keyword
https://read.qxmd.com/read/33775070/effect-of-cereal-products-supplementation-with-american-blueberries-cranberries-and-cinnamon-on-the-formation-of-type-a-and-b-trichothecenes-group
#21
JOURNAL ARTICLE
Piotr Pokrzywa, Ewa Cieślik, Magdalena Surma
INTRODUCTION: Mycotoxins - secondary mould metabolites with undesirable effects for humans - are common in the environment. These toxins are mainly produced by fungi of the genera Penicilium, Aspergillus and Fusarium. OBJECTIVE: The aim of this study was to evaluate the applicability of various sources of antioxidants (blueberries lyophilisate, cranberries lyophilisate and cinnamon powder), at 5 different concentrations (3%, 5%, 10%, 20%, 30%), to inhibit the formation of mycotoxins during the storage of cereal products...
March 18, 2021: Annals of Agricultural and Environmental Medicine: AAEM
https://read.qxmd.com/read/33657979/aflatoxin-m-1-in-brazilian-goat-milk-and-health-risk-assessment
#22
JOURNAL ARTICLE
Clarisse J de Matos, Danieli C Schabo, Yuri M do Nascimento, Josean F Tavares, Edeltrudes de O Lima, Paloma O da Cruz, Evandro Leite de Souza, Marciane Magnani, Hemerson I F Magalhães
Contamination of goat milk with aflatoxin M1 (AFM1 ) is a public health concern. This study investigated filamentous fungi in goat feed and quantified AFM1 in milk samples (n = 108) from goat fed forage and concentrate. Based on the detected AFM1 concentration, risk assessment analyses were performed concerning the Estimated Daily Intake (EDI) for one-year-old children and adults. Filamentous fungi were found in goat feed samples in a range of 3.1 ± 1.9 to 4.2 ± 0.2 log CFU/g. Five genera were identified, to cite Aspergillus, Penicillium, Fusarium, Rhizopus and Acremonium...
2021: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://read.qxmd.com/read/33648181/deoxynivalenol-exposure-assessment-through-a-modelling-approach-of-food-intake-and-biomonitoring-data-a-contribution-to-the-risk-assessment-of-an-enteropathogenic-mycotoxin
#23
JOURNAL ARTICLE
Carla Martins, Duarte Torres, Carla Lopes, Daniela Correia, Ana Goios, Ricardo Assunção, Paula Alvito, Arnau Vidal, Marthe De Boevre, Sarah De Saeger, Carla Nunes
Deoxynivalenol (DON), an enteropathogenic mycotoxin produced by Fusarium species, is usually associated with adverse health outcomes such as gastrointestinal diseases and immunotoxicity. To estimate DON exposure of the Portuguese population at national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering the inputs of the food consumption data generated within the National Food and Physical Activity Survey and the human biomonitoring data used to assess the exposure to DON...
February 2021: Food Research International
https://read.qxmd.com/read/33572636/prevalence-of-aflatoxin-and-fumonisin-producing-fungi-associated-with-cereal-crops-grown-in-zimbabwe-and-their-associated-risks-in-a-climate-change-scenario
#24
JOURNAL ARTICLE
Juliet Akello, Alejandro Ortega-Beltran, Bwalya Katati, Joseph Atehnkeng, Joao Augusto, Chama M Mwila, George Mahuku, David Chikoye, Ranajit Bandyopadhyay
In most sub-Saharan African countries, staple cereal grains harbor many fungi and some produce mycotoxins that negatively impact health and trade. Maize and three small grain cereals (sorghum, pearl millet, and finger millet) produced by smallholder farmers in Zimbabwe during 2016 and 2017 were examined for fungal community structure, and total aflatoxin (AF) and fumonisin (FM) content. A total of 800 maize and 180 small grain samples were collected at harvest and during storage from four agroecological zones...
January 31, 2021: Foods (Basel, Switzerland)
https://read.qxmd.com/read/33563140/disseminated-fusariosis-in-immunocompromised-children-a-case-series-and-review-of-literature
#25
JOURNAL ARTICLE
M P Riojas Hernández, D Cisneros Saldaña, D N Vaquera Aparicio, J I Castillo Bejarano, A H Mascareñas de Los Santos, H Villanueva-Lozano, J Treviño-Rangel Rogelio de, M E De la O Cavazos
In the era of antifungal prophylaxis for cancer patients, Fusarium genus has become the second leading cause of invasive fungal infections and mortality in this group of patients. The intrinsic resistance to antifungal agents and the patient's risk factors are the most important variables for prognosis and survival. Currently, the use of monotherapy in comparison to combined antifungal treatment information is scarce. In this report, we present a series of three cases of children with acute lymphoblastic leukemia and disseminated fusariosis categorized according to the European Organization for Research and Treatment of Cancer/Mycoses Study Group (EORTC/MSG)...
December 2021: Journal of Chemotherapy
https://read.qxmd.com/read/33312641/airborne-fungal-spore-relationships-with-meteorological-parameters-and-skin-prick-test-results-in-elazig-turkey
#26
JOURNAL ARTICLE
Mehmet Kilic, Mustafa Kemal Altunoglu, Gül Esma Akdogan, Salih Akpınar, Erdal Taskın, Ahmet Hamdi Erkal
BACKGROUND: Since fungi spores have high concentrations in the atmosphere during most of the year, they have an important place in respiratory allergies. In this regard, the preparation of calendars showing fungi spore loads for residential areas has much importance in the treatment of the patients. The first aim of this study was to present the airborne fungal spore research results from Eastern Anatolia in Turkey. Then, the mold spores' relationships with the meteorological parameters and skin prick test results were also evaluated...
December 2020: Journal of Environmental Health Science & Engineering
https://read.qxmd.com/read/33050258/systemic-fusariosis-a-rare-complication-in-children-with-acute-lymphoblastic-leukemia
#27
Giada Biddeci, Daniele Donà, Giulia Geranio, Silvia Spadini, Maria Grazia Petris, Marta Pillon, Alessandra Biffi, Maria Caterina Putti
Fusarium species are ubiquitous pathogens causing opportunistic infections in immunocompromised patients. Clinical presentation depends on a host's immunity and can be localized or disseminated. Since there are few reports of disseminated fusariosis in children, we described an unusual case of Fusarium solani infection in a 9-year-old child with acute lymphoblastic leukemia (ALL). This patient presented a deep wound in the elbow at diagnosis. During the induction phase of chemotherapy, he developed multiple skin lesions and severe pneumonia; Fusarium solani was cultured from the skin lesions...
October 9, 2020: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/32535523/mycotoxicological-monitoring-of-breakfast-and-infant-cereals-marketed-in-brazil
#28
JOURNAL ARTICLE
Carlos A Mallmann, Denize Tyska, Carlos A A Almeida, Maurício S Oliveira, Luciane T Gressler
A mycotoxicological survey was conducted in breakfast (n = 172) and infant (n = 43) cereals commercialized in Brazil. Samples were collected in 2018 for analyses of: aflatoxins (AFs) B1 (AFB1 ), B2 , G1 and G2 ; fumonisins (FBs) B1 (FB1 ) and B2 ; zearalenone (ZEN); the trichothecenes (TRCs) deoxynivalenol (DON), T-2 toxin, HT-2 toxin, nivalenol, fusarenon X, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol and diacetoxyscirpenol; and ochratoxin A. FB1 was the most prevalent metabolite in breakfast cereals, being detected in 26...
October 16, 2020: International Journal of Food Microbiology
https://read.qxmd.com/read/32293993/fvstua-is-a-key-regulator-of-sporulation-toxin-synthesis-and-virulence-in-fusarium-verticillioides
#29
JOURNAL ARTICLE
M Rath, N J Crenshaw, L W Lofton, A E Glenn, S E Gold
Fusarium verticillioides is one of the most important pathogens of maize, causing rot and producing fumonisin mycotoxins during infection. Ingestion of fumonisin-contaminated corn causes underperformance and even fatal toxicity in livestock and is associated with neural tube birth defects, growth stunting in children, and some cancers. StuA, an APSES-class transcription factor, is a major developmental transcriptional regulator in fungi. It has been shown to regulate crucial developmental processes, such as sporulation, virulence, and mycotoxin synthesis among others...
July 2020: Molecular Plant-microbe Interactions: MPMI
https://read.qxmd.com/read/31349679/determination-of-deoxynivalenol-biomarkers-in-italian-urine-samples
#30
JOURNAL ARTICLE
Barbara De Santis, Francesca Debegnach, Brunella Miano, Giorgio Moretti, Elisa Sonego, Antonio Chiaretti, Danilo Buonsenso, Carlo Brera
Deoxynivalenol (DON) is a mycotoxin mainly produced by Fusarium graminearum that can contaminate cereals and cereal-based foodstuff. Urinary DON levels can be used as biomarker for exposure assessment purposes. This study assessed urinary DON concentrations in Italian volunteers recruited by age group, namely children, adolescents, adults, and the elderly. In addition, vulnerable groups, namely vegetarians and pregnant women, were included in the study. To determine the urinary DON, its glucuronide and de-epoxydated (DOM-1) forms, an indirect analytical approach was used, measuring free DON and total DON (as sum of free and glucuronides forms), before and after enzymatic treatment, respectively...
July 25, 2019: Toxins
https://read.qxmd.com/read/31272853/children-s-public-health-danger-of-exposure-to-pathogenic-fungi-in-recreational-places-in-the-middle-west-region-of-brazil
#31
JOURNAL ARTICLE
Ronaldo S Pereira, Hugo D Hoffman Dos Santos, Otacília S Moraes, Diniz P Leite Júnior, Rosane C Hahn
BACKGROUND: Dermatophytes are keratinophilic fungi, considered etiological agents of cutaneous mycoses in man and animals. The objective of this work was to isolate dermatophytic and non-dermatophytic fungi in recreational sandboxes (rainy and dry periods) in public day-care centers located in the city of Cuiabá-MT (Middle-west of Brazil). METHODS: Samples (n=200) were collected from the superficial layer of the sandboxes at a depth of 2-5cm in 10 public nurseries in Cuiabá-MT...
July 2, 2019: Journal of Infection and Public Health
https://read.qxmd.com/read/30837741/exposure-assessment-of-infants-and-young-children-on-selected-fusarium-toxins
#32
JOURNAL ARTICLE
Jacek Postupolski, Andrzej Starski, Ewa Ledzion, Joanna Kurpińska-Jaworska, Małgorzata Szczęsna
Background: Mycotoxins belong to substances harmful to human health. They are found mainly in cereal products and their preparations. In particular, infants and young children who consume cereal products, including porridge and gruel, are exposed to these substances. Objective: The aim of the study is to assess the exposure of infants and young children in Poland to micotoxins (ochratoxin A. deoxynivalenol, nivalenol, fumonisins B1 and B1, T-2 and HT-2 toxins) derived from cereal products intended for infants and children...
2019: Roczniki Państwowego Zakładu Higieny
https://read.qxmd.com/read/30821509/validation-of-urinary-sphingolipid-metabolites-as-biomarker-of-effect-for-fumonisins-exposure-in-kenyan-children
#33
JOURNAL ARTICLE
Ruth Nabwire Wangia, David Peter Githanga, Kathy Siyu Xue, Lili Tang, Omu Aggrey Anzala, Jia-Sheng Wang
CONTEXT: Fumonisins [FNs], a group of mycotoxins produced mainly by Fusarium species, are ubiquitous food contaminants, especially for maize. Fumonisin B1 [FB1 ] caused severe toxicities in farm animals, induced kidney and liver tumors in rodents and is associated with many human adverse health effects, including esophageal cancer. International Agency for Research on Cancer [IARC] categorizes FB1 as possible human carcinogen [Group 2B]. Inhibition of ceramide synthesis and disruption of sphingolipids metabolism are well studied as the major mechanisms of FB1 -induced toxicity...
March 1, 2019: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://read.qxmd.com/read/30795513/biological-composition-of-respirable-particulate-matter-in-an-industrial-vicinity-in-south-africa
#34
JOURNAL ARTICLE
Oyewale Mayowa Morakinyo, Matlou Ingrid Mokgobu, Murembiwa Stanley Mukhola, Tshifhiwa Godobedzha
There is a growing concern that exposure to particulate matter of aerodynamic diameter of less than 2.5 µm (PM2.5 ) with biological composition (bioaerosols) may play a key role in the prevalence of adverse health outcomes in humans. This study determined the bacterial and fungal concentrations in PM2.5 and their inhalation health risks in an industrial vicinity in South Africa. Samples of PM2.5 collected on a 47-mm glass fiber filter during winter and summer months were analysed for bacterial and fungal content using standard methods...
February 21, 2019: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/30761910/global-occurrence-of-deoxynivalenol-in-food-commodities-and-exposure-risk-assessment-in-humans-in-the-last-decade-a-survey
#35
JOURNAL ARTICLE
Sakshi Mishra, Sonal Srivastava, Jayant Dewangan, Aman Divakar, Srikanta Kumar Rath
Preventing food from fungal infestation has become a cause of great concern as food safety is of particular importance to public health globally. Recently International Agency for Research on Cancer (IARC) and the World Health Organization (WHO) in its 2016 press release has urged to take action against widespread mycotoxin contamination in developing countries. Deoxynivalenol (DON) is a group B trichothecene mycotoxin, produced by common field pathogens such as Fusarium graminearum and Fusarium culmorum, and reported to be the predominant contaminant of food commodities...
February 14, 2019: Critical Reviews in Food Science and Nutrition
https://read.qxmd.com/read/29601109/fungal-diseases-in-children-and-adolescents-in-a-referral-centre-in-bogota-colombia
#36
JOURNAL ARTICLE
Zulma Alvarado, Claudia Pereira
A cross-sectional descriptive study was conducted at a dermatology referral centre in Bogotá, to estimate the frequencies and aetiologies of mycoses in the population under 18 years of age attending the medical mycology laboratory over a 13-year period (2000-2012). A total of 1337 samples from 1221 patients were evaluated, involving direct examination and culture for 1279 samples, direct examination alone for 50 and culture alone for 8. During the study period, dermatophytosis was diagnosed via culture in 537 cases (40...
