keyword
MENU ▼
Read by QxMD icon Read
search

Jungle

keyword
https://www.readbyqxmd.com/read/28619531/-find-your-way-in-the-jungle-of-mabs
#1
H Watier
The rapidly increasing number of approved monoclonal antibodies (mAbs) and the huge number of mAbs in clinical development are a matter of concern for who wants to easily identify targets, indications, mechanisms of action and possible adverse effects. The current nomenclature being of limited interest, simple rationales will be presented for helping practitioners in rapidly classify mAbs depending on their structure-pharmacology relationship and in evaluating their potential effects, particularly in transfusion medicine...
June 12, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28609968/-i-hersilia-i-i-aadi-i-pravalikha-srinivasulu-amp-srinivasulu-2014-a-junior-synonym-of-i-hersilia-savignyi-i-lucas-1836-araneae-hersiliidae
#2
John T D Caleb, G B Pravalikha, Benaiah Ebenezer Johnson, Mitemlu Manyu, Soreiphy Mungkung, Manu Thomas Mathai
The genus Hersilia was established by Audouin in 1826 with H. caudata Audouin, 1826 as the type species. It is the most speciose hersiliid genus presently comprising 79 described species worldwide (World Spider Catalog 2017, version 18). There are seven species known from India: H. aadi Pravalikha, Srinivasulu & Srinivasulu, 2014, H. longivulva Sen et al., 2010, H. orvakalensis Javed et al., 2010, H. savignyi Lucas, 1836, H. striata Wang & Yin, 1985, H. sumatrana (Thorell, 1890), H. tibialis Baehr & Baehr, 1993...
April 18, 2017: Zootaxa
https://www.readbyqxmd.com/read/28594404/precision-medicine-for-hepatocelluar-carcinoma-using-molecular-pattern-diagnostics-results-from-a-preclinical-pilot-study
#3
Rahul Agarwal, Yuan Cao, Klaus Hoffmeier, Nicolas Krezdorn, Lukas Jost, Alejandro Rodriguez Meisel, Ruth Jüngling, Francesco Dituri, Serena Mancarella, Björn Rotter, Peter Winter, Gianluigi Giannelli
The aim of this study was to design a road map for personalizing cancer therapy in hepatocellular carcinoma (HCC) by using molecular pattern diagnostics. As an exploratory study, we investigated molecular patterns of tissues of two tumors from individual HCC patients, which in previous experiments had shown contrasting reactions to the phase 2 transforming growth factor beta receptor 1 inhibitor galunisertib. Cancer-driving molecular patterns encompass - inter alias - altered transcription profiles and somatic mutations in coding regions differentiating tumors from their respective peritumoral tissues and from each other...
June 8, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28589386/navigating-the-jungles-of-tropical-infectious-gastrointestinal-pathology-a-pattern-based-approach-to-the-endoscopic-biopsy
#4
Tomas Slavik, Gregory Y Lauwers
International travels and global human migration have had the unforeseen consequence of increasing the exposure of histopathologists in developed countries to the pathology of tropical infectious disease. The gastrointestinal tract (GIT) is often the primary site of infection due to the faecal-oral route of transmission and the high risk of exposure to contaminated water, food or soil when travelling to these regions. Whilst current microbiologic techniques are far more sensitive than histology in detecting infectious pathogens, the histopathologist nonetheless retains a pivotal role in diagnosing tropical GIT disease...
