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https://www.readbyqxmd.com/read/28944752/a-randomised-controlled-study-of-the-effectiveness-of-breathing-retraining-exercises-taught-by-a-physiotherapist-either-by-instructional-dvd-or-in-face-to-face-sessions-in-the-management-of-asthma-in-adults
#1
Mike Thomas, Anne Bruton, Paul Little, Stephen Holgate, Amanda Lee, Lucy Yardley, Steve George, James Raftery, Jennifer Versnel, David Price, Ian Pavord, Ratko Djukanovic, Michael Moore, Sarah Kirby, Guiqing Yao, Shihua Zhu, Emily Arden-Close, Manimekalai Thiruvothiyur, Frances Webley, Mark Stafford-Watson, Elizabeth Dixon, Lynda Taylor
BACKGROUND: Asthma control is suboptimal, resulting in quality of life (QoL) impairment and costs. Breathing retraining exercises have evidence of effectiveness as adjuvant treatment, but are infrequently used. OBJECTIVES: To transfer the contents of a brief (three-session) physiotherapist-delivered breathing retraining programme to a digital versatile disc (DVD) and booklet format; to compare the effectiveness of the self-guided intervention with that of 'face-to-face' physiotherapy and usual care for QoL and other asthma-related outcomes; to perform a health economic assessment of both interventions; and to perform a process evaluation using quantitative and qualitative methods...
September 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28944553/outcomes-for-bipolar-patients-assessed-in-the-french-expert-center-network-a-2-year-follow-up-observational-study-fondamental-advanced-centers-of-expertise-for-bipolar-disorder-face-bd
#2
Chantal Henry, Ophelia Godin, Philippe Courtet, Jean-Michel Azorin, Sébastien Gard, Frank Bellivier, Mircea Polosan, Jean-Pierre Kahn, Paul Roux, Valerie Aubin, Dominique Costagliola, Marion Leboyer, Bruno Etain
OBJECTIVE: A new health care system for patients with bipolar disorders was established in France under the auspices of Fondation FondaMental, based on thorough clinical assessment of patients and on close collaborations between expert centers and referring practitioners. We report the results of outcomes after 2 years of observational follow-up of adult patients assessed within the network. METHOD: A total of 984 patients were included in the study. We compared several parameters (e...
September 12, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28943420/impact-of-hospital-caseload-and-elective-admission-on-outcomes-following-extracranial-intracranial-bypass-surgery
#3
Hesam Akbarian-Tefaghi, Piyush Kalakoti, Hai Sun, Kanika Sharma, Jai Deep Thakur, Devi Prasad Patra, Rimal H Dossani, Amey Savardekar, Christina Notarianni, Gregory J Zipfel, Anil Nanda
BACKGROUND: Limited information exists evaluating the impact of hospital caseload and elective admission on outcomes following patients undergoing extracranial-intracranial (ECIC) bypass surgery. Using the Nationwide Inpatient Sample (NIS) for the years 2001 through 2014, we evaluated the impact of hospital caseload and elective admission on outcomes following bypass. METHODS: In an observational cohort study, weighted estimates were used to investigate the association of hospital caseload and elective admission on short-term outcomes following bypass surgery using multivariable regression techniques...
September 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28941748/impact-of-triggering-events-on-outcomes-of-acute-heart-failure
#4
Yasuyuki Shiraishi, Shun Kohsaka, Takayuki Abe, Kazumasa Harada, Tetsuro Miyazaki, Takamichi Miyamoto, Kiyoshi Iida, Shuzou Tanimoto, Mayuko Yagawa, Makoto Takei, Yuji Nagatomo, Toru Hosoda, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
BACKGROUND: The onset of acute heart failure is known to be associated with increased physical activity and other specific behaviors that can trigger hemodynamic deterioration. This analysis aimed to describe the distribution of triggers in patients hospitalized for acute heart failure, and investigate their effects on in-hospital outcomes. METHODS: Consecutive patients hospitalized for acute heart failure between 2010-2014 were registered in a multicenter data registration system (72 institutions within Tokyo, Japan)...
