keyword
https://read.qxmd.com/read/38464604/comparison-of-the-sedative-and-cardiovascular-effects-of-the-combination-of-acepromazine-clonidine-versus-acepromazine-xylazine-in-horses
#1
JOURNAL ARTICLE
Pegah Parhizkar, Rahim Mohammadi, Seyed Mohammad Hashemi-Asl, Ghader Jalilzadeh-Amin, Farshid Sarrafzadeh-Rezaei
The aim of this study was to compare the sedative and cardiovascular effects of the combination of acepromazine-clonidine versus acepromazine-xylazine in horses. Four healthy cross-bred horses were included in the study. They were assigned to two treatments. In treatment I (T1), the animals received xylazine hydrochloride (1.00 mg kg-1 ) in combination with acepromazine maleate (0.05 mg kg-1 ) intravenously (IV). In treatment II (T2), the animals received intra-gastric administration of clonidine (0.002 mg kg-1 ) followed by acepromazine (0...
2024: Veterinary Research Forum
https://read.qxmd.com/read/38464070/distinct-roles-for-ltalpha3-and-ltalpha1beta2-produced-by-b-cells-contribute-to-their-multi-faceted-impact-on-ileitis
#2
Gwendalyn Randolph, Emma Erlich, Rafael Czepielewski, Rachael Field, Taylor Dunning, Leila Saleh, Mark Hoofnagle, Alexei Tumanov, Farshid Guilak, Jonathan Brestoff
B lymphocytes may facilitate chronic inflammation through antibody production or secretion of cytokines, including lymphotoxin (LT)-a 1 b 2 associated with development of lymphoid tissue. Tertiary lymphoid structures (TLS) characterize human and murine ileitis by suppressing outflow from the ileum. Here, we show that B cell-derived secretory IgA protected against ileal inflammation, whereas B cell-derived LTa guarded against ileitis-associated loss of body mass. We initially hypothesized this protection resulted from formation of TLS that suppressed lymphatic outflow and thereby restrained systemic spread of inflammatory signals, but B cell-selective deletion of LTb did not exacerbate weight loss, despite eliminating TLS...
February 26, 2024: Research Square
https://read.qxmd.com/read/38461711/risk-factors-for-neurological-disability-outcomes-in-patients-under-extracorporeal-membrane-oxygenation-following-cardiac-arrest-an-observational-study
#3
JOURNAL ARTICLE
Amir Vahedian-Azimi, Ibrahim Fawzy Hassan, Farshid Rahimi-Bashar, Hussam Elmelliti, Anzila Akbar, Ahmed Labib Shehata, Abdulsalam Saif Ibrahim, Ali Ait Hssain
OBJECTIVES: This study aimed to identify factors associated with neurological and disability outcomes in patients who underwent ECMO following cardiac arrest. METHODS: This retrospective, single-center, observational study included adult patients who received ECMO treatment for in-hospital cardiac arrest (IHCA) or out-of-hospital cardiac arrest (OHCA) between February 2016 and March 2020. Factors associated with neurological and disability outcomes in these patients who underwent ECMO were assessed...
March 9, 2024: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://read.qxmd.com/read/38443610/relative-contributions-of-taxonomic-and-functional-diversity-to-the-assembly-of-plant-communities-hosting-endemic-dianthus-species-in-a-mountain-steppe
#4
JOURNAL ARTICLE
Maryam Behroozian, Simon Pierce, Hamid Ejtehadi, Farshid Memariani, Fahime Rafiee, Mohammad Reza Joharchi
Plant community assembly is the outcome of long-term evolutionary events (evident as taxonomic diversity; TD) and immediate adaptive fitness (functional diversity; FD); a balance expected to shift in favour of FD in 'harsh' habitats under intense selection pressures. We compared TD and FD responses along climatic and edaphic gradients for communities of two species (Dianthus pseudocrinitus and D. polylepis) endemic to the montane steppes of the Khorassan-Kopet Dagh floristic province, NE Iran. 75 plots at 15 sites were used to relate TD and FD to environmental gradients...
