keyword
MENU ▼
Read by QxMD icon Read
search

Behavioral Addiction

keyword
https://www.readbyqxmd.com/read/28531770/treatment-consumption-and-treatment-re-enrollment-in-ghb-dependent-patients-in-the-netherlands
#1
Martijn S van Noorden, Ton Mol, Jeroen Wisselink, Wil Kuijpers, Boukje A G Dijkstra
BACKGROUND: The objective of this study was to assess treatment consumption and re-enrollment in treatment in patients with gamma-hydroxybutyrate (GHB)-dependence in Dutch Addiction Treatment Centers (ATCs) in comparison with other addictions. METHODS: A cohort-study using nationwide administrative data from regular Dutch ATCs associated with the Dutch National Alcohol and Drugs Information System (LADIS), covering an estimated 95% of ATCs. We selected in- and out-patients with alcohol, drug and/or behavioral addictions with a first treatment episode in 2008-2011 and consecutive treatments until 2013 (n=71,679)...
May 16, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28531297/mechanisms-of-kappa-opioid-receptor-potentiation-of-dopamine-d2-receptor-function-in-quinpirole-induced-locomotor-sensitization-in-rats
#2
Angélica P Escobar, Marcela P González, Rodrigo C Meza, Verónica Noches, Pablo Henny, Katia Gysling, Rodrigo A España, José A Fuentealba, María E Andrés
Background: Increased locomotor activity in response to the same stimulus is an index of behavioral sensitization observed in preclinical models of drug addiction and compulsive behaviors. Repeated administration of Quinpirole (QNP), a D2/D3 dopamine agonist, induces locomotor sensitization. This effect is potentiated and accelerated by co-administration of U69593, a kappa opioid receptor agonist (KOR). The mechanism underlying KOR potentiation of QNP-induced locomotor sensitization remains to be elucidated...
May 22, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28531265/utility-of-nonhuman-primates-in-substance-use-disorders-research
#3
Matthew L Banks, Paul W Czoty, Sidney S Negus
Substance use disorders (i.e., drug addiction) constitute a global and insidious public health issue. Preclinical biomedical research has been invaluable in elucidating the environmental, biological, and pharmacological determinants of drug abuse and in the process of developing innovative pharmacological and behavioral treatment strategies. For more than 70 years, nonhuman primates have been utilized as research subjects in biomedical research related to drug addiction. There are already several excellent published reviews highlighting species differences in both pharmacodynamics and pharmacokinetics between rodents and nonhuman primates in preclinical substance abuse research...
May 20, 2017: ILAR Journal
https://www.readbyqxmd.com/read/28529494/sensation-seeking-and-online-gaming-addiction-in-adolescents-a-moderated-mediation-model-of-positive-affective-associations-and-impulsivity
#4
Jianping Hu, Shuangju Zhen, Chengfu Yu, Qiuyan Zhang, Wei Zhang
Based on the Dual Systems Model (Somerville et al., 2010; Steinberg, 2010a) and the biosocial-affect model (Romer and Hennessy, 2007) of adolescent sensation seeking and problem behaviors, the present study examined how (affective associations with online games as a mediator) and when (impulsivity as a moderator) did sensation seeking influence online gaming addiction in adolescence. A total of 375 Chinese male adolescents (mean age = 16.02 years, SD = 0.85) from southern China completed anonymous questionnaires regarding sensation seeking, positive affective associations with online games, impulsivity, and online gaming addiction...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28528203/changes-in-resting-state-functional-brain-connectivity-and-withdrawal-symptoms-are-associated-with-acute-electronic-cigarette-use
#5
Andréa L Hobkirk, Travis T Nichols, Jonathan Foulds, Jessica M Yingst, Susan Veldheer, Shari Hrabovsky, John Richie, Thomas Eissenberg, Stephen J Wilson
Resting state functional brain connectivity (rsFC) may be an important neuromarker of smoking behavior. Prior research has shown, among cigarette smokers, that nicotine administration alters rsFC within frontal and parietal cortices involved in executive control, as well as striatal regions that drive reward processing. These changes in rsFC have been associated with reductions in withdrawal symptom severity. We currently have a limited understanding of how rsFC is affected by the use of electronic cigarettes (ecigs), an increasingly popular class of products, the members of which deliver nicotine with varying effectiveness...