August 2018: Mycoses
https://read.qxmd.com/read/29564632/infections-caused-by-fusarium-species-in-pediatric-cancer-patients-and-review-of-published-literature
#37
REVIEW
Mariana Volpe Arnoni, Claudete Rodrigues Paula, Marcos Ereno Auler, Cirilo Cesar Naozuka Simões, Shirley Nakano, Maria Walderez Szeszs, Márcia de Souza Carvalho Melhem, Virgínia Bodelão Richini Pereira, Hans Garcia Garces, Eduardo Bagagli, Eriques Gonçalves Silva, Melissa Ferreira de Macêdo, Luciana da Silva Ruiz
Fusarium species have emerged as responsible for a broad spectrum of infections, including superficial, locally invasive and disseminated ones, especially in the hospital environment. Since there are few reports of invasive and disseminated fusariosis in children, the aim of this study was to report four cases of nosocomial infection caused by this microorganism in children with cancer hospitalized in a public children's hospital located in Brazil. Two of these patients were female and two were male. All patients presented febrile neutropenia, while three patients had acute lymphocytic leukemia and one patient had Wilms' tumor as underlying disease...
December 2018: Mycopathologia
https://read.qxmd.com/read/29360781/assessment-of-urinary-deoxynivalenol-biomarkers-in-uk-children-and-adolescents
#38
JOURNAL ARTICLE
Maria Papageorgiou, Liz Wells, Courtney Williams, Kay White, Barbara De Santis, Yunru Liu, Francesca Debegnach, Brunella Miano, Giorgio Moretti, Stephanie Greetham, Carlo Brera, Stephen L Atkin, Laura J Hardie, Thozhukat Sathyapalan
Deoxynivalenol (DON), the mycotoxin produced mainly by Fusarium graminearum and found in contaminated cereal-based foodstuff, has been consistently detected in body fluids in adults. Available data in children and adolescents are scarce. This study assessed urinary DON concentrations in children aged 3-9 years ( n = 40) and adolescents aged 10-17 years ( n = 39) in the UK. Morning urine samples were collected over two consecutive days and analysed for free DON (un-metabolised form), DON-glucuronides (DON-GlcA), deepoxy deoxynivalenol (DOM-1), and total DON (sum of free DON, DON-GlcA, and DOM-1)...
January 23, 2018: Toxins
https://read.qxmd.com/read/28912948/outbreak-of-fusarium-oxysporum-infections-in-children-with-cancer-an-experience-with-7-episodes-of-catheter-related-fungemia
#39
JOURNAL ARTICLE
Fabianne Carlesse, Anna-Paula C Amaral, Sarah S Gonçalves, Hemilio Xafranski, Maria-Lucia M Lee, Victor Zecchin, Antonio S Petrilli, Abdullah M Al-Hatmi, Ferry Hagen, Jacques F Meis, Arnaldo L Colombo
BACKGROUND: Fusarium species are widely spread in nature as plant pathogens but are also able to cause opportunistic fungal infections in humans. We report a cluster of Fusarium oxysporum bloodstream infections in a single pediatric cancer center. METHODS: All clinical and epidemiological data related to an outbreak involving seven cases of fungemia by Fusarium oxysporum during October 2013 and February 2014 were analysed. All cultured isolates ( n  = 14) were identified to species level by sequencing of the TEF1 and RPB2 genes...
2017: Antimicrobial Resistance and Infection Control
https://read.qxmd.com/read/28380344/mycotoxin-risk-assessment-for-consumers-of-groundnut-in-domestic-markets-in-nigeria
#40
JOURNAL ARTICLE
Oluwawapelumi A Oyedele, Chibundu N Ezekiel, Michael Sulyok, Modupeade C Adetunji, Benedikt Warth, Olusegun O Atanda, Rudolf Krska
The fungal and multi-mycotoxin profiles of groundnuts sold in domestic markets in Nigeria as well as the associated risk to consumers were assessed in the present study. Four hundred fungal isolates representing mainly Aspergillus [58.6%: Aspergillus section Flavi (37.1%) and A. niger-clade (21.5%)], Penicillium (40.9%) and Fusarium (0.5%) were isolated from 82 (97.6%, n=84) groundnut samples collected from four agro-ecological zones (AEZs) of Nigeria. The incidence of aflatoxin-producing A. flavus isolates (71%) was significantly (p<0...
June 19, 2017: International Journal of Food Microbiology
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