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Two midnight

Brad Wright, Xuan Zhang, Momotazur Rahman, Keith Kocher
STUDY OBJECTIVE: Outpatient observation stays are increasingly substituting for standard inpatient hospitalizations. In 2013, the Centers for Medicare & Medicaid Services adopted the controversial Two-Midnight Rule policy to curb long observation stays and better define the use of hospital-based observation services versus inpatient hospitalizations. We seek to determine the extent to which Medicare beneficiaries exposed to long observation stays (>48 hours) are clinically similar to those with short observation stays (≤48 hours) because this has relevance to the Two-Midnight Rule...
March 9, 2018: Annals of Emergency Medicine
Yee-Hsin Kao, Yao-Ting Liu, Malcolm Koo, Jui-Kun Chiang
BACKGROUND: For patients receiving palliative home care, the need to visit the emergency department is considered to be an indicator of poor quality care. The situation can be particularly distressing when it occurs outside of normal hours of palliative home care service. The aim of this study was to investigate the factors for emergency department use during out-of-hours periods of palliative home care service among advanced cancer patients in Taiwan. METHODS: This case-control study was based on a retrospective medical chart review (January 2010 to December 2012) of advanced cancer patients who were receiving palliative home care in a community hospital in south Taiwan...
March 12, 2018: BMC Palliative Care
Steffie H A Brouns, Joyce J Wachelder, Femke S Jonkers, Suze L Lambooij, Jeanne P Dieleman, Harm R Haak
BACKGROUND: Studies investigating different medical conditions and settings have demonstrated mixed results regarding the weekend effect. However, data on the outcome of elderly patients hospitalised on weekends is scarce. The objective was to compare in-hospital and two-day mortality rates between elderly emergency department (ED) patients (≥65 years) admitted on weekends versus weekdays. METHODS: A retrospective cohort study of emergency department visits of internal medicine patients ≥65 years presenting to the emergency department between 01 and 09-2010 and 31-08-2012 was conducted...
March 7, 2018: BMC Emergency Medicine
Nguyen Hong Phuc, Nguyen Thi Kim Oanh
The levels of BTEX (benzene, toluene, ethylbenzene and xylenes) in a congested urban area of Hanoi were characterized in a winter and a transitional period in 2015. Monitoring was conducted at two roads simultaneously with traffic flows and one ambient site together with meteorology. Hourly and bi-hourly BTEX samples collected using charcoal tubes were analyzed by GC-FID. BTEX levels in winter, 131 ± 71 μg/m3 in heavy traffic Truong Chinh (TC) road, 101 ± 29 μg/m3 in small residential Nguyen Ngoc Nai (NN) road, and 30 ± 15 μg/m3 in the ambient air site (AA, about 150 m from each road) were 1...
January 29, 2018: Science of the Total Environment
Hiroshi Yamaguchi, Hiroaki Nagase, Yusuke Ishida, Daisaku Toyoshima, Azusa Maruyama, Kazumi Tomioka, Tsukasa Tanaka, Masahiro Nishiyama, Kyoko Fujita, Taniguchi-Ikeda Mariko, Kandai Nozu, Ichiro Morioka, Noriyuki Nishimura, Hiroshi Kurosawa, Satoshi Takada, Yoshiyuki Uetani, Kazumoto Iijima
Several studies describing the diurnal occurrence of febrile seizures have reported greater seizure frequency early or late in the evening relative to midnight or early morning. However, no articles have reported on the diurnal occurrence of complex febrile seizure. Moreover, no studies have addressed the relationship between seizure severity and diurnal occurrence. We retrospectively evaluated complex febrile seizures in 462 children needing hospitalization, and investigated the relationship between severity and diurnal occurrence according to four categorized time periods (morning, afternoon, evening, and night)...
February 5, 2018: Epilepsy & Behavior: E&B
Shuang Wu, Jie Chen, Chen Li, Delei Kong, Kai Yu, Shuwei Liu, Jianwen Zou
Agricultural nitrate leaching and runoff incurs high nitrogen loads in agricultural irrigation watersheds, constituting one of important sources of atmospheric nitrous oxide (N2O). Two independent sampling campaigns of N2O flux measurement over diel cycles and N2O flux measurements once a week over annual cycles were carried out in an agricultural irrigation watershed in southeast China using floating chamber (chamber-based) and gas transfer equation (model-based) methods. The diel and seasonal patterns of N2O fluxes did not differ between the two measurement methods...
February 7, 2018: Environmental Monitoring and Assessment
Kare P Mahmud, Bruno P Holzapfel, Yann Guisard, Jason P Smith, Sharon Nielsen, Suzy Y Rogiers
Some plant species demonstrate a pronounced 24 h rhythm in fine root growth but the endogenous and exogenous factors that regulate these diel cycles are unclear. Photoperiod and temperature are known to interact with diel patterns in shoot growth but it is uncertain how these environmental factors are interrelated with below-ground growth. In this particular study, the fine root system of two grapevine species was monitored over a period of ten days with a high resolution scanner, under constant soil moisture and three different photoperiod regimes...
