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https://www.readbyqxmd.com/read/29323911/capillary-condensation-in-8-nm-deep-channels
#1
Junjie Zhong, Jason Riordon, Seyed Hadi Zandavi, Yi Xu, Aaron Harrinarine Persad, Farshid Mostowfi, David Sinton
Condensation at the nanoscale is essential to understanding many natural and synthetic systems relevant to water, air and energy. Despite its importance, the underlying physics of condensation initiation and propagation remain largely unknown at sub-10 nm, mainly due to the challenges of controlling and probing such small systems. Here we study the condensation of n-propane down to 8-nm confinement in a nanofluidic system, distinct from previous studies at ~100 nm. The condensation initiates significantly earlier in the 8-nm channels and it initiates from the entrance, in contrast to channels just 10-times larger...
January 11, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29321029/association-of-caries-experience-and-dental-plaque-with-sociodemographic-characteristics-in-elementary-school-aged-children-a-cross-sectional-study
#2
Saeed Bashirian, Samaneh Shirahmadi, Shabnam Seyedzadeh-Sabounchi, Ali Reza Soltanian, Akram Karimi-Shahanjarini, Farshid Vahdatinia
BACKGROUND: Dental caries among Iranian elementary school children aged 6-12 years continue to rise. To estimate treatment needs and guide health initiatives, current epidemiologic data are required. Such data are currently unavailable for dental health. The purpose of this study was to assess caries experience, dental plaque, and associated factors in elementary school-aged children from Iran. METHODS: In this cross-sectional study, 988 elementary school children aged 7-12 years were selected by multistage cluster sampling...
January 10, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29299787/spiritual-health-and-outcomes-in-muslim-icu-patients-a-nationwide-cross-sectional-study
#3
Farshid R Bashar, Amir Vahedian-Azimi, Mahmood Salesi, Mohammadreza Hajiesmaeili, Seyedpouzhia Shojaei, Behrooz Farzanegan, Reza Goharani, Seyed J Madani, Kivan G Moghaddam, Sevak Hatamian, Hosseinali J Moghaddam, Abilio Arrascaeta-Llanes, Andrew C Miller
The aim of the present study is to describe how religiosity and spirituality affect the psychiatric morbidity of Muslim intensive care unit (ICU) patients. We conducted a prospective nationwide cross-sectional study of ICU patients discharged from 45 medical centers spanning 31 proivinces in Iran. Adults (age ≥ 18 years) admitted to the ICU and treated with invasive mechanical ventilation were eligible. Nine validated survey tools were administered to detect direct and indirect associations between spiritual health (SH) and depression, anxiety, and post-traumatic disorder...
January 3, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29282315/dynamics-and-mechanisms-of-intracellular-calcium-waves-elicited-by-tandem-bubble-induced-jetting-flow
#4
Fenfang Li, Chen Yang, Fang Yuan, Defei Liao, Thomas Li, Farshid Guilak, Pei Zhong
One of the earliest events in cellular mechanotransduction is often an increase in intracellular calcium concentration associated with intracellular calcium waves (ICWs) in various physiologic or pathophysiologic processes. Although cavitation-induced calcium responses are believed to be important for modulating downstream bioeffects such as cell injury and mechanotransduction in ultrasound therapy, the fundamental mechanisms of these responses have not been elucidated. In this study, we investigated mechanistically the ICWs elicited in single HeLa cells by the tandem bubble-induced jetting flow in a microfluidic system...
