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https://www.readbyqxmd.com/read/28079706/ibuprofen-before-exercise-does-not-prevent-cortical-bone-adaptations-to-training
#1
Vanessa D Sherk, R Dana Carpenter, Erin D Giles, Janine A Higgins, Robera M Oljira, Ginger C Johnson, Samuel Mills, Paul S MacLean
: Using a nonsteroidal anti-inflammatory drug (NSAID) before a single bout of mechanical loading can reduce bone formation response. It is unknown whether this translates to an attenuation of bone strength and structural adaptations to exercise training. PURPOSE: To determine whether NSAID use before exercise prevents increases in bone structure and strength in response to weight-bearing exercise. METHODS: Adult female Wistar rats (n=43) were randomized to Ibuprofen (IBU) or Vehicle (VEH) and Exercise (EX) or Sedentary (SED) groups in a 2x2 (drug, activity) ANCOVA design with body weight as the covariate, and data are reported as mean±SE...
January 10, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28079635/influences-of-age-obesity-and-adverse-drug-effects-on-balance-and-mobility-testing-scores-in-ambulatory-older-adults
#2
Eric Anson, Elizabeth Thompson, Brian L Odle, John Jeka, Zachary F Walls, Peter C Panus
BACKGROUND AND PURPOSE: The adverse effects of drugs may influence results on tests of mobility and balance, but the drug-specific impact is not identified when using these tests. We propose that a quantitative drug index (QDI) will assist in assessing fall risk based on these tests, when combined with other fall risk variables. METHODS: Fifty-seven community-dwelling older adults who could walk independently on a treadmill and had Mini-Mental State Examination (MMSE) scores equal to or greater than 24 participated...
January 10, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28072632/asc-methylation-and-interleukin-1%C3%AE-are-associated-with-aerobic-capacity-in-heart-failure
#3
Brittany Butts, Javed Butler, Sandra B Dunbar, Elizabeth Corwin, Rebecca A Gary
BACKGROUND: Aerobic capacity, as measured by peak oxygen uptake (V[Combining Dot Above]O2), is one of the most powerful predictors of prognosis in heart failure (HF). Inflammation is a key factor contributing to alterations in aerobic capacity, and interleukin (IL)-1 cytokines are implicated in this process. The adaptor protein ASC is necessary for inflammasome activation of IL-1β and IL-18. ASC expression is controlled through epigenetic modification; lower ASC methylation is associated with worse outcomes in HF...
January 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28069392/characterization-and-validation-of-a-split-belt-treadmill-for-measuring-hindlimb-ground-reaction-forces-in-able-bodied-and-spinalized-felines
#4
Marko Dimiskovski, Richard Scheinfield, Dwight Higgin, Alexander Krupka, Michel A Lemay
BACKGROUND: The measurement of ground reaction forces (GRFs) in animals trained to locomote on a treadmill after spinal cord injury (SCI) could prove valuable for evaluating training outcomes; however, quantitative measures of the GRFs in spinal felines are limited. NEW METHOD: A split belt treadmill was designed and constructed to measure the GRFs of feline hindlimbs during stepping. The treadmill consists of two independent treadmill assemblies, each mounted on a force plate...
January 6, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28068799/is-in-stent-restenosis-after-a-successful-coronary-stent-implantation-due-to-stable-angina-associated-with-tg-hdl-c-ratio
#5
Harun Kundi, Ahmet Korkmaz, Ahmet Balun, Hulya Cicekcioglu, Emrullah Kiziltunc, Koray Gursel, Mustafa Cetin, Ender Ornek, Mehmet Ileri
We examined the impact of the preprocedural triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) ratio on risk of in-stent restenosis (ISR). Patients with typical anginal symptoms and/or positive treadmill or myocardial perfusion scintigraphy test results who underwent successful coronary stent implantation due to stable angina were examined; 1341 patients were enrolled. The hospital files of the patients were used to gather data. Cox regression analysis showed that the TG/HDL-C ratio was independently associated with the presence of ISR ( P < ...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28067735/migraine-with-aura-or-sports-related-concussion-case-report-pathophysiology-and-multidisciplinary-approach-to-management
#6
Michael J Ellis, Dean Cordingley, Richard Girardin, Lesley Ritchie, Janine Johnston
The evaluation and management of athletes presenting with clinical features of migraine headache with aura in the setting of sports-related head trauma is challenging. We present a case report of a 15-yr-old boy with a history of migraine with visual aura that developed acute visual disturbance and headache after a head injury during an ice hockey game. The patient underwent comprehensive assessment at a multidisciplinary concussion program, including neuro-ophthalmological examination, neurocognitive testing, and graded aerobic treadmill testing...
