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M Vujović, E Garalejic, B Arsic, M Zamurovic, M Perovic
BACKGROUND: The objective of the present paper is to confirm the validity and reliability of hysterosalpingography (HSG) in intrauterine pathology research of infertile female patients by comparing the hysteroscopy (HC) findings to a "gold standard" test. AIM: To analyze HSG and HC findings in infertility patients. MATERIALS AND METHODS: The research was conducted as a prospective study at the Gynecological and Obstetrics Clinic "Narodni front" in Belgrade...
2015: Clinical and Experimental Obstetrics & Gynecology
Ashley R Gilman Barber, Stephanie A Rhone, Margo R Fluker
OBJECTIVE: To investigate the noted cluster of cases of Asherman's syndrome in an 18-month period at an Early Pregnancy Assessment Centre at a tertiary care institution. METHODS: A practice audit was performed involving (a) a detailed chart review of the six index cases; and (b) compilation of treatment choices for all new patient referrals in the same 18-month time frame from July 2011 to December 2012. Diagnosis of Asherman's syndrome was made with a combination of clinical menstrual symptoms and hysteroscopic diagnosis of intrauterine adhesions...
November 2014: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
I Trifonov, J Uzunova
Herlyn-Werner-Wunderlich Syndrome results in a doubling of the internal genitalia accompanied by unilateral gynatresia (with hemi-hematokolpos, hemi-hematometra and/or hemi-hematosalpings) and ipsilateral renal agenesis. The authors considered the case of a successful full-term pregnancy in one uterus after pregnancy failure in the other imposed surgical removal of the same.
2014: Akusherstvo i Ginekologii︠a︡
Kuan-Hao Tsui, Li-Te Lin, Jiin-Tsuey Cheng, Sen-Wen Teng, Peng-Hui Wang
OBJECTIVE: Many preoperative, intraoperative, and postoperative methods have been described that improve the outcomes of women with severe Asherman syndrome, and it is likely that an integrated application of all of these methods may provide better reproductive outcomes; however, there is as yet no report on this type of integrated approach. MATERIALS AND METHODS: The cases of four infertile women with severe Asherman syndrome were analyzed retrospectively. The comprehensive therapeutic plan for the four women included (1) preoperative office hysteroscopy to confirm the diagnosis and evaluate the severity of disease; (2) the use of ultrasound-guided intraoperative abdominal procedures during the surgical procedure, including hysteroscopic adhesiolysis to ensure the entire the hysteroscopic dissection, and placement of a Hyalobarrier(®) gel and an intrauterine balloon catheter at the end of the surgery; (3) postoperative oral estrogen supplementation to enhance endometrial proliferation, removal of the balloon catheter, and a second-look office hysteroscopy; and (4) in vitro fertilization and embryo transfer (IVF & ET) for three of the four patients...
September 2014: Taiwanese Journal of Obstetrics & Gynecology
Moshe D Fejgin, Tal Y Shvit, Yael Gershtansky, Tal Biron-Shental
BACKGROUND: Removal of retained placental tissue postpartum and retained products of conception (RPOC) abortion is done by uterine curettage or hysteroscopy. Trauma to the endometrium from surgical procedures, primarily curettage, can cause intrauterine adhesions (Asherman's syndrome) and subsequent infertility. The incidence of malpractice claims relating to intrauterine adhesions is rising, justifying reevaluation of the optimal way of handling these complications. OBJECTIVES: To review malpractice claims regarding intrauterine adhesions, and to explore the clinical approach that might reduce those claims or improve their medical and legal outcomes...
August 2014: Israel Medical Association Journal: IMAJ
Ivan Mazzon, Alessandro Favilli, Mario Grasso, Stefano Horvath, Vittorio Bini, Gian Carlo Di Renzo, Sandro Gerli
OBJECTIVE: To study which variables are able to influence women's experience of pain during diagnostic hysteroscopy. DESIGN: Multivariate analysis (phase II) after a randomized, controlled trial (phase I). SETTING: Endoscopic gynecologic center. PATIENT(S): In phase I, 392 patients were analyzed. Group A: 197 women with carbon dioxide (CO2); group B: 195 women with normal saline. In phase II, 392 patients were assigned to two different groups according to their pain experience as measured by a visual analogue scale (VAS): group VAS>3 (170 patients); group VAS≤3 (222 patients)...
