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https://www.readbyqxmd.com/read/29227139/phenotypic-hip-and-elbow-dysplasia-trends-in-rottweilers-and-labrador-retrievers-in-south-africa-2007-2015-are-we-making-progress
#1
Robert M Kirberger
Canine hip and elbow dysplasia are major orthopaedic problems prevalent the world over, and South Africa is no exception. Hip and elbow dysplasia phenotypic status is certified by a number of different radiographic schemes in the world. South Africa uses the Fédération Cynologique Internationale system to certify hips, and the International Elbow Working Group scheme to certify elbows. One way of reducing these often crippling conditions is by selective breeding using only dogs with no or marginal dysplastic joints...
November 22, 2017: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/29223595/modulation-of-cartilage-s-response-to-injury-can-chondrocyte-apoptosis-be-reversed
#2
REVIEW
Ippokratis Pountos, Peter V Giannoudis
Osteoarthritis is characterized by a chronic, progressive and irreversible degradation of the articular cartilage associated with joint inflammation and a reparative bone response. More than 100 million people are affected by this condition worldwide with significant health and welfare costs. Our available treatment options in osteoarthritis are extremely limited. Chondral or osteochondral grafts have shown some promising results but joint replacement surgery is by far the most common therapeutic approach. The difficulty lies on the limited regeneration capacity of the articular cartilage, poor blood supply and the paucity of resident progenitor stem cells...
December 2017: Injury
https://www.readbyqxmd.com/read/29221499/an-unusual-osteoma-in-the-mandibular-condyle-and-the-successful-replacement-of-the-temporomandibular-joint-with-a-custom-made-prosthesis-a-case-report
#3
Natalia Tavares de Souza, Renan Carlos Lopes Cavalcante, Maria Aparecida de Albuquerque Cavalcante, Wagner Hespanhol, Marcello Rodrigues de Oliveira, Dennis de Carvalho Ferreira, Thais Machado de Carvalho Coutinho, Lucio Souza Gonçalves
BACKGROUND: An osteoma is a benign tumor of bone with unknown etiology and is considered rare, mostly restricted to the craniofacial skeleton. CASE PRESENTATION: This case report describes an uncommon condylar osteoma in a 67 years old white female patient with laterognathism to the left side, limited mouth opening, aesthetic change and pain associated with the right temporomandibular joint (TMJ). The histopathological examination confirmed osteoma. The lesion was surgically excised and immediate reconstruction was carried out using a custom-made total TMJ prosthesis...
December 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29218309/kinematic-changes-during-prolonged-fast-walking-in-old-and-young-adults
#4
Camila Fonseca Oliveira, Edgar Ramos Vieira, Filipa Manuel Machado Sousa, João Paulo Vilas-Boas
Walking biomechanics is known to be influenced by speed. However, most of the research examining the effects of walking speed and gait characteristics has been conducted after a fast-walking task, neglecting the changes that may occur during the task. The aim of the present study was to determine the impact of fast-walking over time on kinematics in young and old adults. Twenty-seven young adults (26.6 ± 6.0 years) and 23 old adults (71.0 ± 5.6 years) walked at 70% of their maximum heart rate for 20 min or until exhaustion, and the effects of fast-walking on temporospatial parameters and on angular kinematics were analyzed during the activity...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29215692/chondroid-tenosynovial-giant-cell-tumor-of-the-temporomandibular-joint-a-rare-case-report
#5
Ana Lia Anbinder, Barbara Maria Corrêa Geraldo, Rubens Guimarães, Débora Lima Pereira, Oslei Paes de Almeida, Yasmin Rodarte Carvalho
Tenosynovial giant cell tumor of diffuse type (TGCT-d) or pigmented villonodular synovitis (PVNS) is a locally aggressive lesion that mostly affects the joints of long bones. Chondroid tenosynovial giant cell tumor (CTGCT) or PVNS with chondroid metaplasia is a rare distinct subset of synovial tumors that has a predilection for the TMJ. We report a rare case of CTGCT in the TMJ, initially misdiagnosed as temporomandibular disorder (TMD). A 51-year-old woman was referred to the surgeon with the chief complaint of TMJ pain for 5 years and a past history of an unsuccessful TMD treatment...