January 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28064384/gut-microbiota-composition-associated-with-alterations-in-cardiorespiratory-fitness-and-psychosocial-outcomes-among-breast-cancer-survivors
#7
Jesseca A Paulsen, Travis S Ptacek, Stephen J Carter, Nianjun Liu, Ranjit Kumar, LaKeshia Hyndman, Elliot J Lefkowitz, Casey D Morrow, Laura Q Rogers
PURPOSE: In this proof-of-concept pilot study, our purpose was to determine correlations between gut microbiota composition and alterations in cardiorespiratory fitness and psychosocial outcomes among post-primary treatment breast cancer survivors (BCS). METHODS: Composition of the gut microbiota in BCS (n = 12) was assessed at baseline (M0) and at the end of 3 months (M3) using Illumina MiSeq DNA Sequencing of the 16S rRNA gene. Gut microbiota composition was analyzed using the QIIME bioinformatics software and represented through diversity metrics and taxa analyses...
January 7, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28060977/-validation-of-the-borg-scale-in-participants-with-type-2-diabetes-mellitus
#8
Walter Rosales, Cristian Cofré, Cicchitti Alejandra, Celina Bertona, Alejandro Vizcaya, Joaquín González, Jorge Bajuk, Martín Rodríguez
BACKGROUND: Borg Rating of Perceived Exertion Scale (RPE) is a psychophysiological measurements that translates physical stimuli to a psychological construct, which is perceived exertion. Its use is simple and it represents the effort perception. Each number of the scale is associated with a heart rate or percentage of maximal oxygen consumption (VO2max), which estimates the intensity of exercise. AIM: To validate RPE scale in patients with type 2 diabetes mellitus (DM2)...
September 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28058238/sedentary-behavior-physical-activity-and-cardiorespiratory-fitness-on-leukocyte-telomere-length
#9
Meghan K Edwards, Paul D Loprinzi
Background: Emerging work is starting to investigate the cumulative effects of moderate-to-vigorous physical activity (MVPA), sedentary behavior and cardiorespiratory fitness on health. The objective of this study was to examine the cumulative and independent associations of MVPA, sedentary behavior and cardiorespiratory fitness on leukocyte telomere length (LTL). Methods: Data from the 1999-2002 National Health and Nutrition Examination Survey (NHANES) were used (N = 1868 adults 20+ years); analyzed in 2016...
2017: Health Promotion Perspectives
https://www.readbyqxmd.com/read/28050921/influence-of-dietary-acid-load-on-exercise-performance
#10
Catherine Applegate, Mackenzie Mueller, Krystle E Zuniga
Diet composition can affect systemic pH and acid-base regulation, which may in turn influence exercise performance. An acidic environment in the muscle impairs performance and contributes to fatigue; therefore, current trends in sports nutrition place importance on maximizing the alkalinity of the body with ergogenic aids and dietary strategies. This review examines the evidence on the effects of dietary manipulations on acid load and exercise performance. Ten studies that investigated the effect of high versus low dietary acid loads on athletic performance generally identified that low dietary acid loads increased plasma pH, but did not consistently improve exercise performance at maximal or submaximal exercise intensities...
