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Cardiac CTA

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https://www.readbyqxmd.com/read/28416358/non-gated-high-pitch-computed-tomography-aortic-angiography-myocardial-perfusion-defects-in-patients-with-suspected-aortic-dissection
#1
Li-Ting Huang, Shih-Hung Chan, Chia-Chang Chuang, Yi-Shan Tsai
OBJECTIVES: To investigate the diagnostic value of first-pass myocardial perfusion defects visualised in non-gated high-pitch computed tomography angiography (CTA) in patients admitted to the emergency department (ED) for suspected aortic dissection. METHODS: We recruited 174 ED patients who underwent high-pitch CTA of the aorta because of suspected aortic dissection. We divided these patients into two groups (diseased and control groups) based on whether their clinical data fulfilled the third universal definition of acute myocardial infarction (AMI), specifically an increase in cardiac troponin (cTn) with at least one of the following: (a) symptoms of ischemia; (b) new ST-segment-T wave (ST-T) changes or new left bundle branch block (LBBB); (c) development of pathological Q wave; (d) new loss of viable myocardium or new regional wall motion abnormality; or (e) identification of an intracoronary thrombus by angiography or autopsy...
April 12, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28412436/noninvasive-ffr-derived-from-coronary-ct-angiography-management-and-outcomes-in-the-promise-trial
#2
Michael T Lu, Maros Ferencik, Rhonda S Roberts, Kerry L Lee, Alexander Ivanov, Elizabeth Adami, Daniel B Mark, Farouc A Jaffer, Jonathon A Leipsic, Pamela S Douglas, Udo Hoffmann
OBJECTIVES: The purpose of this study was to determine whether noninvasive fractional flow reserve derived from computed tomography (FFRCT) predicts coronary revascularization and outcomes and whether its addition improves efficiency of referral to invasive coronary angiography (ICA) after coronary computed tomography angiography (CTA). BACKGROUND: FFRCT may improve the efficiency of an anatomic CTA strategy for stable chest pain. METHODS: This observational cohort study included patients with stable chest pain in the PROMISE trial (PROspective Multicenter Imaging Study for Evaluation of Chest Pain) referred to ICA within 90 days after CTA...
April 7, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28409258/impact-of-knowledge-based-iterative-model-reconstruction-on-myocardial-late-iodine-enhancement-in-computed-tomography-and-comparison-with-cardiac-magnetic-resonance
#3
Yuki Tanabe, Teruhito Kido, Akira Kurata, Naoki Fukuyama, Takahiro Yokoi, Tomoyuki Kido, Teruyoshi Uetani, Mani Vembar, Amar Dhanantwari, Shinichi Tokuyasu, Natsumi Yamashita, Teruhito Mochizuki
We evaluated the image quality and diagnostic performance of late iodine enhancement computed tomography (LIE-CT) with knowledge-based iterative model reconstruction (IMR) for the detection of myocardial infarction (MI) in comparison with late gadolinium enhancement magnetic resonance imaging (LGE-MRI). The study investigated 35 patients who underwent a comprehensive cardiac CT protocol and LGE-MRI for the assessment of coronary artery disease. The CT protocol consisted of stress dynamic myocardial CT perfusion, coronary CT angiography (CTA) and LIE-CT using 256-slice CT...
April 13, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28408704/changing-use-patterns-for-99m-tc-maa-from-2000-to-2015
#4
James A Ponto
Since the early 2000's, evaluation of pulmonary embolism (PE) has shifted from (99m)Tc macroaggregated albumin (MAA) perfusion lung scans to CT angiography (CTA). (99m)Tc MAA continues to be used in patients with contraindications to CTA and for other uses. A reduced number of MAA particles is used in patients with pulmonary hypertension (PH) or other risk factors. This study assessed the changing use patterns for (99m)Tc MAA by comparing snap-shots of procedures in 2000 and in 2015 in one institution. Methods: Records for all patients receiving (99m)Tc MAA in the year 2000 and in 2015 were reviewed, making note of the imaging procedure, any contraindication to CTA, and if a reduced number of MAA particles was used...
