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Erik Landfeldt, Anna Castelo-Branco, Axel Svedbom, Emil Löfroth, Andrius Kavaliunas, Jan Hillert
BACKGROUND: Several studies have investigated the impact of multiple sclerosis (MS) on the risk of divorce. However, current evidence is inconclusive and limited by e.g. small sample populations, short follow-up, and/or lack of a control group. The objective of this retrospective, observational study was to estimate the long-term impact of MS on the risk of divorce. METHODS: Swedish patients diagnosed with MS between 1975 and 2012 were identified in a nationwide disease-specific register (the Swedish Multiple Sclerosis Registry) and matched with general population controls based on age, sex, region of residency, and marital status...
July 3, 2018: Multiple Sclerosis and related Disorders
Yvonne Rosalie Elisabeth Skogsdal, Jan Åke Karlsson, Yang Cao, Helena Elisabeth Fadl, Tanja Adele Tydén
INTRODUCTION: Limited attention has been paid to the use of contraception in relation to women's family planning intentions. The aim of this study was to investigate the use of contraception during the most recent intercourse as well as the reproductive intentions of Swedish speaking women requesting contraceptive counseling. MATERIAL AND METHODS: A cross-sectional baseline survey in a randomized controlled trial regarding reproductive life planning (before randomization)...
July 14, 2018: Acta Obstetricia et Gynecologica Scandinavica
Ran Kim, Tae Ki Yoon, Inn Soo Kang, Mi Kyoung Koong, Yoo Shin Kim, Myung Joo Kim, Yubin Lee, Jayeon Kim
PURPOSE: The aim of this study is to analyze women's opinions and their decision making processes regarding elective oocyte cryopreservation (OC). METHODS: One hundred twenty-four women who had elective OC counseling at the CHA Seoul Fertility Center were asked to complete a survey after their first visit. Data collection regarding age, marital status, monthly income, occupation, religion, reproductive history, questions about the participant's view on their own fecundity, and future parenthood were included...
July 13, 2018: Journal of Assisted Reproduction and Genetics
Robert P Nolan, Ross Feldman, Martin Dawes, Janusz Kaczorowski, Hazel Lynn, Susan I Barr, Carolyn MacPhail, Scott Thomas, Jack Goodman, Gunther Eysenbach, Sam Liu, Rika Tanaka, Jelena Surikova
BACKGROUND: The efficacy of internet-based interventions to improve hypertension management is not established. We evaluated the therapeutic benefit of e-counseling by adapting best evidence guidelines for behavioral counseling. METHODS AND RESULTS: This multicenter double-blind randomized controlled trial included assessments at baseline, 4 months, and 12 months. Participants were 35 to 74 years of age and diagnosed with hypertension: systolic/diastolic blood pressure (BP) 130 to 180/85 to 110 mm Hg...
July 2018: Circulation. Cardiovascular Quality and Outcomes
Luc Joyeux, Enrico Danzer, Alan W Flake, Jan Deprest
Spina bifida aperta (SBA) is one of the most common congenital malformations. It can cause severe lifelong physical and neurodevelopmental disabilities. Experimental and clinical studies have shown that the neurological deficits associated with SBA are not simply caused by incomplete neurulation at the level of the lesion. Additional damage is caused by prolonged exposure of the spinal cord and nerves to the intrauterine environment and a suction gradient due to cerebrospinal fluid leakage, leading to progressive downward displacement of the hindbrain...
July 13, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
Lizzy Mm Boots, Marjolein E de Vugt, Gertrudis Ijm Kempen, Frans Rj Verhey
BACKGROUND: The benefits of electronic health support for dementia caregivers are increasingly recognized. Reaching caregivers of people with early-stage dementia could prevent high levels of burden and psychological problems in the later stages. OBJECTIVE: The current study evaluates the effectiveness of the blended care self-management program, Partner in Balance, compared to a control group. METHODS: A single-blind randomized controlled trial with 81 family caregivers of community-dwelling people with mild dementia was conducted...
July 13, 2018: Journal of Medical Internet Research
Mitchell S Howard, Kristen L DiDonato, Daniel L Janovick, Michelle N Schroeder, Mary F Powers, Andrew G Azzi, Aaron J Lengel
OBJECTIVES: To identify athletes' interests in receiving advice about sports supplements from a pharmacist in a supermarket setting and to identify pharmacists' knowledge, confidence, and enthusiasm for providing counseling on various sports supplements. METHODS: Two cross-sectional surveys were developed and administered. One survey was administered to athletes at local northwestern Ohio fitness facilities, and 1 survey was administered to pharmacists in chain pharmacies during mid-February to mid-March 2017...