March 5, 2024: Scientific Reports
https://read.qxmd.com/read/38438853/prognostic-effects-of-cardiopulmonary-resuscitation-cpr-start-time-and-the-interval-between-cpr-to-extracorporeal-cardiopulmonary-resuscitation-ecpr-on-patient-outcomes-under-extracorporeal-membrane-oxygenation-ecmo-a-single-center-retrospective-observational
#5
JOURNAL ARTICLE
Amir Vahedian-Azimi, Ibrahim Fawzy Hassan, Farshid Rahimi-Bashar, Hussam Elmelliti, Mahmood Salesi, Hazim Alqahwachi, Fatima Albazoon, Anzila Akbar, Ahmed Labib Shehata, Abdulsalam Saif Ibrahim, Ali Ait Hssain
BACKGROUND: The impact of the chronological sequence of events, including cardiac arrest (CA), initial cardiopulmonary resuscitation (CPR), return of spontaneous circulation (ROSC), and extracorporeal cardiopulmonary resuscitation (ECPR) implementation, on clinical outcomes in patients with both out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA), is still not clear. The aim of this study was to investigate the prognostic effects of the time interval from collapse to start of CPR (no-flow time, NFT) and the time interval from start of CPR to implementation of ECPR (low-flow time, LFT) on patient outcomes under Extracorporeal Membrane Oxygenation (ECMO)...
March 5, 2024: BMC Emergency Medicine
https://read.qxmd.com/read/38421023/development-of-a-generic-sample-preparation-method-using-dispersive-liquid-liquid-microextraction-for-the-monitoring-of-leachable-compounds-in-hospital-pharmacy-prepared-prefilled-drug-products
#6
JOURNAL ARTICLE
William Bello, Julian Pezzatti, Serge Rudaz, Farshid Sadeghipour
Performant sample preparation is mandatory in any leachable study to clean and preconcentrate analytes within the sample to offer the best possible extraction recovery as well the best precision for any given substance. The aim consists in developing a sample preparation method for hospital pharmacy-prepared drug products such as long-term storage prefilled syringes, vials and IV bags for the screening of leachable compounds. The Quality Control Laboratory of the Pharmacy of the Lausanne University Hospital (Switzerland) has developed a time- and cost-effective, highly sensitive, robust, and fast method using liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) for the analysis of 205 plastic additives...
February 29, 2024: Analytical Methods: Advancing Methods and Applications
https://read.qxmd.com/read/38417352/evaluation-of-c4d-expression-and-staining-patterns-by-immunohistochemistry-in-renal-biopsy-samples-with-focal-segmental-glomerulosclerosis-and-minimal-change-disease
#7
JOURNAL ARTICLE
Maryam Abedi, Fatemeh Nili, Farshid Dehkhoda, Alireza Abdollahi, Samaneh Salarvand
INTRODUCTION: C4d is an activation product of lectin pathway of complement. Glomerular deposition of C4d is associated with poor prognosis in different types of immune-related glomerulonephritis. The present study was conducted to investigate expression level of C4d and its staining pattern in renal biopsy of patients with focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) by immunohistochemistry method. MATERIALS AND METHODS: In this retrospective cross-sectional study, renal biopsy specimens from 46 samples of MCD, 47 samples of FSGS, and 15 samples without glomerular disease as the controls, were subjected to immunohistochemistry staining with C4d...
