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https://www.readbyqxmd.com/read/28208685/hollow-fiber-supported-liquid-membrane-extraction-combined-with-hplc-uv-for-simultaneous-preconcentration-and-determination-of-urinary-hippuric-acid-and-mandelic-acid
#1
Abdulrahman Bahrami, Farhad Ghamari, Yadollah Yamini, Farshid Ghorbani Shahna, Abbas Moghimbeigi
This work describes a new extraction method with hollow-fiber liquid-phase microextraction based on facilitated pH gradient transport for analyzing hippuric acid and mandelic acid in aqueous samples. The factors affecting the metabolites extraction were optimized as follows: the volume of sample solution was 10 mL with pH 2 containing 0.5 mol·L(-1) sodium chloride, liquid membrane containing 1-octanol with 20% (w/v) tributyl phosphate as the carrier, the time of extraction was 150 min, and stirring rate was 500 rpm...
February 12, 2017: Membranes
https://www.readbyqxmd.com/read/28202057/improvement-of-memory-and-learning-by-intracerebroventricular-microinjection-of-t3-in-rat-model-of-ischemic-brain-stroke-mediated-by-upregulation-of-bdnf-and-gdnf-in-ca1-hippocampal-region
#2
Tahmineh Mokhtari, Mohammad Akbari, Fatemeh Malek, Iraj Ragerdi Kashani, Tayebeh Rastegar, Farshid Noorbakhsh, Mahmoud Ghazi-Khansari, Fatemeh Attari, Gholamreza Hassanzadeh
BACKGROUND: Ischemic stroke is a common leading cause of death and disability with lack of effective therapies. In this study, T3 was intra-ventricularly injected to evaluate gene expression and protein concentration of and brain-derived neurotrophic factor (BDNF) and Glial cell-derived neurotrophic factor (GDNF) in hippocampal CA1 region in rat model of brain ischemia/reperfusion (I/R). METHODS: In this study, transient middle cerebral artery occlusion (tMCAo) was used as model of ischemic brain stroke...
February 15, 2017: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28197353/scaphoid-fracture-in-a-patient-with-a-scaphotrapezial-synostosis-a-case-report-and-literature-review
#3
Soliman Noureldin, Mohammed Ali, Farshid Fallahi, Thomas Dehler
Introduction. Scaphotrapezial synostosis has been rarely reported in the literature and only one case underwent surgical treatment for scaphoid fracture. Presentation of Case. A 15-year-old male presented with a painful left wrist following a fall. The initial radiographs showed a displaced scaphoid proximal pole fracture and a Scaphotrapezial synostosis. The fracture was then fixed percutaneously with satisfactory outcome. Discussion. Scaphotrapezial synostoses are very rare and most found in patients with multiple congenital anomalies or as part of a hereditary syndrome...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28191681/a-time-efficient-acquisition-protocol-for-multipurpose-diffusion-weighted-microstructural-imaging-at-7-tesla
#4
Farshid Sepehrband, Kieran O'Brien, Markus Barth
PURPOSE: Several diffusion-weighted MRI techniques have been developed and validated during the past 2 decades. While offering various neuroanatomical inferences, these techniques differ in their proposed optimal acquisition design, preventing clinicians and researchers benefiting from all potential inference methods, particularly when limited time is available. This study reports an optimal design that enables for a time-efficient diffusion-weighted MRI acquisition scheme at 7 Tesla...