April 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28394783/cardiac-computed-tomography-for-planning-revascularization-procedures
#5
Maksymilian P Opolski
Coronary computed tomography angiography (coronary CTA) is being increasingly used to detect and rule out coronary artery stenoses. Beyond stenosis detection, the abundance of anatomic, morphologic, and physiological information incorporated from a single one-stop-shop CT study has generated considerable interest in the context of preprocedural planning for coronary revascularization. Specifically, preprocedural CTA data sets can assist interventional cardiologists with selective catheter placement, appropriate guidewire choice, accurate stent size selection, and, most importantly, development of a stepwise revascularization strategy plan...
April 7, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28385304/functional-testing-or-coronary-computed-tomography-angiography-in-patients-with-stable%C3%A2-coronary-artery-disease
#6
Mads E Jørgensen, Charlotte Andersson, Bjarne L Nørgaard, Jawdat Abdulla, Jacqueline B Shreibati, Christian Torp-Pedersen, Gunnar H Gislason, Richard E Shaw, Mark A Hlatky
BACKGROUND: The choice of either anatomical or functional noninvasive testing to evaluate suspected coronary artery disease might affect subsequent clinical management and outcomes. OBJECTIVES: This study analyzed the association of initial noninvasive cardiac testing in outpatients with stable symptoms, with subsequent use of medications, invasive procedures, and clinical outcomes. METHODS: We studied patients enrolled in a Danish nationwide register who underwent initial noninvasive cardiac testing with either coronary computed tomography angiography (CTA) or functional testing (exercise electrocardiography or nuclear stress testing) from 2009 to 2015...
April 11, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28374180/coronary-artery-anomalies-when-you-need-to-worry
#7
REVIEW
Ajar Kochar, Todd Kiefer
PURPOSE OF REVIEW: There is a broad spectrum of coronary artery anomalies that cardiologists may encounter either incidentally or during evaluation for cardiac symptoms. These anomalies include anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS), coronary fistulae, and coronary artery aneurysms. This manuscript outlines the unique features, diagnostic characteristics, and treatment considerations for these lesions. RECENT FINDINGS: Intravenous ultrasound (IVUS), computed tomographic angiography (CTA), and magnetic resonance imaging (MRI) are becoming more sophisticated and will be increasingly used to facilitate the optimal treatment approach for coronary anomalies...
May 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28373781/the-prevalence-of-coronary-artery-anomalies-in-qassim-province-detected-by-cardiac-computed-tomography-angiography
#8
Osama A Smettei, Sawsan Sayed, Rami M Abazid
BACKGROUND: Coronary artery anomalies (CAAs) affect about 1% of the general population based on invasive coronary angiography (ICA) data, computed tomography angiography (CTA) enables better visualization of the origin, course, relation to the adjacent structures, and termination of CAAs compared to ICA. OBJECTIVE: The aim of our work is to estimate the frequency of CAAs in Qassim province among patients underwent cardiac CTA at Prince Sultan Cardiac Center. METHODS: Retrospective analysis of the CTA data of 2235 patients between 2009 and 2015...
April 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28369397/significant-survival-advantage-of-high-pulmonary-vein-index-and-the-presence-of-native-pulmonary-artery-in-pulmonary-atresia-with-ventricular-septal-defect-and-major-aortopulmonary-collateral-arteries-results-from-preoperative-computed-tomography-angiography
#9
Qianjun Jia, Jianzheng Cen, Jian Zhuang, Xiaomei Zhong, Xiaoqing Liu, Jiahua Li, Changhong Liang, Meiping Huang
OBJECTIVES: The prognosis of pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries (PA-VSD-MAPCAs) after surgery shows substantial clinical heterogeneity and predictors for outcomes are lacking. This study aimed to assess the predictive value of preoperative cardiac computed tomography angiography (CTA) for survival in patients with PA-VSD-MAPCAs. METHODS: We retrospectively analysed PA-VSD-MAPCA patients with preoperative CTA who underwent both right ventricular outflow tract reconstruction and MAPCA unifocalization ( n  = 24) or pulmonary artery rehabilitation ( n  = 28)...
March 28, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28314613/improved-image-quality-with-simultaneously-reduced-radiation-exposure-knowledge-based-iterative-model-reconstruction-algorithms-for-coronary-ct-angiography-in-a-clinical-setting
#10
Florian André, Philipp Fortner, Mani Vembar, Dirk Mueller, Wolfram Stiller, Sebastian J Buss, Hans-Ulrich Kauczor, Hugo A Katus, Grigorios Korosoglou
BACKGROUND: The aim of this study was to assess the potential for radiation dose reduction using knowledge-based iterative model reconstruction (K-IMR) algorithms in combination with ultra-low dose body mass index (BMI)-adapted protocols in coronary CT angiography (coronary CTA). METHODS: Forty patients undergoing clinically indicated coronary CTA were randomly assigned to two groups with BMI-adapted (I: <25.0 kg/m(2), II: <28.0 kg/m(2), III: <30.0 kg/m(2), IV: ≥30...