September 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29215571/application-of-the-superelastic-niti-spring-in-ankle-foot-orthosis-afo-to-create-normal-ankle-joint-behavior
#6
Amirhesam Amerinatanzi, Hashem Zamanian, Narges Shayesteh Moghaddam, Ahmadreza Jahadakbar, Mohammad Elahinia
Hinge-based Ankle Foot Orthosis (HAFO) is one of the most common non-surgical solutions for the foot drop. In conventional HAFOs, the ankle joint is almost locked, and plantar flexion is restricted due to the high stiffness of the hinge mechanism. This often leads to a rigid walking gate cycle, poor muscle activity, and muscle atrophy. Since the ankle torque-angle loop has a non-linear profile, the use of a superelastic NiTi spring within the hinge, due to its nonlinear behavior, could recreate a close-to-normal stiffness of the normal ankle joint, which, in turn, could create a more natural walk...
December 7, 2017: Bioengineering
https://www.readbyqxmd.com/read/29215557/indoors-locality-positioning-using-cognitive-distances-and-directions
#7
Yankun Wang, Hong Fan, Ruizhi Chen
Spatial relationships are crucial to spatial knowledge representation, such as positioning localities. However, minimal attention has been devoted to positioning localities indoors with locality description. Distance and direction relations are generally used when positioning localities, namely, translating descriptive localities into spatially explicit ones. We propose a joint probability function to model locality distribution to address the uncertainty of positioning localities. The joint probability function consists of distance and relative direction membership functions...
December 7, 2017: Sensors
https://www.readbyqxmd.com/read/29215327/factors-modifying-the-radon-related-lung-cancer-risk-at-low-exposures-and-exposure-rates-among-german-uranium-miners
#8
M Kreuzer, C Sobotzki, M Schnelzer, N Fenske
It is still not fully understood whether and how factors such as time, age and smoking modify the relationship between lung cancer and radon at low exposures and exposure rates. Improved knowledge is necessary for the dose conversion of radon in working level month (WLM) into effective dose, as currently discussed by the International Commission on Radiological Protection (ICRP). An update of the German uranium miner cohort study (n = 58,974 men) with a 10-year extension of mortality follow-up (1946-2013) was used to further examine this issue...
December 7, 2017: Radiation Research
https://www.readbyqxmd.com/read/29202560/the-use-of-hyaluronic-acid-in-the-treatment-of-shoulder-capsulitis-a-systematic-review
#9
R Papalia, A Tecame, G Vadalà, F Russo, M Perna, G Papalia, F Bressi, S Sterzi, V Denaro
Adhesive capsulitis (AC) is a common pathological condition of the shoulder characterized by painful restriction of range of motion (ROM) of the glenohumeral joint. Currently, no consensus has been reached regarding the best treatment. Hyaluronic acid (HA) injection is a safe procedure that can result in significant improvement in active and passive ROM, alleviating pain and improving shoulder function. We systematically reviewed current literature in order to evaluate the best evidence about the effectiveness of intra-articular HA injection for the treatment of primary AC...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29202351/psoas-abscess-masquerading-as-a-prosthetic-hip-infection-a-case-report
#10
Muhammad Atif, Azeem Tariq Malik, Shahryar Noordin
INTRODUCTION: Psoas abscess is an unusual condition and is defined as a collection of pus in the iliopsoas compartment. Due to the unique anatomy of psoas muscle it forms a conduit for spread of infection from upper part of body to hip joint in neglected cases. CASE PRESENTATION: A 67year old lady presented with left groin pain for three weeks. She underwent an uncemented unipolar hemiarthoplasty eight years back. Currently, she developed fever and was unable to do any active left hip range of motion...
