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https://www.readbyqxmd.com/read/29223965/advancing-prevention-of-sexually-transmitted-infections-through-point-of-care-testing-target-product-profiles-and-landscape-analysis
#1
Igor Toskin, Maurine Murtagh, Rosanna W Peeling, Karel Blondeel, Joanna Cordero, James Kiarie
OBJECTIVES: Advancing the field of point-of-care testing (POCT) for STIs can rapidly and substantially improve STI control and prevention by providing targeted, essential STI services (case detection and screening). POCT enables definitive diagnosis and appropriate treatment in a single visit and home and community-based testing. METHODS: Since 2014, the WHO Department of Reproductive Health and Research, in collaboration with technical partners, has completed four landscape analyses of promising diagnostics for use at or near the point of patient care to detect syphilis, Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis and the human papillomavirus...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29223086/perceived-versus-actual-water-quality-community-studies-in-rural-oaxaca-mexico
#2
Lewis Stetson Rowles, Reinaldo Alcalde, Francisca Bogolasky, Soyoon Kum, Farith A Diaz-Arriaga, Craig Ayres, Anne M Mikelonis, Luis Javier Toledo-Flores, Manuel Gerardo Alonso-Gutiérrez, Maria Eufemia Pérez-Flores, Desmond F Lawler, Peter M Ward, Juana Yolanda Lopez-Cruz, Navid B Saleh
Compromised water quality risks public health, which becomes particularly acute in economically marginalized communities. Although the majority of the clean-water-deprived population resides in Sub-Saharan Africa and Asia, a significant portion (32 million) lives in Meso- and Latin-America. Oaxaca is one of the marginalized southern states of Mexico, which has experienced high morbidity from infectious diseases and also has suffered from a high rate of infant mortality. However, there has been a paucity of reports on the status of water quality of culturally diverse rural Oaxaca...
December 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29222953/bacterial-community-changes-in-copper-and-pex-drinking-water-pipeline-biofilms-under-extra-disinfection-and-magnetic-water-treatment
#3
Jenni Inkinen, Balamuralikrishna Jayaprakash, Merja Ahonen, Tarja Pitkänen, Riika Mäkinen, Anna Pursiainen, Jorge W Santo Domingo, Heidi Salonen, Michael Elk, Minna M Keinänen-Toivola
AIMS: To study stability of biofilms and water quality in pilot scale drinking water copper and PEX pipes in changing conditions (extra disinfection, magnetic water treatment MWT). METHODS AND RESULTS: Next-generation sequencing (NGS) of 16S ribosomal RNA genes (rDNA) to describe total bacterial community and ribosomal RNA (rRNA) to describe active bacterial members in addition to traditional microbiological methods were applied. Biofilms from control copper and PEX pipes shared same most abundant bacteria (Methylobacterium spp...
December 9, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29220341/auditing-safety-of-compounding-and-reconstituting-of-intravenous-medicines-on-hospital-wards-in-finland
#4
Eeva Suvikas-Peltonen, Joni Palmgren, Verner Häggman, Ercan Celikkayalar, Raija Manninen, Marja Airaksinen
On the hospital wards in Finland, nurses generally reconstitute intravenous medicines, such as antibiotics, analgesics, and antiemetics prescribed by doctors. Medicine reconstitution is prone to many errors. Therefore, it is important to identify incorrect practices in the reconstitution of medicine to improve patient safety in hospitals. The aim of this study was to audit the compounding and reconstituting of intravenous medicines on hospital wards in a secondary-care hospital in Finland by using an assessment tool and microbiological testing for identifying issues posing patient safety risks...
