keyword
https://read.qxmd.com/read/38533159/intra-abdominal-pressure-measurement-as-a-predictor-of-postoperative-wound-complications-in-patients-undergoing-emergency-laparotomy-a-prospective-observational-study
#1
JOURNAL ARTICLE
Dharmendra Dugar, Sunny Goel
Introduction Elevated intra-abdominal pressure (IAP) hampers the effective functioning of intra- and extra-abdominal organs. Despite the abundance of knowledge, routine measurement of IAP still needs to be widely incorporated in managing at-risk patients. The present study intends to assess the need for IAP measurement on abdominal wound healing in emergency laparotomy patients. Methods This prospective study was carried out over 24 months in patients undergoing emergency laparotomy. The IAP was measured at admission, immediately after surgery, and during the early postoperative period at 6, 12, 24, 48, and 72 hours...
February 2024: Curēus
https://read.qxmd.com/read/38512385/associations-between-hypoglycemia-awareness-status-and-symptoms-of-hypoglycemia-among-adults-with-type-1-or-insulin-treated-type-2-diabetes-using-the-hypo-metrics-smartphone-application
#2
JOURNAL ARTICLE
Gilberte Martine-Edith, Natalie Zaremba, Patrick Divilly, Uffe Søholm, Melanie Broadley, Petra Martina Baumann, Zeinab Mahmoudi, Mikel Gomes, Namam Ali, Evertine J Abbink, Bastiaan E de Galan, Julie Maria Bøggild Brøsen, Ulrik Pedersen-Bjergaard, Allan A Vaag, Rory McCrimmon, Eric Renard, Simon Heller, Mark Evans, Monika Cigler, Julia K Mader, Stephanie Amiel, Jane Speight, Frans Pouwer, Pratik Choudhary
Introduction This study examined associations between hypoglycemia awareness status and hypoglycemia symptoms reported in real-time using the novel Hypo-METRICS smartphone application (app) among adults with insulin-treated type 1 (T1D) or type 2 diabetes (T2D). Methods Adults who experienced at least one hypoglycemic episode in the previous three months were recruited to the Hypo-METRICS study. They prospectively reported hypoglycemia episodes using the app for 10 weeks. Any of eight hypoglycemia symptoms were considered present if intensity was rated between 'A little bit' to 'Very much' and absent if rated 'Not at all'...
March 21, 2024: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/38502256/international-conference-on-photosynthesis-and-hydrogen-energy-research-for-sustainability-2023-in-honor-of-robert-blankenship-gy%C3%A5-z%C3%A5-garab-michael-gr%C3%A3-tzel-norman-h%C3%A3-ner-and-gunnar-%C3%A3-quist
#3
JOURNAL ARTICLE
Rajagopal Subramanyam, Tatsuya Tomo, Julian J Eaton-Rye, Girayhan Yilmaz, Suleyman I Allakhverdiev
The 11th International Photosynthesis Conference on Hydrogen Energy Research and Sustainability 2023 was organized in honor of Robert Blankenship, Győző Garab, Michael Grätzel, Norman Hüner, and Gunnar Öquist, in Istanbul, Türkiye at Bahçeşehir University Future Campus from 03 to 09 July 2023. It was jointly supported by the International Society of Photosynthesis Research (ISPR) and the International Association for Hydrogen Energy (IAHE). In this article we provide brief details of the conference, its events, keynote speakers, and the scientific contribution of scientists honored at this conference...
March 19, 2024: Photosynthesis Research
https://read.qxmd.com/read/38469566/prevalence-and-factors-associated-with-iron-deficiency-anaemia-among-children-aged-6-23-months-in-southwestern-uganda
#4
JOURNAL ARTICLE
Dickson Kajoba, Walufu Ivan Egesa, Solomon Muyombya, Yamile Arias Ortiz, Martin Nduwimana, Grace Ndeezi
Iron deficiency anaemia is still a global public health concern with the highest burden among children 6 to 23 months due to their rapid growth spurt exceeding breastmilk supply. Therefore, nutritional supply is a key source of iron to attain the required nutrients for better growth and development. This was a cross-sectional descriptive study done at Ishaka Adventist Hospital (IAH) and Kampala International University Teaching Hospital (KIUTH) from April to July 2022. Participants were consecutively enrolled in the study...
2024: International Journal of Pediatrics
https://read.qxmd.com/read/38451347/individualised-flow-controlled-ventilation-reduces-applied-mechanical-power-and-improves-ventilation-efficiency-in-a-porcine-intra-abdominal-hypertension-model
#5
JOURNAL ARTICLE
Julia Abram, Patrick Spraider, Julian Wagner, Gabriel Putzer, Manuela Ranalter, Sarah Rinner, Andrea Katharina Lindner, Bernhard Glodny, Tobias Hell, Tom Barnes, Dietmar Enk, Judith Martini
BACKGROUND: Aim of this study was to evaluate feasibility and effects of individualised flow-controlled ventilation (FCV), based on compliance guided pressure settings, compared to standard of pressure-controlled ventilation (PCV) in a porcine intra-abdominal hypertension (IAH) model. The primary aim of this study was to investigate oxygenation. Secondary aims were to assess respiratory and metabolic variables and lung tissue aeration. METHODS: Pigs were randomly assigned to FCV (n = 9) and PCV (n = 9)...