January 4, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28049109/ci2-for-creating-and-comparing-confidence-intervals-for-time-series-bivariate-plots
#11
David R Mullineaux
Currently no method exists for calculating and comparing the confidence-intervals (CI) for the time-series of a bivariate plot. The study's aim was to develop 'CI2' as a method to calculate the CI on time-series bivariate plots, and to identify if the CI between two bivariate time-series overlap. The test data were the knee and ankle angles from 10 healthy participants running on a motorised standard-treadmill and non-motorised curved-treadmill. For a recommended 10+ trials, CI2 involved calculating 95% confidence-ellipses at each time-point, then taking as the CI the points on the ellipses that were perpendicular to the direction vector between the means of two adjacent time-points...
December 23, 2016: Gait & Posture
https://www.readbyqxmd.com/read/28045865/effects-of-aerobic-exercise-on-pain-sensitivity-heart-rate-recovery-and-health-related-quality-of-life-in-patients-with-chronic-musculoskeletal-pain
#12
Şeyda Öte Karaca, Nesrin Demirsoy, Zafer Günendi
We aimed to investigate the effects of aerobic exercise on pain perception, sensitivity, and health-related quality of life; to assess its effect on parasympathetic tonus by analysis of heart rate recovery; and to examine the effects of parasympathetic tone on pain sensitivity in patients with chronic musculoskeletal pain. Fifty patients with chronic musculoskeletal pain were randomized into two groups: control group (C group) and aerobic exercise group (AE group). Both groups received conventional physical therapy for 2 weeks; the AE group performed submaximal aerobic exercise on a treadmill for 30 min additionally...
December 29, 2016: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28045554/an-aerobic-exercise-program-for-young-people-with-cerebral-palsy-in-specialist-schools-a-phase-i-randomized-controlled-trial
#13
Stacey L Cleary, Nicholas F Taylor, Karen J Dodd, Nora Shields
PURPOSE: To evaluate the safety, adherence, and estimates of effect of an aerobic exercise program in specialist schools for young people with cerebral palsy. METHODS: Nineteen students with cerebral palsy were randomly allocated to an intervention group who completed an aerobic exercise program (27 sessions over nine weeks) or a control group who completed social/art activities over the same time. RESULTS: There were no serious adverse events and the exercise program was completed with high rates of attendance (77%) and adherence to target heart rate zones (79%)...
January 3, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28045340/the-sensitivity-of-the-alternative-maximal-accumulated-oxygen-deficit-method-to-discriminate-training-status
#14
Alessandro M Zagatto, Fabio Y Nakamura, Fabio Milioni, Willian E Miyagi, Rodrigo A B de Poli, Johnny Padulo, Nicola L Bragazzi, Marcelo Papoti
The purpose of the study was to investigate the sensitivity of an alternative maximal accumulated oxygen deficit (MAODALT) method to discriminate the "anaerobic" capacity while comparing: least trained (LT) participants (n = 12), moderately trained (MT) participants (n = 12), endurance trained (ET) participants (n = 16), and rugby (RG) players (n = 11). Participants underwent a graded exercise test on a treadmill and a supramaximal effort for assessing MAODALT. MAODALT was calculated as the sum of oxygen equivalents from the phosphagen and glycolytic metabolic pathways...
January 3, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28039074/caffeine-stimulates-voluntary-wheel-running-in-mice-without-increasing-aerobic-capacity
#15
Gerald C Claghorn, Zoe Thompson, Kristianna Wi, Lindsay Van, Theodore Garland
The "energy drink" Red Bull and the "sports drink" Gatorade are often marketed to athletes, with claims that they cause performance gains. However, both are high in sugars, and also consumed by non-athletes. Few studies have addressed the effects of these drinks or their biologically active components in rodent exercise models. We used three experiments to test effects on both voluntary exercise behavior and maximal aerobic capacity in lines of mice known to differ in "athletic" traits. Mice from four replicate High Runner (HR) lines have been selectively bred for voluntary running on wheels, and run approximately three times as many revolutions per day as do mice from four non-selected Control (C) lines...
