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Grehlin Analogue

Cameron Frayling, Ruth Britton, Nicholas Dale
The brain plays a vital role in the regulation of food intake, appetite and ultimately body weight.Neurons in the hypothalamic arcuate nucleus, the ventromedial hypothalamic nuclei(VMH)and the lateral hypothalamus are sensitive to a number of circulating signals such as leptin, grehlin, insulin and glucose. These neurons are part of a network that integrates this information to regulate feeding and appetite. Hypothalamic tanycytes contact the cerebral spinal fluid of the third ventricle and send processes into the parenchyma...
May 1, 2011: Journal of Physiology
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