February 13, 2024: Annals of Diagnostic Pathology
https://read.qxmd.com/read/38405663/comparison-of-the-efficiency-of-ultrafiltration-precipitation-and-ultracentrifugation-methods-for-exosome-isolation
#8
JOURNAL ARTICLE
Farshid Jaberi Ansari, Hossein Ahmadi Tafti, Amir Amanzadeh, Shahram Rabbani, Mohammad Ali Shokrgozar, Reza Heidari, Javad Behroozi, Hossein Eyni, Vladimir N Uversky, Hossein Ghanbari
Extracellular vesicles (EVs) are enclosed by a lipid-bilayer membrane and secreted by all types of cells. They are classified into three groups: apoptotic bodies, microvesicles, and exosomes. Exosomes play a number of important roles in the intercellular communication and crosstalk between tissues in the body. In this study, we use three common methods based on different principles for exosome isolation, namely ultrafiltration, precipitation, and ultracentrifugation. We use field emission scanning electron microscopy (FESEM) and dynamic light scattering (DLS) analyses for characterization of exosomes...
July 2024: Biochemistry and Biophysics Reports
https://read.qxmd.com/read/38388898/lesson-learned-from-assessing-teachers-and-students-perspectives-regarding-the-quality-of-e-learning-in-medical-education-during-the-pandemic-a-mixed-methods-study
#9
JOURNAL ARTICLE
Nahid Zarifsanaiey, Majid Reza Farrokhi, Zahra Karimian, Sara Hoseini, Farshid Chahartangi, Hadi Raeisi Shahraki
BACKGROUND: The evaluation of e-learning systems ensures the provision of quality training. The goal was to identify the perspectives of teachers and students on e-learning in medical education during the COVID-19 pandemic at Shiraz University of Medical Sciences (SUMS), Iran. METHODS: This study utilized a convergent mixed methods research design with a two-phase approach to collect and analyze data between June and August 2022. In the first stage, a cross-sectional descriptive study was conducted to evaluate the quality of e-learning systems from the perspective of 400 students...
February 22, 2024: BMC Medical Education
https://read.qxmd.com/read/38388222/machine-learning-applications-in-spine-biomechanics
#10
JOURNAL ARTICLE
Farshid Ghezelbash, Amir Hossein Eskandari, Xavier Robert-Lachaine, Shufan Cao, Mehran Pesteie, Zhuohua Qiao, Aboulfazl Shirazi-Adl, Christian Larivière
Spine biomechanics is at a transformation with the advent and integration of machine learning and computer vision technologies. These novel techniques facilitate the estimation of 3D body shapes, anthropometrics, and kinematics from as simple as a single-camera image, making them more accessible and practical for a diverse range of applications. This study introduces a framework that merges these methodologies with traditional musculoskeletal modeling, enabling comprehensive analysis of spinal biomechanics during complex activities from a single camera...
February 1, 2024: Journal of Biomechanics
https://read.qxmd.com/read/38375518/vitamin-d-3-a-promising-antifungal-and-antibiofilm-agent-against-candida-species
#11
JOURNAL ARTICLE
Zahra Kherad, Somayeh Yazdanpanah, Farshid Saadat, Keyvan Pakshir, Kamiar Zomorodian
BACKGROUND AND PURPOSE: Candida species are opportunistic fungal pathogens that cause mild to life-threatening infections in both immunocompetent and immunocompromised populations. The increasing prevalence of drug-resistant Candida species has posed a significant challenge to the management of infections in clinical settings. Therefore, this study aimed to investigate the direct antifungal and antibiofilm effect of vitamin D3 against Candida species. MATERIALS AND METHODS: The antifungal activity of vitamin D3 was evaluated by broth microdilution method based on the Clinical and Laboratory Standard Institute...