May 17, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28527717/inhibition-of-the-lateral-habenular-camk%C3%A2-abolishes-naloxone-precipitated-conditioned-place-aversion-in-morphine-dependent-mice
#6
Jing Wang, Min Li, Ping Wang, Yunhong Zha, Zhi He, Zicheng Li
Addictive substances mediate positive and negative states promoting compulsive drug use. However, substrates for aversive effects of drugs are not fully understood. We found that inactivation of the lateral habenula (LHb) by microinjection of tetrodotoxin (TTX) abolished naloxone-precipitated conditioned place aversion (CPA) in morphine-dependent mice. We also found that lateral habenular administration of KN-62, a specific inhibitor for calcium/calmodulin dependent protein kinase II (CaMKII), abolished naloxone-precipitated CPA in morphine-dependent mice...
May 17, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28523735/variability-in-prescription-opioid-intake-and-reinforcement-amongst-129-substrains
#7
Susan M Jimenez, Aiden F Healy, Michal A Coelho, Chelsea N Brown, Tod E Kippin, Karen K Szumlinski
Opioid abuse in the United States has reached epidemic proportions, with treatment admissions and deaths associated with prescription opioid abuse quadrupling over the past 10 years. Although genetics are theorized to contribute substantially to inter-individual variability in the development, severity, and treatment outcomes of opioid abuse/addiction, little direct preclinical study has focused on the behavioral genetics of prescription opioid reinforcement and drug-taking. Herein, we employed different 129 substrains of mice currently available from The Jackson Laboratory (129S1/SvlmJ, 129X1/SvJ, 129S4/SvJaeJ and 129P3/J) as a model system of genetic variation and assayed mice for oral opioid intake and reinforcement, as well as behavioral and somatic signs of dependence...
May 19, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/28523287/modeling-risky-decision-making-in-nonhuman-animals-shared-core-features
#8
Sarah R Heilbronner
Understanding the neural mechanisms of risky decision-making is critical to developing appropriate treatments for psychiatric disorders, problem gambling, and addiction to drugs of abuse. Probing neurobiological mechanisms requires the use of nonhuman animal models (particularly rhesus macaques, rats, and mice). However, there is considerable variation across species in risk preferences. Nevertheless, there are shared core features of risky decision-making present across species. As demonstrated with a wide variety of behavioral paradigms, modulators of risk preference observed in humans are readily replicated in model species...
August 2017: Current Opinion in Behavioral Sciences
https://www.readbyqxmd.com/read/28523226/interpersonal-early-life-trauma-alters-amygdala-connectivity-and-sustained-attention-performance
#9
Francesca C Fortenbaugh, Vincent Corbo, Victoria Poole, Regina McGlinchey, William Milberg, David Salat, Joseph DeGutis, Michael Esterman
INTRODUCTION: Interpersonal early life trauma (I-ELT) is associated with a myriad of functional impairments in adulthood, increased risk of drug addiction, and neuropsychiatric disorders. While deficits in emotional regulation and amygdala functioning are well characterized, deficits in general cognitive functioning have also been documented. However, the neural underpinnings of cognitive dysfunction in adults with a history of I-ELT and the potential relationship between amygdala-based functional connectivity and behavioral performance are currently poorly understood...
May 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28521732/the-berlin-inventory-of-gambling-behavior-screening-big-s-validation-using-a-clinical-sample
#10
Martin Wejbera, Kai W Müller, Jan Becker, Manfred E Beutel
BACKGROUND: Published diagnostic questionnaires for gambling disorder in German are either based on DSM-III criteria or focus on aspects other than life time prevalence. This study was designed to assess the usability of the DSM-IV criteria based Berlin Inventory of Gambling Behavior Screening tool in a clinical sample and adapt it to DSM-5 criteria. METHODS: In a sample of 432 patients presenting for behavioral addiction assessment at the University Medical Center Mainz, we checked the screening tool's results against clinical diagnosis and compared a subsample of n=300 clinically diagnosed gambling disorder patients with a comparison group of n=132...
