keyword
MENU ▼
Read by QxMD icon Read
search

Deep Web

keyword
https://www.readbyqxmd.com/read/29154402/transvaginal-ultrasound-tvs-versus-magnetic-resonance-mr-for-diagnosing-deep-infiltrating-endometriosis-a-systematic-review-and-meta-analysis
#1
REVIEW
S Guerriero, L Saba, M A Pascual, S Ajossa, I Rodriguez, V Mais, J L Alcazar
OBJECTIVES: To perform a systematic review of studies comparing the diagnostic accuracy of TVS and MRI in Deep Infiltrating Endometriosis (DIE) including only studies in which patients have been underwent both techniques. METHODS: An extensive search of papers comparing TVS and MRI in DIE was performed in Medline (Pubmed) and Web of Sciences from January 1989 to January 2016. Studies were considered eligible if they reported on the use of TVS and MRI in the same set of patients for the preoperative detection of endometriosis in pelvic locations in women with clinical suspicion of DIE using the surgical data as a reference standard...
November 20, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29092932/a-galaxy-implementation-of-next-generation-clustered-heatmaps-for-interactive-exploration-of-molecular-profiling-data
#2
Bradley M Broom, Michael C Ryan, Robert E Brown, Futa Ikeda, Mark Stucky, David W Kane, James Melott, Chris Wakefield, Tod D Casasent, Rehan Akbani, John N Weinstein
Clustered heatmaps are the most frequently used graphics for visualization of molecular profiling data in biology. However, they are generally rendered as static, or only modestly interactive, images. We have now used recent advances in web technologies to produce interactive "next-generation" clustered heatmaps (NG-CHM) that enable extreme zooming and navigation without loss of resolution. NG-CHMs also provide link-outs to additional information sources and include other features that facilitate deep exploration of the biology behind the image...
November 1, 2017: Cancer Research
https://www.readbyqxmd.com/read/29062037/abrupt-stop-of-deep-water-turnover-with-lake-warming-drastic-consequences-for-algal-primary-producers
#3
Yana Yankova, Stefan Neuenschwander, Oliver Köster, Thomas Posch
After strong fertilization in the 20(th) century, many deep lakes in Central Europe are again nutrient poor due to long-lasting restoration (re-oligotrophication). In line with reduced phosphorus and nitrogen loadings, total organismic productivity decreased and lakes have now historically low nutrient and biomass concentrations. This caused speculations that restoration was overdone and intended fertilizations are needed to ensure ecological functionality. Here we show that recent re-oligotrophication processes indeed accelerated, however caused by lake warming...
October 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29056853/evaluation-of-risk-minimization-activities-for-cyproterone-acetate-2%C3%A2-mg-ethinylestradiol-35%C3%A2-%C3%A2%C2%B5g-a-cross-sectional-physician-survey
#4
Kimberly H Davis, Alex Asiimwe, Laurie J Zografos, David J McSorley, Elizabeth B Andrews
BACKGROUND: Cyproterone acetate 2 mg/ethinylestradiol 35 µg, an estrogen/progestogen treatment with anti-androgenic properties, shares a thromboembolism risk with combined hormonal contraceptives. Educational materials (i.e., direct healthcare professional communication, patient information card, prescriber checklist) were distributed to physicians to increase risk awareness. OBJECTIVE: The objective of this study was to measure physician knowledge of thromboembolism risk of cyproterone acetate 2 mg/ethinylestradiol 35 µg and ascertain whether physicians received the educational materials...
