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Excessive Daytime Sleepiness

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https://www.readbyqxmd.com/read/29126903/the-influence-of-sleep-on-human-hypothalamic-pituitary-adrenal-hpa-axis-reactivity-a-systematic-review
#1
REVIEW
Jens H van Dalfsen, C Rob Markus
Inadequate sleep is highly prevalent and known to decline both physical- and mental health. Literature suggests that altered functioning of the hypothalamic-pituitary-adrenal (HPA) axis might underlie this association. This assumption is mainly based on changes in basal neuroendocrine activity and it is of equal importance to elucidate whether sleep may also influence HPA stress responsiveness. The present review provides a complete outline of recent human studies that have investigated how different aspects of sleep influence cortisol reactivity to laboratory stress...
October 18, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29124630/effectiveness-of-inspiratory-muscle-training-on-sleep-and-functional-capacity-to-exercise-in-obstructive-sleep-apnea-a-randomized-controlled-trial
#2
Adília Karoline Ferreira Souza, Armèle Dornelas de Andrade, Ana Irene Carlos de Medeiros, Maria Inês Remígio de Aguiar, Taciano Dias de Souza Rocha, Rodrigo Pinto Pedrosa, Anna Myrna Jaguaribe de Lima
PURPOSE: The aim of this study was to evaluate the effectiveness of inspiratory muscle training (IMT) on sleep and functional capacity to exercise in subjects with obstructive sleep apnea (OSA). METHODS: This is a controlled, randomized, double-blind study conducted in 16 OSA patients divided into two groups: training (IMT: n = 8) and placebo-IMT (P-IMT: n = 8). IMT was conducted during 12 weeks with a moderate load (50-60% of maximal inspiratory pressure-MIP), while P-IMT used a load < 20% of MPI...
November 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29123432/a-pictorial-sleepiness-and-sleep-apnoea-scale-to-recognize-individuals-with-high-risk-for-obstructive-sleep-apnea-syndrome
#3
Cathrin Edelmann, Ramesh Ghiassi, Deborah R Vogt, Martyn R Partridge, Ramin Khatami, Jörg D Leuppi, David Miedinger
Purpose: The aim of this study was to evaluate the validity of a new pictorial form of a screening test for obstructive sleep apnea syndrome (OSAS) - the pictorial Sleepiness and Sleep Apnoea Scale (pSSAS). Validation was performed in a sample of patients admitted to sleep clinics in the UK and Switzerland. Patients and methods: All study participants were investigated with objective sleep tests such as full-night-attended polysomnography or polygraphy. The pSSAS was validated by taking into account the individual result of the sleep study, sleep-related questionnaires and objective parameters such as body mass index (BMI) or neck circumference...
2017: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29117887/correlates-to-problem-behaviors-in-pediatric-narcolepsy-a-pilot-study
#4
Althea Robinson Shelton, Beth Malow
STUDY OBJECTIVE: Excessive daytime sleepiness, the hallmark of narcolepsy, predisposes patients to serious performance decrements in multiple areas of function. Psychosocial dysfunction has been demonstrated in adults and children with narcolepsy. Several factors could influence psychosocial functioning in children. The objective of this study was to examine neurobehavioral problems in children with narcolepsy and to define associations with these problem behaviors. METHODS: A cross-sectional study was performed where the Child Behavior Checklist (CBCL) was completed by guardians of children (age 18 years or younger) in whom narcolepsy with or without cataplexy was diagnosed (based on the International Classification of Sleep Disorders, Second Edition) between July 2008 and October 2014...
November 1, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29117882/excessive-daytime-sleepiness-in-acute-ischemic-stroke-association-with-restless-legs-syndrome-diabetes-mellitus-obesity-and-sleep-disordered-breathing
#5
Pavel Šiarnik, Katarína Klobučníková, Pavol Šurda, Matúš Putala, Stanislav Šutovský, Branislav Kollár, Peter Turčáni
STUDY OBJECTIVES: Sleep disorders are frequent in stroke patients. The prevalence of sleep-disordered breathing (SDB), excessive daytime sleepiness (EDS), and restless legs syndrome (RLS) among stroke survivors is up to 91%, 72%, and 15%, respectively. Although the relationship between EDS and SDB is well described, there are insufficient data regarding the association of EDS with RLS. The aim of this study was to explore the association between EDS, SDB, and RLS in acute ischemic stroke...