February 23, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28296294/electrocardiogram-gated-coronary-ct-angiography-dose-estimates-using-impact
#11
Masanao Kobayashi, Yasuki Asada, Kosuke Matsubara, Shouichi Suzuki, Kichiro Koshida, Yuta Matsunaga, Tomonobu Haba, Ai Kawaguchi, Hiroshi Toyama, Ryoichi Kato
The primary study objective was to assess radiation doses using a modified form of the Imaging Performance Assessment of Computed Tomography (CT) scanner (ImPACT) patient dosimetry for cardiac applications on an Aquilion ONE ViSION Edition scanner, including the Ca score, target computed tomography angiography (CTA), prospective CTA, continuous CTA/cardiac function analysis (CFA), and CTA/CFA modulation. Accordingly, we clarified the CT dose index (CTDI) to determine the relationship between heart rate (HR) and X-ray exposure...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28275420/non-cardiovascular-computed-tomography-incidental-findings-in-patients-who-underwent-transaortic-valve-implantation-procedure
#12
Ahmed Fathala, Mnahi Bin Saeedan, Ali Zulfiqar, Hani Al Sergani
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a new treatment option for patients with severe aortic stenosis. Pre-TAVI procedure workup includes computed tomography angiography (CTA) of the heart and aorta from aortic annulus to the iliofemoral arteries. Frequently, there are a number of incidental non-cardiac findings (INCFs) in pre-TAVI CTA. However, the frequency and clinical significance of these INCFs are unknown. The aim of our study was to investigate the prevalence of INCFs and their clinical significance...
February 2017: Cardiology Research
https://www.readbyqxmd.com/read/28266929/fully-automatic-multi-atlas-segmentation-of-cta-for-partial-volume-correction-in-cardiac-spect-ct
#13
Qingyi Liu, Hassan Mohy-Ud-Din, Nabil E Boutagy, Mingyan Jiang, Silin Ren, John C Stendahl, Albert J Sinusas, Chi Liu
Anatomical-based partial volume correction (PVC) has been shown to improve image quality and quantitative accuracy in cardiac SPECT/CT. However, this method requires manual segmentation of various organs from contrast-enhanced computed tomography angiography (CTA) data. In order to achieve fully automatic CTA segmentation for clinical translation, we investigated the most common multi-atlas segmentation methods. We also modified the multi-atlas segmentation method by introducing a novel label fusion algorithm for multiple organ segmentation to eliminate overlap and gap voxels...
March 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28252392/convnet-based-localization-of-anatomical-structures-in-3d-medical-images
#14
Bob de Vos, Jelmer Wolterink, Pim de Jong, Tim Leiner, Max Viergever, Ivana Isgum
Localization of anatomical structures is a prerequisite for many tasks in medical image analysis. We propose a method for automatic localization of one or more anatomical structures in 3D medical images through detection of their presence in 2D image slices using a convolutional neural network (ConvNet). A single ConvNet is trained to detect presence of the anatomical structure of interest in axial, coronal, and sagittal slices extracted from a 3D image. To allow the ConvNet to analyze slices of different sizes, spatial pyramid pooling is applied...
February 23, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28247763/n-n-dimethyl-tertiary-amino-group-mediated-dual-pancreas-and-lung-targeting-therapy-against-acute-pancreatitis
#15
Shi Luo, Peiwen Li, Sha Li, Zhengwu Du, Xun Hu, Yao Fu, Zhirong Zhang
Acute pancreatitis (AP) is a sudden inflammation of the pancreas with high mortality rate worldwide. As a severe complication to AP, acute lung injury has been the major cause of death among patients with AP. Poor penetration across the blood pancreas barrier (BPB) and insufficient drug accumulation at the target site often result in poor therapeutic outcome. Our previous work successfully demonstrated a dual-specific targeting strategy to pancreas and lung using a phenolic propanediamine moiety. Inspired by this, a simplified ligand structure, N,N-dimethyl tertiary amino group, was covalently conjugated to celastrol (CLT) to afford tertiary amino conjugates via either an ester (CP) or an amide linkage (CTA)...