December 1, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29198369/a-practical-step-length-algorithm-using-lower-limb-angular-velocities
#11
E Allseits, V Agrawal, J Lučarević, R Gailey, I Gaunaurd, C Bennett
The use of Inertial Measurement Units (IMUs) for spatial gait analysis has opened the door to unconstrained measurements within the home and community. Bandwidth, cost limitations, and ease of use has historically restricted the number and location of sensors worn on the body. In this paper, we describe a four-sensor configuration of IMUs placed on the shanks and thighs that is sufficient to provide an accurate measure of temporal gait parameters, spatial gait parameters, and joint angle dynamics during ambulation...
November 16, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29188140/forelimb-muscle-and-joint-actions-in-archosauria-insights-from-crocodylus-johnstoni-pseudosuchia-and-mussaurus-patagonicus-sauropodomorpha
#12
Alejandro Otero, Vivian Allen, Diego Pol, John R Hutchinson
Many of the major locomotor transitions during the evolution of Archosauria, the lineage including crocodiles and birds as well as extinct Dinosauria, were shifts from quadrupedalism to bipedalism (and vice versa). Those occurred within a continuum between more sprawling and erect modes of locomotion and involved drastic changes of limb anatomy and function in several lineages, including sauropodomorph dinosaurs. We present biomechanical computer models of two locomotor extremes within Archosauria in an analysis of joint ranges of motion and the moment arms of the major forelimb muscles in order to quantify biomechanical differences between more sprawling, pseudosuchian (represented the crocodile Crocodylus johnstoni) and more erect, dinosaurian (represented by the sauropodomorph Mussaurus patagonicus) modes of forelimb function...
2017: PeerJ
https://www.readbyqxmd.com/read/29186089/correlation-between-methylenetetrahydrofolate-reductase-mthfr-c677t-polymorphisms-and-pemetrexed-chemotherapy-efficacy-toxicity-in-non-squamous-non-small-cell-lung-cancer
#13
Gaochen Lan, Lin Lin, Xiong Chen, Libin Chen, Xi Chen
BACKGROUND In the present study, we aimed to retrospectively analyze the correlation between toxicity of pemetrexed (PEM) chemotherapy and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms in patients with advanced non-squamous non-small cell lung cancer (non-sq NSCLC). MATERIAL AND METHODS We used polymerase chain reaction, gene scanning, and restriction fragment length polymorphism to analyze MTHFR C677T in 51 patients with advanced non-sq NSCLC. The patients received chemotherapies with single-agent PEM (monotherapy group) or with PEM combined with cisplatin (joint group)...
November 29, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29182550/evolution-of-tandem-repeat-satellite-sequences-in-two-closely-related-caenorhabditis-species-diminution-of-satellites-in-hermaphrodites
#14
Juan A Subirana, Xavier Messeguer
The availability of the genome sequence of the unisexual (male-female) Caenorhabditis nigoni offers an opportunity to compare its non-coding features with the related hermaphroditic species Caenorhabditis briggsae; to understand the evolutionary dynamics of their tandem repeat sequences (satellites), as a result of evolution from the unisexual ancestor. We take advantage of the previously developed SATFIND program to build satellite families defined by a consensus sequence. The relative number of satellites (satellites/Mb) in C...
November 28, 2017: Genes
https://www.readbyqxmd.com/read/29181188/intra-articular-osteochondroma-of-the-posteroinferior-femoral-neck-associated-with-hip-joint-osteochondromatosis-a-case-report
#15
Sung Il Wang, Eun Hae Park, Sun Jung Yoon, Jung Ryul Kim
Osteochondromas are usually extra-articular lesions originating from the metaphysis of long bones. Intra-articular osteochondromas may also occur, causing pain and discomfort and restricting the range of motion. Osteochondromas of the femoral neck are intra-articular lesions that are difficult to access for surgical resection, particularly when located posteriorly. We herein present a rare case of an intra-articular osteochondroma involving the posteroinferior aspect of the femoral neck associated with secondary synovial osteochondromatosis (SOC) of the hip joint in a 25-year-old woman...