November 1, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29115823/an-overview-of-the-clinical-uses-pharmacology-and-safety-of-modafinil
#6
Eric Murillo-Rodriguez, André Barciela Veras, Nuno Barbosa Rocha, Henning Budde, Sérgio Machado
Modafinil (MOD) is a drug used for the management of excessive daytime sleepiness observed in several sleep disturbances such as shift work sleep disorder, obstructive sleep apnea, restless leg syndrome and narcolepsy. Additionally, a wide scope of medical uses of MOD have been described such as fatigue in subjects with depression as well as patients under chemotherapy. Moreover, there also appear to be a cognitive enhancer drug. In contrast, recent reports have indicated the risk of developing addiction to MOD...
November 8, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29114733/sodium-oxybate-for-excessive-daytime-sleepiness-and-sleep-disturbance-in-parkinson-disease-a-randomized-clinical-trial
#7
Fabian Büchele, Marc Hackius, Sebastian R Schreglmann, Wolfgang Omlor, Esther Werth, Angelina Maric, Lukas L Imbach, Stefan Hägele-Link, Daniel Waldvogel, Christian R Baumann
Importance: Sleep-wake disorders are a common and debilitating nonmotor manifestation of Parkinson disease (PD), but treatment options are scarce. Objective: To determine whether nocturnal administration of sodium oxybate, a first-line treatment in narcolepsy, is effective and safe for excessive daytime sleepiness (EDS) and disturbed nighttime sleep in patients with PD. Design, Setting, and Participants: Randomized, double-blind, placebo-controlled, crossover phase 2a study carried out between January 9, 2015, and February 24, 2017...
November 6, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29108349/excessive-daytime-sleepiness-and-metabolic-syndrome-in-men-with-obstructive-sleep-apnea-a-large-cross-sectional-study
#8
Yiqun Fu, Huajun Xu, Yunyan Xia, Yingjun Qian, Xinyi Li, Jianyin Zou, Yuyu Wang, Lili Meng, Xulan Tang, Huaming Zhu, Huiqun Zhou, Kaiming Su, Dongzhen Yu, Hongliang Yi, Jian Guan, Shankai Yin
Purpose: Excessive daytime sleepiness is a common symptom in obstructive sleep apnea (OSA). Previous studies have showed that excessive daytime sleepiness is associated with some individual components of metabolic syndrome. We performed a large cross-sectional study to explore the relationship between excessive daytime sleepiness and metabolic syndrome in male OSA patients. Methods: A total of 2241 suspected male OSA patients were consecutively recruited from 2007 to 2013...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29092783/determinants-of-policy-decisions-for-non-commercial-drivers-with-osa-an-integrative-review
#9
REVIEW
Dorrie Rizzo, Eva Libman, Laura Creti, Marc Baltzan, Sally Bailes, Catherine Fichten, Gilles Lavigne
Excessive daytime sleepiness and reduced cognitive functioning secondary to obstructive sleep apnea (OSA) have been identified as an important health-related risk in commercial transportation with, possibly, an increased chance of road accidents. This has resulted in a variety of policies and restrictions imposed on commercial drivers. Here we review current knowledge to assess whether available data are sufficient to guide policy decisions concerning restrictions for non-commercial drivers. The review shows that there is a lack of uniformity among different consensus conferences and guidelines as to how to deal with drivers with OSA...
February 20, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29084403/high-frequency-of-sleep-disorders-in-parkinson-s-disease-and-its-relationship-with-quality-of-life
#10
Manoel Alves Sobreira-Neto, Márcio Alexandre Pena-Pereira, Emmanuelle Silva Tavares Sobreira, Marcos Hortes Nisihara Chagas, Regina Maria França Fernandes, Vitor Tumas, Alan Luiz Eckeli
OBJECTIVES: To determine the frequency of major sleep disorders in patients with Parkinson's disease (PD), diagnosed according to the third international classification of sleep disorders, and assess the relationship of those disorders with the quality of life. METHODS: A cross-sectional study was performed involving 88 consecutive patients with PD from outpatient clinic. Participants were subjected to clinical interviews, assessment using standardized scales (Epworth Sleepiness Scale, PD Questionnaire, Pittsburgh sleep quality index (PSQI) and, for individuals with a diagnosis of RLS/WED, International RLS/WED grading scale), and video-polysomnography...