May 18, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28521241/cognitive-avoidance-and-aversive-cues-related-to-tobacco-in-male-smokers
#11
Ji Sun Hong, Sun Mi Kim, Hye Yeon Jung, Kyoung Doo Kang, Kyung Joon Min, Doug Hyun Han
BACKGROUND: Treatment using aversive conditioning has been suggested for smoking cessation. The efficacy of this method is thought to be associated with cognitive avoidance. We compare differences in avoidance traits and patterns of associated brain activation in response to cues that induce cravings versus aversion between smokers and non-smokers. METHODS: Fifteen smokers and fifteen non-smokers completed cue reactivity tasks while undergoing functional magnetic resonance imaging (fMRI) to examine brain responses to craving-inducing cues (Cr) and aversion-inducing cues (Av)...
May 11, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28520985/warning-statements-and-safety-practices-among-manufacturers-and-distributors-of-electronic-cigarette-liquids-in-the-united-states
#12
Pebbles Fagan, Pallav Pokhrel, Thaddeus A Herzog, Mignonne C Guy, Kari-Lyn K Sakuma, Dennis R Trinidad, Kevin Cassel, Dorothy Jorgensen, Tania Lynch, Jamie Q Felicitas-Perkins, Sherilyn Palafox, Faith Hamamura, Sarah Maloney, Kaylah Degree, Kymberle Sterling, Eric Moolchan, Mark S Clanton, Thomas Eissenberg
Introduction.: Prior to the Food and Drug Administration's (FDA) regulation of electronic cigarettes and warning statements related to nicotine addiction, there was no critical examination of manufacturer/distributor voluntary practices that could potentially inform FDA actions aimed to protect consumers. This study examined the content of warning statements and safety characteristics of electronic cigarette liquid bottles using a national sample. Methods.: Research staff randomly selected four electronic cigarette liquid manufacturers/distributors from four U...
May 18, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28517956/the-longitudinal-association-between-anxiety-and-internet-addiction-in-adolescence-the-moderating-effect-of-classroom-extraversion
#13
Vasileios Stavropoulos, Rapson Gomez, Eloisa Steen, Charlotte Beard, Lucas Liew, Mark D Griffiths
Background and aims The risk effect of anxiety on addictive behaviors, including Internet addiction (IA), has repeatedly been highlighted in the international literature. However, there is a lack of longitudinal studies examining this association in relation to proximal context effects, particularly in adolescence. Such findings would shed light on potential age- and proximal context-related variations in the anxiety-IA association that could better inform IA prevention and intervention initiatives. Methods In this study, 648 adolescents, embedded in 34 classrooms, were assessed at the age of 16 and again at the age of 18 to examine the effect of anxiety on IA behaviors in relation to the average level of classroom extraversion...
May 18, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28516445/role-of-the-endocannabinoid-system-in-vertebrates-emphasis-on-the-zebrafish-model
#14
REVIEW
Francesca Oltrabella, Adam Melgoza, Brian Nguyen, Su Guo
The endocannabinoid system (eCBs), named after the plant Cannabis sativa, comprises cannabinoid receptors, endogenous ligands known as "endocannabinoids", and enzymes involved in the biosynthesis and degradation of these ligands, as well as putative transporters for these ligands. ECBs proteins and small molecules have been detected in early embryonic stages of many vertebrate models. As a result, cannabinoid receptors and endogenous as well as exogenous cannabinoids influence development and behavior in many vertebrate species...