November 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29175715/manual-therapy-for-plantar-heel-pain
#16
REVIEW
Yosefa Pollack, Anat Shashua, Leonid Kalichman
BACKGROUND: Manual therapy employed in the treatment of plantar heel pain includes joint or soft tissue mobilizations. Efficacy of these methods is still under debate. AIMS: To determine whether manual therapy, consisting of deep massage, myofascial release or joint mobilization is effective in treating plantar heel pain. METHODS: A critical review of all available studies with an emphasis on randomized controlled trials (RCTs) was performed...
August 5, 2017: Foot
https://www.readbyqxmd.com/read/29161604/ecological-effects-and-potential-risks-of-the-water-diversion-project-in-the-heihe-river-basin
#17
Mengmeng Zhang, Shuai Wang, Bojie Fu, Guangyao Gao, Qin Shen
To curb the severe ecological deterioration in the lower Heihe River Basin (HRB) in northwest China, a water diversion project was initiated in 2000. A comprehensive analysis of the ecological effects and potential risks associated with the project is needed. We assessed the hydrological and ecological achievements, and also analyzed the potential problems after the project was completed. We found that since the project began the hydrological regime has changed, with more than 57.82% of the upstream water being discharged to the lower reaches on average...
November 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29160024/a-conceptual-framework-for-understanding-the-perspectives-on-the-causes-of-the-science-practice-gap-in-ecology-and-conservation
#18
Diana Bertuol-Garcia, Carla Morsello, Charbel N El-Hani, Renata Pardini
Applying scientific knowledge to confront societal challenges is a difficult task, an issue known as the science-practice gap. In Ecology and Conservation, scientific evidence has been seldom used directly to support decision-making, despite calls for an increasing role of ecological science in developing solutions for a sustainable future. To date, multiple causes of the science-practice gap and diverse approaches to link science and practice in Ecology and Conservation have been proposed. To foster a transparent debate and broaden our understanding of the difficulties of using scientific knowledge, we reviewed the perceived causes of the science-practice gap, aiming to: (i) identify the perspectives of ecologists and conservation scientists on this problem, (ii) evaluate the predominance of these perspectives over time and across journals, and (iii) assess them in light of disciplines studying the role of science in decision-making...
November 20, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/29158907/chikungunya-outbreak-in-delhi-india-2016-report-on-coinfection-status-and-comorbid-conditions-in-patients
#19
N Kaur, J Jain, A Kumar, M Narang, M K Zakaria, A Marcello, D Kumar, R Gaind, S Sunil
Chikungunya fever is a major public health issue in India affecting billions. After 2010, the infection was in a decline until in 2016, when a massive outbreak affected the country. In this report, we present serologic and molecular investigations of 600 patient samples for chikungunya and dengue viruses along with clinical and comorbidity features. We recruited 600 patients during this outbreak and evaluated them for chikungunya and dengue virus antibodies and virus RNA through IgM, NS1 antigen and quantitative real-time PCR (qPCR)...
November 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/29153236/nonsurgical-management-of-pediatric-temporomandibular-joint-dysfunction
#20
REVIEW
Steven John Scrivani, Shehryar Nasir Khawaja, Paula Furlan Bavia
Temporomandibular disorders (TMD) are a subgroup of craniofacial pain problems involving the temporomandibular joint (TMJ), masticatory muscles, and associated head and neck musculoskeletal structures. These disorders are subclassified into TMJ articular disorders and masticatory muscle disorders. Patients with TMD most commonly present with pain, restricted or asymmetric mandibular motion, and TMJ sounds during mandibular movements. The prevalence tends to increase with age. Management of TMJ articular disorders consists of a combination of patient education, home-care plan, biobehavioral therapy, physical therapy, orthotic jaw appliance therapy, pharmacotherapy, and/or surgery...
February 2018: Oral and Maxillofacial Surgery Clinics of North America
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