March 27, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28229912/mid-diastolic-left-ventricular-volume-and-mass-normal-values-for-coronary-computed-tomography-angiography
#16
Daniel Juneau, Fernanda Erthal, Owen Clarkin, Atif Alzahrani, Ali Alenazy, Alomgir Hossain, Joao R Inacio, Girish Dwivedi, Alexander J Dick, Frank J Rybicki, Benjamin J W Chow
BACKGROUND: The adoption of prospectively ECG-triggered acquisition coronary computed tomography angiography (CTA) has resulted in the inability to measure left ventricle (LV) end-diastolic volume and LV ejection fraction. However other prognostic measures such as LV mass and LV mid-diastolic volume (LVMDV) can still be assessed. The objective of this study is to establish normal reference values for LVMDV and LV mass. METHODS: Left ventricular mid-diastolic volumes and LV mass were prospectively measured in 2647 consecutive 'normal' patients undergoing prospectively ECG-triggered coronary CTA...
February 10, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28210769/preprocedural-risk-assessment-prior-to-ppvi-with-cmr-and-cardiac-ct
#17
Ladonna Malone, Brian Fonseca, Thomas Fagan, Jane Gralla, Neil Wilson, Micheal DiMaria, Uyen Truong, Lorna P Browne
Percutaneous pulmonary valve intervention (PPVI) is a less invasive and less costly approach to pulmonary valve replacement compared with the surgical alternative. Potential complications of PPVI include coronary compression and pulmonary arterial injury/rupture. The purpose of this study was to characterize the morphological risk factors for PPVI complication with cardiac MRI and cardiac CTA. A retrospective review of 88 PPVI procedures was performed. 44 patients had preprocedural cardiac MRIs or CTAs available for review...
February 16, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28185172/-18-f-fdg-pet-ct-angiography-for-the-diagnosis-of-infective-endocarditis
#18
REVIEW
A Roque, M N Pizzi, H Cuéllar-Calàbria, S Aguadé-Bruix
PURPOSE OF REVIEW: This article reviews the current imaging role of (18)F-fluordeoxyglucose positron emission computed tomography ((18)F-FDG-PET/CT) combined with cardiac CT angiography (CTA) in infective endocarditis and discusses the strengths and limitations of this technique. RECENT FINDINGS: The diagnosis of infective endocarditis affecting prosthetic valves and intracardiac devices is challenging because echocardiography and, therefore, the modified Duke criteria have well-recognized limitations in this clinical scenario...
February 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28126251/difference-of-coronary-stenosis-severity-between-systolic-and-diastolic-phases-in-quantitative-ct-angiography
#19
Hui Gu, Yang Gao, Haiping Wang, Zhennan Li, Liang Xu, Bo Xu, Ximing Wang, Bin Lu
BACKGROUND: To compare the difference of coronary diameter stenosis by quantitative analysis of CT angiography (QCT) in the systolic (QCT-S) and diastolic phase (QCT-D) of the cardiac cycle, with invasive catheter angiography (QCA) as reference standard. METHODS: A total of 109 patients (57.5 ± 10.6 years, 78.9% male) with suspected coronary artery disease (CAD) who underwent both CT angiography and invasive catheter angiography were retrospectively included in this study...
January 17, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28111212/global-quantification-of-left-ventricular-myocardial-perfusion-at-dynamic-ct-imaging-prognostic-value
#20
Felix G Meinel, Julian L Wichmann, U Joseph Schoepf, Francesca Pugliese, Ullrich Ebersberger, Gladys G Lo, Yeon Hyeon Choe, Yining Wang, Christian Tesche, Sabrina Segreto, Wolfgang G Kunz, Kolja M Thierfelder, Fabian Bamberg, Carlo N De Cecco
BACKGROUND: There is no published data on the prognostic value of global myocardial perfusion values at stress dynamic CT myocardial perfusion imaging (CTMPI). METHODS: Data of 144 patients from 6 centers who had undergone coronary CT angiography (coronary CTA) and CTMPI were assessed. Coronary CTA studies were acquired at rest; CTMPI was performed under vasodilator stress. Coronary CTA data were evaluated for coronary artery stenosis (≥50% luminal narrowing) on a per-vessel basis...
January 2017: Journal of Cardiovascular Computed Tomography
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