November 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/29218304/from-invention-to-innovation-risk-analysis-to-integrate-one-health-technology-in-the-dairy-farm
#5
Andrea Lombardo, Carlo Boselli, Simonetta Amatiste, Simone Ninci, Chiara Frazzoli, Roberto Dragone, Alberto De Rossi, Gerardo Grasso, Alberto Mantovani, Giovanni Brajon
Current Hazard Analysis Critical Control Points (HACCP) approaches mainly fit for food industry, while their application in primary food production is still rudimentary. The European food safety framework calls for science-based support to the primary producers' mandate for legal, scientific, and ethical responsibility in food supply. The multidisciplinary and interdisciplinary project ALERT pivots on the development of the technological invention (BEST platform) and application of its measurable (bio)markers-as well as scientific advances in risk analysis-at strategic points of the milk chain for time and cost-effective early identification of unwanted and/or unexpected events of both microbiological and toxicological nature...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29217934/the-prevalence-of-antibiotic-resistant-diarrhogenic-bacterial-species-in-surface-waters-south-eastern-nigeria
#6
Stanley C Onuoha
Background: This study assessed the bacteriological qualities of surface waters in Afikpo, between April and September 2016. Methods: Surface water samples were collected from three streams for bacteriological analysis. Bacteria species were isolated using standard microbiological and biochemical techniques. Antibiotic susceptibility study was carried out using Kirby Bauer disc diffusion method. Results: The result of the mean heterotrophic bacteria count from the streams showed that Okpu stream had 209...
July 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29216923/supervised-learning-for-infection-risk-inference-using-pathology-data
#7
Bernard Hernandez, Pau Herrero, Timothy Miles Rawson, Luke S P Moore, Benjamin Evans, Christofer Toumazou, Alison H Holmes, Pantelis Georgiou
BACKGROUND: Antimicrobial Resistance is threatening our ability to treat common infectious diseases and overuse of antimicrobials to treat human infections in hospitals is accelerating this process. Clinical Decision Support Systems (CDSSs) have been proven to enhance quality of care by promoting change in prescription practices through antimicrobial selection advice. However, bypassing an initial assessment to determine the existence of an underlying disease that justifies the need of antimicrobial therapy might lead to indiscriminate and often unnecessary prescriptions...
December 8, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29216684/the-impact-of-corynebacterium-glucuronolyticum-on-semen-parameters-a-prospective-pre-post-treatment-study
#8
T Meštrović, B Bedenić, J Wilson, S Ljubin-Sternak, M Sviben, M Neuberg, R Ribić, G Kozina, Z Profozić
Corynebacterium glucuronolyticum (C. glucuronolyticum) is a rare isolate that is only recently being acknowledged as a potential urogenital pathogen. The bibliographical references on this bacterial species are scarce, and its influence on all semen parameters was hitherto unknown - therefore, the aim of this study was to evaluate its effects on a range of sperm quality parameters. A prospective approach to compare semen parameters before and after treatment was used in this study. C. glucuronolyticum in semen specimens was identified using analytical profile index biotyping system (API Coryne) and additionally confirmed by matrix-assisted laser desorption/ionization time-of-flight mass-spectrometry (MALDI-TOF MS), with the determination of antimicrobial susceptibility by Kirby-Bauer method...
December 7, 2017: Andrology
https://www.readbyqxmd.com/read/29215775/an-assessment-of-the-microbiological-quality-and-safety-of-raw-drinking-milk-on-retail-sale-in-england
#9
Caroline Willis, Frieda Jørgensen, Heather Aird, Nicola Elviss, Andrew Fox, Claire Jenkins, Deborah Fenelon, Lorraine Sadler-Reeves, Jim McLauchlin
AIMS: This study aimed to review the microbiological results for raw drinking milk (RDM) samples submitted to Public Health England laboratories between 2014 and 2016 in order to produce up-to-date data on the microbiological safety of RDM and inform future risk assessments on its sale. METHODS AND RESULTS: A total of 902 samples of RDM were collected from retail sale in England for microbiological examination. Overall, 454/770 samples (59.0%) taken for routine monitoring were of a satisfactory quality, whilst eight (1...
December 7, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29208562/microbiological-factors-affecting-clostridium-difficile-recurrence
#10
REVIEW
C H Chilton, D S Pickering, J Freeman
BACKGROUND: Recurrent Clostridium difficile infection (rCDI) places a huge economic and practical burden on healthcare facilities. Furthermore, rCDI may impact quality of life, leaving patients in a 'rCDI cycle', and dependant on antibiotic therapy. AIMS: This article discusses the importance of microbiological factors in the development of rCDI. SOURCES: Literature was drawn from a search of PubMed from 2000 onwards with the search term "recurrent Clostridium difficile infection"; and further references quoted within these articles...
