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https://www.readbyqxmd.com/read/29230152/development-of-a-mixed-methods-investigation-of-process-and-outcomes-of-community-based-participatory-research
#1
Julie Lucero, Nina Wallerstein, Bonnie Duran, Margarita Alegria, Ella Greene-Moton, Barbara Israel, Sarah Kastelic, Maya Magarati, John Oetzel, Cynthia Pearson, Amy Schulz, Malia Villegas, Emily R White Hat
This article describes a mixed methods study of community-based participatory research (CBPR) partnership practices and the links between these practices and changes in health status and disparities outcomes. Directed by a CBPR conceptual model and grounded in indigenous-transformative theory, our nation-wide, cross-site study showcases the value of a mixed methods approach for better understanding the complexity of CBPR partnerships across diverse community and research contexts. The article then provides examples of how an iterative, integrated approach to our mixed methods analysis yielded enriched understandings of two key constructs of the model: trust and governance...
January 2018: Journal of Mixed Methods Research
https://www.readbyqxmd.com/read/29227399/reflections-on-global-service-learning-in-india
#2
Elizabeth B Simon
Global service learning is an action-oriented, pedagogical approach that engages students in the core values of academic excellence, social relevance, personal transformation, intentional diversity, and cultural competence. The experience of students and nurse educators who have participated in global service-learning trips to India is relayed, along with the healthcare system of several Indian states.
January 2018: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
https://www.readbyqxmd.com/read/29226857/prostate-cancer-detection-using-machine-learning-techniques-by-employing-combination-of-features-extracting-strategies
#3
Lal Hussain, Adeel Ahmed, Sharjil Saeed, Saima Rathore, Imtiaz Ahmed Awan, Saeed Arif Shah, Abdul Majid, Adnan Idris, Anees Ahmed Awan
Prostate is a second leading causes of cancer deaths among men. Early detection of cancer can effectively reduce the rate of mortality caused by Prostate cancer. Due to high and multiresolution of MRIs from prostate cancer require a proper diagnostic systems and tools. In the past researchers developed Computer aided diagnosis (CAD) systems that help the radiologist to detect the abnormalities. In this research paper, we have employed novel Machine learning techniques such as Bayesian approach, Support vector machine (SVM) kernels: polynomial, radial base function (RBF) and Gaussian and Decision Tree for detecting prostate cancer...
November 28, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/29226224/an-application-of-programmatic-assessment-for-learning-pal-system-for-general-practice-training
#4
Lambert Schuwirth, Nyoli Valentine, Paul Dilena
Aim: Programmatic assessment for learning (PAL) is becoming more and more popular as a concept but its implementation is not without problems. In this paper we describe the design principles behind a PAL program in a general practice training context. Design principles: The PAL program was designed to optimise the meaningfulness of assessment information for the registrar and to make him/her use that information to self regulate their learning. The main principles in the program were cognitivist and transformative...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29222297/current-treatment-algorithm-for-the-management-of-patients-with-myelofibrosis-jak-inhibitors-and-beyond
#5
REVIEW
Claire N Harrison, Donal P McLornan
Myelofibrosis (MF) is a heterogeneous disorder characterized by splenomegaly, constitutional symptoms, ineffective hematopoiesis, and an inherent risk of leukemic transformation. The past decade has seen a massive shift in available therapeutic options for our patients and we are learning how and when to use novel agents, either alone or in combination, during the disease course. This has translated into improved management of splenomegaly, significant amelioration in disease-related symptom burden for many, and may lead to improved survival...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29221534/on-becoming-a-global-citizen-transformative-learning-through-global-health-experiences
#6
Debra K Litzelman, Adrian Gardner, Robert M Einterz, Philip Owiti, Charity Wambui, Jordan C Huskins, Kathleen M Schmitt-Wendholt, Geren S Stone, Paul O Ayuo, Thomas S Inui, Rachel A Umoren
BACKGROUND: Globalization has increased the demand for international experiences in medical education. International experiences improve medical knowledge, clinical skills, and self-development; influence career objectives; and provide insights on ethical and societal issues. However, global health rotations can end up being no more than tourism if not structured to foster personal transformation and global citizenship. OBJECTIVE: We conducted a qualitative assessment of trainee-reported critical incidents to more deeply understand the impact of our global health experience on trainees...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29220308/learning-midlevel-auditory-codes-from-natural-sound-statistics
#7
Wiktor Młynarski, Josh H McDermott
Interaction with the world requires an organism to transform sensory signals into representations in which behaviorally meaningful properties of the environment are made explicit. These representations are derived through cascades of neuronal processing stages in which neurons at each stage recode the output of preceding stages. Explanations of sensory coding may thus involve understanding how low-level patterns are combined into more complex structures. To gain insight into such midlevel representations for sound, we designed a hierarchical generative model of natural sounds that learns combinations of spectrotemporal features from natural stimulus statistics...
