Floris Huider, Yuri Milaneschi, Jouke-Jan Hottenga, Mariska Bot, M Liset Rietman, Almar A L Kok, Tessel E Galesloot, Leen M 't Hart, Femke Rutters, Marieke T Blom, Didi Rhebergen, Marjolein Visser, Ingeborg Brouwer, Edith Feskens, Catharina A Hartman, Albertine J Oldehinkel, Eco J C de Geus, Lambertus A Kiemeney, Martijn Huisman, H Susan J Picavet, W M Monique Verschuren, Hanna M van Loo, Brenda W J H Penninx, Dorret I Boomsma
In this cohort profile article we describe the lifetime major depressive disorder (MDD) database that has been established as part of the BIObanks Netherlands Internet Collaboration (BIONIC). Across the Netherlands we collected data on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition ( DSM-5 ) lifetime MDD diagnosis in 132,850 Dutch individuals. Currently, N = 66,684 of these also have genomewide single nucleotide polymorphism (SNP) data. We initiated this project because the complex genetic basis of MDD requires large population-wide studies with uniform in-depth phenotyping...
March 18, 2024: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies