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Behavioral Addiction

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https://www.readbyqxmd.com/read/28921780/factors-associated-with-attrition-in-substance-using-patients-enrolled-in-an-intensive-outpatient-program
#1
James Mckowen, Nicholas Carrellas, Courtney Zulauf, Emin Nalan Ward, Ronna Fried, Timothy Wilens
BACKGROUND AND OBJECTIVES: Data suggest individuals with substance use disorders (SUD) have high rates of attrition from treatment and exhibit impairments on measures of executive functioning (EF). The primary aim of this pilot study was to investigate if EF is associated with attrition from a 1 month intensive outpatient program (IOP) for SUD, and examine the feasibility of implementing the project. METHODS: Baseline neurocognitive functioning was assessed by the Cambridge Neuropsychological Test Automated Battery (CANTAB) and the self-reported Behavior Rating Inventory of Executive Functioning (BRIEF-A) questionnaire...
September 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28920521/implementing-evidence-based-smoking-cessation-treatment-in-psychosocial-care-units-caps-in-brazil
#2
João Mauricio Castaldelli-Maia, Nilson R da Silva, Marta Rd Campos, Helena F Moura, Gustavo Zabert, Beatriz M Champagne, Katherine E Kemper, J Taylor Hays
BACKGROUND: The prevalence of smoking among mental health and addiction (MHA) patients is 3 times higher than it is in the general population, yet this patient population has received little help to combat smoking. Considering this, psychosocial care centers (CAPS - Centros de Atenção Psicossocial) are strategic locations for integrating tobacco dependence treatment (TDT) into existing treatment activities. METHODS: Our team provided an 8-hour training package to the staff of CAPS that have not been providing specialized TDT for smokers...
September 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28919445/cognitive-effects-of-labeled-addictolytic-medications
#3
REVIEW
Camille Noélie Pujol, Cecilia Paasche, Vincent Laprevote, Benoit Trojak, Pierre Vidailhet, Elisabeth Bacon, Laurence Lalanne
INTRODUCTION: Alcohol, tobacco, and illegal drug usage is pervasive throughout the world, and abuse of these substances is a major contributor to the global disease burden. Many pharmacotherapies have been developed over the last 50years to target addictive disorders. While the efficacy of these pharmacotherapies is largely recognized, their cognitive impact is less known. However, all substance abuse disorders are known to promote cognitive disorders like executive dysfunction and memory impairment...
September 14, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28918540/a-mixed-method-assessment-of-a-pilot-peer-advocate-intervention-for-rural-gender-and-sexual-minorities
#4
Cathleen E Willging, Audrey Harkness, Tania Israel, David Ley, Patricia S Hokanson, Catherine DeMaria, Aaron Joplin, Verida Smiley
Mental health disparities affect lesbian, gay, bisexual, transgender, and queer (LGBTQ) people in rural America. There are few empirically-based mental health interventions for this population. This exploratory study uses a mixed-method approach to assess implementation issues related to the feasibility, acceptability, appropriateness, and preliminary impacts of a novel peer-based intervention designed to enhance support and treatment engagement among rural LGBTQ people with mental distress and/or addiction issues...
September 16, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28918457/effects-of-menthol-and-its-interaction-with-nicotine-conditioned-cue-on-nicotine-seeking-behavior-in-rats
#5
Erin Harrison, Lisa Biswas, Ramachandram Avusula, Meiyu Zhang, Yongzhen Gong, Xiu Liu
RATIONALE: Increasing clinical evidence suggests that menthol, a significant flavoring additive in tobacco products, may contribute to smoking and nicotine dependence. Relapse to smoking behavior presents a formidable challenge for the treatment of tobacco addiction. An unresolved issue is whether the mentholation of tobacco products precipitates relapse to tobacco use in abstinent smokers. OBJECTIVES: The present study examined the effects of menthol on the perseverance and relapse of nicotine-seeking behavior in rats...
September 16, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28912702/altered-white-matter-integrity-in-smokers-is-associated-with-smoking-cessation-outcomes
#6
Peiyu Huang, Zhujing Shen, Chao Wang, Wei Qian, Huan Zhang, Yihong Yang, Minming Zhang
Smoking is a significant cause of preventable mortality worldwide. Understanding the neural mechanisms of nicotine addiction and smoking cessation may provide effective targets for developing treatment strategies. In the present study, we explored whether smokers have white matter alterations and whether these alterations are related to cessation outcomes and smoking behaviors. Sixty-six smokers and thirty-seven healthy non-smokers were enrolled. The participants underwent magnetic resonance imaging scans and smoking-related behavioral assessments...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28911965/physiological-roles-of-cns-muscarinic-receptors-gained-from-knockout-mice
#7
REVIEW
Morgane Thomsen, Gunnar Sørensen, Ditte Dencker
Because the five muscarinic acetylcholine receptor subtypes have overlapping distributions in many CNS tissues, and because ligands with a high degree of selectivity for a given subtype long remained elusive, it has been difficult to determine the physiological functions of each receptor. Genetically engineered knockout mice, in which one or more muscarinic acetylcholine receptor subtype has been inactivated, have been instrumental in identifying muscarinic receptor functions in the CNS, at the neuronal, circuit, and behavioral level...