December 8, 2017: Neural Computation
https://www.readbyqxmd.com/read/29219070/predicting-human-splicing-branchpoints-by-combining-sequence-derived-features-and-multi-label-learning-methods
#8
Wen Zhang, Xiaopeng Zhu, Yu Fu, Junko Tsuji, Zhiping Weng
BACKGROUND: Alternative splicing is the critical process in a single gene coding, which removes introns and joins exons, and splicing branchpoints are indicators for the alternative splicing. Wet experiments have identified a great number of human splicing branchpoints, but many branchpoints are still unknown. In order to guide wet experiments, we develop computational methods to predict human splicing branchpoints. RESULTS: Considering the fact that an intron may have multiple branchpoints, we transform the branchpoint prediction as the multi-label learning problem, and attempt to predict branchpoint sites from intron sequences...
December 1, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29218876/owl-nets-transforming-owl-representations-for-improved-network-inference
#9
Tiffany J Callahan, William A Baumgartner, Michael Bada, Adrianne L Stefanski, Ignacio Tripodi, Elizabeth K White, Lawrence E Hunter
Our knowledge of the biological mechanisms underlying complex human disease is largely incomplete. While Semantic Web technologies, such as the Web Ontology Language (OWL), provide powerful techniques for representing existing knowledge, well-established OWL reasoners are unable to account for missing or uncertain knowledge. The application of inductive inference methods, like machine learning and network inference are vital for extending our current knowledge. Therefore, robust methods which facilitate inductive inference on rich OWL-encoded knowledge are needed...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29218869/chemical-reaction-vector-embeddings-towards-predicting-drug-metabolism-in-the-human-gut-microbiome
#10
Emily K Mallory, Ambika Acharya, Stefano E Rensi, Peter J Turnbaugh, Roselie A Bright, Russ B Altman
Bacteria in the human gut have the ability to activate, inactivate, and reactivate drugs with both intended and unintended effects. For example, the drug digoxin is reduced to the inactive metabolite dihydrodigoxin by the gut Actinobacterium E. lenta, and patients colonized with high levels of drug metabolizing strains may have limited response to the drug. Understanding the complete space of drugs that are metabolized by the human gut microbiome is critical for predicting bacteria-drug relationships and their effects on individual patient response...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29216788/insights-into-teaching-a-complex-skill-threshold-concepts-and-troublesome-knowledge-in-electroencephalography-eeg
#11
Jeremy J Moeller, Tim Fawns
BACKGROUND: Threshold concepts (TCs) are defined as ideas within a discipline that are often conceptually difficult ("troublesome"), but when learned, transform a learner's understanding. Electroencephalography (EEG) has been recognized as a conceptually difficult field in neurology, and a study of threshold concepts in EEG may provide insights into how it is taught and learned. METHODS: Semi-structured interviews were performed with 12 EEG experts in the US and Canada...
December 7, 2017: Medical Teacher
https://www.readbyqxmd.com/read/29215876/deep-learning-of-atomically-resolved-scanning-transmission-electron-microscopy-images-chemical-identification-and-tracking-local-transformations
#12
Maxim Ziatdinov, Ondrej Dyck, Artem Maksov, Xufan Li, Xiahan Sang, Kai Xiao, Raymond R Unocic, Rama Vasudevan, Stephen Jesse, Sergei V Kalinin
Recent advances in scanning transmission electron and scanning probe microscopies have opened exciting opportunities in probing the materials structural parameters and various functional properties in real space with angstrom-level precision. This progress has been accompanied by an exponential increase in the size and quality of datasets produced by microscopic and spectroscopic experimental techniques. These developments necessitate adequate methods for extracting relevant physical and chemical information from the large datasets, for which a priori information on the structures of various atomic configurations and lattice defects is limited or absent...
December 7, 2017: ACS Nano
https://www.readbyqxmd.com/read/29211049/living-organisms-author-their-read-write-genomes-in-evolution
#13
REVIEW
James A Shapiro
Evolutionary variations generating phenotypic adaptations and novel taxa resulted from complex cellular activities altering genome content and expression: (i) Symbiogenetic cell mergers producing the mitochondrion-bearing ancestor of eukaryotes and chloroplast-bearing ancestors of photosynthetic eukaryotes; (ii) interspecific hybridizations and genome doublings generating new species and adaptive radiations of higher plants and animals; and, (iii) interspecific horizontal DNA transfer encoding virtually all of the cellular functions between organisms and their viruses in all domains of life...
