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https://www.readbyqxmd.com/read/27913366/deepr-a-convolutional-net-for-medical-records
#1
Phuoc Nguyen, Truyen Tran, Nilmini Wickramasinghe, Svetha Venkatesh
Feature engineering remains a major bottleneck when creating predictive systems from electronic medical records. At present, an important missing element is detecting predictive regular clinical motifs from irregular episodic records. We present Deepr (short for Deep record), a new end-to-end deep learning system that learns to extract features from medical records and predicts future risk automatically. Deepr transforms a record into a sequence of discrete elements separated by coded time gaps and hospital transfers...
December 1, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/27912825/next-generation-sequencing-of-lung-cancers-lessons-learned-and-future-directions
#2
REVIEW
Siddhartha Devarakonda, Ashiq Masood, Ramaswamy Govindan
Targeted therapies and immune checkpoint inhibitors have significantly improved outcomes in a sizable fraction of patients with metastatic non-small cell lung cancer. Nevertheless, a majority of patients with lung cancer continue to have poor outcomes. The ability to comprehensively characterize the genomic alterations in various subtypes of lung cancer has the potential to transform cancer care by facilitating the identification of novel treatment strategies. The objective of this review is to summarize key findings from recent studies that have sequenced a large number of lung cancer samples and discuss the diagnostic, prognostic, and therapeutic relevance of these findings...
February 2017: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/27909030/the-college-science-learning-cycle-an-instructional-model-for-reformed-teaching
#3
Michelle Withers
Finding the time for developing or locating new class materials is one of the biggest barriers for instructors reforming their teaching approaches. Even instructors who have taken part in training workshops may feel overwhelmed by the task of transforming passive lecture content to engaging learning activities. Learning cycles have been instrumental in helping K-12 science teachers design effective instruction for decades. This paper introduces the College Science Learning Cycle adapted from the popular Biological Sciences Curriculum Study 5E to help science, technology, engineering, and mathematics faculty develop course materials to support active, student-centered teaching approaches in their classrooms...
2016: CBE Life Sciences Education
https://www.readbyqxmd.com/read/27909020/the-design-and-transformation-of-biofundamentals-a-nonsurvey-introductory-evolutionary-and-molecular-biology-course
#4
Michael W Klymkowsky, Jeremy D Rentsch, Emina Begovic, Melanie M Cooper
Many introductory biology courses amount to superficial surveys of disconnected topics. Often, foundational observations and the concepts derived from them and students' ability to use these ideas appropriately are overlooked, leading to unrealistic expectations and unrecognized learning obstacles. The result can be a focus on memorization at the expense of the development of a meaningful framework within which to consider biological phenomena. About a decade ago, we began a reconsideration of what an introductory course should present to students and the skills they need to master...
2016: CBE Life Sciences Education
https://www.readbyqxmd.com/read/27908032/decision-fractional-fast-fourier-transform-doppler-compensation-in-underwater-acoustic-orthogonal-frequency-division-multiplexing
#5
Xuefei Ma, Caiyun Zheng
A method of compensating for Doppler distortions of underwater acoustic channels for orthogonal frequency division multiplexing (OFDM) signals is proposed. This method is based on symbol rebuilding. OFDM symbol rebuilding is performed after fractional fast Fourier transform (F-FFT) processing. A stochastic gradient-type adaptive algorithm is designed to learn the combiner weights for detection. Synthetic data and experimental data from a recent mobile acoustic communication experiment are used to demonstrate the performance of the proposed method, which represents a significant improvement over the F-FFT detection technique...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27906001/evolution-of-changes-in-cognitive-function-after-the-initiation-of-antiretroviral-therapy
#6
Borja Mora-Peris, Elizabeth Stevens, Francesca Ferretti, Jonathan Underwood, Stephen Taylor, Alan Winston
BACKGROUND: Cognitive function is reported to improve after the initiation of combination antiretroviral therapy (cART). Data on the evolution of such changes are limited. We assessed the dynamics of changes in cognitive parameters, in HIV-positive subjects initiating cART. METHODS: Cognitive function in seven domains was evaluated for HIV-infected patients without clinically significant cognitive impairment prior to the initiation of cART, and 24 and 48 weeks after...