December 28, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/28034719/effects-of-gait-training-with-body-weight-support-on-a-treadmill-vs-overground-for-individuals-with-stroke
#16
Gabriela L Gama, Melissa L Celestino, José A Barela, Larry Forrester, Jill Whitall, Ana M F Barela
OBJECTIVE: To investigate the effects of gait training with body weight support on a treadmill vs. overground in individuals with chronic stroke. DESIGN: Randomized controlled trial. SETTING: University research laboratory PARTICIPANTS: Twenty-eight individuals with chronic stroke (> 6 months). INTERVENTIONS: Participants were randomly assigned to receive gait training with BWS on a treadmill (n=14) or overground (n=14) three times a week for six weeks...
December 26, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28032628/heart-rate-recovery-in-hypertensive-patients-relationship-with-blood-pressure-control
#17
Y Yu, T Liu, J Wu, P Zhu, M Zhang, W Zheng, Y Gu
Delayed heart rate recovery (HRR) post treadmill exercise testing reflects autonomic dysfunction and is related to worse cardiovascular outcome. The present study compared HRR in normotensive subjects and hypertensive patients taking anti-hypertensive medications with controlled blood pressure (BP) and uncontrolled BP. A total of 279 consecutive patients with (n=140, HP) and without (n=139, N-HP) essential hypertension who were hospitalized in our department during May 2012 to March 2016 were included in this study...
December 29, 2016: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28031761/physiological-responses-during-the-time-limit-at-100-of-the-peak-velocity-in-the-carminatti-s-test-in-futsal-players
#18
Leandro Teixeira Floriano, Juliano Fernandes da Silva, Anderson Santiago Teixeira, Paulo Cesar do Nascimento Salvador, Naiandra Dittrich, Lorival José Carminatti, Lucas Loyola Nascimento, Luiz Guilherme Antonacci Guglielmo
The aim of this study was to investigate the physiological responses during the time limit at the intensity of the peak velocity of the Carminatti's test (T-CAR). Ten professional futsal players (age, 27.4 ± 5.8 years, body mass, 78.8 ± 8.5 kg, body height, 175.8 ± 6.8 cm, body fat mass, 14.1 ± 2.6%) took part in the study. The players performed three tests, with an interval of at least 48 hours, as follows: the T-CAR to determine the peak velocity and the maximal heart rate; an incremental treadmill protocol to determine the maximal physiological responses; and a time limit running test at the peak velocity reached in the T-CAR...
December 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28028469/comparison-between-mother-actigraph-wgt3x-bt-and-a-hand-tally-for-measuring-steps-at-various-walking-speeds-under-controlled-conditions
#19
Henrik Riel, Camilla Rams Rathleff, Pernille Møller Kalstrup, Niels Kragh Madsen, Elena Selmar Pedersen, Louise Bilenberg Pape-Haugaard, Morten Villumsen
INTRODUCTION: Walking is endorsed as health enhancing and is the most common type of physical activity among older adults. Accelerometers are superior to self-reports when measuring steps, however, if they are to be used by clinicians the validity is of great importance. The aim of this study was to investigate the criterion validity of Mother and ActiGraph wGT3X-BT in measuring steps by comparing the devices to a hand tally under controlled conditions in healthy participants. METHODS: Thirty healthy participants were fitted with a belt containing the sensor of Mother (Motion Cookie) and ActiGraph...
2016: PeerJ
https://www.readbyqxmd.com/read/28025364/-managing-the-placebo-effect-the-single-blind-placebo-lead-in-response-in-two-pain-models
#20
R Norman Harden, Meryem Saracoglu, Sara Connolly, Amy Kirsling, Kelly Comstock, Katherine Khazey, Trevor Gerson, John Burns
OBJECTIVE: "Placebo effects" in analgesic medication trials for chronic pain are pervasive; however, little is known regarding mechanisms or factors that may influence the presence or magnitude of these effects. Our objective is to consider elements of the placebo response in the context of two pain models using a "single-blind placebo lead-in" design (SBPLI). METHODS: As part of two pilot drug trials using knee osteoarthritis (KOA) and non-radicular low back pain (LBP) subjects, SBPLI protocols were conducted...
December 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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