June 6, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28573253/in-vivo-carbon-tetrachloride-induced-hepatoprotective-and-in-vitro-cytotoxic-activities-of-garcinia-hombroniana-seashore-mangosteen
#5
Nargis Jamila, Naeem Khan, Amir Atlas Khan, Imran Khan, Sadiq Noor Khan, Zainal Amiruddin Zakaria, Melati Khairuddean, Hasnah Osman, Kyong Su Kim
BACKGROUND: Garcinia hombroniana, known as "manggis hutan" (jungle mangosteen) in Malaysia, is distributed in tropical Asia, Borneo, Thailand, Andaman, Nicobar Islands, Vietnam and India. In Malaysia, its ripened crimson sour fruit rind is used as a seasoning agent in curries and culinary dishes. Its roots and leaves decoction is used against skin infections and after child birth. This study aimed to evaluate in vivo hepatoprotective and in vitro cytotoxic activities of 20% methanolic ethyl acetate (MEA) G...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28558694/accurate-characterization-of-the-ifitm-locus-using-miseq-and-pacbio-sequencing-shows-genetic-variation-in-galliformes
#6
Irene Bassano, Swee Hoe Ong, Nathan Lawless, Thomas Whitehead, Mark Fife, Paul Kellam
BACKGROUND: Interferon inducible transmembrane (IFITM) proteins are effectors of the immune system widely characterized for their role in restricting infection by diverse enveloped and non-enveloped viruses. The chicken IFITM (chIFITM) genes are clustered on chromosome 5 and to date four genes have been annotated, namely chIFITM1, chIFITM3, chIFITM5 and chIFITM10. However, due to poor assembly of this locus in the Gallus Gallus v4 genome, accurate characterization has so far proven problematic...
May 30, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28548278/neuropeptide-s-precursor-knockout-mice-display-memory-and-arousal-deficits
#7
Xiaobin Liu, Wei Si, Celia Garau, Kay Jüngling, Hans-Christian Pape, Stefan Schulz, Rainer K Reinscheid
Activation of neuropeptide S (NPS) signaling has been found to produce arousal, wakefulness, anxiolytic-like behaviors, and enhanced memory formation. In order to further study physiological functions of the NPS system, we generated NPS precursor knockout mice by homologous recombination in embryonic stem cells. NPS(-/-) mice were viable, fertile, and anatomically normal, when compared to their wild-type and heterozygous littermates. The total number of NPS neurons-although no longer synthesizing the peptide - was not affected by the knockout, as analyzed in NPS(-/-) /NPS(EGFP) double transgenic mice...
May 26, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28542781/morphological-variation-in-brain-through-domestication-of-fowl
#8
Soichiro Kawabe, Naoki Tsunekawa, Kohei Kudo, Chanin Tirawattanawanich, Fumihito Akishinonomiya, Hideki Endo
Great variations in the size, shape, color, feather structure and behavior are observed among fowl breeds. Because many types of domestic fowls have been bred for various purposes, they are ideal to assess the relationship between brain morphology and avian biology. However, little is known about changes in brain shape that may have occurred during fowl domestication. We analyzed the brains of red jungle fowl and domestic fowl to clarify differences in the brain shape between these breeds, as well as the shape changes associated with size enlargement using three-dimensional geometric morphometrics...
May 24, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28509895/-chronic-malnutrition-among-children-under-five-in-peru-a-spatial-analysis-of-nutritional-data-2010-2016
#9
Akram Hernández-Vásquez, Elena Tapia-López
OBJECTIVE: Peru has implemented various strategies seeking to improve nutritional indicators in children under five years old. However, high prevalence of malnutrition in some regions still remains. The aim of this study was to assess changes in regional prevalence and to determine the presence of district conglomerates with a high prevalence of chronic childhood malnutrition (CCM) in 2010 and 2016. METHODS: A comparative descriptive analysis by regions and a district-level spatial analysis were conducted employing indicators reported by the Nutritional Status Information System...
May 19, 2017: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/28492353/laparoscopy-using-room-air-insufflation-in-a-rural-african-jungle-hospital-the-bongolo-hospital-experience-january-2006-to-december-2013
#10
Zachary O'Connor, Marco Faniriko, Keir Thelander, Jennifer O'Connor, David Thompson, Adrian Park
INTRODUCTION: Carbon dioxide is the standard insufflation gas for laparoscopy. However, in many areas of the world, bottled carbon dioxide is not available. Laparoscopy offers advantages over open surgery and has been practiced using filtered room air insufflation since 2006 at Bongolo Hospital in Gabon, Africa. OBJECTIVE: Our primary goal was to evaluate the safety of room air insufflation related to intraoperative and postoperative complications. Our secondary aim was to review the types of cases performed laparoscopically at our institution...