September 20, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28941618/waning-protection-of-influenza-vaccination-during-four-influenza-seasons-2011-2012-to-2014-2015
#5
J Puig-Barberà, A Mira-Iglesias, M Tortajada-Girbés, F X López-Labrador, J Librero-López, J Díez-Domingo, M Carballido-Fernández, C Carratalá-Munuera, P Correcher-Medina, V Gil-Guillén, R Limón-Ramírez, J Mollar-Maseres, M C Otero-Reigada, H Schwarz
BACKGROUND: Concerns have been raised about intraseasonal waning of the protection conferred by influenza vaccination. METHODS: During four influenza seasons, we consecutively recruited individuals aged 18years or older who had received seasonal influenza vaccine and were subsequently admitted to the hospital for influenza infection, asassessed by reverse transcription polymerase chain reaction. We estimated the adjusted odds ratio (aOR) of influenza infection by date of vaccination, defined by tertiles, as early, intermediate or late vaccination...
September 20, 2017: Vaccine
https://www.readbyqxmd.com/read/28940236/using-weighted-hospital-service-area-networks-to-explore-variation-in-preventable-hospitalization
#6
Michael O Falster, Louisa R Jorm, Alastair H Leyland
OBJECTIVE: To demonstrate the use of multiple-membership multilevel models, which analytically structure patients in a weighted network of hospitals, for exploring between-hospital variation in preventable hospitalizations. DATA SOURCES: Cohort of 267,014 people aged over 45 in NSW, Australia. STUDY DESIGN: Patterns of patient flow were used to create weighted hospital service area networks (weighted-HSANs) to 79 large public hospitals of admission...
September 22, 2017: Health Services Research
https://www.readbyqxmd.com/read/28940216/zeroing-in-on-red-blood-cell-unit-expiry
#7
Fathima Ayyalil, Greg Irwin, Bryony Ross, Michael Manolis, Anoop K Enjeti
BACKGROUND: Expiry of red blood cell (RBC) units is a significant contributor to wastage of precious voluntary donations. Effective strategies aimed at optimal resource utilization are required to minimize wastage. STUDY DESIGN AND METHODS: This retrospective study analyzed the strategic measures implemented to reduce expiry of RBC units in an Australian tertiary regional hospital. The measures, which included inventory rearrangement, effective stock rotation, and the number of emergency courier services required during a 24-month period, were evaluated...
September 20, 2017: Transfusion
https://www.readbyqxmd.com/read/28939928/acute-heart-failure-an-unmet-medical-need
#8
REVIEW
A G Rigopoulos, C Bakogiannis, R de Vecchis, S Sakellaropoulos, M Ali, M Teren, M Matiakis, C Tschoepe, M Noutsias
Despite recent advances in the management of heart failure with reduced ejection fraction (HFrEF), the burden of acute heart failure (AHF) remains significant with a high morbidity and mortality that has not been improved by any treatment modality. A meta-analysis summarized the study results on the effects of tolvaptan on AHF, which failed to demonstrate an improvement in short-term and long-term mortality, length of hospital stay and reduced frequency of worsening heart failure (WHF). Similar trial results were also reported in other AHF studies, such as the ASCEND-HF and the RELAX-AHF-2 trials...
September 22, 2017: Herz
https://www.readbyqxmd.com/read/28939715/precatheterization-use-of-p2y12-inhibitors-in-non-st-elevation-myocardial-infarction-patients-undergoing-early-cardiac-catheterization-and-in-hospital-coronary-artery-bypass-grafting-insights-from-the-national-cardiovascular-data-registry-%C3%A2
#9
Marwan Badri, Amr Abdelbaky, Shuang Li, Karen Chiswell, Tracy Y Wang
BACKGROUND: Current guidelines recommend early P2Y12 inhibitor administration in non-ST-elevation myocardial infarction, but it is unclear if precatheterization use is associated with longer delays to coronary artery bypass grafting (CABG) or higher risk of post-CABG bleeding and transfusion. This study examines the patterns and outcomes of precatheterization P2Y12 inhibitor use in non-ST-elevation myocardial infarction patients who undergo CABG. METHODS AND RESULTS: Retrospective analysis was done of 20 304 non-ST-elevation myocardial infarction patients in the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry (2009-2014) who underwent catheterization within 24 hours of admission and CABG during the index hospitalization...