May 17, 2017: Development, Growth & Differentiation
https://www.readbyqxmd.com/read/28515838/passion-for-academics-and-problematic-health-behaviors
#15
Alexander T Bureau, Selen Razon, Bryan K Saville, Umit Tokac, Lawrence W Judge
According to the Dualistic Model of Passion (39), passion entails valuing, liking, and spending time on an activity. The Dualistic Model also posits two types of passion for activities: harmonious passion (individual voluntarily engages in the activity) and obsessive passion (individual is compelled to engage in the activity). The purpose of the present study was to examine the possible links between college students' passion for academic activities and problematic health behaviors including smoking, excessive drinking, exercise addiction, disordered eating, and sleepiness, which is a possible indicator of sleep deprivation...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28513227/temporal-relationship-of-sex-risk-behaviors-and-substance-use-severity-among-men-in-substance-use-treatment
#16
Howard Newville, James L Sorensen, Mary Hatch-Maillette, Donald A Calsyn
Sex risk behaviors and substance use are intertwined. Many men continue to engage in high-risk sexual behaviors even when enrolled in substance use disorder (SUD) treatment. We hypothesized that changes in sex risk behaviors would coincide with changes in drug/alcohol use severity among men in SUD treatment. During an HIV risk-reduction trial, men in methadone maintenance and outpatient drug-free treatment (N = 359) completed assessments at baseline and six months after. We assessed changes in sex risk and substance use severity, using the Addiction Severity Index-Lite (ASI-Lite), controlling for treatment condition...
May 17, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28513104/novelty-seeking-and-reward-dependence-related-large-scale-brain-networks-functional-connectivity-variation-during-salience-expectancy
#17
Shijia Li, Liliana Ramona Demenescu, Catherine M Sweeney-Reed, Anna Linda Krause, Coraline D Metzger, Martin Walter
A salience network (SN) anchored in the anterior insula (AI) and dorsal anterior cingulate cortex (dACC) plays a key role in switching between brain networks during salience detection and attention regulation. Previous fMRI studies have associated expectancy behaviors and SN activation with novelty seeking (NS) and reward dependence (RD) personality traits. To address the question of how functional connectivity (FC) in the SN is modulated by internal (expectancy-related) salience assignment and different personality traits, 68 healthy participants performed a salience expectancy task using functional magnetic resonance imaging, and psychophysiological interaction analysis (PPI) was conducted to determine salience-related connectivity changes during these anticipation periods...
May 17, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28512435/the-role-of-self-esteem-and-fear-of-negative-evaluation-in-compulsive-buying
#18
Roberta Biolcati
Compulsive buying is a relatively new addictive disorder that interferes with everyday functioning and may result in serious psychological and financial problems (1). A very few data are currently available regarding this behavioral addiction. This study investigated gender differences in the relationships between contingent self-esteem (CSE), fear of negative evaluation (FNE), and compulsive buying. Participants included 240 Italian adults (170 females, M age = 33.80) who responded to self-report questionnaires...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28512009/combining-d-cycloserine-with-appetitive-extinction-learning-modulates-amygdala-activity-during-recall
#19
Claudia Ebrahimi, Stefan P Koch, Eva Friedel, Ilsoray Crespo, Thomas Fydrich, Andreas Ströhle, Andreas Heinz, Florian Schlagenhauf
Appetitive Pavlovian conditioning plays a crucial role in the pathogenesis of drug addiction and conditioned reward cues can trigger craving and relapse even after long phases of abstinence. Promising preclinical work showed that the NMDA-receptor partial agonist D-cycloserine (DCS) facilitates Pavlovian extinction learning of fear and drug cues. Furthermore, DCS-augmented exposure therapy seems to be beneficial in various anxiety disorders, while the supposed working mechanism of DCS during human appetitive or aversive extinction learning is still not confirmed...
May 13, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28510498/deficits-in-go-no-go-task-performance-in-male-undergraduate-high-risk-alcohol-users-are-driven-by-speeded-responding-to-go-stimuli
#20
Xin Zhao, Wang Qian, Lily Fu, Joseph H R Maes
BACKGROUND: Response disinhibition plays an important role in addictive behaviors. However, results of studies on the performance on response inhibition tasks of individuals evidencing potentially problematic levels of alcohol drinking are mixed. OBJECTIVES: We assessed conditions under which persons with a relatively high risk of alcohol dependence show inhibition deficits in such tasks and investigated the nature of those deficits. METHODS: Fifty-eight male undergraduate students, 27 of which were high-risk drinkers according to the Alcohol Use Disorders Identification Test, performed a go/no-go inhibition task with differing percentages of no-go trials (50% vs...
February 17, 2017: American Journal of Drug and Alcohol Abuse
keyword
keyword
73741
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"