June 2023: Current Medical Mycology
https://read.qxmd.com/read/38372420/myths-and-methodologies-understanding-the-health-impact-of-head-down-bedrest-for-the-benefit-of-older-adults-and-astronauts-study-protocol-of-the-canadian-bedrest-study
#12
JOURNAL ARTICLE
Guy Hajj-Boutros, Vita Sonjak, Andréa Faust, Sharmila Balram, Jean-Christophe Lagacé, Philippe St-Martin, Donya Naz Divsalar, Farshid Sadeghian, Teresa Liu-Ambrose, Andrew P Blaber, Isabelle J Dionne, Simon Duchesne, Saija Kontulainen, Olga Theou, José A Morais
Weightlessness during spaceflight can harm various bodily systems, including bone density, muscle mass, strength and cognitive functions. Exercise appears to somewhat counteract these effects. A terrestrial model for this is head-down bedrest (HDBR), simulating gravity loss. This mirrors challenges faced by older adults in extended bedrest and space environments. The first Canadian study, backed by the Canadian Space Agency, Canadian Institutes of Health Research, and Canadian Frailty Network, aims to explore these issues...
February 19, 2024: Experimental Physiology
https://read.qxmd.com/read/38365633/epidemiology-of-substance-and-opium-use-among-adult-residents-of-tehran-a-comprehensive-report-from-tehran-cohort-study-tecs
#13
JOURNAL ARTICLE
Farzad Masoudkabir, Akbar Shafiee, Amirhossein Heidari, Negin Sadat Hosseini Mohammadi, Kiarash Tavakoli, Arash Jalali, Sepehr Nayebirad, Farshid Alaeddini, Soheil Saadat, Ali Vasheghani-Farahani, Saeed Sadeghian, Vicente Artola Arita, Mohamamdali Boroumand, Abbasali Karimi
BACKGROUND: The prevalence and burden of substance and opium use have increased worldwide over the past decades. In light of rapid population changes in Tehran, we aimed to evaluate the prevalence of opium and other substance use among adult residents in Tehran, Iran. METHOD: From March 2016 to March 2019, we utilized data from 8 296 participants in the Tehran Cohort Study recruitment phase (TeCS). We calculated the age-sex-weighted prevalence of substance use and the geographic distribution of substance use in Tehran...
February 16, 2024: BMC Psychiatry
https://read.qxmd.com/read/38360785/automated-detection-of-cervical-spinal-stenosis-and-cord-compression-via-vision-transformer-and-rules-based-classification
#14
JOURNAL ARTICLE
David L Payne, Xuan Xu, Farshid Faraji, Kevin John, Katherine Ferra Pradas, Vahni Vishala Bernard, Lev Bangiyev, Prateek Prasanna
BACKGROUND AND PURPOSE: Cervical spinal cord compression, defined as spinal cord deformity and severe narrowing of the spinal canal in the cervical region, can lead to severe clinical consequences, including intractable pain, sensory disturbance, paralysis, and even death, and may require emergent intervention to prevent negative outcomes. Despite the critical nature of cord compression, no automated tool is available to alert clinical radiologists to the presence of such findings. This study aims to demonstrate the ability of a vision transformer (ViT) model for the accurate detection of cervical cord compression...
February 15, 2024: AJNR. American Journal of Neuroradiology
https://read.qxmd.com/read/38353090/prevalence-of-colonic-polyps-detected-by-colonoscopy-in-symptomatic-patients-and-comparison-between-different-age-groups-what-age-should-be-considered-for-investigation
#15
JOURNAL ARTICLE
Fardad Ejtehadi, Ali Reza Taghavi, Farshid Ejtehadi, Iraj Shahramian, Ramin Niknam, Maryam Moini, Masoud Tahani
<b>Introduction:</b> The Burden of Colorectal cancer (CRC) as one of the most common malignancies is considerable worldwide, with 1.8 million diagnoses each year. Although it is well established that most CRCs arise from colonic polyps, guidelines and recommendations indicate different ages as starting points for endoscopic examination of the colon, either as cancer screening programs or in symptomatic patients. Most standard guidelines adapt the cut-off age of 50. However, this has been challenged by the results of recent studies...