March 7, 2024: Intensive Care Medicine Experimental
https://read.qxmd.com/read/38441232/impact-of-impaired-awareness-of-hypoglycemia-on-glucose-decline-during-and-after-exercise-in-t1d-the-t1dexi-study
#6
JOURNAL ARTICLE
Jorge L Jo Kamimoto, Zoey Li, Robin L Gal, Jessica R Castle, Francis J Doyle, Peter G Jacobs, Corby K Martin, Roy W Beck, Peter Calhoun, Michael C Riddell, Michael R Rickels
OBJECTIVE: To assess whether impaired awareness of hypoglycemia (IAH) affects exercise-associated hypoglycemia in adults with type 1 diabetes (T1D). METHODS: We compared continuous glucose monitoring (CGM)-measured glucose during exercise and for 24-hours following exercise from 95 adults with T1D and IAH (Clarke score ≥4 or ≥1 severe hypoglycemic event within the past year) to 95 'Aware' adults (Clarke score ≤2 and no severe hypoglycemic event within the past year) matched on sex, age, insulin delivery modality, and HbA1c...
March 4, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38431446/incidence-implications-and-predictors-of-abdominal-compartment-syndrome-in-acute-pancreatitis-a-nationwide-analysis
#7
JOURNAL ARTICLE
Ali Jaan, Zouina Sarfraz, Umer Farooq, Sheza Malik, Asad Ur Rahman, Patrick Okolo
BACKGROUND: Acute pancreatitis (AP) often presents with varying severity, with a small fraction evolving into severe AP, and is associated with high mortality. Complications such as intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are intricately associated with AP. OBJECTIVE: To assess the clinical implications and predictors of ACS in AP patients. METHODS: We conducted a retrospective study using the National Inpatient Sample (NIS) database on adult AP patients, further stratified by the presence of concurrent ACS...
February 18, 2024: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://read.qxmd.com/read/38396205/metabolomic-associations-of-impaired-awareness-of-hypoglycaemia-in-type-1-diabetes
#8
JOURNAL ARTICLE
R D M Varkevisser, A Cecil, C Prehn, D Mul, H J Aanstoot, A D Paterson, B H R Wolffenbuttel, M M van der Klauw
This study investigates impaired awareness of hypoglycaemia (IAH), a complication of insulin therapy affecting 20-40% of individuals with type 1 diabetes. The exact pathophysiology is unclear, therefore we sought to identify metabolic signatures in IAH to elucidate potential pathophysiological pathways. Plasma samples from 578 individuals of the Dutch type 1 diabetes biomarker cohort, 67 with IAH and 108 without IAH (NAH) were analysed using the targeted metabolomics Biocrates AbsoluteIDQ p180 assay. Eleven metabolites were significantly associated with IAH...
February 23, 2024: Scientific Reports
https://read.qxmd.com/read/38323079/experimental-pharmacological-approaches-to-reverse-impaired-awareness-of-hypoglycemia-a-review
#9
REVIEW
Hiba Z Hashmi, Ameer Khowaja, Amir Moheet
The colossal global burden of diabetes management is compounded by the serious complication of hypoglycemia. Protective physiologic hormonal and neurogenic counterregulatory responses to hypoglycemia are essential to preserve glucose homeostasis and avert serious morbidity. With recurrent exposure to hypoglycemic episodes over time, these counterregulatory responses to hypoglycemia can diminish, resulting in an impaired awareness of hypoglycemia (IAH). IAH is characterized by sudden neuroglycopenia rather than preceding cautionary autonomic symptoms...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38318959/postoperative-intra-abdominal-hypertension-predicts-worse-hospital-outcomes-in-children-after-cardiac-surgery%C3%AF-a-pilot-study
#10
JOURNAL ARTICLE
Yunyi Zhang, Shuhua Luo, Yuxuan Xie, Yue Wang, Yibing Fang, Shouping Wang, Lijing Deng
OBJECTIVES: To determine the incidence and characteristics of postoperative intra-abdominal hypertension in paediatric patients undergoing open-heart surgery. METHODS: This single-centre study included consecutive children (aged <16 years) who underwent open-heart surgery between July 2020 and February 2021. Patients who entered the study were followed until in-hospital death or hospital discharge. The study consisted of 2 parts. Part I was a prospective observational cohort study, which was designed to discover the association between exposures and IAH...