December 6, 2017: Biology
https://www.readbyqxmd.com/read/29210358/computer-aided-assessment-of-breast-density-comparison-of-supervised-deep-learning-and-feature-based-statistical-learning
#14
Songfeng Li, Jun Wei, Heang-Ping Chan, Mark A Helvie, Marilyn A Roubidoux, Yao Lu, Chuan Zhou, Lubomir M Hadjiiski, Ravi K Samala
Breast density is one of the most significant factors that is associated with cancer risk. In this study, our purpose was to develop a supervised deep learning approach for automated estimation of percentage density (PD) on digital mammograms (DM). The input "for processing" DM was first log-transformed, enhanced by a multi-resolution preprocessing scheme, and subsampled to a pixel size of 800µm×800µm from 100µm×100µm. A deep convolutional neural network (DCNN) was trained to estimate a probability map of breast density (PMD) by using a domain adaptation resampling method...
December 6, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29206266/innovative-approach-to-senior-practicum-students
#15
Melissa Golightly, Natalie Kennett, Jacqueline A Stout
BACKGROUND: Traditional senior practicum experiences (SPEs) are microsystem based-they allow senior nursing students the opportunity to build professional nursing competencies as they transition into practice. As health care transformation continues unabated, there is a need to work toward closing the gap between nursing academia and nursing practice. METHOD: A cardiovascular service line created an innovative SPE to better prepare senior nursing students for working as professional nurses in a service line model...
December 1, 2017: Journal of Nursing Education
https://www.readbyqxmd.com/read/29202164/lessons-learned-by-a-founding-dean-college-of-health-and-human-services-at-western-kentucky-university
#16
John A Bonaguro
This article describes the process in the development and implementation of the College of Health and Human Services at Western Kentucky University. Lessons learned and insights gained as an inaugural dean are presented around four main themes: creating a culture of trust and transparency, leaders of change, strategic planning, and cultivating external resources. The application of change theory, transformational leadership, and systems thinking enabled the college to more than double its enrollment and to address critical workforce needs in health and human services...
2017: Journal of Allied Health
https://www.readbyqxmd.com/read/29198475/learning-to-live-with-a-hand-nerve-disorder-a-constructed-grounded-theory
#17
Mark Ashwood, Christina Jerosch-Herold, Lee Shepstone
STUDY DESIGN: Grounded theory. INTRODUCTION: The broader perspective of health offered by the World Health Organization's International Classification of Functioning, Disability and Health has had a significant bearing on how we view the measurement of health outcomes after surgical or therapy interventions for peripheral nerve disorders affecting the hand. The value of the patient's perspective is now recognized and outcomes which reflect this are being advocated in the clinical management and support of this population...
November 29, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/29198094/-from-pastoral-care-to-spiritual-care-transforming-the-conception-of-the-role-of-the-spiritual-care-provider
#18
REVIEW
Michael Schultz, Netta Bentur, Ziv Rei Koren, Gil Bar Sela
Spirituality is a difficult concept to define, one that is often understood differently by different cultures and religious communities. Illness constitutes a dramatic change in the ongoing flow and norms of a person's life, raising questions of the value or meaning of life, questions of self-worth, and questions of forgiveness, to ourselves and others. The profession of spiritual care comes to provide support in these areas. Originally focused on religious care, the profession has shifted to providing care for general spiritual well-being, where professionals care for all patients regardless of religion...
November 2017: Harefuah
https://www.readbyqxmd.com/read/29197716/understanding-organization-transformation-in-evaluation-and-program-planning
#19
Robert L Schalock, Miguel Angel Verdugo, Jos van Loon
Organization transformation is an increasingly important concept and process in human service organizations as they adapt to rapidly changing challenges and opportunities to enhance their effectiveness, efficiency, and sustainability. This article describes a four-component organization transformation model that incorporates transformation pillars, transformation strategies, organization capacity, and organization outputs and outcomes. The article includes examples of the model's use, and concludes with a discussion of valuable lessons learned to date...
November 24, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29196666/sigma-frequency-dependent-motor-learning-in-williams-syndrome
#20
Andrea Berencsi, Róbert Bódizs, Ferenc Gombos, Szandra László, Ilona Kovács
There are two basic stages of fine motor learning: performance gain might occur during practice (online learning), and improvement might take place without any further practice (offline learning). Offline learning, also called consolidation, has a sleep-dependent stage in terms of both speed and accuracy of the learned movement. Sleep spindle or sigma band characteristics affect motor learning in typically developing individuals. Here we ask whether the earlier found, altered sigma activity in a neurodevelopmental disorder (Williams syndrome, WS) predicts motor learning...
December 1, 2017: Scientific Reports
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