keyword
https://read.qxmd.com/read/38546266/enhanced-thermoelectric-performance-of-a-wide-bandgap-twisted-heterostructure-of-graphene-and-boron-nitride
#21
JOURNAL ARTICLE
Naveen Kumar, Chandan Bera
The manipulation of the relative twist angle between consecutive layers in two-dimensional (2D) materials dramatically modulates their electronic characteristics. Twisted bilayer graphene (tblg) and twisted boron nitride (tBN) exhibit Moiré patterns that have the potential to revolutionize various fields, from electronics to quantum materials. Here, the electronic and thermoelectric properties of 21.8° tblg and 21.8° tBN and a 21.8° twisted graphene/boron nitride (Gr/BN) heterostructure were investigated using density functional theory and Boltzmann transport theory...
March 28, 2024: Nanoscale
https://read.qxmd.com/read/38546234/recognition-of-glaucomatous-fundus-images-using-machine-learning-methods-based-on-optic-nerve-head-topographic-features
#22
JOURNAL ARTICLE
Chao-Wei Wu, Tzu-Yu Huang, Yeong-Cheng Liou, Shih-Hsin Chen, Kwou-Yeung Wu, Han-Yi Tseng
PURPOSE: The aim was to compare the effectiveness of clinical discriminant rules and machine learning classifiers in identifying glaucomatous fundus images based on optic disc topographic features. DESIGN: Retrospective case-control study. METHODS: The study used a total of 800 fundus images, half of which were glaucomatous cases and the other half non- glaucomatous cases obtained from an open database and clinical work. The images were randomly divided into training and testing sets with equal numbers of glaucomatous and non-glaucomatous images...
March 29, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38546007/high-valence-w-6-ions-boost-cr-2-activity-in-crwo-4-for-ideal-water-oxidation
#23
JOURNAL ARTICLE
Chanseok Kim, Dasom Jeon, Nayeong Kim, Jungki Ryu, Jun Hee Lee
Electrocatalytic activity of multi-valence metal oxides for oxygen evolution reaction (OER) arises from various interactions among the constituent metal elements. Although the high-valence metal ions attract recent attentions due to the interactions with their neighboring 3d transition metal catalytic center, atomic-scale explanations for the catalytic efficiencies are still lacking. Here, by employing density functional theory predictions and experimental verifications, unprecedented electronic isolation of the catalytic 3d center (M2+ ) induced by the surrounding high-valence ions such as W6+ is discovered in multivalent oxides MWO4 (M = Ti, V, Cr, Mn, Fe, Co, Ni, Cu, and Zn)...
March 28, 2024: Small
https://read.qxmd.com/read/38545891/soft-nanofluidic-machinery
#24
REVIEW
Zhiping Xu
Soft devices integrating flexible structures and versatile material functionalities offer platform technologies for the healthcare, information, and communication industries. The flexibility can be achieved by constructing devices from low-dimensional nanostructures or nanoporous soft materials. By pushing the limits of fabrication and structuring down to the nanometer and Ångstrom scales, nanofluidics with extreme spatial confinement has recently been actively explored for energy-, environment-, and human-friendly device applications as alternative solutions to electronics and mechanotronics...
March 28, 2024: ACS Nano
https://read.qxmd.com/read/38545784/evaluation-of-plasma-biomarkers-for-causal-association-with-peripheral-artery-disease
#25
JOURNAL ARTICLE
Pranav Sharma, Derek Klarin, Benjamin F Voight, Philip S Tsao, Michael G Levin, Scott M Damrauer
BACKGROUND: Hundreds of biomarkers for peripheral artery disease (PAD) have been reported in the literature; however, the observational nature of these studies limits causal inference due to the potential of reverse causality and residual confounding. We sought to evaluate the potential causal impact of putative PAD biomarkers identified in human observational studies through genetic causal inference methods. METHODS: Putative circulating PAD biomarkers were identified from human observational studies through a comprehensive literature search based on terms related to PAD using PubMed, Cochrane, and Embase...
