, double-contrast, single-phase CTA was performed prior to ablation...
September 6, 2016: International Journal of Cardiovascular Imaging
Erin P Ward, Daniele Shiavazzi, Divya Sood, Allison Marsden, John Lane, Erik Owens, Andrew Barleben
BACKGROUND: Currently, the gold standard diagnostic examination for significant aortoiliac lesions is angiography. Fractional flow reserve (FFR) has a growing body of literature in coronary artery disease as a minimally invasive diagnostic procedure. Improvements in numerical hemodynamics have allowed for an accurate and minimally invasive approach to estimating FFR, utilizing cross-sectional imaging. We aim to demonstrate a similar approach to aortoiliac occlusive disease (AIOD). METHODS: A retrospective review evaluated 7 patients with claudication and cross-sectional imaging showing AIOD...
August 26, 2016: Annals of Vascular Surgery
Anna E Huis In 't Veld, Alexander G Van Vliet, Onno A Spruijt, M Louis Handoko, J Tim Marcus, Anton Vonk Noordegraaf, Harm-Jan Bogaard
BACKGROUND/OBJECTIVES: Assessing atrial sizes by routine non-gated CT-angiography (CTA) could be of value in discriminating between pulmonary hypertension (PH) due to heart failure with preserved ejection fraction (HFpEF) and idiopathic pulmonary arterial hypertension (IPAH). We aimed to determine how left (LA) and right atrial (RA) sizes on non-gated CTA can help discriminate between these patients. METHODS AND RESULTS: In an initial study, CMR was used in 15 IPAH and 15 PH-HFpEF patients to determine LA- and RA size throughout the cardiac cycle...
November 15, 2016: International Journal of Cardiology
Sharon Steinberger, Andrew J Plodkowski, Larry Latson, Jeffrey M Levsky, Benjamin Zalta, Alla Godelman, Hillel W Cohen, Linda B Haramati
OBJECTIVE: To assess the incidence and cause of discrepancies between coronary computed tomography angiography (CTA) and catheterization in a high-risk, diverse, predominantly overweight inner-city population. METHODS: Ninety-two patients who underwent coronary CTA and catheterization on March 2007 to December 2012 were retrospectively identified. Clinical coronary CTA interpretation and reinterpretation by a review panel was compared with catheterization results...
August 25, 2016: Journal of Computer Assisted Tomography
Lloyd M Felmly, Carlo N De Cecco, U Joseph Schoepf, Akos Varga-Szemes, Stefanie Mangold, Andrew D McQuiston, Sheldon E Litwin, Richard R Bayer, Thomas J Vogl, Julian L Wichmann
PURPOSE: To investigate feasibility, image quality and safety of low-tube-voltage, low-contrast-volume comprehensive cardiac and aortoiliac CT angiography (CTA) for planning transcatheter aortic valve replacement (TAVR). MATERIALS AND METHODS: Forty consecutive TAVR candidates prospectively underwent combined CTA of the aortic root and vascular access route (270 mgI/ml iodixanol). Patients were assigned to group A (second-generation dual-source CT [DSCT], 100 kV, 60 ml contrast, 4...
August 23, 2016: European Radiology
Yuki Tanabe, Teruhito Kido, Akira Kurata, Shun Sawada, Hiroshi Suekuni, Tomoyuki Kido, Takahiro Yokoi, Teruyoshi Uetani, Katsuji Inoue, Masao Miyagawa, Teruhito Mochizuki
OBJECTIVES: To evaluate the feasibility of three-dimensional (3D) maximum principal strain (MP-strain) derived from cardiac computed tomography (CT) for detecting myocardial infarction (MI). METHODS: Forty-three patients who underwent cardiac CT and magnetic resonance imaging (MRI) were retrospectively selected. Using the voxel tracking of motion coherence algorithm, the peak CT MP-strain was measured using the 16-segment model. With the trans-mural extent of late gadolinium enhancement (LGE) and the distance from MI, all segments were classified into four groups (infarcted, border, adjacent, and remote segments); infarcted and border segments were defined as MI with LGE positive...
August 19, 2016: European Radiology
Christian Tesche, Fabian Plank, Carlo N De Cecco, Taylor M Duguay, Moritz H Albrecht, Akos Varga-Szemes, Richard R Bayer, Junjie Yang, Isaac L Jacks, Bettina M Gramer, Ullrich Ebersberger, Ellen Hoffmann, Salvatore A Chiaramida, Gudrun Feuchtner, U Joseph Schoepf
OBJECTIVE: To evaluate quantitative markers derived from coronary CT angiography (coronary CTA) for the prediction of major adverse cardiac events (MACE). MATERIALS AND METHODS: Pooled data from two centers in the US and Europe were retrospectively analyzed. Forty-six patients (65.5 ± 8.1 years, 62% male) with suspected coronary artery disease (CAD) who had undergone dual-source CCTA and had experienced MACE within 12 months were included and compared to a Framingham risk score matched cohort (n = 46) without MACE...
August 5, 2016: Journal of Cardiovascular Computed Tomography
James Nadel, Eoin O'Dwyer, Sam Emmanuel, Justyn Huang, Sarat Cheruvu, Neville Sammel, Bruce Brew, James Otton, Cameron J Holloway
BACKGROUND: Human immunodeficiency virus (HIV) infection is considered a chronic, treatable disease, although treatment is associated with increased rates of coronary artery disease (CAD). We analyzed the utility of coronary CTA in the assessment of CAD among HIV patients and explored whether HIV patients are at greater risk of associated morbidity and mortality compared to HIV-negative controls. METHODS: In a retrospective, single center cohort study 97 males without history of previous coronary artery disease who had undergone coronary CTA between 2011 and 2014 was analyzed, including 32 HIV positive patients and 65 matched HIV negative controls...