April 14, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905224/vision-of-success
#7
Gloria Rowland
I never wanted to be a head of midwifery - I found myself in the position by default after I took a secondment role at a London trust that had previously been placed in special measures. I enjoyed the challenge and found my passion as a transformational leader. I reflected on my leadership approach, learned a lot and adopted new techniques for managing people.
December 1, 2016: Nursing Management (Harrow)
https://www.readbyqxmd.com/read/27903731/memory-transformation-enhances-reinforcement-learning-in-dynamic-environments
#8
Adam Santoro, Paul W Frankland, Blake A Richards
: Over the course of systems consolidation, there is a switch from a reliance on detailed episodic memories to generalized schematic memories. This switch is sometimes referred to as "memory transformation." Here we demonstrate a previously unappreciated benefit of memory transformation, namely, its ability to enhance reinforcement learning in a dynamic environment. We developed a neural network that is trained to find rewards in a foraging task where reward locations are continuously changing...
November 30, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27892817/creating-the-medical-school-of-the-future-through-incremental-curricular-transformation-the-stanford-healthcare-innovations-and-experiential-learning-directive-shield
#9
Steven Lin, Kim Osborn, Amelia Sattler, Ian Nelligan, David Svec, Alistair Aaronson, Erika Schillinger
No abstract text is available yet for this article.
November 28, 2016: Education for Primary Care
https://www.readbyqxmd.com/read/27878849/leading-change-a-concept-analysis
#10
Heather V Nelson-Brantley, Debra J Ford
AIM: To report an analysis of the concept of leading change. BACKGROUND: Nurses have been called to lead change to advance the health of individuals, populations and systems. Conceptual clarity about leading change in the context of nursing and healthcare systems provides an empirical direction for future research and theory development that can advance the science of leadership studies in nursing. DESIGN: Concept analysis. DATA SOURCES: CINAHL, PubMed, PsycINFO, Psychology and Behavioral Sciences Collection, Health Business Elite and Business Source Premier databases were searched using the terms: leading change, transformation, reform, leadership and change...
November 23, 2016: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/27872871/microscopic-medical-image-classification-framework-via-deep-learning-and-shearlet-transform
#11
Hadi Rezaeilouyeh, Ali Mollahosseini, Mohammad H Mahoor
Cancer is the second leading cause of death in US after cardiovascular disease. Image-based computer-aided diagnosis can assist physicians to efficiently diagnose cancers in early stages. Existing computer-aided algorithms use hand-crafted features such as wavelet coefficients, co-occurrence matrix features, and recently, histogram of shearlet coefficients for classification of cancerous tissues and cells in images. These hand-crafted features often lack generalizability since every cancerous tissue and cell has a specific texture, structure, and shape...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27872371/statistical-learning-in-songbirds-from-self-tutoring-to-song-culture
#12
Olga Fehér, Iva Ljubičić, Kenta Suzuki, Kazuo Okanoya, Ofer Tchernichovski
At the onset of vocal development, both songbirds and humans produce variable vocal babbling with broadly distributed acoustic features. Over development, these vocalizations differentiate into the well-defined, categorical signals that characterize adult vocal behaviour. A broadly distributed signal is ideal for vocal exploration, that is, for matching vocal production to the statistics of the sensory input. The developmental transition to categorical signals is a gradual process during which the vocal output becomes differentiated and stable...
January 5, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/27870522/critical-domains-of-culturally-relevant-leadership-learning-a-call-to-transform-leadership-programs
#13
Tamara Bertrand Jones, Kathy L Guthrie, Laura Osteen
This chapter introduces the critical domains of culturally relevant leadership learning. The model explores how capacity, identity, and efficacy of student leaders interact with dimensions of campus climate.
December 2016: New Directions for Student Leadership
https://www.readbyqxmd.com/read/27870521/leading-to-transgress-critical-considerations-for-transforming-leadership-learning
#14
Laura Osteen, Kathy L Guthrie, Tamara Bertrand Jones
The culturally relevant leadership learning (CRLL) model is explored through the lens of theory and practice. This creates critical questions to guide leadership educators in the ongoing process of transforming leadership programs.
