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https://www.readbyqxmd.com/read/29331010/implants-for-extracapsular-neck-of-femur-fracture-dynamic-hip-screw-versus-intramedullary-nailing
#1
Faisal Farooq Butt, Adnan Shabbair Hussain, Ahmed Mushtaq Khan, Maria Sultan
Neck of femur fractures are the most prevalent type of injury in elderly trauma patients. Both intra and extra capsular type of fractures are equally distributed in the given population. Traditionally, Extra capsular fractures are fixed with Dynamic Hip screw or Intra medullary nailing based on the type of fracture. NICE (National Institute of Clinical Excellence) recommends fixing 31-A1 and 31-A2 fractures with DHS (Dynamic Hip Screw) whereas AO recommends fixing 31-A1 with DHS and 31-A2.1 subtype with DHS and 31-A2...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29329430/increases-in-igf-1-after-anti-tnf-%C3%AE-therapy-are-associated-with-bone-and-muscle-accrual-in-pediatric-crohn-s-disease
#2
Mark D DeBoer, Arthur M Lee, Kirabo Herbert, Jin Long, Meena Thayu, Lindsay M Griffin, Robert N Baldassano, Lee A Denson, Babette S Zemel, Michelle R Denburg, Rita Herskovitz, Mary B Leonard
Context: Low levels of IGF-1 in pediatric and adolescent Crohn's Disease (CD) likely contribute to bone and muscle deficits. Objective: Assess changes in IGF-1 levels and associations with bone and muscle accrual following initiation of anti-TNF-α therapy in pediatric and adolescent CD. Design and Participants: Participants (n=75, age 5-21 years) with CD were enrolled in a prospective cohort study; 63 completed the 12-month visit. Main Outcome Measures: IGF-1 levels at baseline and 10 weeks, and DXA and tibia peripheral quantitative-CT (pQCT) measures of bone and muscle at baseline and 12 months after initiation of anti-TNF-α therapy...
January 10, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29327327/identifying-potentially-common-genes-between-dyslipidemia-and-osteoporosis-using-novel-analytical-approaches
#3
Xu Lin, Cheng Peng, Jonathan Greenbaum, Zhang-Fang Li, Ke-Hao Wu, Zeng-Xin Ao, Tong Zhang, Jie Shen, Hong-Wen Deng
Dyslipidemia (DL) is closely related to osteoporosis (OP), while the exact common genetic mechanisms are still largely unknown. We proposed to use novel genetic analysis methods with pleiotropic information to identify potentially novel and/or common genes for the potential shared pathogenesis associated with OP and/or DL. We assessed the pleiotropy between plasma lipid (PL) and femoral neck bone mineral density (FNK BMD). We jointly applied the conditional false discovery rate (cFDR) method and the genetic analysis incorporating pleiotropy and annotation (GPA) method to the summary statistics provided by genome-wide association studies (GWASs) of FNK BMD (n = 49,988) and PL (n = 188,577) to identify potentially novel and/or common genes for BMD/PL...
January 11, 2018: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/29327108/computed-tomography-for-occult-fractures-of-the-proximal-femur-pelvis-and-sacrum-in-clinical-practice-single-institution-dual-site-experience
#4
Jacob C Mandell, Michael J Weaver, Bharti Khurana
PURPOSE: The purpose of this study was to evaluate the diagnostic performance of CT for assessment of occult fractures of the proximal femur, pelvis, and sacrum. MATERIALS AND METHODS: A retrospective review was performed on patients who received a CT of the hip or pelvis for suspected occult fracture after negative or equivocal radiographs performed within 24 h. The official radiology report was utilized for the determination of CT findings and calculation of sensitivity and specificity...