March 28, 2024: Arteriosclerosis, Thrombosis, and Vascular Biology
https://read.qxmd.com/read/38545766/the-value-of-nerve-ultrasound-to-diagnose-and-follow-up-the-multifocal-neurolyphomatosis-in-the-upper-limb-case-report-and-literature-review
#26
Nan Zhuang, Lu Xie, Dongsheng Liu, HaiQin Xie
INTRODUCTION: Neurolymphomatosis (NL) is a rare disease. Ultrasound (US) plays a crucial role in diagnosing and following up the NL. CASE PRESENTATION: A 59-year-old man was hospitalized with acute pain in the left upper extremity. Ultrasound revealed segmental swelling of multiple nerves around his left elbow with abundant blood flow signals. Contrast-Enhanced Ultrasound (CEUS) showed a rapid, complete and homogenous enhancement in the nerve lesions in the early arterial phase...
2024: Current medical imaging
https://read.qxmd.com/read/38545741/redundant-nerve-roots-on-magnetic-resonance-imaging-can-predict-ongoing-denervation-in-patients-with-lumbar-spinal-stenosis
#27
JOURNAL ARTICLE
Seoyeong Park, Sung Hwan Hong, Sun Gun Chung, Keewon Kim
INTRODUCTION/AIMS: Redundant nerve roots (RNRs) are abnormally elongated and tortuous nerve roots that develop secondary to degenerative spinal stenosis. RNRs have been associated with poorer clinical outcomes after decompression surgery; however, studies on their clinical characteristics are limited. This study aimed to investigate the association between RNRs and denervation potentials, that is, abnormal spontaneous activity (ASA), on electromyography. METHODS: We retrospectively reviewed data of patients who underwent an electrodiagnostic study of the lower extremities between January 2020 and March 2023...
March 28, 2024: Muscle & Nerve
https://read.qxmd.com/read/38545735/early-detection-of-nasopharyngeal-carcinoma-through-machine-learning-driven-prediction-model-in-a-population-based-healthcare-record-database
#28
JOURNAL ARTICLE
Jeng-Wen Chen, Shih-Tsang Lin, Yi-Chun Lin, Bo-Sian Wang, Yu-Ning Chien, Hung-Yi Chiou
OBJECTIVE: Early diagnosis and treatment of nasopharyngeal carcinoma (NPC) are vital for a better prognosis. Still, because of obscure anatomical sites and insidious symptoms, nearly 80% of patients with NPC are diagnosed at a late stage. This study aimed to validate a machine learning (ML) model utilizing symptom-related diagnoses and procedures in medical records to predict nasopharyngeal carcinoma (NPC) occurrence and reduce the prediagnostic period. MATERIALS AND METHODS: Data from a population-based health insurance database (2001-2008) were analyzed, comparing adults with and without newly diagnosed NPC...
April 2024: Cancer Medicine
https://read.qxmd.com/read/38545664/pediatric-performance-based-outcome-measures-for-upper-extremity-function-a-scoping-review-and-linking-to-the-international-classification-of-functioning-disability-and-health
#29
JOURNAL ARTICLE
Caroline Elfassy, Clarice Ribeiro Soares Araújo, Tessah Dunn, Sarah Cachecho, Rose Elekanachi, Johanne Higgins, Laurie Snider, Noemi Dahan-Oliel
Background. Performance-based outcome measures (PBOMs) are objective measures that assess physical capacity or performance in specific tasks or movements. Purpose. 1) to identify which PBOMs are most frequently reported to evaluate upper extremity (UE) function in pediatric rehabilitation 2) to determine the link between constructs of the ICF and meaningful concepts extracted from each identified PBOM. Methods. Pediatric UE PBOMs were searched in four databases. The selection of outcome measures included an initial title and abstract screening, followed by full-text review of the articles to be included based on identified selection criteria...
