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https://www.readbyqxmd.com/read/28214395/ossified-dysraphic-hamartoma-with-lipomyelocoele-lipomyelomeningocoele-a-rare-radiological-entity
#1
Sudha Bindu Tirumani, Raghavendra Prasad, Vijaya Kumari Mudunoor, Suman Chandra Aemjal, Harika Tirumani, Saurabh Rohatgi
Traditionally the presence of fat in closed spinal dysraphism has been referred to as spinal lipoma. Recent reports suggest that these spinal lesions are better described as spinal hamartomas due to the unencapsulated and infiltrating nature of the fat and presence of other heterotopic soft tissue. The presence of ossified bone in spinal hamartomas referred to as ossified dysraphic hamartoma, is extremely rare with only three case reports in literature, all associated with lipomyeloceles, none with lipomyelomeningoceles...
January 31, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28214199/primary-acinic-cell-carcinoma-of-the-lung-with-psammoma-bodies-a-case-report-and-review-of-literature
#2
Xiu-Peng Zhang, Gui-Yang Jiang, Qing-Fu Zhang, Hong-Tao Xu, Qing-Chang Li, En-Hua Wang
Salivary gland-type tumors are rare in the lung. Primary acinic cell carcinoma of the lung is extremely rare. Here, we report a case of primary acinic cell carcinoma of the lung with prominent psammoma bodies. A 31-year-old man came to our hospital with a tumor in the basal segment of the lower lobe of the right lung. The tumor tissue displayed solid, acinar, or microcystic structures at different regions. A large amount of psammoma bodies were scattered in more than half of the tumor. The majority of the tumor cells were round or polygonal in shape, with abundant acidophilic granular or vacuolated cytoplasm...
January 19, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28214115/warm-summers-and-moderate-winter-precipitation-boost-rhododendron-ferrugineum-l-growth-in-the-taillefer-massif-french-alps
#3
L Francon, C Corona, E Roussel, J Lopez Saez, M Stoffel
Rhododendron ferrugineum L. is a widespread dwarf shrub species growing in high-elevation, alpine environments of the Western European Alps. For this reason, analysis of its growth rings offers unique opportunities to push current dendrochronological networks into extreme environments and way beyond the treeline. Given that different species of the same genus have been successfully used in tree-ring investigations, notably in the Himalayas where Rhododendron spp. has proven to be a reliable climate proxy, this study aims at (i) evaluating the dendroclimatological potential of R...
February 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28214067/nationwide-diabetes-related-lower-extremity-amputation-rates-in-secondary-care-treated-patients-with-diabetes-in-the-netherlands-dude-7
#4
Leonie Nijenhuis-Rosien, Steven Hans Hendriks, Nanne Kleefstra, Hendricus Jozef Gerardus Bilo, Gijs Wilhelmus Diederik Landman
AIMS: To estimate the annual amputation rate in all secondary care treated patients with diabetes in the Netherlands and specifically in patients known with diabetic retinopathy. METHODS: A nationwide population-based retrospective cohort study was performed including the years 2007-2011. Data of patients were retrieved from reimbursement registries for hospital care from a nationwide insurance database including codes for diabetes, retinopathy and amputation. Traumatic amputations were excluded...
February 2, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28213948/hourglass-shaped-right-ventricle-and-localized-constrictive-pericarditis
#5
Alper Karakus, Hasan Ari, Sencer Camci, Selma Ari, Ahmet Tutuncu, Mehmet Melek
Constrictive pericarditis is characterized by thick pericardial fibrosis and frequent calcification that progressively impairs diastolic filling of the heart. The diagnosis of constrictive pericarditis has been challenging even though multiple diagnostic modalities have been developed. The diagnosis of constructive pericarditis is especially difficult in localized constrictive pericarditis which is extremely rare. We report a case of localized constrictive pericarditis with a 3D multislice cardiac computed tomography (CT) finding of the constrictive band causing strangulation and hourglass shaping of the right ventricle...
