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https://www.readbyqxmd.com/read/28317324/big-in-the-benthos-future-change-of-seafloor-community-biomass-in-a-global-body-size-resolved-model
#1
Andrew Yool, Adrian P Martin, Thomas R Anderson, Brian J Bett, Daniel O B Jones, Henry A Ruhl
Deep-water benthic communities in the ocean are almost wholly dependent on near-surface pelagic ecosystems for their supply of energy and material resources. Primary production in sunlit surface waters is channelled through complex food webs that extensively recycle organic material, but lose a fraction as particulate organic carbon (POC) that sinks into the ocean interior. This exported production is further rarefied by microbial breakdown in the abyssal ocean, but a residual ultimately drives diverse assemblages of seafloor heterotrophs...
March 19, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28303119/viruses-and-protists-induced-mortality-of-prokaryotes-around-the-antarctic-peninsula-during-the-austral-summer
#2
Dolors Vaqué, Julia A Boras, Francesc Torrent-Llagostera, Susana Agustí, Jesús M Arrieta, Elena Lara, Yaiza M Castillo, Carlos M Duarte, Maria M Sala
During the Austral summer 2009 we studied three areas surrounding the Antarctic Peninsula: the Bellingshausen Sea, the Bransfield Strait and the Weddell Sea. We aimed to investigate, whether viruses or protists were the main agents inducing prokaryotic mortality rates, and the sensitivity to temperature of prokaryotic heterotrophic production and mortality based on the activation energy (Ea) for each process. Seawater samples were taken at seven depths (0.1-100 m) to quantify viruses, prokaryotes and protists abundances, and heterotrophic prokaryotic production (PHP)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28290556/porewater-methane-transport-within-the-gas-vesicles-of-diurnally-migrating-chaoborus-spp-an-energetic-advantage
#3
Daniel F McGinnis, Sabine Flury, Kam W Tang, Hans-Peter Grossart
Diurnally-migrating Chaoborus spp. reach populations of up to 130,000 individuals m(-2) in lakes up to 70 meters deep on all continents except Antarctica. Linked to eutrophication, migrating Chaoborus spp. dwell in the anoxic sediment during daytime and feed in the oxic surface layer at night. Our experiments show that by burrowing into the sediment, Chaoborus spp. utilize the high dissolved gas partial pressure of sediment methane to inflate their tracheal sacs. This mechanism provides a significant energetic advantage that allows the larvae to migrate via passive buoyancy rather than more energy-costly swimming...
March 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28288878/outcomes-and-complications-of-percutaneous-versus-open-repair-of-acute-achilles-tendon-rupture-a-meta-analysis
#4
REVIEW
Bo Yang, Yang Liu, Shunli Kan, Di Zhang, Hong Xu, Feifei Liu, Guangzhi Ning, Shiqing Feng
BACKGROUND: Acute Achilles tendon rupture (AATR) is a frequent injury occurring dominantly in young to middle-aged males. Outcomes and complications between percutaneous and open repair are still controversial. Thus, the purpose of this meta-analysis is to evaluate the outcomes and complications of these two operative methods. MATERIALS AND METHODS: We searched multiple databases: PubMed, Web of Science, EMBASE and the Cochrane Library up to October 2016. Two reviewers independently screened the studies for eligibility, evaluated the quality and extracted data from eligible studies, with confirmation by cross-checking...
March 11, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28281832/outcomes-of-introducing-early-learners-to-interprofessional-competencies-in-a-classroom-setting
#5
Kelly S Lockeman, Sharon K Lanning, Alan W Dow, Joseph A Zorek, Deborah DiazGranados, Carole K Ivey, Shawne Soper
PROBLEM: Although interprofessional practice is important for improving healthcare delivery, there is little evidence describing interprofessional education (IPE) outcomes beyond changes in attitudes and knowledge of prelicensure learners. More rigorous evaluation of early IPE is needed to determine its impact on teaching interprofessional collaborative practice and providing a solid foundation for applying collaborative skills in the clinical environment. INTERVENTION: First-year students (N = 679) in 7 health professions programs participated in a 4-session series focusing on professional roles and responsibilities, teams and teamwork, and the healthcare system...
March 10, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28269272/a-pdms-based-optical-waveguide-for-transcutaneous-powering-of-microelectrode-arrays
#6
Ali Ersen, Mesut Sahin
Implantable microelectrode arrays (MEAs) usually have on-site electronics that need to be powered, both in neural recording and stimulation applications. Interconnecting wires between implanted electrodes and the outside world constitute a major source of complications. Our solution to this tethering problem is to design a light waveguide that can collect the optical power transcutaneously and transmit it to the microelectrode array where it is to be converted to an electric current. A polydimethylsiloxane (PDMS)-based waveguide was fabricated and its attenuation was measured in vitro and found to be 0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28236811/neuropsychological-performance-changes-following-subthalamic-versus-pallidal-deep-brain-stimulation-in-parkinson-s-disease-a-systematic-review-and-metaanalysis
#7
Ahmed Elgebaly, Mohamed Elfil, Attia Attia, Mayar Magdy, Ahmed Negida
BACKGROUND: Studies comparing subthalamus (STN) and globus pallidus internus (GPi) deep brain stimulation (DBS) for the management of Parkinson's disease in terms of neuropsychological performance are scarce and heterogeneous. Therefore, we performed a systematic review and metaanalysis to compare neuropsychological outcomes following STN DBS versus GPi DBS. METHODS: A computer literature search of PubMed, the Web of Science, and Cochrane Central was conducted. Records were screened for eligible studies, and data were extracted and synthesized using Review Manager (v...