December 2, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29207304/evaluating-statistical-model-performance-in-water-quality-prediction
#11
Rodelyn Avila, Beverley Horn, Elaine Moriarty, Roger Hodson, Elena Moltchanova
Exposure to contaminated water while swimming or boating or participating in other recreational activities can cause gastrointestinal and respiratory disease. It is not uncommon for water bodies to experience rapid fluctuations in water quality, and it is therefore vital to be able to predict them accurately and in time so as to minimise population's exposure to pathogenic organisms. E. coli is commonly used as an indicator to measure water quality in freshwater, and higher counts of E. coli are associated with increased risk to illness...
December 2, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29197785/impact-of-gingivitis-treatment-for-diabetic-patients-on-quality-of-life-related-to-periodontal-objective-parameters-a-randomized-controlled-clinical-trial
#12
Sheila C Cortelli, Fernando O Costa, Antonio Gargioni-Filho, Davi R Aquino, Luis O M Cota, Alexandre P Scherma, Taís B Miranda, Jose R Cortelli
OBJECTIVES: Patients with diabetes have a poor oral health-related quality of life (OHRQoL). It is not clear if this situation could be changed with effective periodontal treatment. This study examined both patients with diabetes and systemically healthy individuals to discover the impact of a gingivitis treatment protocol on OHRQoL and its relation to objective periodontal parameters. DESIGN: After ultrasonic debridement, patients were randomly assigned to an essential-oils (EO) or placebo mouthwash group...
November 30, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29197061/influence-of-technological-and-municipal-wastewaters-on-vulnerable-karst-riverine-system-krka-river-in-croatia
#13
Vlatka Filipović Marijić, Damir Kapetanović, Zrinka Dragun, Damir Valić, Nesrete Krasnići, Zuzana Redžović, Ivana Grgić, Jakov Žunić, Dáša Kružlicová, Peter Nemeček, Dušica Ivanković, Irena Vardić Smrzlić, Marijana Erk
Exceptional natural value of karst rivers, as well as their potential as a source of drinking water supply, contributes to the importance of developing strict environmental protection. Although most of its watercourse is proclaimed national park, Krka River is impacted by technological and municipal wastewaters, which are released without proper purification only 2 km upstream of the park border. In order to assess water ecological status of the Krka River, vulnerability of karst ecosystem and potential threat to the Krka National Park, spatial and temporal variability of physico-chemical and microbiological water parameters, as well as concentrations of 25 total dissolved metals/metalloids were evaluated...
December 2, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29195988/recent-advances-in-microencapsulation-of-natural-sources-of-antimicrobial-compounds-used-in-food-a-review
#14
REVIEW
Javier Castro-Rosas, Carlos Raimundo Ferreira-Grosso, Carlos Alberto Gómez-Aldapa, Esmeralda Rangel-Vargas, María Luisa Rodríguez-Marín, Fabiola Araceli Guzmán-Ortiz, Reyna Nallely Falfan-Cortes
Food safety and microbiological quality are major priorities in the food industry. In recent years, there has been an increasing interest in the use of natural antimicrobials in food products. An ongoing challenge with natural antimicrobials is their degradation during food storage and/or processing, which reduces their antimicrobial activity. This creates the necessity for treatments that maintain their stability and/or activity when applied to food. Microencapsulation of natural antimicrobial compounds is a promising alternative once this technique consists of producing microparticles, which protect the encapsulated active substances...
December 2017: Food Research International
https://www.readbyqxmd.com/read/29192424/interventions-for-old-world-cutaneous-leishmaniasis
#15
REVIEW
Julio Heras-Mosteiro, Begoña Monge-Maillo, Mariona Pinart, Patricia Lopez Pereira, Ludovic Reveiz, Emely Garcia-Carrasco, Pedro Campuzano Cuadrado, Ana Royuela, Irene Mendez Roman, Rogelio López-Vélez
BACKGROUND: Cutaneous leishmaniasis, caused by a parasitic infection, is considered one of the most serious skin diseases in many low- and middle-income countries. Old World cutaneous leishmaniasis (OWCL) is caused by species found in Africa, Asia, the Middle East, the Mediterranean, and India. The most commonly prescribed treatments are antimonials, but other drugs have been used with varying success. As OWCL tends to heal spontaneously, it is necessary to justify the use of systemic and topical treatments...