February 18, 2017: Echocardiography
https://www.readbyqxmd.com/read/28213879/arthrogryposis-multiplex-congenita-classification-diagnosis-perioperative-care-and-anesthesia
#6
REVIEW
Lulu Ma, Xuerong Yu
Arthrogryposis multiplex congenita (AMC) is a rare disorder characterized by non-progressive, multiple contractures. In addition to affected extremities, patients may also present microstomia, decreased temporomandibular joint mobility. Although the etiology of AMC is unclear, any factor that decreases fetal movement is responsible for AMC. Thus, accurate diagnosis and classification are crucial to the appropriate treatment of AMC. The development of ultrasound technology has enabled prenatal diagnosis. Very early treatment is favorable, and multidisciplinary treatment is necessary to improve the function of AMC patients...
February 17, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28213825/pyrophosphate-hydrolysis-in-the-extremely-halophilic-archaeon-haloarcula-japonica-is-catalyzed-by-a-single-enzyme-with-a-broad-ionic-strength-range
#7
Satoshi Wakai, Akihiro Abe, Sotaro Fujii, Kaoru Nakasone, Yoshihiro Sambongi
The soluble protein fraction of the extremely halophilic archaeon Haloarcula japonica exhibits substantial inorganic pyrophosphate (PPi) hydrolysis activity in the presence of 2-4 M NaCl (Wakai et al, J Biol Chem 288:29247-29251, 2013), which provides high ionic strength (2-4). In this study, much higher PPi hydrolysis activity was unexpectedly detected, even with 0 M NaCl in the presence of 100-200 mM MgSO4, providing a much lower ionic strength of 0.4-0.8, in the same protein fraction. Na(+) and Mg(2+) ions were required for activity under high and low ionic strength conditions, respectively...
February 17, 2017: Extremophiles: Life Under Extreme Conditions
https://www.readbyqxmd.com/read/28213708/removal-mechanisms-for-extremely-high-level-fluoroquinolone-antibiotics-in-pharmaceutical-wastewater-treatment-plants
#8
Xinyan Guo, Zheng Yan, Yi Zhang, Xiangji Kong, Deyang Kong, Zhengjun Shan, Na Wang
Pharmaceutical wastewater treatment plants (PWWTPs) receive industrial effluents from the plant that contain extremely high levels of antibiotics and are regarded as one of the major sources of antibiotics in the environment. Two PWWTPs have been selected in Zhejiang Province, China, to assess the removal mechanisms of fluoroquinolone antibiotics (FQs). PWWTP A uses activated sludge with biocarriers in a moving bed biofilm reactor in anoxic and aerobic units, and PWWTP B uses biological units under anaerobic, aerobic, and anoxic conditions...
February 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28213670/emerging-genotype-phenotype-relationships-in-patients-with-large-nf1-deletions
#9
REVIEW
Hildegard Kehrer-Sawatzki, Victor-Felix Mautner, David N Cooper
The most frequent recurring mutations in neurofibromatosis type 1 (NF1) are large deletions encompassing the NF1 gene and its flanking regions (NF1 microdeletions). The majority of these deletions encompass 1.4-Mb and are associated with the loss of 14 protein-coding genes and four microRNA genes. Patients with germline type-1 NF1 microdeletions frequently exhibit dysmorphic facial features, overgrowth/tall-for-age stature, significant delay in cognitive development, large hands and feet, hyperflexibility of joints and muscular hypotonia...
February 17, 2017: Human Genetics
https://www.readbyqxmd.com/read/28213633/associations-between-pain-catastrophizing-and-cognitive-fusion-in-relation-to-pain-and-upper-extremity-function-among-hand-and-upper-extremity-surgery-patients
#10
Sezai Özkan, Emily L Zale, David Ring, Ana-Maria Vranceanu
BACKGROUND: Patients who present to hand surgery practices are at increased risk of psychological distress, pain, and disability. Greater catastrophic thinking about pain is associated with greater pain intensity, and initial evidence suggest that, together, catastrophic thinking about pain and cognitive fusion (i.e., interpretation of thoughts as true) are associated with poorer pain outcomes. PURPOSE: We tested whether cognitive fusion or catastrophic thinking interacts in relation to pain and upper extremity physical function among patients seeking care from a hand surgeon...