February 6, 2024: Interdiscip Cardiovasc Thorac Surg
https://read.qxmd.com/read/38302432/burden-of-impaired-awareness-of-hypoglycemia-in-people-with-diabetes-undergoing-hemodialysis
#11
JOURNAL ARTICLE
Hellena Hailu Habte-Asres, Yutong Jiang, Miranda Rosenthal, David Collins Wheeler
INTRODUCTION: Impaired awareness of hypoglycemia (IAH) refers to a diminished capacity to detect hypoglycemia. IAH can result in severe and even life-threatening outcomes for individuals with diabetes, especially those in advanced stages of the disease. This study aimed to assess the prevalence of IAH in people with diabetes on hemodialysis. RESEARCH DESIGN AND METHODS: We conducted a single-center audit to assess the prevalence of IAH using the Clarke questionnaire...
February 1, 2024: BMJ Open Diabetes Research & Care
https://read.qxmd.com/read/38295397/severe-hypoglycemia-and-impaired-awareness-of-hypoglycemia-persist-in-people-with-type-1-diabetes-despite-use-of-diabetes-technology-results-from-a-cross-sectional-survey
#12
JOURNAL ARTICLE
Jennifer L Sherr, Lori M Laffel, Jingwen Liu, Wendy Wolf, Jeoffrey Bispham, Katherine S Chapman, Daniel Finan, Lina Titievsky, Tina Liu, Kaitlin Hagan, Jason Gaglia, Keval Chandarana, Richard Bergenstal, Jeremy Pettus
OBJECTIVE: To determine how diabetes technologies, including continuous glucose monitoring (CGM) and automated insulin delivery (AID) systems, impact glycemic metrics, prevalence of severe hypoglycemic events (SHEs), and impaired awareness of hypoglycemia (IAH) in people with type 1 diabetes in a real-world setting within the U.S. RESEARCH DESIGN AND METHODS: In this retrospective, observational study with cross-sectional elements, participants aged ≥18 years were enrolled from the T1D Exchange Registry/online community...
January 31, 2024: Diabetes Care
https://read.qxmd.com/read/38243952/impaired-awareness-of-hypoglycemia-and-its-risk-factors-among-diabetic-patients-in-jazan-saudi-arabia-a-cross-sectional-study
#13
JOURNAL ARTICLE
Omar Oraibi, Abdulelah Alameer, Mohammed Dalak, Sawsan Alsharif, Shatha Hakami, Mohammed Sumayli, Ayman Shami, Mostafa Mohrag, Mohammed A Madkhali, Mohammed Ali Madkhali, Luai Alhazmi, Majid Darraj
BACKGROUND: Impaired awareness of hypoglycemia (IAH) is related to a three- to sixfold increase in the risk of severe hypoglycemia in adults with type 1 diabetes mellitus (T1D). This study aimed to assess the prevalence of IAH and its risk factors and determine the frequency of hypoglycemic symptoms. OBJECTIVE: This study aimed to assess the prevalence of IAH and its risk factors and determine the frequency of hypoglycemic symptoms. METHODOLOGY: A cross-sectional study was conducted among T1D patients attending Jazan Endocrine and Diabetes Center in Jazan province, Saudi Arabia...
January 11, 2024: Current Diabetes Reviews
https://read.qxmd.com/read/38234699/review-of-the-india-adolescent-health-strategy-in-the-context-of-disease-burden-among-adolescents
#14
JOURNAL ARTICLE
Rakhi Dandona, Anamika Pandey, G Anil Kumar, Monika Arora, Lalit Dandona
BACKGROUND: A nuanced understanding of the health needs of adolescents in the context of the India Adolescent Health Strategy (IAHS) is needed to inform policy interventions for improving the health and well-being of adolescents in India. METHODS: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, we identified the top ten causes of years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs) disaggregated by sex and age group (10-14 and 15-19 years) for India and its states in 2019...
January 2024: Lancet Reg Health Southeast Asia
https://read.qxmd.com/read/38224875/prevalence-and-associations-of-impaired-awareness-of-hypoglycemia-in-a-pediatric-type-1-diabetes-population-the-norwegian-childhood-diabetes-registry
#15
JOURNAL ARTICLE
Håvard Hatle, Torild Skrivarhaug, Marit R Bjørgaas, Bjørn O Åsvold, Torstein B Rø
AIMS: To determine the prevalence and associations of impaired awareness of hypoglycemia (IAH) in pediatric type 1 diabetes. METHODS: Nationwide, population-based cross-sectional study with 51 % participation. Participants (n = 1329; 53 % males) aged 2-19 years (median 13.3) with type 1 diabetes ≥ 6 months (median 4.6 years) self-assessed hypoglycemia awareness with a validated questionnaire ('Clarke')...