February 12, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28178123/spectrum-of-pediatric-tumors-diagnosed-by-fine-needle-aspiration-cytology
#5
Sadegh Shirian, Yahya Daneshbod, Sezaneh Haghpanah, Bijan Khademi, Farshid Noorbakhsh, Amir Ghaemi, Ziba Mosayebi
Pediatric tumors differ markedly from adult tumors in their nature, distribution, and prognosis. In this 10-year retrospective study, we present our experience with fine-needle aspiration (FNA) in pediatric patients 18 years of age and younger and correlate relationship between gender with organ, diagnosis, malignancy, and age. In our study, FNA material of pediatric tumors or masses with 18 years aged and younger were analyzed retrospectively.All FNAs in pediatric patients during this time period were identified and analyzed for age, gender, cytologic diagnosis, and site of aspiration...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28167960/addition-of-ceftriaxone-and-amikacin-to-a-ciprofloxacin-plus-metronidazole-regimen-for-preventing-infectious-complications-of-transrectal-ultrasound-guided-prostate-biopsy-a-randomized-controlled-trial
#6
Mohammad-Hossein Izadpanahi, Kia Nouri-Mahdavi, Seyed Mahmood Majidi, Mohammad-Hatef Khorrami, Farshid Alizadeh, Mehrdad Mohammadi-Sichani
Background. The objective of this study was to evaluate the efficacy of adding single doses of ceftriaxone and amikacin to a ciprofloxacin plus metronidazole regimen on the reduction of infectious complications following transrectal ultrasound-guided prostate biopsy (TRUS Bx). Materials and Methods. Four hundred and fifty patients who were candidates for TRUS Bx were divided into two groups of 225 each. The control group received ciprofloxacin 500 mg orally every 12 hours together with metronidazole 500 mg orally every 8 hours from the day prior to the procedure until the fifth postoperative day...
2017: Advances in Urology
https://www.readbyqxmd.com/read/28166692/critical-sized-bone-defects-in-mandible-of-canine-model
#7
Sepanta Hosseinpour, Farshid Bastami
One of the major challengeable issues in bone tissue engineering is regeneration of critical-sized bone defects (CSBD). According to bone formation results of the article conducted by Liu et al "Mesenchymal stem cells systemically injected into femoral marrow of dogs home to mandibular defects to enhance new bone formation. Tissue Engineering Part A. 2014;20(3-4):883-92", we can conclude that creating the correct defect form and interrupting the natural bone healing cascade can be essential as well as creating the accurate defect size to have a true CSBD in animal model of the research...
February 6, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28144600/spatial-factors-affecting-the-frequency-of-pedestrian-traffic-crashes-a-systematic-review
#8
REVIEW
Ali Moradi, Hamid Soori, Amir Kavousi, Farshid Eshghabadi, Ensiyeh Jamshidi
CONTEXT: Considering the importance of pedestrian traffic crashes and the role of environmental factors in the frequency of crashes, this paper aimed to review the published evidence and synthesize the results of related studies for the associations between environmental factors and distribution of pedestrian-vehicular traffic crashes. EVIDENCE ACQUISITION: We searched all epidemiological studies from 1966 to 2015 in electronic databases. We found 2,828 studies...
December 2016: Archives of Trauma Research
https://www.readbyqxmd.com/read/28144116/a-method-to-obtain-correct-standard-uptake-values-in-pinnacle-treatment-planning-system-for-target-volume-delineation
#9
Farshid Salehzahi, Jason Tse, Jonathan Lee, Jothybasu Selvaraj
Standardized uptake value (SUV) is an advanced tool for quantitative tumor identification and metabolic target volume delineation (TVD) in diagnostic and therapeutic settings. It is thus important to establish a quality assured process to maintain the traceability of data correctly by positron emission tomography (PET) systems. Patient administration of (18)fluoro-deoxy-glucose is increasingly delivered by automated infusion systems (AISs). Whenever AIS is used, its accuracy and traceability measurement need verification...
October 2016: Journal of Medical Physics
https://www.readbyqxmd.com/read/28115223/assessment-of-the-efficacy-and-safety-of-fluticasone-propionate-and-salmeterol-delivered-as-a-combination-dry-powder-via-a-capsule-based-inhaler-versus-a-multi-dose-inhaler-in-patients-with-chronic-obstructive-pulmonary-disease
#10
Robert Chan, Ana R Sousa, Peter Hynds, Farshid Homayoun-Valiani, Dawn Edwards, Maggie Tabberer
BACKGROUND: This study tested the clinical non-inferiority of the fluticasone propionate/salmeterol combination 50/250 μg (FSC) Rotacaps(®)/Rotahaler(®) system, a single unit dose inhaler, with the multi-dose FSC Diskus(®) inhaler in adults with chronic obstructive pulmonary disease (COPD). METHODS: This multi-centre, randomised, double-blind, double-dummy, two-way cross-over study compared 12 weeks' treatment of FSC administered twice daily using Rotacaps/Rotahaler or Diskus...