December 2016: New Directions for Student Leadership
https://www.readbyqxmd.com/read/27870517/culturally-responsive-integrative-learning-environments-a-critical-displacement-approach
#15
Antron D Mahoney
This chapter outlines a critical framework for developing culturally responsive integrative learning environments in leadership education. The framework is grounded in the scholarship of women of color feminism and offers implications for transforming curricular and cocurricular leadership programs.
December 2016: New Directions for Student Leadership
https://www.readbyqxmd.com/read/27865729/improving-the-efficiency-of-dissolved-oxygen-control-using-an-on-line-control-system-based-on-a-genetic-algorithm-evolving-fwnn-software-sensor
#16
Jujun Ruan, Chao Zhang, Ya Li, Peiyi Li, Zaizhi Yang, Xiaohong Chen, Mingzhi Huang, Tao Zhang
This work proposes an on-line hybrid intelligent control system based on a genetic algorithm (GA) evolving fuzzy wavelet neural network software sensor to control dissolved oxygen (DO) in an anaerobic/anoxic/oxic process for treating papermaking wastewater. With the self-learning and memory abilities of neural network, handling the uncertainty capacity of fuzzy logic, analyzing local detail superiority of wavelet transform and global search of GA, this proposed control system can extract the dynamic behavior and complex interrelationships between various operation variables...
November 16, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27857433/method-for-hue-plane-preserving-color-correction
#17
Michal Mackiewicz, Casper F Andersen, Graham Finlayson
Hue plane preserving color correction (HPPCC), introduced by Andersen and Hardeberg [Proceedings of the 13th Color and Imaging Conference (CIC) (2005), pp. 141-146], maps device-dependent color values (RGB) to colorimetric color values (XYZ) using a set of linear transforms, realized by white point preserving 3×3 matrices, where each transform is learned and applied in a subregion of color space, defined by two adjacent hue planes. The hue plane delimited subregions of camera RGB values are mapped to corresponding hue plane delimited subregions of estimated colorimetric XYZ values...
November 1, 2016: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/27856553/crossing-the-threshold-bringing-biological-variation-to-the-foreground
#18
Janet M Batzli, Jennifer K Knight, Laurel M Hartley, April Cordero Maskiewicz, Elizabeth A Desy
Threshold concepts have been referred to as "jewels in the curriculum": concepts that are key to competency in a discipline but not taught explicitly. In biology, researchers have proposed the idea of threshold concepts that include such topics as variation, randomness, uncertainty, and scale. In this essay, we explore how the notion of threshold concepts can be used alongside other frameworks meant to guide instructional and curricular decisions, and we examine the proposed threshold concept of variation and how it might influence students' understanding of core concepts in biology focused on genetics and evolution...
2016: CBE Life Sciences Education
https://www.readbyqxmd.com/read/27856379/templates-as-a-method-for-implementing-data-provenance-in-decision-support-systems
#19
Vasa Curcin, Elliot Fairweather, Roxana Danger, Derek Corrigan
Decision support systems are used as a method of promoting consistent guideline-based diagnosis supporting clinical reasoning at point of care. However, despite the availability of numerous commercial products, the wider acceptance of these systems has been hampered by concerns about diagnostic performance and a perceived lack of transparency in the process of generating clinical recommendations. This resonates with the Learning Health System paradigm that promotes data-driven medicine relying on routine data capture and transformation, which also stresses the need for trust in an evidence-based system...
November 14, 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/27854266/using-technology-bioinformatics-and-health-informatics-approaches-to-improve-learning-experiences-in-optometry-education-research-and-practice
#20
REVIEW
Vivek K Gupta, Veer B Gupta
Rapid advances in ocular diagnostic approaches and emerging links of pathological changes in the eye with systemic disorders have widened the scope of optometry as the front line of eye health care. Expanding professional requirements stipulate that optometry students get a meticulous training in relevant information and communication technologies (ICT) and various bioinformatics and health informatics software to meet current and future challenges. Greater incorporation of ICT approaches in optometry education can facilitate increased student engagement in shared learning experiences and improve collaborative learning...
November 15, 2016: Healthcare (Basel, Switzerland)
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