February 17, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/28213514/peripheral-membrane-interactions-boost-the-engagement-by-an-anti-hiv-1-broadly-neutralizing-antibody
#11
Edurne Rujas, José M M Caaveiro, Sara Insausti, Miguel García-Porras, Kouhei Tsumoto, José L Nieva
The 4E10 antibody displays an extreme breadth of HIV-1 neutralization and therefore constitutes a suitable model system for structure- guided vaccine design and immunotherapeutics against AIDS. In this regard, the relevance of auto- reactivity with membrane lipids for the biological function of this antibody is still a subject of controversy. To address this dispute, herein we have compared the membrane-partitioning ability of the 4E10 antibody and several of its variants, which were mutated at the region of the paratope surface in contact with the membrane-interface...
February 17, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28213471/attenuation-of-endoplasmic-reticulum-stress-by-caffeine-ameliorates-hyperoxia-induced-lung-injury
#12
Ru-Jeng Teng, Xigang Jing, Teresa Michalkiewicz, Adeleye J Afolayan, Tzong-Jin Wu, Girija G Konduri
Rodent pups exposed to hyperoxia develop lung changes similar to bronchopulmonary dysplasia (BPD) in extremely premature infants. Oxidative stress from hyperoxia can injure developing lungs through endoplasmic reticulum (ER) stress. Early caffeine treatment decreases the rate of BPD, but the mechanisms remain unclear. We hypothesized that caffeine attenuates hyperoxia-induced lung injury through its chemical chaperone property. Sprague-Dawley rat pups were raised either in 90% (hyperoxia) or 21% (normoxia) oxygen from postnatal day 1 (P1) to postnatal day 10 (P10) and then recovered in 21% oxygen until P21...
February 17, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28213317/developing-and-assessing-the-acceptability-of-an-epilepsy-first-aid-training-intervention-for-patients-who-visit-uk-emergency-departments-a-multi-method-study-of-patients-and-professionals
#13
Darlene A Snape, Myfanwy Morgan, Leone Ridsdale, Steve Goodacre, Anthony G Marson, Adam J Noble
Epilepsy affects around 1% of the UK population; 40% of whom experience two or more seizures annually. However, most Emergency Department (ED) visits by people with epilepsy (PWE) are clinically unnecessary. Evidence highlights that with correct training, seizures can be safely managed by patients and their families within the community. Arguably therefore, PWE who frequently visit the ED might benefit from a self-management intervention that improves their own and their families' confidence and ability in managing seizures...
February 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28213302/disrupting-effects-of-azocyclotin-to-the-hypothalamo-pituitary-gonadal-axis-and-reproduction-of-xenopus-laevis
#14
Shuying Li, Meng Li, Wenjun Gui, Qiangwei Wang, Guonian Zhu
Over the past few decades, the hazards associated with the extensive use of organictin compounds have become an issue of extreme concern, while at present the effects of these substances on amphibians remain poorly understood. In the present study, we chose azocyclotin, one of common use acaricides in China. We focused on sexual development and steroidogenesis disrupting effects of azocyclotin in the Xenopus laevis. Tadpoles were exposed to azocyclotin (0.05 and 0.5μg/L) for long-term (4 months) study. Results showed that exposure to azocyclotin caused developmental toxicity, including decreased survival, body weight, body length, gonadosomatic index, hepatosomatic index and female phenotype...
February 8, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28213258/p-aminothiophenol-coated-cdse-zns-quantum-dots-as-a-turn-on-fluorescent-probe-for-ph-detection-in-aqueous-media
#15
Dong Li, Hu Xu, Dan Li, Yuhong Wang
Since controlling hydrogen ion concentration (i.e. pH) is fairly important in various fields, developing a facile pH detection method is highly desired. Owing to the superior optical properties, semiconductor quantum dots (QDs) have been developed as a promising alternative for organic fluorophores in fluorescence analysis. In this study, a hydrophilic p-aminothiophenol (pATP) capped CdSe/ZnS QDs (denoted as pATP-QDs) as a selective "turn-on" fluorescence probe for pH in aqueous media is reported. The pATP-QDs probe easily obtained via ligand exchange are characterized by various analytic techniques including ultraviolet-visible, fourier transform infrared, fluorescence, time-resolved fluorescence spectroscopies, and transmission electron microscope etc...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213169/functional-outcomes-in-community-based-adults-with-borderline-personality-disorder
#16
Kristin N Javaras, Mary C Zanarini, James I Hudson, Shelly F Greenfield, John G Gunderson
Many individuals in clinical samples with borderline personality disorder (BPD) experience high levels of functional impairment. However, little is known about the levels of functional impairment experienced by individuals with BPD in the general community. To address this issue, we compared overall and domain-specific (educational/occupational; social; recreational) functioning in a sample of community-based individuals with BPD (n = 164); community-based individuals without BPD (n = 901); and clinically-ascertained individuals with BPD (n = 61)...
