Young-Jung Kim, Wun-A Kook, Shi-Xun Ma, Bo-Ram Lee, Yong-Hyun Ko, Seon-Kyung Kim, Youyoung Lee, Jae-Gyeong Lee, Sooyeun Lee, Kyeong-Man Kim, Seok-Yong Lee, Choon-Gon Jang
Novel psychoactive substances (NPSs) are new psychotropic drugs designed to evade substance regulatory policies. 25E-NBOMe (2-(4-ethyl-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine) has recently been identified as an NPS, and its recreational misuse has been reported to be rapidly increasing. However, the psychopharmacological effects and mechanisms of 25E-NBOMe have not been studied. We examined the abuse potential of 25E-NBOMe using the conditioned place preference in male mice and self-administration paradigms in male rats...
March 29, 2024: Archives of Pharmacal Research