2017: Pharmaceutical Medicine
https://www.readbyqxmd.com/read/29050094/-relationship-between-work-%C3%A2-type-of-congenital-first-branchial-cleft-anomaly-and-facial-nerve-and-surgical-strategies
#5
B Zhang, L S Chen, S L Huang, L Liang, X X Gong, P N Wu, S Y Zhang, X N Luo, J D Zhan, X L Sheng, Z M Lu
Objective: To investigate the relationship between Work Ⅱ type of congenital first branchial cleft anomaly (CFBCA) and facial nerve and discuss surgical strategies. Methods: Retrospective analysis of 37 patients with CFBCA who were treated from May 2005 to September 2016. Among 37 cases with CFBCA, 12 males and 25 females; 24 in the left and 13 in the right; the age at diagnosis was from 1 to 76 ( years, with a median age of 20, 24 cases with age of 18 years or less and 13 with age more than 18 years; duration of disease ranged from 1 to 10 years (median of 6 years); 4 cases were recurren after fistula resection...
October 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29049195/the-efficacy-of-combined-intra-articular-and-intravenous-tranexamic-acid-for-blood-loss-in-primary-total-knee-arthroplasty-a-meta-analysis
#6
REVIEW
Zhao Wang, Xiaofei Shen
BACKGROUND: This meta-analysis aimed to illustrate the efficacy and safety of combined topical and intravenous (IV) tranexamic acid (TXA) for blood loss control in primary total knee arthroplasty (TKA) patients. METHODS: In April 2017, a systematic computer-based search was conducted in PubMed, EMBASE, Web of Science, Cochrane Database of Systematic Reviews, and Google database. Data on patients prepared for TKA surgery in studies that compared combined topical and IV TXA versus placebo, topical, or IV TXA alone were retrieved...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049073/postoperative-outcomes-in-obstructive-sleep-apnea-patients-undergoing-cardiac-surgery-a-systematic-review-and-meta-analysis-of-comparative-studies
#7
Mahesh Nagappa, George Ho, Jayadeep Patra, Jean Wong, Mandeep Singh, Roop Kaw, Davy Cheng, Frances Chung
BACKGROUND: Obstructive sleep apnea (OSA) is a common comorbidity in patients undergoing cardiac surgery and may predispose patients to postoperative complications. The purpose of this meta-analysis is to determine the evidence of postoperative complications associated with OSA patients undergoing cardiac surgery. METHODS: A literature search of Cochrane Database of Systematic Reviews, Medline, Medline In-process, Web of Science, Scopus, EMBASE, Cochrane Central Register of Controlled Trials, and CINAHL until October 2016 was performed...
October 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29036616/deeploc-prediction-of-protein-subcellular-localization-using-deep-learning
#8
José Juan Almagro Armenteros, Casper Kaae Sønderby, Søren Kaae Sønderby, Henrik Nielsen, Ole Winther
Motivation: The prediction of eukaryotic protein subcellular localization is a well-studied topic in bioinformatics due to its relevance in proteomics research. Many machine learning methods have been successfully applied in this task, but in most of them, predictions rely on annotation of homologues from knowledge databases. For novel proteins where no annotated homologues exist, and for predicting the effects of sequence variants, it is desirable to have methods for predicting protein properties from sequence information only...
November 1, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29036529/itsonedb-a-comprehensive-collection-of-eukaryotic-ribosomal-rna-internal-transcribed-spacer-1-its1-sequences
#9
Monica Santamaria, Bruno Fosso, Flavio Licciulli, Bachir Balech, Ilaria Larini, Giorgio Grillo, Giorgio De Caro, Sabino Liuni, Graziano Pesole
A holistic understanding of environmental communities is the new challenge of metagenomics. Accordingly, the amplicon-based or metabarcoding approach, largely applied to investigate bacterial microbiomes, is moving to the eukaryotic world too. Indeed, the analysis of metabarcoding data may provide a comprehensive assessment of both bacterial and eukaryotic composition in a variety of environments, including human body. In this respect, whereas hypervariable regions of the 16S rRNA are the de facto standard barcode for bacteria, the Internal Transcribed Spacer 1 (ITS1) of ribosomal RNA gene cluster has shown a high potential in discriminating eukaryotes at deep taxonomic levels...