July 2018: Journal of the American Pharmacists Association: JAPhA
Irene Valenzuela, Maria Segura-Puimedon, Benjamín Rodríguez-Santiago, Paula Fernández-Alvarez, Teresa Vendrell, Lluís Armengol, Eduardo Tizzano
PRMT7 encodes for an arginine methyltransferase that methylates arginine residues on various protein substrates and has been shown to play a role in various developmental processes. Mutations in PRMT7 have been recently shown to be implicated in a phenotype with intellectual disability, short stature and brachydactyly, and considered to be a phenocopy of pseudohypoparathyroidism. We report a patient with short stature, psychomotor delay, hearing loss and brachydactyly, for whom whole exome sequencing detected two mutations in PRMT7 and parental segregation studies detected biallelic mutation inheritance...
July 10, 2018: European Journal of Medical Genetics
Luciana E Hebert, Brandon J Hill, Michael Quinn, Jane L Holl, Amy K Whitaker, Melissa L Gilliam
OBJECTIVE: To evaluate the effect of miPlan, a waiting-room contraceptive counseling mobile application (app), on interest in discussing long-acting reversible contraception (LARC) during the clinical encounter and LARC uptake. STUDY DESIGN: This randomized controlled trial evaluated the miPlan contraceptive counseling app. African American and Latina young women ages 15 to 29years attending four family planning clinics in a large Midwestern city were randomized to either: 1) use miPlan (intervention) prior to the contraceptive clinic visit or 2) contraceptive clinic visit alone (control)...
July 10, 2018: Contraception
Rae Jean Proeschold-Bell, Donna M Evon, Christina Makarushka, John B Wong, Santanu K Datta, Jia Yao, Ashwin A Patkar, Paolo Mannelli, Terra Hodge, Susanna Naggie, Julius M Wilder, Michael W Fried, Donna Niedzwiecki, Andrew J Muir
INTRODUCTION: Among patients with hepatitis C virus (HCV) infection, alcohol synergistically increases the risk of cirrhosis, hepatocellular carcinoma, and death. Randomized controlled trials of integrated models of HCV-alcohol treatment have been recommended but only performed in patients with severe alcohol use disorders. OBJECTIVES: This pragmatic randomized controlled trial seeks to compare clinical effectiveness and cost-effectiveness of integrated alcohol treatment compared to enhanced treatment as usual (TAU) on alcohol consumption and economic outcomes among patients ever infected with HCV...
July 10, 2018: Contemporary Clinical Trials
Dorothee Volkert, Anne Marie Beck, Tommy Cederholm, Alfonso Cruz-Jentoft, Sabine Goisser, Lee Hooper, Eva Kiesswetter, Marcello Maggio, Agathe Raynaud-Simon, Cornel C Sieber, Lubos Sobotka, Dieneke van Asselt, Rainer Wirth, Stephan C Bischoff
BACKGROUND: Malnutrition and dehydration are widespread in older people, and obesity is an increasing problem. In clinical practice, it is often unclear which strategies are suitable and effective in counteracting these key health threats. AIM: To provide evidence-based recommendations for clinical nutrition and hydration in older persons in order to prevent and/or treat malnutrition and dehydration. Further, to address whether weight-reducing interventions are appropriate for overweight or obese older persons...
June 18, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Brigid Dineley, Tejal Patel, Morgan Black, Rob Koziarski, Larkin Lamarche, Dustin Costescu
OBJECTIVE: To examine the utility of a patient-level information video as part of the contraception consultation visit. Specifically, to assess the impact of the video on women's contraception choice, and, further, to assess patient and provider acceptability of incorporating the video into the patient visit. METHODS: A pre-post study design was used to assess the impact on patients' contraceptive choices and knowledge. Participants (n = 49) answered questions regarding contraceptive preferences and knowledge of long-acting reversible contraception (LARC), then watched a 12-minute patient-level counselling video that presented evidence-based information about contraception in descending order of effectiveness...
July 11, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Nicole Pizzorni, Antonio Schindler, Matteo Sozzi, Massimo Corbo, Marco Gilardone
OBJECTIVES: Selecting the appropriate repertoire for an opera singer may be crucial for both the prevention of voice disorders and the career progression. Here, we reviewed the score of 14 Verdi's operas to gain the data for the creation of the vocal score profile of each role. MATERIALS AND METHODS: Seven musicians were involved in the analysis process. Notes were counted and reported as absolute and relative frequency. Pitch measurements included pitch range, percentage of high-pitched notes, percentage of medium-pitched notes, percentage of low-pitched notes, high-pitched and low-pitched notes rate, percentage of the notes in the passaggio, identification of the prevalent octave, percentage of notes in the prevalent octave, and percentage of notes in a moderate range tessitura...