January 20, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28112976/effects-of-cannabinoid-and-vanilloid-receptor-agonists-and-their-interaction-on-learning-and-memory-in-rats
#11
Mariam Shiri, Alireza Komaki, Shahrbanoo Oryan, Masoumeh Taheri, Hamidreza Komaki, Farshid Etaee
Despite previous findings on the effects of cannabinoid and vanilloid systems on learning and memory, the effects of the combined stimulation of these 2 systems on learning and memory have not been studied. Therefore, in this study, we tested the interactive effects of cannabinoid and vanilloid systems on learning and memory in rats by using passive avoidance learning (PAL) tests. Forty male Wistar rats were divided into the following 4 groups: (1) control (DMSO+saline), (2) WIN55,212-2, (3) capsaicin, and (4) WIN55,212-2 + capsaicin...
November 2, 2016: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28106453/giant-amplification-of-noise-in-fluctuation-induced-pattern-formation
#12
Tommaso Biancalani, Farshid Jafarpour, Nigel Goldenfeld
The amplitude of fluctuation-induced patterns might be expected to be proportional to the strength of the driving noise, suggesting that such patterns would be difficult to observe in nature. Here, we show that a large class of spatially extended dynamical systems driven by intrinsic noise can exhibit giant amplification, yielding patterns whose amplitude is comparable to that of deterministic Turing instabilities. The giant amplification results from the interplay between noise and nonorthogonal eigenvectors of the linear stability matrix, yielding transients that grow with time, and which, when driven by the ever-present intrinsic noise, lead to persistent large amplitude patterns...
January 6, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28095751/crispr-based-epigenome-editing-of-cytokine-receptors-for-the-promotion-of-cell-survival-and-tissue-deposition-in-inflammatory-environments
#13
Niloofar Farhang, Jonathan M Brunger, Joshua D Stover, Pratiksha I Thakore, Brandon Lawrence, Farshid Guilak, Charles A Gersbach, Lori A Setton, Robert D Bowles
Musculoskeletal diseases have been associated with inflammatory cytokine action, particularly action by TNF-α and IL-1β. These inflammatory cytokines promote apoptosis and senescence of cells in diseased tissue and extracellular matrix breakdown. Stem cell-based therapies are being considered for the treatment of musculoskeletal diseases, but the presence of these inflammatory cytokines will have similar deleterious action on therapeutic cells delivered to these environments. Methods that prevent inflammatory-induced apoptosis and pro-inflammatory signaling, in cell and pathway specific manners are needed...
January 17, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28087282/short-term-perioperative-teriparatide-therapy-for-the-prevention-of-medication-related-osteonecrosis-of-the-jaw-a-randomized-controlled-preclinical-study-in-rats
#14
Mohammad Zandi, Arash Dehghan, Amirhossein Mohammadi-Mofrad, Payam Amini, Farshid Vahdatinia
OBJECTIVE: Dentoalveolar procedures in patients receiving bisphosphonates and other antiresorptive agents are associated with an increased risk of medication-related osteonecrosis of the jaw (MRONJ). The aim of present study was to evaluate the effects of perioperative teriparatide (TPD) therapy in prevention of MRONJ. SUBJECTS AND METHODS: Two protocols of TPD therapy were studied. For protocol A, 25 TPD-treated (AT) and 25 control (AC) rats received 5 weekly injection of 0...
December 19, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28078246/the-effects-of-crocin-insulin-and-their-co-administration-on-the-heart-function-and-pathology-in-streptozotocin-induced-diabetic-rats
#15
Amir Abbas Farshid, Esmaeal Tamaddonfard, Masoumeh Moradi-Arzeloo, Navideh Mirzakhani
OBJECTIVE: Crocin is a saffron constituent with a potent anti-oxidant activity. The present study investigated the effects of crocin and insulin treatments (alone or in combination) on cardiac function and pathology in diabetic rats. MATERIALS AND METHODS: Diabetes was induced by intraperitoneal (i.p.) injection of streptozotocin (STZ, 50 mg/kg). Thereafter, crocin (5, 10 and 20 mg/kg, i.p.), subcutaneous (s.c.) injection of insulin (4 IU/kg) and their combination were administered for eight weeks...