June 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28456806/navigating-through-the-jungle-of-allergens-features-and-applications-of-allergen-databases
#11
Christian Radauer
The increasing number of available data on allergenic proteins demanded the establishment of structured, freely accessible allergen databases. In this review article, features and applications of 6 of the most widely used allergen databases are discussed. The WHO/IUIS Allergen Nomenclature Database is the official resource of allergen designations. Allergome is the most comprehensive collection of data on allergens and allergen sources. AllergenOnline is aimed at providing a peer-reviewed database of allergen sequences for prediction of allergenicity of proteins, such as those planned to be inserted into genetically modified crops...
2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28431039/genomic-data-for-78-chickens-from-14-populations
#12
Diyan Li, Tiandong Che, Binlong Chen, Shilin Tian, Xuming Zhou, Guolong Zhang, Miao Li, Uma Gaur, Yan Li, Majing Luo, Long Zhang, Zhongxian Xu, Xiaoling Zhao, Huadong Yin, Yan Wang, Long Jin, Qianzi Tang, Huailiang Xu, Mingyao Yang, Rongjia Zhou, Ruiqiang Li, Qing Zhu, Mingzhou Li
Since the domestication of the red jungle fowls ( Gallus gallus ; dating back to ∼10 000 B.P.) in Asia, domestic chickens ( Gallus gallus domesticus ) have been subjected to the combined effects of natural selection and human-driven artificial selection; this has resulted in marked phenotypic diversity in a number of traits, including behavior, body composition, egg production, and skin color. Population genomic variations through diversifying selection have not been fully investigated. The whole genomes of 78 domestic chickens were sequenced to an average of 18-fold coverage for each bird...
June 1, 2017: GigaScience
https://www.readbyqxmd.com/read/28418277/geographical-variation-in-the-skeletal-morphology-of-red-jungle-fowl
#13
H Endo, N Tsunekawa, M Sonoe, T Sasaki, H Ogawa, T Amano, N T Son, V Phimphachanhvongsod, K Kudo, T Yonezawa, F Akishinonomiya
1. The skulls and postcranial skeletons of the red jungle fowl (Gallus gallus) were compared osteometrically between the populations from North and South Vietnam, North and Central Laos and Southeast Bangladesh. The populations include the three subspecies of G. g. spadiceus, G. g. gallus and G. g. murghi and were sampled to reveal the geographical morphological variations among populations in G. gallus. 2. The morphometric characteristics of subspecies murghi could be clearly distinguished from those of the other subspecies using a canonical discriminant analysis...
April 18, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28413836/assessment-of-the-perceived-effects-and-management-challenges-of-mikania-micrantha-invasion-in-chitwan-national-park-buffer-zone-community-forest-nepal
#14
Akriti Khadka
The effects of invasion by Mikania micrantha in the buffer zone of Chitwan National Park (CNP) of Nepal are well documented; however the studies were confined to appraising the perception of household and did not assess the changes in livelihood activities after the invasion. This study presents the effects of invasion of M. micrantha on the livelihood of buffer zone of the Chitwan National Park; hence addressing the gap in information and shows the complex effect of M. micrantha on rural livelihood. The study used a questionnaire survey to 170 households in the CNP of Nepal...
April 2017: Heliyon
https://www.readbyqxmd.com/read/28399853/the-anti-cancer-effects-of-tualang-honey-in-modulating-breast-carcinogenesis-an-experimental-animal-study
#15
Sarfraz Ahmed, Nor Hayati Othman
BACKGROUND: Honey has been shown to have anti-cancer effects, but the mechanism behind these effects is not fully understood. We investigated the role of Malaysian jungle Tualang honey (TH) in modulating the hematological parameters, estrogen, estrogen receptors (ER1) and pro and anti-apoptotic proteins expression in induced breast cancer in rats. METHODS: Fifty nulliparous female Sprague-Dawley rats were used and grouped as follows: Group 0 (healthy normal rats control), Group 1 (negative control; untreated rats), Groups 2, 3 and 4 received daily doses of 0...