February 1, 2018: Journal of Plant Physiology
Brandyce St Laurent, Supratman Sukowati, Timothy A Burton, David Bretz, Mulyadi Zio, Syah Firman, Sumardi, Heru Sudibyo, Amalia Safitri, Suwito, Puji B Asih, Sully Kosasih, Shinta, William A Hawley, Thomas R Burkot, Frank H Collins, Din Syafruddin, Neil F Lobo
BACKGROUND: The effectiveness of vector control efforts can vary based on the interventions used and local mosquito behaviour and adaptability. In many settings, biting patterns of Anopheles mosquitoes can shift in response to interventions targeting indoor-biting mosquitoes, often resulting in higher proportions of mosquitoes feeding outside or at times when people are not protected. These behaviourally resistant mosquitoes have been shown to sustain residual malaria transmission and limit control efforts...
January 8, 2018: Malaria Journal
Sebastiaan W F Meenderink, Patricia M Quiñones, Peter M Narins
Males of the coqui treefrog, Eleutherodactylus coqui, produce a distinct two-note 'co-qui' advertisement call from sunset to midnight throughout most of the year. Previous work established that both the spectrotemporal aspects of the call and the frequency of highest inner-ear sensitivity change with altitude above sea level. These variations are such that the frequency of the emitted co-note closely matches the frequency to which the inner ear is most sensitive. Given this parallel variation, we expected that the call-evoked behavioural response of male coqui treefrogs would also show an altitude dependence, and hypothesized that males would produce their most robust acoustical territorial response to advertisement calls that match calls from their own altitude...
December 2017: Biology Letters
Jing Gao, Yan Ye, Chenxi Wu, Dingxi Bai, Xiaolin Hou, Jianxia Lv, Yuping Xiang, Xia Zhao
OBJECTIVE: To compare the clinical efficacy differences between acupoint plaster therapy with midnight-noon ebb-flow hour-prescription method and traditional acupoint plaster therapy for senile osteoporosis (SOP). METHODS: With randomized controlled blind design, 76 SOP patients with deficiency of liver and kidney syndrome were randomly divided into an observation group and a control group, 38 cases in each one. Based on oral administration of caltrate D, the patients in the observation group were treated with acupoint plaster therapy with midnight-noon ebb-flow hour-prescription method at Yingu (KI 10), Taixi (KI 3), Dazhong (KI 4), Fuliu (KI 7) and Zhiyin (BL 67), while the patients in the control group were treated with traditional acupoint plaster therapy...
April 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Armando L Morera-Fumero, Estefanía Díaz-Mesa, Pedro Abreu-Gonzalez, Lourdes Fernandez-Lopez, Fernando Guillen-Pino
Free radicals and an oxidant/antioxidant imbalance have been involved in the schizophrenia pathophysiology. The total antioxidant capacity (TAC) is a measure of the antioxidant capacity of a system. Day/night changes are a biological characteristic of hormones such as melatonin or cortisol. There is little information about TAC day/night changes in schizophrenia patients. The aim of this research is to study if there are day/night changes in serum TAC levels of schizophrenia patients. Thirty-two DSM-IV schizophrenia paranoid patients were studied...
2017: PloS One
Özge Telci Çaklılı, Banu İşbilen, Gülcan Yavuz, Selcan Tülü, Banu Mesçi, Aytekin Oğuz
Background/aim: Leptin, ghrelin, and glucagon-like peptide-1 (GLP-1) affect hunger, satiety feelings, and food intake. We hypothesized that during Ramadan, if the brain knows that the body will be hungry until sunset, there may be differences between leptin, ghrelin, and GLP-1 levels in Ramadan and non-Ramadan fasting. Materials and methods: This study had two phases. In the first phase, the participants were asked to skip the dawn meal of Ramadan (suhur), so that 12 h of fasting could be achieved. Participants ceased food intake at midnight, and at noon blood was drawn...
August 23, 2017: Turkish Journal of Medical Sciences
Jocelyn G Millar, Robert F Mitchell, Linnea R Meier, Todd D Johnson, Judith A Mongold-Diers, Lawrence M Hanks
An increasing body of evidence suggests that the volatile pheromones of cerambycid beetles are much more diverse in structure than previously hypothesized. Here, we describe the identification, synthesis, and field testing of (2E,6Z,9Z)-2,6,9-pentadecatrienal as a male-produced aggregation-sex pheromone of the cerambycid Elaphidion mucronatum (Say) (subfamily Cerambycinae, tribe Elaphidiini). This novel structure is unlike any previously described cerambycid pheromone, and in field bioassays attracted only this species...