September 2016: Journal of Cardiovascular Computed Tomography
Damiano Caruso, Marwen Eid, U Joseph Schoepf, Kwang Nam Jin, Akos Varga-Szemes, Christian Tesche, Stefanie Mangold, Adam Spandorfer, Andrea Laghi, Carlo N De Cecco
Non-invasive cardiac imaging has rapidly evolved during the last decade due to advancements in CT based technologies. Coronary CT angiography has been shown to reliably assess coronary anatomy and detect high risk coronary artery disease. However, this technique is limited to anatomical assessment, thus non-invasive techniques for functional assessment of the heart are necessary. CT myocardial perfusion is a new CT based technique that provides functional assessment of the myocardium and allows for a comprehensive assessment of coronary artery disease with a single modality when combined with CTA...
October 2016: European Journal of Radiology
Gudrun Feuchtner, Johannes Kerber, Philipp Burghard, Wolfgang Dichtl, Guy Friedrich, Nikolaos Bonaros, Fabian Plank
AIMS: To assess the prognostic value of coronary CT angiography (CTA) for prediction of major adverse cardiac events (MACE) over a long-term follow-up period. METHODS AND RESULTS: A total of 1469 low-to-intermediate-risk patients (65.9 years; 44.2% females) were included in our prospective cohort study. CTA was evaluated for (i) stenosis severity (minimal <10%; mild <50%; moderate 50-70%; severe >70%), (ii) plaque types (calcified, mixed dominantly calcified, mixed dominantly non-calcified, non-calcified), and (iii) high-risk plaque criteria [low-attenuation plaque (LAP) quantified by HU, napkin-ring (NR) sign, spotty calcification <3 mm, and remodelling index (RI)]...
August 7, 2016: European Heart Journal Cardiovascular Imaging
Omar K Khalique, Todd C Pulerwitz, Sandra S Halliburton, Susheel K Kodali, Rebecca T Hahn, Tamim M Nazif, Torsten P Vahl, Isaac George, Martin B Leon, Belinda D'Souza, Andrew J Einstein
Transcatheter aortic valve replacement (TAVR) is performed frequently in patients with severe, symptomatic aortic stenosis who are at high risk or inoperable for open surgical aortic valve replacement. Computed tomography angiography (CTA) has become the gold standard imaging modality for pre-TAVR cardiac anatomic and vascular access assessment. Traditionally, cardiac CTA has been most frequently used for assessment of coronary artery stenosis, and scanning protocols have generally been tailored for this purpose...
September 2016: Journal of Cardiovascular Computed Tomography
Pamela S Douglas, Bernard De Bruyne, Gianluca Pontone, Manesh R Patel, Bjarne L Norgaard, Robert A Byrne, Nick Curzen, Ian Purcell, Matthias Gutberlet, Gilles Rioufol, Ulrich Hink, Herwig Walter Schuchlenz, Gudrun Feuchtner, Martine Gilard, Daniele Andreini, Jesper M Jensen, Martin Hadamitzky, Karen Chiswell, Derek Cyr, Alan Wilk, Furong Wang, Campbell Rogers, Mark A Hlatky
BACKGROUND: Coronary computed tomographic angiography (CTA) plus estimation of fractional flow reserve using CTA (FFRCT) safely and effectively guides initial care over 90 days in patients with stable chest pain. Longer-term outcomes are unknown. OBJECTIVES: The study sought to determine the 1-year clinical, economic, and quality-of-life (QOL) outcomes of using FFRCT instead of usual care. METHODS: Consecutive patients with stable, new onset chest pain were managed by either usual testing (n = 287) or CTA (n = 297) with selective FFRCT (submitted in 201, analyzed in 177); 581 of 584 (99...
August 2, 2016: Journal of the American College of Cardiology
Masanao Kobayashi, Yasuki Asada, Kosuke Matsubara, Shouichi Suzuki, Kichiro Koshida, Yuta Matsunaga, Tomonobu Haba, Ai Kawaguchi, Hiroshi Toyama, Ryouichi Kato
The primary study objective was to assess radiation doses using a modified form of the Imaging Performance Assessment of Computed Tomography (CT) scanner (ImPACT) patient dosimetry for cardiac applications on an Aquilion ONE ViSION Edition scanner, including the Ca score, target computed tomography angiography (CTA), prospective CTA, continuous CTA/cardiac function analysis (CFA), and CTA/CFA modulation. Accordingly, we clarified the CT dose index (CTDI) to determine the relationship between heart rate (HR) and X-ray exposure...
2016: Journal of Applied Clinical Medical Physics
Masayuki Kawabe, Akira Sato, Tomoya Hoshi, Masae Endo, Ikuo Yoshida, Kazutaka Aonuma
BACKGROUND: B-type natriuretic peptide (BNP) is well known to increase as a result of left ventricular systolic dysfunction and is a useful diagnostic marker for heart failure. The purpose of this study was to assess the incremental value of BNP for predicting obstructive coronary artery disease (CAD) on computed tomography angiography (CTA) in patients with suspected CAD. METHODS: This was an observational analysis of patients with stable CAD undergoing CTA in our institution between April 2008 and June 2014...
July 18, 2016: Journal of Cardiology
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