January 11, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29323746/the-acetabular-and-spino-pelvic-morphologies-are-different-in-subjects-with-symptomatic-cam-femoro-acetabular-impingement
#5
George Grammatopoulos, Andrew D Speirs, K C Geoffrey Ng, Charles Riviere, Kawan S Rakhra, Mario Lamontagne, Paul E Beaule
Acetabular and spino-pelvic (SP) morphological parameters are important determinants of hip joint dynamics. This prospective study aimed to determine whether acetabular and SP morphological differences exist between hips with and without cam morphology and between symptomatic and asymptomatic hips with cam morphology. A cohort of 67 patients/hips was studied. Hips were either asymptomatic with no cam (Controls, n = 18), symptomatic with cam (n = 26) or asymptomatic with cam (n = 23). CT-based quantitative assessments of femoral, acetabular, pelvic and spino-pelvic parameters were performed...
January 11, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29322292/bilateral-symmetrical-comparison-of-the-proximal-femur-using-3d-ct-models
#6
Filip C Dolatowski, Max J Temmesfeld, Claude Pierre-Jerome, Arne Borthne, Sigurd Erik Hoelsbrekken
PURPOSE: Superimposed three-dimensional (3D)-models obtained from CT-images have been used to evaluate displacement of femoral neck fractures, but this method assumes symmetrical anatomy of normal femurs. The present study aimed to compare the spatial orientation of the left and right proximal femur, thus establishing if 3D models can be used as a reference standard for the evaluation of fracture displacement. METHODS: We generated 3D-CT-models of 20 patients with no skeletal pathology of the proximal femurs...
January 10, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29321813/novel-concept-of-a-modular-hip-implant-could-contribute-to-less-implant-failure-in-tha-a-hypothesis
#7
Ronny Grunert, Stefan Schleifenbaum, Robert Möbius, Michael Kopper, Christian Rotsch, Welf-Guntram Drossel, Niels Hammer, Torsten Prietzel
Background: The modularity in total hip arthroplasty (THA) allows orthopaedic surgeons for an exact reconstruction of hip biomechanical parameters especially in revision and tumor arthroplasty. Modular structured femoral stems using taper junctions showed increased implant breakage in the recent past. Presentation of the hypothesis: We hypothesize that a novel modular stem-neck-interface leads to less implant breakage compared to conventional femoral stems. Testing of the hypothesis: For this purpose, a novel modular femoral stem for THA was to design and manufacture...
2018: Patient Safety in Surgery
https://www.readbyqxmd.com/read/29320924/a-model-to-evaluate-pauwels-type-iii-femoral-neck-fractures
#8
Kevin M Magone, Jonas K Owen, Bernard P Kemker, Oliver Bloom, Sidney Martin, Patrick Atkinson
While many femoral neck fractures can be reliably treated with surgical intervention, Pauwels III femoral neck fractures in the young adult population continue to be a challenging injury, and there is no consensus on optimal treatment. As such, there are past and ongoing biomechanical studies to evaluate the fixation provided by different constructs for this inherently unstable fracture. While many investigations rely on cadavers to evaluate the biomechanical performance of a construct, significant inter-subject variability can confound the analysis...
January 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29319657/sciatic-nerve-entanglement-around-a-femoral-prosthesis-during-closed-reduction-of-a-dislocated-total-hip-prosthesis-the-role-of-metal-suppression-mri-a-case-report
#9
Zoe B Cheung, Anik V Patel, Nicholas DeBellis, Douglas B Unis, Carlos L Benitez
CASE: A 68-year-old woman who had undergone a right total hip arthroplasty presented with a right posterior hip dislocation, and subsequently developed an ipsilateral sciatic nerve palsy after closed reduction. Magnetic resonance imaging (MRI) with metal suppression demonstrated sciatic nerve entanglement around the prosthetic femoral neck. A sciatic nerve release was performed, resulting in poor early neurologic recovery. CONCLUSION: Sciatic nerve entanglement following closed reduction of a dislocated total hip prosthesis is a rare injury...