November 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28077893/the-prediction-of-the-risk-level-of-pulmonary-embolism-and-deep-vein-thrombosis-through-artificial-neural-network
#16
Laleh Agharezaei, Zhila Agharezaei, Ali Nemati, Kambiz Bahaadinbeigy, Farshid Keynia, Mohammad Reza Baneshi, Abedin Iranpour, Moslem Agharezaei
BACKGROUND: Venous thromboembolism is a common cause of mortality among hospitalized patients and yet it is preventable through detecting the precipitating factors and a prompt diagnosis by specialists. The present study has been carried out in order to assist specialists in the diagnosis and prediction of the risk level of pulmonary embolism in patients, by means of artificial neural network. METHOD: A number of 31 risk factors have been used in this study in order to evaluate the conditions of 294 patients hospitalized in 3 educational hospitals affiliated with Kerman University of Medical Sciences...
October 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28070535/association-of-fas-a-670g-polymorphism-and-risk-of-uterine-leiomyoma-in-a-southeast-iranian-population
#17
Mohammadpour-Gharehbagh Abbas, Salimi Saeedeh, Keshavarzi Farshid, Zakerian Sepideh, Sajadian Mojtaba, Mokhtari Mojgan
BACKGROUND: Uterine leiomyoma (UL) is a benign tumor of uterine smooth muscle that affects women in reproductive ages. FAS has an important role in initial stages of apoptosis. Previous studies have shown an association between the FAS gene and tumorigenesis. In the present study, we evaluated the relationship between FAS A-670G (rs 1800682) and UL risk. METHODS: The FAS gene polymorphism of 155 women with UL and 157 healthy controls was analyzed by the polymerase chain reaction restriction fragment length polymorphism method...
October 2016: Reports of Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28066834/the-role-of-ventilation-mode-using-a-laryngeal-mask-airway-during-gynecological-laparoscopy-on-lung-mechanics-hemodynamic-response-and-blood-gas-analysis
#18
Mohammad Hossein Jarahzadeh, Iman Halvaei, Farshid Rahimi-Bashar, Shekoufeh Behdad, Rouhollah Abbasizadeh Nasrabady, Elahe Yasaei
BACKGROUND: There are two methods for ventilation in gynecological laparoscopy: volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV). OBJECTIVE: To compare the lung mechanics, hemodynamic response and arterial blood gas analysis and gas exchange of two modes of VCV and PCV using laryngeal mask airway (LMA) at different time intervals. MATERIALS AND METHODS: Sixty infertile women referred for diagnostic laparoscopy, based on ventilation mode, were randomly divided into two groups of VCV (tidal volume: 10 ml/kg) and PCV...
December 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28062979/contemporary-indications-for-diagnostic-open-biopsy-in-women-assessed-for-screen-detected-breast-lesions-a-ten-year-single-institution-series-of-814-consecutive-cases
#19
Gelareh Farshid, P Grantley Gill
PURPOSE: In contemporary practice, 5% of women with non-malignant needle biopsies of screen-detected lesions still require diagnostic open biopsy (OBx). Our aims are to (i) capture a snapshot of the contemporary indications for OBx in screen-detected lesions; (ii) determine upgrade rates to malignancy (DCIS or invasive cancer); (iii) identify indications with sufficiently low upgrades to justify avoidance of OBx and (iv) propose plausible non-surgical alternatives. METHODS: Between Jan 2005 and Dec 2014, women assessed for a screen-detected lesion and recommended for OBx are included...
January 6, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28057349/flow-patterns-in-the-jugular-veins-of-pulsatile-tinnitus-patients
#20
Evan Kao, Sarah Kefayati, Matthew R Amans, Farshid Faraji, Megan Ballweber, Van Halbach, David Saloner
Pulsatile Tinnitus (PT) is a pulse-synchronous sound heard in the absence of an external source. PT is often related to abnormal flow in vascular structures near the cochlea. One vascular territory implicated in PT is the internal jugular vein (IJV). Using computational fluid dynamics (CFD) based on patient-specific Magnetic Resonance Imaging (MRI), we investigated the flow within the IJV of seven subjects, four symptomatic and three asymptomatic of PT. We found that there were two extreme anatomic types classified by the shape and position of the jugular bulbs: elevated and rounded...
December 14, 2016: Journal of Biomechanics
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