November 2014: Fertility and Sterility
Sevtap Kilic, Beril Yuksel, F Pinarli, A Albayrak, B Boztok, T Delibasi
PURPOSE: We evaluate the effect of stem cells to induce endometrial proliferation and angiogenesis on Asherman Syndrome (AS). METHODS: The experimental study was performed in stemcell research laboratory. Forty Wistar-Albino rats were divided according to groups. In group1 (n = 10) to establish the model; trichloroacetic acid was injected to right uterine horn. Two weeks later, intrauterine synechia was confirmed. In group2 (n = 10), 2 weeks later, 2 × 106 mesenchymal stem cells (MSC) were injected into right uterine horn followed by three intraperitoneal injections of MSCs...
August 2014: Journal of Assisted Reproduction and Genetics
Margaret Harpham, Jason Abbott
Uterine curettage may result in formation of intrauterine adhesions, which can predispose to recurrent miscarriage [1]. Herein is presented a video case report of a 24-year-old woman with recurrent miscarriages and recurrent intrauterine adhesions after treatment of non-progressive pregnancies. Targeted intrauterine pregnancy tissue removal using a hysteroscopic morcellator was performed to reduce the risk of adhesion recurrence. Successful removal of products of conception, without subsequent adhesion formation, and an ongoing viable pregnancy followed...
November 2014: Journal of Minimally Invasive Gynecology
Dongmei Song, Yuhuan Liu, Yu Xiao, Tin-Chiu Li, Fengqiong Zhou, Enlan Xia
STUDY OBJECTIVE: To compare the outcome of hysteroscopic adhesiolysis in women who had Asherman's syndrome after uterine artery embolization (UAE) with those who had Asherman's syndrome caused by surgical trauma. DESIGN: A retrospective cohort study matched for age and intrauterine adhesion score (Canadian Task Force classification II-2). SETTING: A tertiary hysteroscopic center in a teaching hospital. PATIENTS: Nineteen women with Asherman's syndrome after UAE and 57 women with Asherman's syndrome caused by surgical trauma...
November 2014: Journal of Minimally Invasive Gynecology
Feryal Alawadhi, Hongling Du, Hakan Cakmak, Hugh S Taylor
Asherman's Syndrome is characterized by intrauterine adhesions or fibrosis resulting as a consequence of damage to the basal layer of endometrium and is associated with infertility due to loss of normal endometrium. We have previously shown that bone marrow derived stem cells (BMDSCs) engraft the endometrium in mice and humans and Ischemia/reperfusion injury of uterus promoted BMDSCs migration to the endometrium; however, the role of BMDSCs in Asherman's syndrome has not been characterized. Here a murine model of Asherman's syndrome was created by traumatizing the uterus...
2014: PloS One
Shipra Kunwar, Tamkin Khan, Hemprabha Gupta
Vaginal stenosis (gynatresia) is commonly congenital, occurring as a part of Mayer-Kustner-Hauser syndrome. Those occurring postabortal or postpartum are rarely seen nowadays. Here, we report two cases, one in which there was complete stenosis postpartum following a retained gauze and another case, with chemical vaginal burns following attempted abortion by a local untrained midwife.
2014: BMJ Case Reports
R Pulcinella, L Giannone, E Candelori, E Giannone, F Patacchiola
AIM: The aim of the study was to evaluate the clinical usefulness of the selective removal of residual intrauterine trophoblastic tissue by using a hysteroscopic procedure, especially in the prevention of the Intra-Uterine Adhesion's Syndrome. METHODS: Seventy-six patients had an Asherman's Syndrome: 5 cases after laparotomic myomectomy, 1 after caesarean section, 2 after hysteroscopic myomectomy, 10 after VIP, 1 with a severe vaginal endometriosis, 1 after conisation, 4 after a post-partum hemorrhage due to coagulopathy or uterine atony, 20 cases after D&C because of PPH due to placental retention, 26 after repetitive D&Cs because of AUB due to post abortion chorial residues' retention, 6 cases after D&C for post menopausal AUB...
February 2014: Minerva Ginecologica
Dimitrios Papoutsis, Dimitrios Georgantzis, Maria Diletta Daccò, Gabor Halmos, Mohsen Moustafa, Ana Rita Mesquita Pinto, Adam Magos
AIMS: To present a study on severe Asherman's syndrome after open myomectomy and investigate the possible reasons for this outcome. METHODS: This study involves a rare case of a 38-year-old nulliparous woman who underwent a relatively minor and straightforward open myomectomy in a university hospital setting, during which the uterine cavity was not entered and there were no post-operative complications. Post-operatively the patient had oligomenorrhoea for over a year...