December 27, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29277137/effects-of-stress-on-critical-care-nurses-a-national-cross-sectional-study
#5
Amir Vahedian-Azimi, Mohammadreza Hajiesmaeili, Mari Kangasniemi, Joana Fornés-Vives, Rita L Hunsucker, Farshid Rahimibashar, Mohammad A Pourhoseingholi, Leily Farrokhvar, Andrew C Miller
BACKGROUND: Health care is a demanding field, with a high level of responsibility and exposure to emotional and physical danger. High levels of stress may result in depression, anxiety, burnout syndrome, and in extreme cases, post-traumatic stress disorder. The aim of this study was to determine which personal, professional, and organizational variables are associated with greater perceived stress among critical care nurses for purposes of developing integrative solutions to decrease stress in the future...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29247253/perspectives-on-sharing-models-and-related-resources-in-computational-biomechanics-research
#6
Ahmet Erdemir, Peter J Hunter, Gerhard A Holzapfel, Leslie M Loew, John Middleton, Christopher R Jacobs, Perumal Nithiarasu, Rainald Lohner, Guowei Wei, Beth A Winkelstein, Victor H Barocas, Farshid Guilak, Joy Ku, Jennifer L Hicks, Scott Delp, Michael Sacks, Jeffrey A Weiss, Dr Gerard A Ateshian, Steve A Maas, Andrew D McCulloch, Grace C Y Peng
The role of computational modeling for biomechanics will be increasingly prominent. In computational biomechanics, model sharing can facilitate assessment of reproducibility, and can provide an opportunity for repurposing and reuse, and a venue for medical training. The community's desire to investigate biological and biomechanical phenomena crossing multiple systems, scales, and physical domains, also motivates sharing of modeling resources as blending of models developed by domain experts is anticipated. The goal of this article is to understand current perspectives in the biomechanics community for the sharing of computational models and related resources...
December 16, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29238925/combination-of-uvc-leds-and-ultrasound-for-peroxymonosulfate-activation-to-degrade-synthetic-dye-influence-of-promotional-and-inhibitory-agents-and-application-for-real-wastewater
#7
Mehdi Ahmadi, Farshid Ghanbari
Several efforts have been carried out to present an efficient method for PMS activation. This work presented the use of UVC-LEDs (light emitting diodes) and US (ultrasound) to activate PMS for decolorization of Direct Orange 26 (DO26). The performance of UVC-LEDs/US/PMS process was effective in a broad range of pH (3.0-9.0). Complete decolorization was obtained in only 12 min in pH = 7.0 and 1.5 mM PMS. Bicarbonate and nitrite ions showed inhibitory effect on decolorization while sulfate, chloride, and nitrate had no significant effect on the performance of the process...
December 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29236313/micrornas-and-exosomes-in-depression-potential-diagnostic-biomarkers
#8
Jahanshir Tavakolizadeh, Kambiz Roshanaei, Arash Salmaninejad, Reza Yari, Javid Sadri Nahand, Hoda Khoshdel Sarkarizi, Seyed Mojtaba Mousavi, Reza Salarinia, Majid Rahmati, Seyed Farshid Mousavi, Ryan Mokhtari, Hamed Mirzaei
Depression is known as one of important psychiatric disorders which could be associated with disability among various populations. Diagnostic and statistical manual of mental disorders, 4th edition (DSM-IV) and international statistical classification of diseases and related health problems (ICD-10) could be used as subjective diagnostic schemes for identification of mental disorders such as depression. Utilization of subjective diagnostic schemes are associated with limitations. Hence, it seems that employing of new diagnosis platforms is required...
December 13, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29227567/the-dog-is-a-model-for-the-study-of-human-hip-dysplasia
#9
Cecilia Pascual-Garrido, Farshid Guilak, Muhammad Farooq Rai, Michael D Harris, Mandi J Lopez, Rory J Todhunter, John C Clohisy
Developmental dysplasia of the hip (DDH) in humans is a common condition that is associated with hip pain, functional limitations, and secondary osteoarthritis (OA). Surgical treatment of DDH has improved in the last decade, allowing excellent outcomes at short- and mid-term follow-up. Still, the etiology, mechanobiology, and pathology underlying this disease are not well understood. A pre-clinical animal model of DDH could help advance the field with a deeper understanding of specific pathways that initiate hip joint degeneration secondary to abnormal biomechanics...
December 11, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29216799/flavonoids-as-potent-allosteric-inhibitors-of-protein-tyrosine-phosphatase-1b-molecular-dynamics-simulation-and-free-energy-calculation
#10
Farshid Zargari, Maryam Lotfi, Omolbanin Shahraki, Zahra Nikfarjam, Jafar Shahraki
Protein tyrosine phosphatase 1B (PTP1B) is a member of the PTP superfamily which is considered to be a negative regulator of insulin receptor (IR) signalling pathway. PTP1B is a promising drug target for the treatment of type 2 diabetes, obesity and cancer. The existence of allosteric site in PTP1B has turned the researcher's attention to an alternate strategy for inhibition of this enzyme. Herein, the molecular interactions between the allosteric site of PTP1B with three non-competitive flavonoids, (MOR), (MOK), and (DPO) have been investigated...