January 13, 2024: Diabetes Research and Clinical Practice
https://read.qxmd.com/read/38118427/arteriolar-hyalinosis-predicts-the-onset-of-both-macroalbuminuria-and-impaired-renal-function-in-patients-with-type-2-diabetes
#16
JOURNAL ARTICLE
Akihiko Suzuki, Tatsumi Moriya, Akinori Hayashi, Madoka Matsubara, Takeshi Miyatsuka
INTRODUCTION: Arteriolar hyalinosis (AH) have been shown to be associated with albuminuria and GFR. In this study, we investigated whether or not index of AH (IAH) is a predictor of the onset of macroalbuminuria and impaired renal function (eGFR < 60 mL/min/1.73 m2 [eGFR < 60]) in type 2 diabetic patients with early diabetic nephropathy. METHODS: The study population consisted of 35 patients with type 2 diabetes (25 men; age: 47 ± 9 years; eGFR: 92.7 ± 18...
December 20, 2023: Nephron
https://read.qxmd.com/read/38045663/corneal-confocal-microscopy-identifies-structural-small-fibre-abnormalities-in-an-adolescent-with-type-1-diabetes-and-impaired-awareness-of-hypoglycaemia
#17
Mainak Banerjee, Pradip Mukhopadhyay, Madhurima Basu, Sujoy Ghosh
Impaired awareness of hypoglycaemia (IAH) is present in around 25-40% of individuals with type 1 diabetes mellitus (T1DM). Herein, we present a case of an adolescent with T1DM and IAH who had worse corneal nerve parameters compared to a T1DM adolescent without IAH. Small fibre abnormalities detected by corneal confocal microscopy in an objective easy-to-perform non-invasive test might be a surrogate indicator of underlying autonomic dysfunction in T1DM and IAH.
2023: Journal of the ASEAN Federation of Endocrine Societies
https://read.qxmd.com/read/38010533/high-intensity-interval-training-as-a-novel-treatment-for-impaired-awareness-of-hypoglycaemia-in-people-with-type-1-diabetes-hit4hypos-a-randomised-parallel-group-study
#18
RANDOMIZED CONTROLLED TRIAL
Catriona M Farrell, Alison D McNeilly, Simona Hapca, Paul A Fournier, Timothy W Jones, Andrea Facchinetti, Giacomo Cappon, Daniel J West, Rory J McCrimmon
AIMS/HYPOTHESIS: Impaired awareness of hypoglycaemia (IAH) in type 1 diabetes may develop through a process referred to as habituation. Consistent with this, a single bout of high intensity interval exercise as a novel stress stimulus improves counterregulatory responses (CRR) to next-day hypoglycaemia, referred to as dishabituation. This longitudinal pilot study investigated whether 4 weeks of high intensity interval training (HIIT) has sustained effects on counterregulatory and symptom responses to hypoglycaemia in adults with type 1 diabetes and IAH...
February 2024: Diabetologia
https://read.qxmd.com/read/37960507/evaluation-of-the-traumaguard-balloon-in-balloon-catheter-design-for-intra-abdominal-pressure-monitoring-insights-from-pig-and-human-cadaver-studies
#19
JOURNAL ARTICLE
Salar Tayebi, Tim McKinney, Cynthia McKinney, Dipak Delvadia, Marc-Alan Levine, Edward S Spofford, Luca Malbrain, Johan Stiens, Wojciech Dabrowski, Manu L N G Malbrain
Introduction : Intra-abdominal pressure (IAP) monitoring is crucial for the detection and prevention of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). In the 1970s, air-filled catheters (AFCs) for urodynamic studies were introduced as a solution to overcome the limitations of water-perfused catheters. Recent studies have shown that for correct IAP measurement with traditional AFC, the bladder needs to be primed with 25 mL of saline solution to allow pressure wave transmission to the transducer outside of the body, which limits continuous IAP monitoring...
October 29, 2023: Sensors
https://read.qxmd.com/read/37942482/current-and-future-therapies-to-treat-impaired-awareness-of-hypoglycemia
#20
REVIEW
Erica L Macon, Micah H Devore, Yu Kuei Lin, Megan B Music, Mason Wooten, Colleen A McMullen, Andrea M Woodcox, Ashlee R Marksbury, Zachary Beckner, Bansi V Patel, Lily A Schoeder, Ashley N Iles, Simon J Fisher
In order to achieve optimal glycemic control, intensive insulin regimes are needed for individuals with Type 1 Diabetes (T1D) and insulin-dependent Type 2 Diabetes (T2D). Unfortunately, intensive glycemic control often results in insulin-induced hypoglycemia. Moreover, recurrent episodes of hypoglycemia result in both the loss of the characteristic warning symptoms associated with hypoglycemia and an attenuated counterregulatory hormone responses. The blunting of warning symptoms is known as impaired awareness of hypoglycemia (IAH)...
2023: Frontiers in Pharmacology
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