February 27, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28227506/a-pdms-based-optical-waveguide-for-transcutaneous-powering-of-microelectrode-arrays
#8
Ali Ersen, Mesut Sahin, Ali Ersen, Mesut Sahin, Ali Ersen, Mesut Sahin
Implantable microelectrode arrays (MEAs) usually have on-site electronics that need to be powered, both in neural recording and stimulation applications. Interconnecting wires between implanted electrodes and the outside world constitute a major source of complications. Our solution to this tethering problem is to design a light waveguide that can collect the optical power transcutaneously and transmit it to the microelectrode array where it is to be converted to an electric current. A polydimethylsiloxane (PDMS)-based waveguide was fabricated and its attenuation was measured in vitro and found to be 0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222709/combined-application-versus-topical-and-intravenous-application-of-tranexamic-acid-following-primary-total-hip-arthroplasty-a-meta-analysis
#9
Pei Zhang, Yuan Liang, Pengtao Chen, Yongchao Fang, Jinshan He, Jingcheng Wang
BACKGROUND: The use of intravenous (IV) or topical tranexamic acid (TXA) in total hip arthroplasty has been proven to be effective and safe in total hip arthroplasty. However, which of these two administration routes is better has not been determined. The combined administration of TXA has been used in total knee arthroplasty with satisfactory results. We hypothesized that combined application of TXA may be the most effective way without increased rate of thrombotic events such as deep vein thrombosis (DVT) and pulmonary embolisms (PE) in patients subjected to primary total hip replacement (THA)...
February 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28182578/review-of-heavy-metal-accumulation-on-aquatic-environment-in-northern-east-mediterrenean-sea-part-i-some-essential-metals
#10
Ayşe Bahar Yılmaz, Alper Yanar, Ela Nur Alkan
All pollutants can reach the aquatic environments and the levels of heavy metals in upper members of the food web like fish can reach values many times higher than those found in aquatic environment or in sediments. Although heavy metals are essential or non-essential, all heavy metals are potentially harmful to humans and most organisms at some level of exposure and absorption. Marine organisms are good indicators for long-term monitoring of metal accumulation. The present review study is for evaluation of the data from previous studies about the toxic effects of selected heavy metals, like essential metals (copper, zinc, iron, chromium, and manganese), on seawater, sediment, and in different tissues of aquatic animals (demersal and bentic fish, invertabres) collected from different areas in Northern East Mediterrenean Sea since the 1990s...
March 1, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28176374/assessment-of-anatomical-knowledge-approaches-taken-by-higher-education-institutions
#11
REVIEW
Bipasha Choudhury, Anthony Freemont
Assessment serves the primary function of determining a student's competence in a subject. Several different assessment formats are available for assessing anatomical skills, knowledge and understanding and, as assessment can drive learning, a careful selection of assessments can help to engender the correct deep learning facility required of the safe clinical practitioner. The aim of this review was to survey the published literature to see whether higher education institutions are taking an andragogical approach to assessment...
April 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28170080/mesh-fixation-with-glue-versus-suture-for-chronic-pain-and-recurrence-in-lichtenstein-inguinal-hernioplasty
#12
REVIEW
Ping Sun, Xiang Cheng, Shichang Deng, Qinggang Hu, Yi Sun, Qichang Zheng
BACKGROUND: Chronic pain following mesh-based inguinal hernia repair is frequently reported, and has a significant impact on quality of life. Whether mesh fixation with glue can reduce chronic pain without increasing the recurrence rate is still controversial. OBJECTIVES: To determine whether tissue adhesives can reduce postoperative complications, especially chronic pain, with no increase in recurrence rate, compared with sutures for mesh fixation in Lichtenstein hernia repair...
February 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28158264/recognition-of-prokaryotic-and-eukaryotic-promoters-using-convolutional-deep-learning-neural-networks
#13
Ramzan Kh Umarov, Victor V Solovyev
Accurate computational identification of promoters remains a challenge as these key DNA regulatory regions have variable structures composed of functional motifs that provide gene-specific initiation of transcription. In this paper we utilize Convolutional Neural Networks (CNN) to analyze sequence characteristics of prokaryotic and eukaryotic promoters and build their predictive models. We trained a similar CNN architecture on promoters of five distant organisms: human, mouse, plant (Arabidopsis), and two bacteria (Escherichia coli and Bacillus subtilis)...