October 30, 2017: European Neurology
https://www.readbyqxmd.com/read/29082906/sleep-quality-among-nurses-in-a-tertiary-hospital-in-north-west-nigeria
#11
Ibrahim Aliyu, Zainab F Ibrahim, Lawal O Teslim, Helen Okhiwu, Igoche David Peter, Godpower Chinedu Michael
BACKGROUND: Sleep is a necessity; it is nourishing, refreshing and healing. The nursing profession is associated with busy and difficult work schedules, especially the running of shifts which has been associated with cardiovascular and metabolic complications. There is a dearth of local data on sleep disorders, especially among nurses. In this study, we evaluated the quality of sleep and the tendency of daytime sleepiness among nurses. SUBJECTS AND METHODS: This study was cross-sectional in nature involving 100 nurses working with Federal Medical Centre Birnin Kebbi, Kebbi State; the study was carried out between October 2016 and February 2017...
July 2017: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29075566/sleep-disturbances-in-taiwanese-patients-with-parkinson-s-disease
#12
Yi-Ying Lin, Rou-Shayn Chen, Chin-Song Lu, Ying-Zu Huang, Yi-Hsin Weng, Tu-Hsueh Yeh, Wey-Yil Lin, June Hung
INTRODUCTION: Sleep disturbance is a common nonmotor symptom of Parkinson's disease (PD) and strongly affects patients' quality of life. The relationship between excessive daytime sleepiness (EDS) and nighttime problems remains uncertain. Arguments persist regarding the risk factors for sleep disturbance among patients with PD. Furthermore, the prevalence of EDS appears to be lower in Asian countries. Herein, we conducted the study to describe the characteristics of sleep problems in a sample of Taiwanese PD patients and delineate the difference with reported sleep disturbances in Caucasian PD patients from the literature...
October 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29074731/sleep-disturbance-in-family-caregivers-of-children-who-depend-on-medical-technology
#13
Krista Keilty, Eyal Cohen, Karen Spalding, Eleanor Pullenayegum, Robyn Stremler
OBJECTIVES: Family caregivers of children who depend on medical technology (CMT) provide highly skilled care up to 24 hours per day. Sleep disruption places family caregivers at risk for poor health and related outcomes that threaten their long-term caregiving capacity. Few studies exist that have measured sleep in family caregivers, and most have relied entirely on subjective measures. METHODS: In a prospective cohort study, family caregivers of CMT (n=42) and caregivers of healthy children (n=43) were recruited...
October 26, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29074223/is-the-epworth-sleepiness-scale-a-useful-tool-for-screening-excessive-daytime-sleepiness-in-commercial-drivers
#14
Simone Baiardi, Chiara La Morgia, Lucia Sciamanna, Alberto Gerosa, Fabio Cirignotta, Susanna Mondini
The significant social and economic impact of excessive daytime sleepiness makes sleep evaluation a primary medical need in commercial drivers. However, the best screening tool is still matter of debate. In our cohort of 221 commercial drivers, only ten (4.5%) had Epworth Sleepiness Scale scores indicative of excessive daytime sleepiness. These findings and the lack of concordance in estimating excessive daytime sleepiness among commercial drivers in previous studies using the same psychometric measure indicate that the Epworth Sleepiness Scale is not a reliable tool...
October 23, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29042002/obstructive-sleep-apnea-syndrome-in-parkinson-s-disease-and-other-parkinsonisms
#15
F Crosta, Giovambattista Desideri, Carmine Marini
An association of obstructive sleep apnea syndrome (OSAS) and other sleep-disordered breathing (SDB) with Parkinson's disease (PD) has been reported in some small studies. In the present study we investigated the occurrence of SDB in a large consecutive outpatient series. This is a case-control study in subjects attending a neurological clinic where all patients were screened for SDB by means of sleep-wake history, Epworth Sleepiness Scale, and full-night polysomnography, when indicated. 3194 patients were recruited...