December 1, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29188037/influence-of-physicochemical-parameters-on-storage-stability-microbiological-quality-of-fresh-unpasteurized-fruit-juices
#16
Phoebe P Kaddumukasa, Samuel M Imathiu, Julius M Mathara, Jesca L Nakavuma
Fresh juices rich in health and nutritional benefits are valued for their fresh flavor, taste, and aroma. These juices' quality however is affected by factors like temperature, light, and microbiological contamination significantly changing physicochemical parameters and storage stability. Physicochemical and microbiological analyses of passion fruit, pineapple, and mango juices in dark and light bottles at 24°C and 4°C were conducted in Kampala, Uganda for 12 days. Physicochemical parameters significantly reduced (p < ...
November 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/29188031/effects-of-different-ozonized-slurry-ice-treatments-and-superchilling-storage-1%C3%A2-c-on-microbial-spoilage-of-two-important-pelagic-fish-species
#17
Gioacchino Bono, Charles Odilichukwu R Okpala, Sergio Vitale, Vincenzo Ferrantelli, Annamaria Di Noto, Antonella Costa, Calogero Di Bella, Daniela Lo Monaco
Combining different preservative treatments for improving quality and safety of fishery products increasingly receives global research attention. Consistent with this pursuit, the current research was undertaken to determine the effects of different ozonized slurry-ice treatments and superchilling (-1°C) storage on microbial spoilage of European anchovy (Eugraulis encrasicolus) and sardine (Sardina pilchardus), which are two commercially important pelagic fish species. After the catch (within <5 hr) and at defined scheduled storage times, ozone has been discharged once on sardine (herein referred to as "One-T") and repeatedly/sequentially on European anchovy (herein referred to as "Seq-T")...
November 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/29187693/-a-simple-and-efficient-rna-extraction-method-from-deep-sea-hydrothermal-vent-chimney-structures
#18
Hisashi Muto, Yoshihiro Takaki, Miho Hirai, Sayaka Mino, Shigeki Sawayama, Ken Takai, Satoshi Nakagawa
RNA-based microbiological analyses, e.g., transcriptome and reverse transcription-quantitative PCR, require a relatively large amount of high quality RNA. RNA-based analyses on microbial communities in deep-sea hydrothermal environments often encounter methodological difficulties with RNA extraction due to the presence of unique minerals in and the low biomass of samples. In the present study, we assessed RNA extraction methods for deep-sea vent chimneys that had complex mineral compositions. Mineral-RNA adsorption experiments were conducted using mock chimney minerals and Escherichia coli total RNA solution, and showed that detectable RNA significantly decreased possibly due to adsorption onto minerals...
November 30, 2017: Microbes and Environments
https://www.readbyqxmd.com/read/29187579/urinary-tract-infection-antibiotic-trial-study-design-a-systematic-review
#19
REVIEW
Romain Basmaci, Konstantinos Vazouras, Julia Bielicki, Laura Folgori, Yingfen Hsia, Theoklis Zaoutis, Mike Sharland
CONTEXT: Urinary tract infections (UTIs) represent common bacterial infections in children. No guidance on the conduct of pediatric febrile UTI clinical trials (CTs) exist. OBJECTIVE: To assess the criteria used for patient selection and the efficacy end points in febrile pediatric UTI CTs. DATA SOURCES: Medline, Embase, Cochrane central databases, and clinicaltrials.gov were searched between January 1, 1990, and November 24, 2016. STUDY SELECTION: We combined Medical Subject Headings terms and free-text terms for "urinary tract infections" and "therapeutics" and "clinical trials" in children (0-18 years), identifying 3086 articles...
November 29, 2017: Pediatrics
https://www.readbyqxmd.com/read/29178485/shelf-life-of-boiled-salted-duck-meat-stored-under-normal-and-modified-atmosphere
#20
Yang Zhai, Jichao Huang, Iftikhar Ali Khan, Yuchen Guo, Ming Huang, Guanghong Zhou
The objective of this study was to investigate the physicochemical properties and changes in the microbial counts of boiled salted duck (BSD) meat packed under various conditions. BSD meat was stored under normal atmosphere (C) and two modified atmosphere packaging (MAP) conditions: M1 (N2 , 100%) and M2 (CO2 /N2 , 30%/70%) at 4 °C. Microbiological quality, pH, redness, lipid oxidation, headspace gas composition, and water activity of BSD meat were measured. The results showed that the time to reach the maximum acceptable total viable counts (TVC, 4...
November 27, 2017: Journal of Food Science
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