January 10, 2018: JBJS Case Connector
https://www.readbyqxmd.com/read/29318083/a-missed-opportunity-in-bone-health-vitamin-d-and-calcium-use-in-elderly-femoral-neck-fracture-patients-following-arthroplasty
#10
Sheila Sprague, Kim Madden, Gerard Slobogean, Brad Petrisor, Jonathan D Rick Adachi, Earl Bogoch, Ydo V Kleinlugtenbelt, Mohit Bhandari
Introduction: Introduction: Adequate calcium and vitamin D from diet and supplementation is recommended for elderly hip fracture patients. Using data from the multinational hip fracture arthroplasty trial (HEALTH), we determined the proportion of patients who consistently took vitamin D and calcium and which characteristics/prescribing practices were associated with consistency of supplement use. Methods: HEALTH is a multicenter randomized trial of elderly hip fracture patients treated with hemi-arthroplasty and total hip arthroplasty...
December 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29318081/-hidden-preoperative-blood-loss-with-extracapsular-versus-intracapsular-hip-fractures-what-is-the-difference
#11
Katharine D Harper, Paul Navo, Frederick Ramsey, Sainabou Jallow, Saqib Rehman
Purpose: Excessive blood loss with hip fracture management has been shown to result in increased rates of complications. Our goal is to compare blood loss and transfusion rates between patients with intracapsular and extracapsular (both intertrochanteric (IT) and subtrochanteric (ST)) hip fractures. Methods: 472 patients were evaluated over a five-year period. Those who presented to the hospital with a proximal femur fracture (femoral neck, IT or ST) were considered for the study...
December 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/29318009/assessment-of-osteoporosis-using-the-frax-method-and-the-importance-of-vitamin-d-levels-in-copd-patients
#12
Ceyda Anar, Melike Yüksel Yavuz, Filiz Güldaval, Yelda Varol, Dilek Kalenci
Background: The aim of this paper was to evaluate the availability of FRAX for assessing osteoporosis risk, and to demonstrate the importance of vitamin D levels in COPD patients. Methods: Fourty-six males who fulfilled the COPD diagnostic criteria defined by GOLD were included. Age, race, BMI, physical activity frequency, smoking and dietary habits, age at COPD diagnosis, disease duration, fractures history, and medications use were determined. Levels of 25(OH)D were detected...
2018: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/29317966/epithelioid-angiosarcoma-in-femur-a-case-presentation
#13
Yunus Oc, Bekir Eray Kilinc, Rodi Ertugrul, Hasan Basri Sezer, Osman Tugrul Eren
Primary malignant vascular tumors which constitute less than 1% of the primary bone tumors are very rarely encountered. Epithelioid angiosarcoma is a very uncommon subtype of angiosarcomas presenting with an epithelioid phenotype and mimicking carcinomas clinically. These tumors select mostly extra-skeletal locations but rarely bones as their medium. A 31-year-old male patient applied to our clinic with a nonspecific left hip pain. X-ray evaluation revealed a cystic expansile mass in the trochanteric region of the femur extending to the femoral neck...
December 2017: World Journal of Oncology
https://www.readbyqxmd.com/read/29317680/exome-wide-rare-variant-analyses-of-two-bone-mineral-density-phenotypes-the-challenges-of-analyzing-rare-genetic-variation
#14
Jianping Sun, Karim Oualkacha, Vincenzo Forgetta, Hou-Feng Zheng, J Brent Richards, Daniel S Evans, Eric Orwoll, Celia M T Greenwood
Performance of a recently developed test for association between multivariate phenotypes and sets of genetic variants (MURAT) is demonstrated using measures of bone mineral density (BMD). By combining individual-level whole genome sequenced data from the UK10K study, and imputed genome-wide genetic data on individuals from the Study of Osteoporotic Fractures (SOF) and the Osteoporotic Fractures in Men Study (MrOS), a data set of 8810 individuals was assembled; tests of association were performed between autosomal gene-sets of genetic variants and BMD measured at lumbar spine and femoral neck...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29315343/correction-the-treatment-of-femoral-neck-fracture-using-vegf-loaded-nanographene-coated-internal-fixation-screws
#15
Shuo Li, Hengfeng Yuan, Jianfeng Pan, Wenshuai Fan, Liang Zhu, Zuoqin Yan, Changan Guo
[This corrects the article DOI: 10.1371/journal.pone.0187447.].