September 11, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28910215/substance-misuse-is-associated-with-increased-psychiatric-severity-among-treatment-seeking-individuals-with-borderline-personality-disorder
#8
Laura M Heath, Lise Laporte, Joel Paris, Kevin Hamdullahpur, Kathryn J Gill
Despite high prevalence rates of concurrent borderline personality disorder (BPD) and substance use disorders (SUDs), little is known about the impact of substance misuse on the presentation of BPD. Sixty-five individuals with BPD were assessed at intake and at 3- and 6-month follow-up. Assessment included validated instruments such as the Addiction Severity Index and the Revised Symptom Checklist (SCL-90-R). Over half (58.5%) of individuals entering treatment were currently misusing substances. Substance misuse was associated with more legal and employment problems, greater mood disturbance, impulsivity, and psychiatric severity, including almost all SCL-90-R subscales...
September 14, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28905734/swift-and-certain-proportionate-and-consistent-key-values-of-urine-drug-test-consequences-for-probationers
#9
Amy B Cadwallader
Traditionally, urine drug testing (UDT) in the correctional population (both prison and community corrections) has been infrequent, is scheduled, and has a high possibility of delayed results. Of practical relevance is that scheduled testing is ineffective for identifying drug misuse. Of ethical relevance is that consequences of positive scheduled tests can be unpredictable-in the form of overly severe punishment or a lack of treatment options-and that the scheduled testing paradigm is a poor way to change behaviors...
September 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28904544/changing-beliefs-and-behaviors-related-to-sexually-transmitted-diseases-in-vulnerable-women-a-qualitative-study
#10
Zahra Boroumandfar, Masoud Kianpour, Ali Zargham, Samereh Abdoli, Katayoun Tayeri, Mehrdad Salehi, Godratollah Momeni, Farzin Khorvash
BACKGROUND: The first step in health education is awareness of the people and their acceptance to change their behavior. Therefore, the aim of this study was to investigate the effects of empowerment program towards the concept of self-care and prevention of sexually transmitted diseases (STDs) in women at risk of STDs. MATERIALS AND METHODS: The present study was conducted as a qualitative approach (step of action and observation of an action) by using conventional content analysis method...
July 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28900372/psychological-stress-has-a-higher-rate-of-developing-addictive-behaviors-compared-to-physical-stress-in-rat-offspring
#11
Masoud Nazeri, Arezoo Ebrahimi, Iraj Aghaei, Samaneh Ghotbi Ravandi, Mohammad Shabani
Prenatal stress could have great influence on development of offspring and might alter cognitive function and other physiological processes of children. The current study was conducted to study the effect of physical or psychological prenatal stress on addictive and anxiety-like behavior of male and female offspring during their adolescence period (postnatal day (PND) 40). Adult female rats were exposed to physical (swimming) or psychological (observing another female rat swimming) stress from day six of gestation for 10 days...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28899796/once-is-too-much-early-development-of-the-opponent-process-in-taste-reactivity-behavior-is-associated-with-later-escalation-of-cocaine-self-administration-in-rats
#12
Elizabeth M Colechio, Danielle N Alexander, Caesar G Imperio, Kelsey Jackson, Patricia S Grigson
Evidence suggests that the addiction process may begin immediately in some vulnerable subjects. Specifically, some rats have been shown to exhibit aversive taste reactivity (gapes) following the intraoral delivery of a cocaine-predictive taste cue after as few as 1 to 2 taste-drug pairings. After only 3 to 4 trials, the number of gapes becomes a reliable predictor of later cocaine self-administration. Given that escalation of drug-taking behavior over time is recognized as a key feature of substance use disorder (SUD) and addiction, the present study examined the relationship between early aversion to the cocaine-predictive flavor cue and later escalation of cocaine self-administration in an extended-access paradigm...
September 9, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28898309/-psychiatric-complications-of-cannabis-use
#13
Adriana V Bulacia
atural and synthetic cannabinoids modify the modulatory activity of the endocannabinoid system. Psychiatric complications induced by cannabis are analyzed, i.e. those that start with intoxication but persist beyond the removal of the drug (cognitive, psychotic and anxiety disorders) and the development of addictive behavior. Adolescence is the period of greatest vulnerability to cognitive impact. Cannabis-induced psychosis has been linked to consumption of high concentration of tetrahydrocannabinol and personality traits of anxiety and somatization...