2017: PloS One
https://www.readbyqxmd.com/read/28155665/tea-the-epigenome-platform-for-arabidopsis-methylome-study
#14
Sheng-Yao Su, Shu-Hwa Chen, I-Hsuan Lu, Yih-Shien Chiang, Yu-Bin Wang, Pao-Yang Chen, Chung-Yen Lin
BACKGROUND: Bisulfite sequencing (BS-seq) has become a standard technology to profile genome-wide DNA methylation at single-base resolution. It allows researchers to conduct genome-wise cytosine methylation analyses on issues about genomic imprinting, transcriptional regulation, cellular development and differentiation. One single data from a BS-Seq experiment is resolved into many features according to the sequence contexts, making methylome data analysis and data visualization a complex task...
December 22, 2016: BMC Genomics
https://www.readbyqxmd.com/read/28152994/transductive-learning-as-an-alternative-to-translation-initiation-site-identification
#15
Cristiano Lacerda Nunes Pinto, Cristiane Neri Nobre, Luis Enrique Zárate
BACKGROUND: The correct protein coding region identification is an important and latent problem in the molecular biology field. This problem becomes a challenge due to the lack of deep knowledge about the biological systems and unfamiliarity of conservative characteristics in the messenger RNA (mRNA). Therefore, it is fundamental to research for computational methods aiming to help the patterns discovery for identification of the Translation Initiation Sites (TIS). In the field of Bioinformatics, machine learning methods have been widely applied based on the inductive inference, as Inductive Support Vector Machine (ISVM)...
February 2, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28141874/metabox-a-toolbox-for-metabolomic-data-analysis-interpretation-and-integrative-exploration
#16
Kwanjeera Wanichthanarak, Sili Fan, Dmitry Grapov, Dinesh Kumar Barupal, Oliver Fiehn
Similar to genomic and proteomic platforms, metabolomic data acquisition and analysis is becoming a routine approach for investigating biological systems. However, computational approaches for metabolomic data analysis and integration are still maturing. Metabox is a bioinformatics toolbox for deep phenotyping analytics that combines data processing, statistical analysis, functional analysis and integrative exploration of metabolomic data within proteomic and transcriptomic contexts. With the number of options provided in each analysis module, it also supports data analysis of other 'omic' families...
2017: PloS One
https://www.readbyqxmd.com/read/28127828/psychiatric-symptomatology-after-delirium-a-systematic-review
#17
REVIEW
Clare Langan, Deep P Sarode, Tom C Russ, Susan D Shenkin, Alan Carson, Alasdair M J Maclullich
Delirium is an acute and usually transient severe neuropsychiatric syndrome associated with significant long-term physical morbidity. However, its chronic psychiatric sequelae remain poorly characterized. To investigate the prevalence of psychiatric symptoms, namely anxiety, depressive, and post-traumatic stress disorder (PTSD) symptoms after delirium, a systematic literature search of MEDLINE, EMBASE and PsycINFO databases was performed independently by two authors in March 2016. Bibliographies were hand-searched, and a forward- and backward-citation search using Web of Science was performed for all included studies...
January 27, 2017: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/28124434/speech-and-language-adverse-effects-after-thalamotomy-and-deep-brain-stimulation-in-patients-with-movement-disorders-a-meta-analysis
#18
REVIEW
Soha Alomar, Nicolas K K King, Joseph Tam, Ausaf A Bari, Clement Hamani, Andres M Lozano
BACKGROUND: The thalamus has been a surgical target for the treatment of various movement disorders. Commonly used therapeutic modalities include ablative and nonablative procedures. A major clinical side effect of thalamic surgery is the appearance of speech problems. OBJECTIVE: This review summarizes the data on the development of speech problems after thalamic surgery. METHODS: A systematic review and meta-analysis was performed using nine databases, including Medline, Web of Science, and Cochrane Library...
January 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28114927/local-anesthetic-infusion-pump-for-pain-management-following-total-knee-arthroplasty-a-meta-analysis
#19
Yeying Zhang, Ming Lu, Cheng Chang
BACKGROUND: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) were to evaluate the effect and safety of local anesthetic infusion pump versus placebo for pain management following total knee arthroplasty (TKA). METHODS: In September 2016, a systematic computer-based search was conducted in the Pubmed, ISI Web of Knowledge, Embase, Cochrane Database of Systematic Reviews. Randomized controlled trials of patients prepared for primary TKA that compared local anesthetic infusion pump versus placebo for pain management following TKA were retrieved...
January 23, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28113887/aggnet-deep-learning-from-crowds-for-mitosis-detection-in-breast-cancer-histology-images
#20
Shadi Albarqouni, Christoph Baur, Felix Achilles, Vasileios Belagiannis, Stefanie Demirci, Nassir Navab
The lack of publicly available ground-truth data has been identified as the major challenge for transferring recent developments in deep learning to the biomedical imaging domain. Though crowdsourcing has enabled annotation of large scale databases for real world images, its application for biomedical purposes requires a deeper understanding and hence, more precise definition of the actual annotation task. The fact that expert tasks are being outsourced to non-expert users may lead to noisy annotations introducing disagreement between users...
February 11, 2016: IEEE Transactions on Medical Imaging
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