September 25, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29028931/deepgo-predicting-protein-functions-from-sequence-and-interactions-using-a-deep-ontology-aware-classifier
#10
Maxat Kulmanov, Mohammed Asif Khan, Robert Hoehndorf
Motivation: A large number of protein sequences are becoming available through the application of novel high-throughput sequencing technologies. Experimental functional characterization of these proteins is time-consuming and expensive, and is often only done rigorously for few selected model organisms. Computational function prediction approaches have been suggested to fill this gap. The functions of proteins are classified using the Gene Ontology (GO), which contains over 40,000 classes...
September 28, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29027404/transvaginal-ultrasound-versus-magnetic-resonance-imaging-for-preoperative-assessment-of-myometrial-infiltration-in-patients-with-endometrial-cancer-a-systematic-review-and-meta-analysis
#11
Juan Luis Alcázar, Begoña Gastón, Beatriz Navarro, Rocío Salas, Juana Aranda, Stefano Guerriero
OBJECTIVE: To compare the diagnostic accuracy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for detecting myometrial infiltration (MI) in endometrial carcinoma. METHODS: An extensive search of papers comparing TVS and MRI in assessing MI in endometrial cancer was performed in MEDLINE (PubMed), Web of Science, and Cochrane Database from January 1989 to January 2017. Quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/28989035/ploc-mgneg-predict-subcellular-localization-of-gram-negative-bacterial-proteins-by-deep-gene-ontology-learning-via-general-pseaac
#12
Xiang Cheng, Xuan Xiao, Kuo-Chen Chou
Information of the proteins' subcellular localization is crucially important for revealing their biological functions in a cell, the basic unit of life. With the avalanche of protein sequences generated in the postgenomic age, it is highly desired to develop computational tools for timely identifying their subcellular locations based on the sequence information alone. The current study is focused on the Gram-negative bacterial proteins. Although considerable efforts have been made in protein subcellular prediction, the problem is far from being solved yet...
October 6, 2017: Genomics
https://www.readbyqxmd.com/read/28968389/estimating-time-of-hiv-1-infection-from-next-generation-sequence-diversity
#13
Vadim Puller, Richard Neher, Jan Albert
Estimating the time since infection (TI) in newly diagnosed HIV-1 patients is challenging, but important to understand the epidemiology of the infection. Here we explore the utility of virus diversity estimated by next-generation sequencing (NGS) as novel biomarker by using a recent genome-wide longitudinal dataset obtained from 11 untreated HIV-1-infected patients with known dates of infection. The results were validated on a second dataset from 31 patients. Virus diversity increased linearly with time, particularly at 3rd codon positions, with little inter-patient variation...
October 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28966051/deep-brain-stimulation-for-disorders-of-consciousness-systematic-review-of-cases-and-ethics
#14
REVIEW
Jonathan Vanhoecke, Marwan Hariz
BACKGROUND: A treatment for patients suffering from prolonged severely altered consciousness is not available. The success of Deep Brain Stimulation (DBS) in diseases such as Parkinson's, dystonia and essential tremor provided a renewed impetus for its application in Disorders of Consciousness (DoC). OBJECTIVE: To evaluate the rationale for DBS in patients with DoC, through systematic review of literature containing clinical data and ethical considerations. METHODS: Articles from PubMed, Embase, Medline and Web of Science were systematically reviewed...
August 24, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28961795/improving-protein-fold-recognition-by-extracting-fold-specific-features-from-predicted-residue-residue-contacts
#15
Jianwei Zhu, Haicang Zhang, Shuai Cheng Li, Chao Wang, Lupeng Kong, Shiwei Sun, Wei-Mou Zheng, Dongbo Bu
Motivation: Accurate recognition of protein fold types is a key step for template-based prediction of protein structures. The existing approaches to fold recognition mainly exploit the features derived from alignments of query protein against templates. These approaches have been shown to be successful for fold recognition at family level, but usually failed at superfamily/fold levels. To overcome this limitation, one of the key points is to explore more structurally-informative features of proteins...