March 28, 2024: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://read.qxmd.com/read/38545602/long-term-effects-of-mobile-exoneuromusculoskeleton-enms-assisted-self-help-telerehabilitation-after-stroke
#30
JOURNAL ARTICLE
Wanyi Qing, Ching-Yi Nam, Harvey Man-Hok Shum, Marko Ka-Leung Chan, King-Pong Yu, Serena Sin-Wah Ng, Bibo Yang, Xiaoling Hu
Investigation on long-term effects of robot-assisted poststroke rehabilitation is challenging because of the difficulties in administration and follow-up of individuals throughout the process. A mobile hybrid neuromuscular electrical stimulation (NMES)-robot, i.e., exoneuromusculoskeleton (ENSM) was adopted for a single-group trial to investigate the long-term effects of the robot-assisted self-help telerehabilitation on upper limb motor function after stroke. Twenty-two patients with chronic stroke were recruited to attend a 20-session telerehabilitation program assisted by the wrist/hand module of the ENMS (WH-ENMS)...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38545594/single-stage-free-flap-reconstruction-following-extremity-sarcoma-resection-a-regional-cancer-center-experience
#31
JOURNAL ARTICLE
Chandra Kumar Krishnan, Vishnu Ramanujan, Viswamadesh Ramachandran, Narayanaswamy Kathiresan, Anand Raja
Surgery remains mainstay modality of treatment of STS of extremity. In majority of patients, primary closure is possible following surgical resection of the tumor. Primary closure of wound may not be feasible in tumors with large area of skin involvement and sometimes following a whoops procedure. We analyzed postoperative complications and oncological outcomes in patients who underwent free flap reconstruction. Thirty-seven patients who required a free flap for reconstruction of the defect following resection of the STS were included in the study...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38545590/prediction-of-recurrence-free-and-overall-survival-in-retroperitoneal-well-differentiated-and-dedifferentiated-liposarcoma-after-surgery
#32
JOURNAL ARTICLE
Alexander Yu Volkov, Sergey N Nered, Nikolay A Kozlov, Ivan S Stilidi, Peter P Arhiri, Elena Yu Antonova
This study was aimed at creating an effective model for predicting the course of the disease in retroperitoneal well-differentiated (WDLPS) and dedifferentiated (DDLPS) liposarcomas after surgery. The study included 111 patients with WDLPS and 74 patients with DDLPS. We developed a methodology for stratification of patients into prognostic groups. Overall survival (OS) and recurrence-free survival (RFS) were analyzed in accordance with it. The highest OS was achieved in the group "favorable prognosis," while the shortest OS was in the group "extremely poor prognosis" ( p  < 0...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38545588/impact-of-level-of-surgery-on-the-functional-outcomes-in-patients-with-lower-extremity-bone-tumors-undergoing-amputation-versus-limb-salvage-surgery
#33
JOURNAL ARTICLE
Ravi Arjunan, Anvesh Dharanikota, Ramachandra Chowdappa, Syed Althaf, Ashwathappa Dasappa, Naveen S Shetty
Limb salvage surgery is the preferred treatment for bone tumors in the current surgical practice. The aim of this study was to compare the functional outcomes between amputation and limb salvage surgery based on the level of surgery at two levels: knee and hip. A single institutional analysis of 137 patients with lower extremity bone tumors was done between 2014 and 2020. Eighty-seven patients treated with amputation were compared with 50 patients treated with limb salvage surgery based on following variables: age, gender, histology, anatomic site, and MSTS score...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38545586/major-nerve-resections-in-extremity-soft-tissue-sarcomas-functional-and-oncological-outcomes
#34
JOURNAL ARTICLE
Ranganath Ratnagiri, Megha S Uppin, Shantveer G Uppin, Rajshekar Shantappa
Soft tissue sarcomas form 1% of all cancers and are rare. The lower limb is one of the commonest sites of sarcoma, with the thigh accounting for the majority of these tumors. Large tumors abut the neurovascular bundles both anteriorly and in the hamstring compartment. Nerve involvement, especially the major nerves such as the femoral and the sciatic, by these tumors, was considered to be an absolute contraindication for limb salvage procedures. We present our data of major nerve resection without amputation, in an attempt to demonstrate the possibility of equivalent functional and oncological outcomes in these rare tumors...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38545580/clinico-demographic-profile-of-soft-tissue-sarcoma-5-year-experience-from-a-tertiary-care-centre-of-eastern-india
#35
JOURNAL ARTICLE
Linkon Biswas, Anindita Ray, Sumitava De, Koustav Biswas, Srikrishna Mandal
Soft tissue sarcomas (STS) are a diverse group of malignant mesenchymal neoplasm.But, due to their low prevalence, very little data is available worldwide as well as in India regarding their clinico-epidemiological pattern.In this study we analysed the clinico-demographic profile of STS patients attending a tertiary care centre of Eastern India over the last 5 years. We analyzed the prospectively maintained database of a tertiary care centre of West Bengal in Eastern India, and collected the data regarding the demography, clinical profile, pathology and treatment of STS patients who attended our OPD between 2017-2021...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38545577/extremity-high-grade-sarcomas-in-elderly-patients-are-they-candidates-for-surgery-experience-in-a-sarcoma-referral-center
#36
JOURNAL ARTICLE
Daniel Escobar-Mendiola, Lydia Mediavilla-Santos, Rubén Pérez-Mañanes, Miguel Cuervo-Dehesa, Javier Vaquero-Martin, José Calvo-Haro
The number of elderly patients diagnosed with cancer is increasing. However, knowledge regarding cancer in elderly patients is very scarce. The aim of this study is to analyze the differences in management and outcomes of high-grade extremity sarcomas between elderly and middle-aged patients. Two cohorts were made (> 70 and 30/50 years old) among patients treated in a multidisciplinary unit of a national reference center between 2011 and 2017 with a minimum of 2 years of follow-up. The management and outcomes between these two cohorts were compared...