2014: Gynecologic and Obstetric Investigation
Chao Li, Min-ling Wei, Xiao-na Lin, Qiong-xiao Huang, Dong Huang, Song-ying Zhang
OBJECTIVE: To compare the efficacy of different time interval in the prevention of adhesion reformation after hysteroscopic adhesiolysis for moderate-severe Asherman's syndrome. METHODS: A total of 125 women with moderate-severe Asherman's syndrome undergoing hysteroscopic division of intrauterine adhesion were enrolled into this retrospective cohort study. All patients underwent second-look hysteroscopy after a certain period of the first hysteroscopic adhesiolysis, and the operation would be performed again if any adhesion existed...
December 3, 2013: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Jens J Kjer
Intrauterine adhesions (Asherman syndrome) are rare and mainly seen after delivery or abortion in the presence of retained placental tissue. This descriptive study aimed to identify common risk factors for intrauterine adhesions. In a 10-year period 61 women were identified with intrauterine adhesions. The pathology was suspected from symptoms, ultrasonography or on hysterosalpingography, but a final diagnosis could only be given after hysteroscopy. There was no definite evidence regarding methods for prevention and treatment of the disorder...
April 2014: Acta Obstetricia et Gynecologica Scandinavica
Alessandro Conforti, Carlo Alviggi, Antonio Mollo, Giuseppe De Placido, Adam Magos
Asherman syndrome is a debatable topic in gynaecological field and there is no clear consensus about management and treatment. It is characterized by variable scarring inside the uterine cavity and it is also cause of menstrual disturbances, infertility and placental abnormalities. The advent of hysteroscopy has revolutionized its diagnosis and management and is therefore considered the most valuable tool in diagnosis and management. The aim of this review is to explore the most recent evidence related to this condition with regards to aetiology, diagnosis management and follow up strategies...
2013: Reproductive Biology and Endocrinology: RB&E
Firoozeh Ahmadi, Maryam Javam
Several imaging methods have been applied for evaluation of suspected uterine synechiae; however, sonohysterography is yet recognised as a valid and accurate modality. Performing three-dimensional (3D) imaging along with sonohysterography enables evaluation of the uterus in the coronal plane to detect and grade the adhesions that characterise this condition. Thus, 3D sonohysterography is a minimally invasive and cost-effective tool for investigating suspected synechiae and is particularly useful when the transvaginal sonography findings are normal...
April 2014: Journal of Medical Imaging and Radiation Oncology
Salvatore Gizzo, Carlo Saccardi, Stefania Di Gangi, Anna Bertocco, Lucia Vendemiati, Lara Righetto, Tito Silvio Patrelli, Donato D'antona, Giovanni Battista Nardelli
The aim of this report was to define the best diagnostic and therapeutic approach when secondary amenorrhea is related to undiagnosed Asherman syndrome. We present a single case of secondary amenorrhea with a previous diagnosis of alterated hypothalamic-hypophysary regulation, with a component of ovarian function in probable reduction, which was evaluated in our department and resulted affected by Asherman's syndrome IV stage. We describe step by step the diagnosis and treatment of a previously misdiagnosed case of severe Asherman's syndrome...
March 2014: Minimally Invasive Therapy & Allied Technologies: MITAT
Xiaona Lin, Minling Wei, T C Li, Qiongxiao Huang, Dong Huang, Feng Zhou, Songying Zhang
OBJECTIVE: To compare the efficacy of intrauterine balloon, intrauterine contraceptive device and hyaluronic acid gel in the prevention of the adhesion reformation after hysteroscopic adhesiolysis for Asherman's syndrome. STUDY DESIGN: Retrospective cohort study of 107 women with Asherman's syndrome who were treated with hysteroscopic division of intrauterine adhesions. After hysteroscopic adhesiolysis, 20 patients had intrauterine balloon inserted, 28 patients had intrauterine contraceptive device (IUD) fitted, 18 patients had hyaluronic acid gel instilled into the uterine cavity, and 41 control subjects did not have any of the three additional treatment measures...
October 2013: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Thierry G Vancaillie, Rhonda Garad
No abstract text is available yet for this article.
March 13, 2013: Australian Nursing Journal: ANJ
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