July 2017: Functional Neurology
https://www.readbyqxmd.com/read/29033827/excessive-sleepiness-and-longer-nighttime-in-bed-increase-the-risk-of-cognitive-decline-in-frail-elderly-subjects-the-mapt-sleep-study
#16
Audrey Gabelle, Laure-Anne Gutierrez, Isabelle Jaussent, Sophie Navucet, Caroline Grasselli, Karim Bennys, Cécilia Marelli, Renaud David, Sandrine Andrieu, Claudine Berr, Bruno Vellas, Yves Dauvilliers
Objective: To identify self-reported sleep-wake disturbances that increase the risk of cognitive decline over 1-year follow-up in frail participants. Background: Risk factors for cognitive impairment need to be better identified especially at earliest stages of the pathogenesis. Sleep-wake disturbances may be critical factors to consider and were thus being assessed in this at-risk population for cognitive decline. Methods: Frail elderly participants aged ≥70 years were selected from a subsample of the Multi-domain Alzheimer Preventive Trial (MAPT) for a sleep assessment (MAPT-sleep study) at 18-month follow-up (M18)...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29031750/the-urge-to-move-and-breathe-the-impact-of-obstructive-sleep-apnea-syndrome-treatment-in-patients-with-previously-diagnosed-clinically-significant-restless-legs-syndrome
#17
Cristiana Silva, Ana Rita Peralta, Carla Bentes
OBJECTIVE: The association between restless legs syndrome (RLS) and obstructive sleep apnea syndrome (OSAS) has seldom been reported. There is one study reporting improvement of RLS symptoms severity in patients naive of treatment after initiation of continuous positive airway pressure (CPAP) for OSAS. The aim of this study was to evaluate the impact of the OSAS treatment in patients with previously diagnosed, clinically significant RLS in a usual clinical setting. METHODS: This was a retrospective study of RLS patients from a sleep clinic with a concomitant or subsequent diagnosis of OSAS...
October 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29019051/the-link-between-narcolepsy-and-autonomic-cardiovascular-dysfunction-a-translational-perspective
#18
REVIEW
Chiara Berteotti, Alessandro Silvani
Narcolepsy is a rare disease that entails excessive daytime sleepiness, often associated with sudden episodes of muscle weakness known as cataplexy. Narcolepsy with cataplexy (NC) is due to the loss of hypothalamic neurons that release the neuropeptides orexin A and B. Orexin neuron projections prominently target brain structures involved in wake-sleep state switching and the central autonomic network. This review provides an updated summary of the links between NC and autonomic cardiovascular dysfunction from a translational perspective...
October 10, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28993975/mood-disorders-are-highly-prevalent-in-patients-investigated-with-a-multiple-sleep-latency-test
#19
Eve J Denton, Maree Barnes, Tom Churchward, Melinda Jackson, Allison Collins, Matthew T Naughton, Eli Dabscheck
PURPOSE: Excessive daytime sleepiness (EDS) is a debilitating symptom which occurs commonly in both primary sleep and mood disorders. The prevalence of mood disorders in patients with EDS, evaluated objectively with a mean sleep latency test (MSLT), has not been reported. We hypothesize that mood disorders are highly prevalent in patients being investigated for EDS. This study aims to report the prevalence of mood disorder in the MSLT population and investigate the association between mood disorder and objective and subjective scores of sleepiness...
October 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28988100/-silent-sleep-apnea-in-dentofacial-deformities-and-prevalence-of-daytime-sleepiness-after-orthognathic-and-intranasal-surgery
#20
Jeffrey C Posnick, Anayo Adachie, Neeru Singh, Elbert Choi
PURPOSE: The purposes of this study were to determine the occurrence of undiagnosed "silent" obstructive sleep apnea (OSA) in dentofacial deformity (DFD) patients at initial surgical presentation and to report on the level of daytime sleepiness in DFD patients with OSA and chronic obstructive nasal breathing (CONB) after undergoing bimaxillary, chin, and intranasal surgery. MATERIALS AND METHODS: A retrospective cohort study of patients with a bimaxillary DFD and CONB was implemented...
September 11, 2017: Journal of Oral and Maxillofacial Surgery
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