March 2024: Indian Journal of Surgical Oncology
https://read.qxmd.com/read/38545552/diuretic-drug-utilization-in-neonates-a-french-prescription-database-analysis
#37
JOURNAL ARTICLE
Silvia Iacobelli, Simon Lorrain, Ezira Rabe, Béatrice Gouyon, Jean-Bernard Gouyon, Francesco Bonsante
Background: The use of diuretics is extremely common in infants cared for in neonatal wards, despite the lack of proven efficacy for many conditions. The main objective of this study was to assess the rate of diuretics exposure in a multicenter French cohort. The secondary objectives were to describe the evolution of this exposure over time, the indications, the prescription practices, and the exposure rates among centers. Methods: An observational study was conducted in 40 Level 3 French neonatal intensive care units using the same computerized order-entry system...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38545482/characterization-of-asciminib-resistant-philadelphia-chromosome-positive-cells
#38
JOURNAL ARTICLE
Seiichi Okabe, Mitsuru Moriyama, Akihiko Gotoh
BACKGROUND: Asciminib is approved for treating patients with chronic-phase chronic myeloid leukemia who were previously treated with two or more tyrosine kinase inhibitors or those with T315I mutation. However, the mechanisms underlying asciminib resistance remain unclear. METHODS: In this study, we established a new asciminib-resistant cell line. We examined BCR::ABL1 gene mutation analysis and the effects of conventional chronic myelogenous leukemia inhibitors...
April 2024: World Journal of Oncology
https://read.qxmd.com/read/38545470/dna-damage-induced-apoptosis-suppressor-triggers-progression-and-stemness-of-glioma-by-enhancing-lymphoid-enhancer-binding-factor-1-expression
#39
JOURNAL ARTICLE
You Lin Chen, Yi Liu, Yan Xu, An Qiang Yang, Gui Jie Chen, Jin Shan Xing, Hong Wei Su, Li Shang Liao
BACKGROUND: DNA damage-induced apoptosis suppressor (DDIAS) has recently been discovered to induce cancer progression, but its functions and mechanisms in glioma have not been well studied. METHODS: DDIAS expression in glioma tissues was analyzed by the Gene Expression Profiling Interactive Analysis server (GEPIA) and the Gene Expression database of Normal and Tumor tissue 2 (GENT2) databases. The role of DDIAS in glioma progression was studied by short hairpin RNA (shRNA) targeting DDIAS...
April 2024: World Journal of Oncology
https://read.qxmd.com/read/38545442/modelling-the-unexpected-dynamics-of-covid-19-in-manaus-brazil
#40
JOURNAL ARTICLE
Daihai He, Yael Artzy-Randrup, Salihu S Musa, Tiago Gräf, Felipe Naveca, Lewi Stone
In late March 2020, SARS-CoV-2 arrived in Manaus, Brazil, and rapidly developed into a large-scale epidemic that collapsed the local health system and resulted in extreme death rates. Several key studies reported that ∼76% of residents of Manaus were infected (attack rate AR≃76%) by October 2020, suggesting protective herd immunity had been reached. Despite this, an unexpected second wave of COVID-19 struck again in November and proved to be larger than the first, creating a catastrophe for the unprepared population...
June 2024: Infectious Disease Modelling
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