2018: PloS One
https://www.readbyqxmd.com/read/29313319/early-experience-with-a-tapered-titanium-porous-plasma-sprayed-stem-with-updated-design
#16
Antonio G Manocchio, Keith R Berend, Michael J Morris, Joanne B Adams, Adolph V Lombardi
INTRODUCTION: The Taperloc® Complete femoral stem (Zimmer Biomet, Warsaw, Indiana) builds on the widespread clinical success of the original Taperloc design used since 1982. Enhancements to the Complete design include a lowered caput-collum-diaphyseal (CCD) angle from 138° to 133° for improved offset, optimized neck taper with polished neck flats to increase range of motion, reduced distal geometry to improve proximal canal fill, and gradual off-loading that is the goal of tapered geometry...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29313098/decrease-of-bone-mineral-density-in-japanese-patients-with-non-metastatic-prostate-cancer-treated-with-androgen-deprivation-therapy
#17
Seiichi Kato, Makoto Kawase, Daiki Kato, Takashi Ishida, Masahiro Uno, Yoshinori Fujimoto, Takako Masue, Naruyasu Masue, Takashi Deguchi
The aim of this study was to conduct a cross-sectional survey of investigations related to the bone mineral density (BMD) of both non-metastatic prostate cancer (NMPC) patients who have not yet received androgen deprivation therapy (ADT) and patients receiving prolonged ADT in Japan. Japanese male patients with NMPC who received continuous ADT or who were planning to receive ADT were enrolled in this study. Lumbar spine and femoral neck BMD was measured using dual-energy X-ray absorptiometry (DEXA). To assess patient characteristics, we searched medical records and questionnaires to determine whether they had any factors that could possibly affect BMD...
January 8, 2018: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29307031/the-minimally-invasive-anterolateral-approach-versus-the-traditional-anterolateral-approach-watson-jones-for-hip-hemiarthroplasty-after-a-femoral-neck-fracture-an-analysis-of-clinical-outcomes
#18
Louis de Jong, Taco M A L Klem, Tjallingius M Kuijper, Gert R Roukema
PURPOSE: The minimally invasive (MI) anterolateral approach is a relatively new approach for the treatment of femoral neck fractures with a hemiarthroplasty (HA). There is limited research available presenting clinical outcomes after an HA using the MI approach. Therefore the aim of the present study was to compare clinical outcomes of the MI and traditional anterolateral approaches in patients after HA. METHODS: Data were extracted from a prospective hip fracture database and completed by retrospective review of the electronic medical records...
January 6, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29305636/lower-lean-mass-measured-by-dual-energy-x-ray-absorptiometry-dxa-is-not-associated-with-increased-risk-of-hip-fracture-in-women-the-framingham-osteoporosis-study
#19
Robert R McLean, Douglas P Kiel, Sarah D Berry, Kerry E Broe, Xiaochun Zhang, L Adrienne Cupples, Marian T Hannan
Although muscle mass influences strength in older adults, it is unclear whether low lean mass measured by dual-energy X-ray absorptiometry (DXA) is an independent risk factor for hip fracture. Our objective was to determine the association between DXA lean mass and incident hip fracture risk among 1978 women aged 50 years and older participating in the Framingham Study Original and Offspring cohorts. Leg and total body lean mass (kg) were assessed from whole-body DXA scans collected in 1992-2001. Hip fracture follow-up extended from DXA assessment to the occurrence of fracture, death, drop-out, or end of follow-up in 2007...
January 5, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29305445/outcomes-of-dual-mobility-components-in-total-hip-arthroplasty-a-systematic-review-of-the-literature
#20
REVIEW
B Darrith, P M Courtney, C J Della Valle
AIMS: Instability remains a challenging problem in both primary and revision total hip arthroplasty (THA). Dual mobility components confer increased stability, but there are concerns about the unique complications associated with these designs, as well as the long-term survivorship. MATERIALS AND METHODS: We performed a systematic review of all English language articles dealing with dual mobility THAs published between 2007 and 2016 in the MEDLINE and Embase electronic databases...
January 2018: Bone & Joint Journal
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