December 7, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/29209174/potential-mechanisms-underlying-inflammation-enhanced-aminoglycoside-induced-cochleotoxicity
#11
REVIEW
Meiyan Jiang, Farshid Taghizadeh, Peter S Steyger
Aminoglycoside antibiotics remain widely used for urgent clinical treatment of life-threatening infections, despite the well-recognized risk of permanent hearing loss, i.e., cochleotoxicity. Recent studies show that aminoglycoside-induced cochleotoxicity is exacerbated by bacteriogenic-induced inflammation. This implies that those with severe bacterial infections (that induce systemic inflammation), and are treated with bactericidal aminoglycosides are at greater risk of drug-induced hearing loss than previously recognized...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29205822/routine-reporting-of-mammographic-density-from-screening-mammograms
#12
Gelareh Farshid
No abstract text is available yet for this article.
December 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29204181/synthesis-and-evaluation-of-antimicrobial-activity-of-cyclic-imides-derived-from-phthalic-and-succinic-anhydrides
#13
Elham Jafari, Najmeh Taghi Jarah-Najafabadi, Ali Jahanian-Najafabadi, Safoora Poorirani, Farshid Hassanzadeh, Sedighe Sadeghian-Rizi
Cyclic imides are a group of compounds which have valuable biological properties including cytotoxic, anti-inflammatory, antibacterial and antifungal activities. In this study, succinic and phthalic anhydrides were treated with glycinamide in pyridine to yield the corresponding amic acids. These amic acids underwent ring closure with acetic anhydride and anhydrous sodium acetate to form cyclic imides. In another procedure, succinic and phthalic anhydrides upon reaction with 2-amino-benzylamine in pyridine gave the corresponding cyclic imides...
December 2017: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29204178/biological-evaluation-docking-and-molecular-dynamic-simulation-of-some-novel-diaryl-urea-derivatives-bearing-quinoxalindione-moiety
#14
Sedighe Sadeghian-Rizi, Ghadamali Ali Khodarahmi, Amirhossein Sakhteman, Ali Jahanian-Najafabadi, Mahboubeh Rostami, Mahmoud Mirzaei, Farshid Hassanzadeh
In this study a series of diarylurea derivatives containing quinoxalindione group were biologically evaluated for their cytotoxic activities using MTT assay against MCF-7 and HepG2 cell lines. Antibacterial activities of these compounds were also evaluated by Microplate Alamar Blue Assay (MABA) against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi), three Gram-positive (Staphylococcus aureus, Bacillus subtilis and Listeria monocitogenes) and one yeast-like fungus (Candida albicans) strain...
December 2017: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29204173/synthesis-characterization-cytotoxic-screening-and-density-functional-theory-studies-of-new-derivatives-of-quinazolin-4-3h-one-schiff-bases
#15
Rezvan Rezaee Nasab, Farshid Hassanzadeh, Ghadam Ali Khodarahmi, Mahmoud Mirzaei, Mahboubeh Rostami, Ali Jahanian-Najaf Abadi
A series of novel derivatives of quinazolinone Schiff bases were synthesized from benzoic acid starting material and evaluated for potential cytotoxic activities against the human breast adenocarcinoma (MCF-7) and the human colon adenocarcinoma (HT-29) cell lines. Compared to the reference drug, these compounds showed good cytotoxic activities against studied cell lines especially compounds 4d and 4e. The ground-state geometries of these compounds (4a-g) were optimized at the B3LYP/6-31G* density functional theory (DFT) level...
December 2017: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29202453/increased-ca2-signaling-through-cav1-2-promotes-bone-formation-and-prevents-estrogen-deficiency-induced-bone-loss
#16
Chike Cao, Yinshi Ren, Adam S Barnett, Anthony J Mirando, Douglas Rouse, Se Hwan Mun, Kyung-Hyun Park-Min, Amy L McNulty, Farshid Guilak, Courtney M Karner, Matthew J Hilton, Geoffrey S Pitt
While the prevalence of osteoporosis is growing rapidly with population aging, therapeutic options remain limited. Here, we identify potentially novel roles for CaV1.2 L-type voltage-gated Ca2+ channels in osteogenesis and exploit a transgenic gain-of-function mutant CaV1.2 to stem bone loss in ovariectomized female mice. We show that endogenous CaV1.2 is expressed in developing bone within proliferating chondrocytes and osteoblasts. Using primary BM stromal cell (BMSC) cultures, we found that Ca2+ influx through CaV1...