November 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28895569/the-effects-of-the-monoamine-stabilizer-osu6162-on-binge-like-eating-and-cue-controlled-food-seeking-behavior-in-rats
#14
K Feltmann, C Giuliano, B J Everitt, P Steensland, J Alsiö
Binge eating disorder (BED) is characterized by recurring episodes of excessive consumption of palatable food and an increased sensitivity to food cues. Patients with BED display an addiction-like symptomatology and the dopamine system might be a potential treatment target. The clinically safe monoamine stabilizer (-)-OSU6162 (OSU6162) restores dopaminergic dysfunction in long-term alcohol drinking rats and shows promise as a novel treatment for alcohol use disorder. Here, the effects of OSU6162 on consummatory (binge-like eating) and appetitive (cue-controlled seeking) behavior motivated by chocolate-flavored sucrose pellets were evaluated in non-food-restricted male Lister Hooded rats...
September 12, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28894547/a-novel-therapy-for-cocaine-dependence-during-abstinence-a-randomized-clinical-trial
#15
Bijan Pirnia, Ali Reza Moradi, Kambiz Pirnia, Parisa Kolahi, Rasool Roshan
BACKGROUND: Topiramate is an anticonvulsant drug and an ideal candidate for reducing the craving in people relying on cocaine. Contingency management is one of the common therapies in the domain of addiction. OBJECTIVE: The present study aimed to evaluate and compare three medication methods of Topiramate (TPM), Contingency Management (CM) and the combined TPM treatment and cash intervention on craving during abstinence. METHODS: This randomized clinical trial was conducted at Bijan Center for Substance Abuse Treatment in Tehran, Iran, from December 15, 2014 to November 20, 2015...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28893726/a-web-based-lifestyle-medicine-curriculum-facilitating-education-about-lifestyle-medicine-behavioral-change-and-health-care-outcomes
#16
Elizabeth Pegg Frates, Ryan C Xiao, Deepa Sannidhi, Yasamina McBride, Tracie McCargo, Theodore A Stern
BACKGROUND: Lifestyle medicine is the science and application of healthy lifestyles as interventions for the prevention and treatment of disease, and has gained significant momentum as a specialty in recent years. College is a critical time for maintenance and acquisition of healthy habits. Longer-term, more intensive web-based and in-person lifestyle medicine interventions can have a positive effect. Students who are exposed to components of lifestyle medicine in their education have improvements in their health behaviors...
September 11, 2017: JMIR Medical Education
https://www.readbyqxmd.com/read/28893670/acute-psychophysiological-stress-impairs-human-associative-learning
#17
M R Ehlers, R M Todd
Addiction is increasingly discussed asa disorder of associative learning processes, with both operant and classical conditioning contributing to the development of maladaptive habits. Stress has long been known to promote drug taking and relapse and has further been shown to shift behavior from goal-directed actions towards more habitual ones. However, it remains to be investigated how acute stress may influence simple associative learning processes that occur before a habit can be established. In the present study, healthy young adults were exposed to either acute stress or a control condition half an hour before performing simple classical and operant conditioning tasks...
September 8, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28893336/problematic-internet-use-in-gamblers-impact-on-clinical-and-cognitive-measures
#18
Samuel R Chamberlain, Sarah A Redden, Eric Leppink, Jon E Grant
OBJECTIVE: Gambling is a commonplace phenomenon, existing along a continuum from occasional gambling to functionally impairing gambling disorder. The internet may act as a conduit for some gambling behaviors. The impact of problematic internet use on clinical and cognitive features relevant to gambling has received little research attention. METHODS: A total of 206 adults aged 18-30 years who gamble at least five times per year were recruited from the general community and undertook detailed clinical and cognitive assessments...
September 12, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28892737/misdeed-of-the-need-towards-computational-accounts-of-transition-to-addiction
#19
REVIEW
Mehdi Keramati, Serge H Ahmed, Boris S Gutkin
Drug addiction is a complex behavioral and neurobiological disorder which, in an emergent brain-circuit view, reflects a loss of prefrontal top-down control over subcortical circuits governing drug-seeking and drug-taking. We first review previous computational accounts of addiction, focusing on cocaine addiction and on prevalent dopamine-based positive-reinforcement and negative-reinforcement computational models. Then, we discuss a recent computational proposal that the progression to addiction is unlikely to result from a complete withdrawal of the goal-oriented decision system in favor the habitual one...
September 8, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28892721/glial-and-neuroinflammatory-targets-for-treating-substance-use-disorders
#20
REVIEW
Ryan K Bachtell, Jermaine D Jones, Keith G Heinzerling, Patrick M Beardsley, Sandra D Comer
BACKGROUND: The plenary session at the 2016 Behavior, Biology and Chemistry: Translational Research in Addiction Conference focused on glia as potential players in the development, persistence and treatment of substance use disorders. Glia partake in various functions that are important for healthy brain activity. Drugs of abuse alter glial cell activity producing several perturbations in brain function that are thought to contribute to behavioral changes associated with substance use disorders...
August 31, 2017: Drug and Alcohol Dependence
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