August 16, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28951288/on-or-off-pump-coronary-artery-bypass-grafting-for-octogenarians-a%C3%A2-meta-analysis-of-comparative-studies-involving-27-623-patients
#16
REVIEW
Habib Khan, Mohsin Uzzaman, Umberto Benedetto, Salman Butt, Shahzad G Raja
OBJECTIVE: Coronary artery bypass grafting (CABG) is being increasingly offered to octogenarians. Both on- and off-pump CABG are reported as effective surgical revascularization strategies for octogenarians by single institution studies. However, the issue of superiority of one strategy over the other for octogenarians remains unresolved due to limited sample size of these studies. A meta-analysis of studies comparing outcomes of on- and off-pump CABG in octogenarians was undertaken to address the issue...
November 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28942919/organism-level-analysis-of-vaccination-reveals-networks-of-protection-across-tissues
#17
Motohiko Kadoki, Ashwini Patil, Cornelius C Thaiss, Donald J Brooks, Surya Pandey, Deeksha Deep, David Alvarez, Ulrich H von Andrian, Amy J Wagers, Kenta Nakai, Tarjei S Mikkelsen, Magali Soumillon, Nicolas Chevrier
A fundamental challenge in immunology is to decipher the principles governing immune responses at the whole-organism scale. Here, using a comparative infection model, we observe immune signal propagation within and between organs to obtain a dynamic map of immune processes at the organism level. We uncover two inter-organ mechanisms of protective immunity mediated by soluble and cellular factors. First, analyzing ligand-receptor connectivity across tissues reveals that type I IFNs trigger a whole-body antiviral state, protecting the host within hours after skin vaccination...
October 5, 2017: Cell
https://www.readbyqxmd.com/read/28934644/cyriax-s-deep-friction-massage-application-parameters-evidence-from-a-cross-sectional-study-with-physiotherapists
#18
Paula Chaves, Daniela Simões, Maria Paço, Francisco Pinho, José Alberto Duarte, Fernando Ribeiro
BACKGROUND: Deep friction massage is one of several physiotherapy interventions suggested for the management of tendinopathy. OBJECTIVES: To determine the prevalence of deep friction massage use in clinical practice, to characterize the application parameters used by physiotherapists, and to identify empirical model-based patterns of deep friction massage application in degenerative tendinopathy. DESIGN: observational, analytical, cross-sectional and national web-based survey...
September 14, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28931949/hydrothermal-activity-functional-diversity-and-chemoautotrophy-are-major-drivers-of-seafloor-carbon-cycling
#19
James B Bell, Clare Woulds, Dick van Oevelen
Hydrothermal vents are highly dynamic ecosystems and are unusually energy rich in the deep-sea. In situ hydrothermal-based productivity combined with sinking photosynthetic organic matter in a soft-sediment setting creates geochemically diverse environments, which remain poorly studied. Here, we use comprehensive set of new and existing field observations to develop a quantitative ecosystem model of a deep-sea chemosynthetic ecosystem from the most southerly hydrothermal vent system known. We find evidence of chemosynthetic production supplementing the metazoan food web both at vent sites and elsewhere in the Bransfield Strait...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28910502/using-narrative-inquiry-to-listen-to-the-voices-of-adolescent-mothers-in-relation-to-their-use-of-social-networking-sites-sns
#20
Samantha Nolan, Joyce Hendricks, Moira Williamson, Sally Ferguson
AIM: This article presents a discussion highlighting the relevance and strengths of using narrative inquiry to explore experiences of social networking site (SNS) use by adolescent mothers. BACKGROUND: Narrative inquiry as a method reveals truths about holistic human experience. Knowledge gleaned from personal narratives informs nursing knowledge and clinical practice. This approach gives voice to adolescent mothers in relation to their experiences with SNS as a means of providing social support...
September 14, 2017: Journal of Advanced Nursing
keyword
keyword
73742
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"