September 22, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28939545/protocol-for-co-design-development-and-open-trial-of-a-prototype-game-based-ehealth-intervention-to-treat-anxiety-in-young-people-with-long-term-physical-conditions
#10
Hiran Thabrew, Karolina Stasiak, Sally Merry
BACKGROUND: Approximately 10% to 12% of New Zealand young people (and 21% of Maori young people) have long-term physical conditions and are more likely to develop psychological problems, particularly anxiety and depression. Delayed treatment leads to worse management of physical conditions, school absence, and poorer long-term outcomes. Recently, electronic health (eHealth) interventions have been shown to be as good as face-to-face therapy and biofeedback techniques have been shown to enhance relaxation during the treatment of anxiety...
September 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28937272/effects-of-movement-music-therapy-with-a-percussion-instrument-on-physical-and-frontal-lobe-function-in-older-adults-with-mild-cognitive-impairment-a-randomized-controlled-trial
#11
Nobuko Shimizu, Tomohiro Umemura, Masahiro Matsunaga, Takayoshi Hirai
OBJECTIVES: We tested the hypothesis that performing a rhythmic physical task accompanied by a cognitive task, such as multitask movement music therapy (MMT) involving repetitive rhythmic movement with a musical instrument (the Naruko clapper), may improve pre-frontal cortex (PFC) function and cognitive performance. METHOD: Forty-five older adult participants with MCI (74.62 ± 5.05 years) participated in this randomized, controlled, single-blind intervention trial...
September 22, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28936931/patient-perspectives-on-transitions-of-surgical-care-examining-the-complexities-and-interdependencies-of-care
#12
Maynor G González, Kristin N Kelly, Ann M Dozier, Fergal Fleming, John R T Monson, Adan Z Becerra, Christopher T Aquina, Christian P Probst, Bradley J Hensley, Nick Sevdalis, Katia Noyes
This study examined a thematic network aimed at identifying experiences that influence patients' outcomes (e.g., patients' satisfaction, anxiety, and discharge readiness) in an effort to improve care transitions and reduce patient burden. We drew upon the Sociology and Complexity Science Toolkit to analyze themes derived from 61 semistructured, longitudinal interviews with 20 patients undergoing either a benign or malignant colorectal resection (three interviews per patient over a 30-day after hospital discharge)...
October 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28936558/how-do-treatment-aims-in-the-last-phase-of-life-relate-to-hospitalizations-and-hospital-mortality-a-mortality-follow-back-study-of-dutch-patients-with-five-types-of-cancer
#13
Mariska Oosterveld-Vlug, Gé Donker, Femke Atsma, Linda Brom, Yvonne de Man, Stef Groenewoud, Bregje Onwuteaka-Philipsen
PURPOSE: The purpose of this study is to describe and compare the relation between treatment aims, hospitalizations, and hospital mortality for Dutch patients who died from lung, colorectal, breast, prostate, or pancreatic cancer. METHODS: A mortality follow-back study was conducted within a sentinel network of Dutch general practitioners (GPs), who recorded the end-of-life care of 691 patients who died from one of the abovementioned cancer types between 2009 and 2015...
September 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28935126/-pharmaceutical-record-s-use-in-drugs-sales-service-analysis-of-five-months-of-experimentation
#14
M France, A-S Leromain, C Jarre, M Hellot-Guersing, C Derharoutunian, A Gadot, R Roubille
OBJECTIVE: The pharmaceutical record integrated in the health insurance card is now exploitable by hospital pharmacists. The aim of this study is to assess the impact of pharmaceutical record's use in hospital drugs sales service and the relevance of this tool to secure the ambulatory dispensing of drugs. METHOD: All patients admitted in hospital drugs sales service between June and October 2016 were included. With the patient's consent, pharmaceutical record was created and/or consulted and implemented...
September 18, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28934915/-significant-intraventricular-hemorrhage-is-more-likely-in-very-preterm-infants-born-by-vaginal-delivery-a-multi-centre-retrospective-cohort-study
#15
Islam Gamaleldin, David Harding, Dimitrios Siassakos, Tim Draycott, David Odd
OBJECTIVES: To determine the association between mode of delivery (vaginal delivery [VD] versus cesarean section [CS]) and the rate of significant intraventricular hemorrhage (sIVH) in preterm infants. METHODS: A multicenter retrospective cohort study, based on data collected from the Vermont Oxford Network database. Infants born between 23 and 31(+6) weeks of gestational age between 2001 and 2014 were identified. Exposure was the mode of birth (VD versus CS). Primary outcome was development of sIVH...