December 2017: Journal of Chemical Ecology
Shunsuke Nagashima, Madoka Osawa, Hiroto Matsuyama, Wataru Ohoka, Aemi Ahn, Tomoko Wakamura
The guidelines for night and shift workers recommend that after night work, they should sleep in a dark environment during the daytime. However, staying in a dark environment during the daytime reduces nocturnal melatonin secretion and delays its onset. Daytime bright-light exposure after night work is important for melatonin synthesis the subsequent night and for maintaining the circadian rhythms. However, it is not clear whether daytime sleeping after night work should be in a dim- or a bright-light environment for maintaining melatonin secretion...
February 2018: Chronobiology International
Puneet Misra, Anindo Majumdar, Mahesh Chandra Misra, Shashi Kant, Sanjeev Kumar Gupta, Amit Gupta, Subodh Kumar
Background and Aims: There is paucity of data regarding some of the lesser known contextual and epidemiological factors with respect to road traffic injuries (RTIs). The objective was to study the epidemiological profile of RTI victims attending an emergency department of a tertiary care trauma center. Methods: The present study was a hospital-based cross-sectional study conducted in the emergency department of a tertiary care trauma center in New Delhi. All patients of RTI attending the emergency department during the designated data collection days were included in the study...
October 2017: Indian Journal of Critical Care Medicine
Pamela S Noack, Jhanna A Moore, Michael Poon
OBJECTIVE: To evaluate medical costs of novel therapies in complex medical settings using registry data. DATA SOURCE/STUDY SETTING: Primary data, from 2008 to 2010. We used patient registry data to evaluate cost and quality performance of coronary computed tomography angiography (CCTA) in triaging chest pain patients in our tertiary care emergency department and to model financial performance under Medicare's two midnight rule. STUDY DESIGN: Using generalized linear modeling, we retrospectively compared estimated expenditures for evaluation of low-to-intermediate-risk chest pain for demographic and medically risk matched samples of 894 patients each, triaged with CCTA or local standard of care (SOC) using Medicare reimbursement as a proxy...
November 13, 2017: Health Services Research
Zain A Al-Safi, Alex Polotsky, Justin Chosich, Lauren Roth, Amanda A Allshouse, Andrew P Bradford, Nanette Santoro
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis may play a role in the pathogenesis of comorbidities encountered in obesity, including the relative hypogonadotropic hypogonadism that we and others have observed. We sought to examine serum cortisol profiles throughout the day and evening in a sample of normal weight women and women with obesity. In this cross-sectional study, regularly cycling obese (n = 12) and normal weight (n = 10) women were recruited. Mean serum cortisol was measured by frequent blood sampling for 16 h (8am-midnight) in the luteal phase of the menstrual cycle...
October 25, 2017: Gynecological Endocrinology
I Azzam, S Gilad, R Limor, N Stern, Y Greenman
Ghrelin plasma concentration increases in parallel to cortisol after a standardized psychological stress in humans, but the physiological basis of this interaction is unknown. We aimed to elucidate this question by studying the ghrelin response to pharmacological manipulation of the hypothalamic-pituitary-adrenal (HPA) axis. Six lean, healthy male volunteers were examined under four experimental conditions. Blood samples were collected every 30 min for two sequential periods of two hours. Initially, a baseline period was followed by intravenous injection of a synthetic analog of ACTH (250 μg)...
November 2017: Endocrine Connections
Catia Balducci, Angelo Cecinato, Valerio Paolini, Ettore Guerriero, Mattia Perilli, Paola Romagnoli, Carmela Tortorella, Renato Michele Nacci, Aldo Giove, Antonio Febo
The artifacts induced by oxidative degradation and volatilization were assessed with regards to determination of particulate atmospheric PAHs collected at low volume conditions (2.3 m(3) h(-1)) according to the EU Reference Method EN 12341:2014. In order to evaluate the oxidative degradation, PAH measures carried out through collecting airborne particulate with and without ozone denuders were examined. Simultaneously, the influence of volatilization was investigated by comparing concentrations of PAHs in particulate samples collected over 24-h and 12-h using conventional instruments...
September 15, 2017: Chemosphere
Priyadarshini Mishra, Alok Pratap Singh, Vikas Kanaujia, Rachna Agarwal, Prabhaker Mishra, Ashwani Guleria, Alka Tripathi
PURPOSE: The purpose of this study is to measure intraocular pressure (IOP) and evaluate the correlation between IOP and midnight plasma cortisol (MPC) level in patients with Cushing's disease (CD) and other endogenous Cushing's syndrome (ECS). METHODS: This is a cross-sectional study from a single center including newly diagnosed patients with CD or ECS. All patients underwent detailed ophthalmological evaluation. IOP was measured by Goldmann applanation tonometry in the morning and evening on two consecutive days...
September 2017: Indian Journal of Ophthalmology
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