January 24, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28213145/how-are-you-feeling-a-personalized-methodology-for-predicting-mental-states-from-temporally-observable-physical-and-behavioral-information
#17
Suppawong Tuarob, Conrad S Tucker, Soundar Kumara, C Lee Giles, Aaron L Pincus, David E Conroy, Nilam Ram
It is believed that anomalous mental states such as stress and anxiety not only cause suffering for the individuals, but also lead to tragedies in some extreme cases. The ability to predict the mental state of an individual at both current and future time periods could prove critical to healthcare practitioners. Currently, the practical way to predict an individual's mental state is through mental examinations that involve psychological experts performing the evaluations. However, such methods can be time and resource consuming, mitigating their broad applicability to a wide population...
February 14, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28213101/additively-manufactured-metallic-porous-biomaterials-based-on-minimal-surfaces-a-unique-combination-of-topological-mechanical-and-mass-transport-properties
#18
F S L Bobbert, K Lietaert, A A Eftekhari, B Pouran, S M Ahmadi, H Weinans, A A Zadpoor
: Porous biomaterials that simultaneously mimic the topological, mechanical, and mass transport properties of bone are in great demand but are rarely found in the literature. In this study, we rationally designed and additively manufactured (AM) porous metallic biomaterials based on four different types of triply periodic minimal surfaces (TPMS) that mimic the properties of bone to an unprecedented level of multi-physics detail. Sixteen different types of porous biomaterials were rationally designed and fabricated using selective laser melting (SLM) from a titanium alloy (Ti-6Al-4V)...
February 14, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28213066/inguinal-lymph-node-presenting-as-the-delayed-site-of-metastasis-in-early-stage-endometrial-carcinoma-case-report
#19
Shomaila Amir M Akbar, Mutahir A Tunio, Wafa AlShakweer, AbdulAziz AlObaid, Mushabbab AlAsiri
INTRODUCTION: Inguinal lymph nodes are the frequent sites of metastasis for malignant lymphoma, squamous cell carcinoma of anal canal, vulva and penis, malignant melanoma and squamous cell carcinoma of skin over lower extremities or trunk. Anatomically, endometrial carcinoma is less likely to spread to the superficial or deep inguinal lymph nodes, thus metastatic involvement of these lymph nodes can easily be overlooked. CASE PRESENTATION: Here-in we report a case of a 65-year old Saudi morbid obese female, who presented with left inguinal lymphadenopathy as initial delayed site of metastasis almost 19 months after the initial treatment for FIGO IA endometrial carcinoma...
January 19, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28213048/low-field-single-sided-nmr-for-one-shot-1d-mapping-application-to-membranes
#20
Patrick Judeinstein, Filippo Ferdeghini, Rodrigo Oliveira-Silva, Jean-Marc Zanotti, Dimitrios Sakellariou
Many single-sided permanent magnet NMR systems have been proposed over the years allowing for 1D proton-density profiling, diffusion measurements and relaxometry. In this manuscript we make use of a recently published unilateral magnet for low-field NMR exhibiting an extremely uniform magnetic field gradient with moderate strength and cylindrical symmetry, allowing for a well-defined sweet spot. Combined with a goniometer, our system is used to characterize precisely the uniformity of its gradient and to achieve micrometric precision 1D profiling, as well as spatially localized relaxometry and diffusometry on thick (∼150μm) membrane samples...
February 8, 2017: Journal of Magnetic Resonance
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