November 16, 2017: JCI Insight
https://www.readbyqxmd.com/read/29196867/prevalence-of-haptic-feedback-in-robot-mediated-surgery-a-systematic-review-of-literature
#17
REVIEW
Farshid Amirabdollahian, Salvatore Livatino, Behrad Vahedi, Radhika Gudipati, Patrick Sheen, Shan Gawrie-Mohan, Nikhil Vasdev
With the successful uptake and inclusion of robotic systems in minimally invasive surgery and with the increasing application of robotic surgery (RS) in numerous surgical specialities worldwide, there is now a need to develop and enhance the technology further. One such improvement is the implementation and amalgamation of haptic feedback technology into RS which will permit the operating surgeon on the console to receive haptic information on the type of tissue being operated on. The main advantage of using this is to allow the operating surgeon to feel and control the amount of force applied to different tissues during surgery thus minimising the risk of tissue damage due to both the direct and indirect effects of excessive tissue force or tension being applied during RS...
December 1, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29189979/comparison-of-biophysical-properties-characterized-for-microtissues-cultured-using-microencapsulation-and-liquid-crystal-based-3d-cell-culture-techniques
#18
Chin Fhong Soon, Kian Sek Tee, Soon Chuan Wong, Nafarizal Nayan, Sargunan Sundra, Mohd Khairul Ahmad, Farshid Sefat, Naznin Sultana, Mansour Youseffi
Growing three dimensional (3D) cells is an emerging research in tissue engineering. Biophysical properties of the 3D cells regulate the cells growth, drug diffusion dynamics and gene expressions. Scaffold based or scaffoldless techniques for 3D cell cultures are rarely being compared in terms of the physical features of the microtissues produced. The biophysical properties of the microtissues cultured using scaffold based microencapsulation by flicking and scaffoldless liquid crystal (LC) based techniques were characterized...
November 30, 2017: Cytotechnology
https://www.readbyqxmd.com/read/29184260/topical-effects-of-artemisia-absinthium-ointment-and-liniment-in-comparison-with-piroxicam-gel-in-patients-with-knee-joint-osteoarthritis-a-randomized-double-blind-controlled-trial
#19
Zahra Basiri, Fatemeh Zeraati, Farzaneh Esna-Ashari, Farshid Mohammadi, Keyvan Razzaghi, Malihe Araghchian, Shirin Moradkhani
Background: Pain alleviation and improvement of functional status are the main objectives in the treatment of osteoarthritis. Artemisia absinthium (AA) was used traditionally in reducing pain and inflammation. The aim of the present study was to compare the effects of topical formulations of AA and piroxicam gel (PG) among patients with knee osteoarthritis. Methods: In total, 90 outpatients aged 30-70 years with the diagnosis of primary osteoarthritis in at least one knee were enrolled in a randomized double-blind clinical trial...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29177974/antitumor-activity-of-raloxifene-targeted-poly-styrene-maleic-acid-poly-amide-ether-ester-imide-co-polymeric-nanomicelles-loaded-with-docetaxel-in-breast-cancer-bearing-mice
#20
Saeede Enteshari, Jaleh Varshosaz, Mohsen Minayian, Farshid Hassanzadeh
Purpose Raloxifene (RA) receptors have over-expressed GPER-positive breast cancer tumors. The purpose of this work was to evaluate the antitumor activity and pharmacokinetic behavior of docetaxel (DTX), loaded in RA-targeted nanomicelles, which were designed to overcome a lack of specific distribution and inadequate DTX concentration in tumor tissues, as well as its cytotoxicity and damage to normal tissues. Methods DTX-loaded RA-targeted poly(styrene maleic acid) (SMA)- poly(amide-ether-esterimide)-poly(ethylene glycol) (PAEEI-PEG) nanomicelles were prepared; then, their antitumor activity and survival rate were studied in MC4-L2 tumors induced in BALB/c mice...
November 27, 2017: Investigational New Drugs
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