July 11, 2023: Polski Przeglad Chirurgiczny
https://read.qxmd.com/read/38336270/fibrin-clot-fracture-under-cyclic-fatigue-and-variable-rate-loading
#16
JOURNAL ARTICLE
Shiyu Liu, Aram Bahmani, Farshid Ghezelbash, Jianyu Li
Fibrin clot is a of vital class of fibrous materials, governing the mechanical response blood clots. Fracture behavior of fibrin clots under complex physiological load is relevant for hemostasis and thrombosis. But how they fracture under cyclic and variable rate loading has not been reported. Here we conduct cyclic fatigue and monotonic variable rate loading tests on fibrin clots to characterize their fracture properties in terms of fatigue threshold and rate-dependent fracture toughness. We demonstrate that the fracture behavior of fibrin clots is sensitive to the amplitude of cyclic load and the loading rate...
February 7, 2024: Acta Biomaterialia
https://read.qxmd.com/read/38329621/gold-nanoparticles-aunps-decrease-the-viability-of-cervical-cancer-cells-by-inducing-the-bax-gene-and-activating-antioxidant-enzymes
#17
JOURNAL ARTICLE
Noor Alhuda Kamil Shareef, Farshid Zandsalimi, Gholamreza Tavoosidana
BACKGROUND: Cervical Cancer (CC), a leading cause of female mortality worldwide, demonstrates a direct association with high-risk human papillomavirus (HPV) infections. However, not all CC patients exhibit HPV infection, suggesting additional predisposing factors. Recently, disturbances in the oxidant-antioxidant balance have been implicated in CC development. This study explores the impact of gold nanoparticles (AuNPs) on the survival and antioxidant capacity of HeLa cells, aiming to contribute to novel CC therapy approaches...
February 8, 2024: Molecular Biology Reports
https://read.qxmd.com/read/38322859/evaluating-urban-environmental-quality-using-multi-criteria-decision-making
#18
JOURNAL ARTICLE
Hassan Mahmoudzadeh, Asghar Abedini, Farshid Aram, A Mosavi
In the urban environment, the quality refers to the capacity that provides and fulfills the material and spiritual needs of inhabitants. In order to improve the quality of urban life and standard of living for their citizens, planners and managers strive to raise Urban Environmental Quality. The objective of this study is to evaluate the quality of urban environment through the spatial analysis of a multi-criteria decision making (MCDM) method utilizing CRITIC. This research is conducted in district 4 and district 2 of the Tabriz Metropolis Municipality...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38308792/d-limonene-inhibits-peritoneal-adhesion-formation-in-rats-via-anti-inflammatory-anti-angiogenic-and-antioxidative-effects
#19
JOURNAL ARTICLE
Ali Razazi, Ali Kakanezhadi, Abbas Raisi, Behnam Pedram, Omid Dezfoulian, Farshid Davoodi
The aim of this research was to investigate the effects of D-limonene on decreasing post-operative adhesion in rats and to understand the mechanisms involved. Peritoneal adhesions were induced by creating different incisions and excising a 1 × 1 cm section of the peritoneum. The experimental groups included a sham group, a control group in which peritoneal adhesions were induced without any treatment, and two treatment groups in which animals received D-limonene with dosages of 25 and 50 mg/kg after inducing peritoneal adhesions...
February 3, 2024: Inflammopharmacology
https://read.qxmd.com/read/38300194/comparison-of-the-effects-of-aromatherapy-with-damask-rose-and-chamomile-essential-oil-on-preoperative-pain-and-anxiety-in-emergency-orthopedic-surgery-a-randomized-controlled-trial
#20
JOURNAL ARTICLE
Farshid Bahrami, Nasrin Hanifi, Abbas Mardani
PURPOSE: Patients who are awaiting emergency surgery experience high levels of anxiety and pain. This study aimed to compare the effects of aromatherapy with damask rose and chamomile essential oil on the preoperative pain and anxiety associated with emergency orthopedic surgery. DESIGN: A parallel-group randomized controlled design was used. METHODS: Ninety participants were selected and randomly assigned to three groups: the damask rose group (n = 30), the chamomile group (n = 30), and the control group (n = 30)...
January 31, 2024: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
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