April 11, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28396339/poppers-legal-highs-with-questionable-contents-a-case-series-of-poppers-maculopathy
#16
Rebecca Rewbury, Edward Hughes, Robert Purbrick, Stephen Prior, Mark Baron
BACKGROUND: Poppers are volatile alkyl nitrite compounds that are inhaled to enhance sexual experience and for their psychoactive effects. A less well-known side effect is foveal maculopathy, which has emerged following changes in their chemical composition. It is unclear if certain individuals are more susceptible to retinal damage or if there is a relationship between pattern of inhalation and brands used. METHODS: A case series of 12 patients presenting to Sussex Eye Hospital, Brighton, with poppers-related visual impairment...
April 10, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28379963/the-origin-and-evolution-of-fibromelanosis-in-domesticated-chickens-genomic-comparison-of-indonesian-cemani-and-chinese-silkie-breeds
#17
Anik Budhi Dharmayanthi, Yohei Terai, Sri Sulandari, M Syamsul Arifin Zein, Toyoko Akiyama, Yoko Satta
Like Chinese Silkie, Indonesian Ayam Cemani exhibits fibromelanosis or dermal hyperpigmentation and possesses complex segmental duplications on chromosome 20 that involve the endothelin 3 gene, EDN3. A genomic region, DR1 of 127 kb, together with another region, DR2 of 171 kb, was duplicated by unequal crossing over, accompanied by inversion of one DR2. Quantitative PCR and copy number variation analyses on the Cemani genome sequence confirmed the duplication of EDN3. These genetic arrangements are identical in Cemani and Silkie, indicating a single origin of the genetic cause of Fm...
2017: PloS One
https://www.readbyqxmd.com/read/28342344/water-hardness-determines-226-ra-uptake-in-the-tropical-freshwater-mussel
#18
Che Doering, Andreas Bollhöfer
Chemical data for freshwater mussels (Velesunio spp.) and water from 15 sampling sites in the Alligator Rivers Region and Rum Jungle uranium provinces in tropical Northern Australia were analysed to develop a predictive model of radium-226 ((226)Ra) bioaccumulation for variable water calcium (Ca) and magnesium (Mg) concentrations. Application of the model as a (226)Ra screening approach for freshwater mussels in tropical waterbodies potentially impacted by operational or remediated uranium mine sites is discussed in relation to Mudginberri Billabong, located approximately 12 km downstream of Ranger uranium mine in the Alligator Rivers Region...
June 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28327851/-perceptions-on-healthcare-in-people-with-self-identified-mental-health-problems-in-the-rural-areas-of-peru
#19
Javier E Saavedra, Verousckha Uchofen-Herrera
Person-centered health and community health perspectives on its needs and resources are mandatory in healthcare policies in highly cultural diverse contexts. From this point of view, epidemiology needs to be centered not only on the disease, but also on the health diagnosis and its context, including the points of view of people and the community about their problems and needs. This article describes and qualitatively analyzes the views of adults with self-identified mental health disorders (MHD) in rural regions on the coast, highlands, and jungle of Peru, as causal factors, personal resources, and healthcare expectations from health facilities, using the narrative approach of ideographic formulation proposed by the World Psychiatric Association...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28325244/perspectives-on-patient-access-to-radiation-oncology-services-in-south-america
#20
REVIEW
Beatriz Amendola, Aldo Quarneti, Arthur Accioly Rosa, Gustavo Sarria, Marco Amendola
Cancer represents a fast-growing challenge worldwide, and is being recognized as an emerging and critical issue in low- and middle-income countries, such most of South America. This subcontinent is unique for its geography, culture, and ethnical diversity. Most of its countries have large expanses of jungle and desert where underserved population groups including indigenous (native Indians), represent a challenge for cancer care. Many indigent patients have no access to preventive care nor early diagnosis. This results in late presentations with advanced disease and frequently incurable cancer...
April 2017: Seminars in Radiation Oncology
keyword
keyword
73571
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"