September 21, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28934089/postpartum-hemorrhage-with-transfusion-trends-near-misses-risk-factors-and-management-at-the-scale-of-a-perinatal-network
#16
M Marocchini, J Lauféron, C Quantin, P Sagot
OBJECTIVES: To analyze temporal trends and management of postpartum hemorrhage (PPH) with transfusion and its related maternal near-miss (MNM) cases between 2006 and 2014 and to study risk factors. MATERIAL AND METHODS: This retrospective cohort study from two prospective databases included 156,047 women giving birth in all the maternity hospitals of Burgundy. We analyzed temporal trends and the distribution of PPH with transfusion, the circumstances of transfer of patients between hospitals and factors associated with PPH with transfusion...
May 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28933171/-the-current-problems-related-to-nosocomial-infections-and-antibiotic-resistance-today
#17
Renata Tejkalová
Nosocomial, also known as hospital acquired infections, are today considered to be an important indicator of the quality of health care in all health establishments. They involve an undesirable complication of the provided health care with a number of negative consequences, such as increased morbidity and mortality, longer time of hospitalization and higher costs. Their incidence at present is also related, among other things, to the broadening, sometimes invasive technical possibilities of diagnosing and therapy...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28931761/periodontal-induced-chronic-inflammation-triggers-macrophage-secretion-of-ccl12-to-inhibit-fibroblast-mediated-cardiac-wound-healing
#18
Kristine Y DeLeon-Pennell, Rugmani Padmanabhan Iyer, Osasere K Ero, Courtney A Cates, Elizabeth R Flynn, Presley L Cannon, Mira Jung, De'Aries Shannon, Michael R Garrett, William Buchanan, Michael E Hall, Yonggang Ma, Merry L Lindsey
Chronic inflammatory diseases, such as periodontal disease, associate with adverse wound healing in response to myocardial infarction (MI). The goal of this study was to elucidate the molecular basis for impaired cardiac wound healing in the setting of periodontal-induced chronic inflammation. Causal network analysis of 168 inflammatory and extracellular matrix genes revealed that chronic inflammation induced by a subseptic dose of Porphyromonas gingivalis lipopolysaccharide (LPS) exacerbated infarct expression of the proinflammatory cytokine Ccl12...
September 21, 2017: JCI Insight
https://www.readbyqxmd.com/read/28931244/the-importance-of-frailty-in-the-assessment-of-influenza-vaccine-effectiveness-against-influenza-related-hospitalization-in-elderly-people
#19
Melissa K Andrew, Vivek Shinde, Lingyun Ye, Todd Hatchette, François Haguinet, Gael Dos Santos, Janet E McElhaney, Ardith Ambrose, Guy Boivin, William Bowie, Ayman Chit, May ElSherif, Karen Green, Scott Halperin, Barbara Ibarguchi, Jennie Johnstone, Kevin Katz, Joanne Langley, Jason Leblanc, Mark Loeb, Donna MacKinnon-Cameron, Anne McCarthy, Allison McGeer, Jeff Powis, David Richardson, Makeda Semret, Grant Stiver, Sylvie Trottier, Louis Valiquette, Duncan Webster, Shelly A McNeil
Background: Influenza is an important cause of morbidity and mortality among older adults. Even so, effectiveness of influenza vaccine for older adults has been reported to be lower than for younger adults, and the impact of frailty on vaccine effectiveness (VE) and outcomes is uncertain. We aimed to study VE against influenza hospitalization in older adults, focusing on the impact of frailty. Methods: We report VE of trivalent influenza vaccine (TIV) in people ≥65 years of age hospitalized during the 2011-2012 influenza season using a multicenter, prospective, test-negative case-control design...
August 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28929882/supporting-hospital-renewal-through-strategic-environmental-sustainability-programs
#20
Peter Pisters, Belinda Bien, Stewart Dankner, Ed Rubinstein, Fatima Sheriff
Although the impact the environment can have on human health is well understood, the healthcare system's impact on the environment is a topic that's only been explored since the mid-1990s. More recent has been a realization of the risks that climate change poses to health and healthcare. Although there are numerous direct benefits for hospitals adapting environmental sustainability programs, this article examines how the systemic approach taken by the University Health Network's (UHN) Energy & Environment program not only improves the hospital's environmental performance and provides significant cost savings but also supports several areas of focus that are part of UHN's current journey of renewal...
March 2017: Healthcare Management Forum
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