July 10, 2018: Journal of Voice: Official Journal of the Voice Foundation
Christine L Taylor, Clifford J Rosen, Johanna T Dwyer
No abstract text is available yet for this article.
July 10, 2018: Journal of the Academy of Nutrition and Dietetics
Girma Alemayehu Beyene, Lelisa Sena Dadi, Solomon Berhanu Mogas
BACKGROUND: Despite wide spread use of Antiretroviral Therapy (ART) by pregnant women living with Human Immunodeficiency Virus (HIV), the transmission rate is still higher by 18% after breastfeeding ends. The aim of this study was to identify factors affecting mother-to-child HIV transmission. METHODS: Unmatched case-control study was conducted in Addis Ababa, from April to May, 2017. A case was HIV positive mother who had been on PMTCT program with her child confirmed HIV positive at or before 24 months and control was HIV positive mother who had been on PMTCT program with her child tested definitive HIV negative at 24 months...
July 13, 2018: BMC Infectious Diseases
Étienne Bourassa-Moreau, Hubert Labelle, Stefan Parent, Micheal Timothy Hresko, Daniel Sucato, Laurence G Lenke, Michelle Marks, Jean-Marc Mac-Thiong
STUDY DESIGN: Prospective multicenter study of the changes in SRS-22 scores for 78 patients younger than 25 years old surgically treated for lumbosacral spondylolisthesis OBJECTIVE.: Report the change of health-related quality of life (HRQOL) in patients younger than 25 years after surgical treatment of lumbosacral spondylolisthesis. SUMMARY OF BACKGROUND DATA: There is a paucity of data with regard to the influence of surgical treatment on the HRQOL of patients with lumbosacral spondylolisthesis...
July 12, 2018: Spine
Linda M O'Neill, Emer Guinan, Suzanne L Doyle, Annemarie E Bennett, Conor Murphy, Jessie A Elliott, Jacintha OʼSullivan, John V Reynolds, Juliette Hussey
OBJECTIVE: The Rehabilitation Strategies in Esophagogastric cancer (RESTORE) randomized controlled trial evaluated the efficacy of a 12-week multidisciplinary program to increase the cardiorespiratory fitness and health-related quality of life (HRQOL) of esophagogastric cancer survivors. BACKGROUND: Patients following treatment for esophagogastric cancer are at risk of physical deconditioning, nutritional compromise, and sarcopenia. Accordingly, compelling rationale exists to target these impairments in recovery...
July 12, 2018: Annals of Surgery
Azam Raoofi, Effat Hatefnia, Anoshirvan Kazemnejad
Hepatitis B (HB) is one of the major public health problems and a major cause of liver cirrhosis and hepatocellular carcinoma (HCC). The aim of this study was to evaluate the effect of a model-based educational intervention on preventive health behavior of hepatitis B vaccination among women who were going to get married (pending marriage women). Seventy pending marriage women were selected from martial counseling centers. The participants' knowledge, health beliefs model (HBM) constructs, and intention to receive HB vaccination were collected using a questionnaire based on HBM...
July 13, 2018: Social Work in Public Health
Alison T Brenner, Jewels Rhode, Jeff Y Yang, Dana Baker, Rebecca Drechsel, Marcus Plescia, Daniel S Reuland, Tom Wroth, Stephanie B Wheeler
BACKGROUND: Colorectal cancer (CRC) screening is effective but underused. Screening rates are lower among Medicaid beneficiaries versus other insured populations. No studies have examined mailed fecal immunochemical testing (FIT)-based outreach programs for Medicaid beneficiaries. METHODS: In a patient-level randomized controlled trial, a mailed CRC screening reminder plus FIT, sent from an urban health department to Medicaid beneficiaries, was compared with the same reminder without FIT...
July 13, 2018: Cancer
Aleksandra Ratajczak, Karol Ratajczak, Wojciech Feleszko
Environmental tobacco smoke (ETS) exposure is considered an important public health issue in pediatric population. In this study, we aimed to investigate parents' knowledge on side effects of passive smoking and counseling for parental smoking among pediatricians and family practitioners. Participants were biological parents of pediatric patients up to the age of 18 years old who attended Pediatric Hospital of Medical University of Warsaw. The questionnaire included 28 questions and queries on environmental tobacco smoke in children's environment...
July 2, 2018: International Journal of Environmental Research and Public Health
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