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3rd third line metastatic breast cancer

R Colomer, P Hall, M Szkultecka-Debek, R C Bondi, A Flinois, S Auziere, J Y Le Cléac'h
PURPOSE: The landscape of HER2+ metastatic breast cancer (mBC) treatment is changing due to the availability of new anti-HER2 drugs. The purpose of this study was to assess the current treatment patterns and sequences used in HER2+ mBC in the real-world setting. Secondary objectives were to describe the factors that influence the decision to prescribe a first and second-line antitumour treatment. METHODS: Retrospective chart review of 3068 cases in Spain, Italy, the Netherlands and the UK...
February 2018: Breast Cancer Research and Treatment
Takashi Emoto, Kiyoshi Yoshikawa, Yasuhiko Yoshioka, Riichirou Nezu, Masahiro Fujikawa, Makoto Fujii, Shouhei Maeda, Yoshihisa Naka, Takamitu Komaki
We studied 13 women aged 29-62 years for response to weekly administration of paclitaxel for metastatic breast cancer. Paclitaxel was administered by 1-hour intravenous infusion at a dose of 60-80 mg/m2 once a week. Administration was continued for 3 weeks with a 1-week rest for at least 3 cycles. This was first-line treatment in 1 patient, second-line treatment in 7, and third-line treatment in 5. The overall response rate was 68% among 13 partial responders and there were no complete responders. By recurrence site, the response rate was 71% in the liver, 75% in the lung, 18% in bone, and 67% at local sites...
June 2003: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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